| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Buzańska, B Zabłocka, A Dybel, K Domańska-Janik, J Albrech. Delayed induction of apoptosis by ammonia in C6 glioma cells. Neurochemistry international. vol 37. issue 2-3. 2000-08-14. PMID:10812214. |
in this study, c6 glioma cells grown in 2% serum were exposed to 5 mm or 10 mm nh(4)cl (ammonia) for 96 h and tested for the appearance of apoptosis by (a) hoechst staining, (b) tunel reaction and (c) dna ladder, at different times of exposure. |
2000-08-14 |
2023-08-12 |
Not clear |
| A M Gorman, U A Hirt, S Orrenius, S Ceccatell. Dexamethasone pre-treatment interferes with apoptotic death in glioma cells. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683582. |
exposure of d384 human astrocytoma and c6 rat glioma cells to staurosporine induced apoptosis as judged by the formation of condensed nuclei and caspase activation. |
2000-04-20 |
2023-08-12 |
human |
| I Galve-Roperh, C Sánchez, M L Cortés, T Gómez del Pulgar, M Izquierdo, M Guzmá. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nature medicine. vol 6. issue 3. 2000-03-22. PMID:10700234. |
experiments with two subclones of c6 glioma cells in culture showed that cannabinoids signal apoptosis by a pathway involving cannabinoid receptors, sustained ceramide accumulation and raf1/extracellular signal-regulated kinase activation. |
2000-03-22 |
2023-08-12 |
mouse |
| S S Metkar, M Anand, P P Manna, K N Naresh, J J Nadkarn. Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent. Experimental cell research. vol 255. issue 1. 2000-03-14. PMID:10666330. |
we investigated whether cell-permeable, synthetic ceramide (c6 ceramide) could induce apoptosis in fas-resistant hodgkin's disease (hd)-derived cell lines. |
2000-03-14 |
2023-08-12 |
Not clear |
| S S Metkar, M Anand, P P Manna, K N Naresh, J J Nadkarn. Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent. Experimental cell research. vol 255. issue 1. 2000-03-14. PMID:10666330. |
c6 ceramide could induce apoptosis in both fas-resistant cell lines and this was associated with a decrease in bclxl level. |
2000-03-14 |
2023-08-12 |
Not clear |
| T M Timiryasova, J Li, B Chen, D Chong, W H Langridge, D S Gridley, I Fodo. Antitumor effect of vaccinia virus in glioma model. Oncology research. vol 11. issue 3. 1999-12-23. PMID:10527073. |
most of c6 cells infected in vitro with rvv-p53 expressing the tumor suppressor p53 protein showed apoptosis specific morphological changes in dapi-stained nuclei and dna fragmentation pattern on gel electrophoresis; infection with vv induced low level of cell apoptosis. |
1999-12-23 |
2023-08-12 |
mouse |
| S M Anderson, M E Reyland, S Hunter, L M Deisher, K A Barzen, D O Quissel. Etoposide-induced activation of c-jun N-terminal kinase (JNK) correlates with drug-induced apoptosis in salivary gland acinar cells. Cell death and differentiation. vol 6. issue 5. 1999-09-09. PMID:10381634. |
in contrast to the parotid c5 cells, the vast majority of submandibular c6 cells appeared to be resistant to etoposide-induced apoptosis. |
1999-09-09 |
2023-08-12 |
rat |
| T Sato, M G Van Dixhoorn, F A Prins, A Mooney, N Verhagen, Y Muizert, J Savill, L A Van Es, M R Dah. The terminal sequence of complement plays an essential role in antibody-mediated renal cell apoptosis. Journal of the American Society of Nephrology : JASN. vol 10. issue 6. 1999-08-03. PMID:10361862. |
to assess the contribution of the terminal sequence of complement on apoptosis, the studies were performed in complement-sufficient pvg/c (pvg/c+) rats and in rats deficient in complement c6 (pvg/c-). |
1999-08-03 |
2023-08-12 |
mouse |
| T Sato, M G Van Dixhoorn, F A Prins, A Mooney, N Verhagen, Y Muizert, J Savill, L A Van Es, M R Dah. The terminal sequence of complement plays an essential role in antibody-mediated renal cell apoptosis. Journal of the American Society of Nephrology : JASN. vol 10. issue 6. 1999-08-03. PMID:10361862. |
in pvg/c+ rats, apoptosis was associated with deposition of c6 and c5b-9. |
1999-08-03 |
2023-08-12 |
mouse |
