| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iwona Ciechomska, Beata Pyrzynska, Piotr Kazmierczak, Bozena Kaminsk. Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells. Oncogene. vol 22. issue 48. 2003-12-05. PMID:14576824. |
although treatment with ly294002, a specific inhibitor of pi3 k, decreased the phosphorylation of akt and increased fkhr translocation to the nucleus, these events were not sufficient to induce fasl expression and apoptosis of c6 glioma cells. |
2003-12-05 |
2023-08-12 |
Not clear |
| W Ma, S Chen, Z Ren, W Wang, J Zhang, C Su, R Wang, Y L. [Ganciclovir induces apoptosis of rat C6 glioma cell transduced with HSV-tk gene]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 22. issue 2. 2003-12-04. PMID:12903520. |
[ganciclovir induces apoptosis of rat c6 glioma cell transduced with hsv-tk gene]. |
2003-12-04 |
2023-08-12 |
rat |
| Karina Lawrence Ramos, Alison Colquhou. Protective role of glucose-6-phosphate dehydrogenase activity in the metabolic response of C6 rat glioma cells to polyunsaturated fatty acid exposure. Glia. vol 43. issue 2. 2003-11-18. PMID:12838507. |
the study investigated the effects sublethal pufa doses (90 or 150 microm) may have on rat c6 glioma cell energy metabolism, since an adequate energy supply is essential for cell proliferation, migration, and apoptosis. |
2003-11-18 |
2023-08-12 |
human |
| Karina Lawrence Ramos, Alison Colquhou. Protective role of glucose-6-phosphate dehydrogenase activity in the metabolic response of C6 rat glioma cells to polyunsaturated fatty acid exposure. Glia. vol 43. issue 2. 2003-11-18. PMID:12838507. |
the presence of pufas inhibited c6 cell proliferation and migration, although apoptosis was not induced. |
2003-11-18 |
2023-08-12 |
human |
| Hong Qi, Hong-Zhuan Chen, Zheng-Jun Ji. Caspase 3 gene expression and [Ca2+]i homeostasis underlying desipramine-induced C6 glioma cell apoptosis. Acta pharmacologica Sinica. vol 23. issue 9. 2003-09-26. PMID:12230948. |
caspase 3 gene expression and [ca2+]i homeostasis underlying desipramine-induced c6 glioma cell apoptosis. |
2003-09-26 |
2023-08-12 |
rat |
| Hong Qi, Hong-Zhuan Chen, Zheng-Jun Ji. Caspase 3 gene expression and [Ca2+]i homeostasis underlying desipramine-induced C6 glioma cell apoptosis. Acta pharmacologica Sinica. vol 23. issue 9. 2003-09-26. PMID:12230948. |
to study desipramine (des)-induced apoptosis and regulation of caspase 3 gene expression and [ca2+]i homeostasis in rat glioma c6 cells. |
2003-09-26 |
2023-08-12 |
rat |
| Pratima Sur, Eric Anthony Sribnick, James Michael Wingrave, Mark Walter Nowak, Swapan Kumar Ray, Naren Lal Bani. Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells. Brain research. vol 971. issue 2. 2003-07-03. PMID:12706234. |
estrogen attenuates oxidative stress-induced apoptosis in c6 glial cells. |
2003-07-03 |
2023-08-12 |
rat |
| Pratima Sur, Eric Anthony Sribnick, James Michael Wingrave, Mark Walter Nowak, Swapan Kumar Ray, Naren Lal Bani. Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells. Brain research. vol 971. issue 2. 2003-07-03. PMID:12706234. |
we examined the mechanism of 17beta-estradiol (estrogen)-mediated inhibition of apoptosis in c6 (rat glioma) cells following exposure to hydrogen peroxide (h(2)o(2)). |
2003-07-03 |
2023-08-12 |
rat |
| Pratima Sur, Eric Anthony Sribnick, James Michael Wingrave, Mark Walter Nowak, Swapan Kumar Ray, Naren Lal Bani. Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells. Brain research. vol 971. issue 2. 2003-07-03. PMID:12706234. |
these results indicate a role for estrogen in preventing apoptosis in c6 glial cells exposed to h(2)o(2). |
2003-07-03 |
2023-08-12 |
rat |
| M B Gariboldi, R Ravizza, C Petterino, M Castagnaro, G Finocchiaro, E Mont. Study of in vitro and in vivo effects of the piperidine nitroxide Tempol--a potential new therapeutic agent for gliomas. European journal of cancer (Oxford, England : 1990). vol 39. issue 6. 2003-06-26. PMID:12651210. |
morphological features of apoptosis were apparent in c6 cells following in vitro treatment with tpl. |
2003-06-26 |
2023-08-12 |
mouse |
| Absalom Zamorano, Mónica Lamas, Paula Vergara, José R Naranjo, José Segovi. Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis. Journal of neuroscience research. vol 71. issue 2. 2003-06-25. PMID:12503088. |
expression of gas1 decreased glial proliferation and induced c6 cell apoptosis. |
2003-06-25 |
2023-08-12 |
human |
| Absalom Zamorano, Mónica Lamas, Paula Vergara, José R Naranjo, José Segovi. Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis. Journal of neuroscience research. vol 71. issue 2. 2003-06-25. PMID:12503088. |
while the identity of the caspase(s) responsible for gas1-induced apoptosis in neurons has remained elusive, in c6 glioma cells, overexpression of gas1 reproducibly activated caspase-3. |
2003-06-25 |
2023-08-12 |
human |
| Brad L Upham, Tyler R Koski, Alisa M Rummel, Melinda R Wilson, Anelia Horvath, James E Trosk. Differential roles of 2, 6, and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis. Cancer letters. vol 191. issue 1. 2003-05-08. PMID:12609706. |
a rat liver epithelial cell line treated with ceramides containing a 6 (c6) or 8 (c8) carbon acyl-group were potent inhibitors of gjic and apoptosis, whereas a c2-ceramide was only a weak inhibitor of gjic and strong inducer of apoptosis. |
2003-05-08 |
2023-08-12 |
rat |
| Daila S Gridley, Tatyana M Timiryasova, Glen M Miller, Melba L Andres, Radha Dutta-Roy, Erben J Bayeta, Istvan Fodo. Evaluation of TNF-alpha/Bax gene therapy and radiation against C6 glioma xenografts. Technology in cancer research & treatment. vol 2. issue 1. 2003-04-28. PMID:12625753. |
pgl1-bax was expressed by c6 cells and was correlated with apoptosis, indicating that the construct and the bax protein were functional. |
2003-04-28 |
2023-08-12 |
mouse |
| Théophile A Mobio, Emmanuelle Tavan, Isabelle Baudrimont, Rachid Anane, Maria Rosaria Carratú, Ambaliou Sanni, Messanvi F Gbeassor, Thomas W Shier, Jean-François Narbonne, Edmond E Crepp. Comparative study of the toxic effects of fumonisin B1 in rat C6 glioma cells and p53-null mouse embryo fibroblasts. Toxicology. vol 183. issue 1-3. 2003-02-25. PMID:12504343. |
modifications of dna bases and/or dna fragmentation), cell cycle progression (through two generations) and apoptosis in c6 glioma cells (with normal p53 status) and p53-null mouse embryonic fibroblasts (mef) after incubation with fumonisin b(1) (fb(1)). |
2003-02-25 |
2023-08-12 |
mouse |
| Silvana Belletti, Guido Orlandini, Maria Vittoria Vettori, Antonio Mutti, Jacopo Uggeri, Renato Scandroglio, Rossella Alinovi, Rita Gatt. Time course assessment of methylmercury effects on C6 glioma cells: submicromolar concentrations induce oxidative DNA damage and apoptosis. Journal of neuroscience research. vol 70. issue 5. 2003-01-23. PMID:12424738. |
time course assessment of methylmercury effects on c6 glioma cells: submicromolar concentrations induce oxidative dna damage and apoptosis. |
2003-01-23 |
2023-08-12 |
Not clear |
| H A Leaver, H S Bell, M T Rizzo, J W Ironside, A Gregor, S B Wharton, I R Whittl. Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. Prostaglandins, leukotrienes, and essential fatty acids. vol 66. issue 1. 2003-01-08. PMID:12051954. |
using five glioma models, including primary cell suspensions prepared from 46 human glioma samples and an in vivo rat c6 glioma model, we obtained evidence that, following exposure to hufa, either administered into the medium surrounding human glioma cells or in 16 preparations of multicellular spheroids derived from human and rodent glioma cell lines (c6, mog, u87, u373) or administered intra-tumourally by infusion using osmotic mini-pumps in 48 rats, glioma regression and apoptosis were detected. |
2003-01-08 |
2023-08-12 |
human |
| H A Leaver, H S Bell, M T Rizzo, J W Ironside, A Gregor, S B Wharton, I R Whittl. Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. Prostaglandins, leukotrienes, and essential fatty acids. vol 66. issue 1. 2003-01-08. PMID:12051954. |
additionally, synergy between gamma irradiation and hufa administration was observed in 13 experiments analyzing c6 glioma cell apoptosis in vitro. |
2003-01-08 |
2023-08-12 |
human |
| Wim Wätjen, Hajo Haase, Marta Biagioli, Detmar Beyersman. Induction of apoptosis in mammalian cells by cadmium and zinc. Environmental health perspectives. vol 110 Suppl 5. 2002-12-24. PMID:12426148. |
cadmium-induced dna fragmentation in c6 cells was independent of inhibition of protein kinase a (pka), protein kinase c (pkc), mitogen-activated protein kinase (mapk), phosphatidylinositol-3-kinase, ca-calmodulin-dependent protein kinase, and protein kinase g. zinc at moderate concentrations (10-50 microm) protected against programmed cell death induced by cadmium, whereas deprivation of zinc by the membrane-permeable chelator n,n,n',n-terakis-(2-pyridylmethyl)ethylenediamine (tpen) caused cell death with features characteristic of apoptosis. |
2002-12-24 |
2023-08-12 |
rat |
| Manu Jatana, Shailendra Giri, Avtar K Sing. Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine. Neuroscience letters. vol 330. issue 2. 2002-12-17. PMID:12231442. |
apoptotic positive cells in krabbe brain and induction of apoptosis in rat c6 glial cells by psychosine. |
2002-12-17 |
2023-08-12 |
rat |