| T Sato, M G Van Dixhoorn, F A Prins, A Mooney, N Verhagen, Y Muizert, J Savill, L A Van Es, M R Dah. The terminal sequence of complement plays an essential role in antibody-mediated renal cell apoptosis. Journal of the American Society of Nephrology : JASN. vol 10. issue 6. 1999-08-03. PMID:10361862. |
restoration of the complement system of pvg/c- rats with purified human c6 resulted in an increase of apoptosis at 1 h after injection of er4g from minimal numbers to 239.9 +/- 52.4 tunel+ cells. |
1999-08-03 |
2023-08-12 |
mouse |
| S K Ray, G G Wilford, C V Crosby, E L Hogan, N L Bani. Diverse stimuli induce calpain overexpression and apoptosis in C6 glioma cells. Brain research. vol 829. issue 1-2. 1999-08-02. PMID:10350526. |
diverse stimuli induce calpain overexpression and apoptosis in c6 glioma cells. |
1999-08-02 |
2023-08-12 |
rat |
| S K Ray, G G Wilford, C V Crosby, E L Hogan, N L Bani. Diverse stimuli induce calpain overexpression and apoptosis in C6 glioma cells. Brain research. vol 829. issue 1-2. 1999-08-02. PMID:10350526. |
diverse stimuli induced apoptosis in c6 cells morphologically (chromatin condensation as detected by light microscopy) and biochemically [dna fragmentation as detected by tdt-mediated dutp nick-end labeling (tunel) assay]. |
1999-08-02 |
2023-08-12 |
rat |
| Y Higuchi, S Matsukaw. Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells. Archives of biochemistry and biophysics. vol 363. issue 1. 1999-04-22. PMID:10049497. |
glutathione depletion induces giant dna and high-molecular-weight dna fragmentation associated with apoptosis through lipid peroxidation and protein kinase c activation in c6 glioma cells. |
1999-04-22 |
2023-08-12 |
rat |
| Y Higuchi, S Matsukaw. Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells. Archives of biochemistry and biophysics. vol 363. issue 1. 1999-04-22. PMID:10049497. |
glutathione (gsh) depletion caused by l-buthionine-(s,r)-sulfoximine (bso) induced apoptosis that was recognized by terminal deoxynucleotidyl transferase-mediated dutp-biotin nick endo-labeling (tunel), nuclear dna staining with fluorescence dye, and internucleosomal dna fragmentation in c6 rat glioma cells. |
1999-04-22 |
2023-08-12 |
rat |
| Y Higuchi, S Matsukaw. Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells. Archives of biochemistry and biophysics. vol 363. issue 1. 1999-04-22. PMID:10049497. |
lipid peroxidation and protein kinase c (pk-c) activation were observed during the apoptosis of c6 cells, and these events were inhibited by antioxidants and iron chelators without affecting bso-induced gsh depletion. |
1999-04-22 |
2023-08-12 |
rat |
| J W Choi, S E Jun. Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells. The Journal of pharmacology and experimental therapeutics. vol 289. issue 1. 1999-04-21. PMID:10087052. |
lovastatin-induced proliferation inhibition and apoptosis in c6 glial cells. |
1999-04-21 |
2023-08-12 |
Not clear |
| J W Choi, S E Jun. Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells. The Journal of pharmacology and experimental therapeutics. vol 289. issue 1. 1999-04-21. PMID:10087052. |
in this study, we demonstrated that the cytotoxic effects of lovastatin fall into two categories: suppression of cell growth and induction of apoptosis in c6 glial cells. |
1999-04-21 |
2023-08-12 |
Not clear |
| E J Goetzl, Y Kong, B Me. Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 4. 1999-04-13. PMID:9973477. |
apoptosis elicited by c6 ceramide was inhibited by s1p, but not by lpa, in part because ceramide suppressed expression of edg-2 and edg-4 surface receptors for lpa without affecting edg-3 surface receptors for s1p. |
1999-04-13 |
2023-08-12 |
human |
| H Nakayama, S Kajikawa, J Shinozuka, W P Su, K Do. Possible involvement of DNA methylation in 5-azacytidine-induced neuronal cell apoptosis. Histology and histopathology. vol 14. issue 1. 1999-04-13. PMID:9987659. |
5azc, 5-azadeoxycytidine and 6-azacytidine failed to induce apoptosis in c6 cells. |
1999-04-13 |
2023-08-12 |
Not clear |
| R P Wernyj, M P Mattson, S Christako. Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide. Brain research. Molecular brain research. vol 64. issue 1. 1999-03-02. PMID:9889325. |
expression of calbindin-d28k in c6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide. |
1999-03-02 |
2023-08-12 |
rat |