All Relations between apoptosis and bax

Publication Sentence Publish Date Extraction Date Species
Yanlei Zheng, Ronghua Hu, Jinrong Hu, Lina Feng, Shi L. Protective effects of butorphanol in oleic acid-endotoxin "two-hit" induced rat lung injury by suppression of inflammation and apoptosis. Scientific reports. vol 14. issue 1. 2024-06-20. PMID:38902260. in addition, butorphanol decreased bax and cleaved caspase-3, increased an antiapoptotic protein (bcl-2), and inhibited the "two-hit" cell apoptosis ratio. 2024-06-20 2024-06-23 rat
Ji-Hee Kim, Kyu-Hee Hwang, Seong-Heon Kim, Hi-Ju Kim, Jung-Min Kim, Mi-Young Lee, Seung-Kuy Cha, Jinhee Le. Particulate Matter-Induced Neurotoxicity: Unveiling the Role of NOX4-Mediated ROS Production and Mitochondrial Dysfunction in Neuronal Apoptosis. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892302. this increase in mitochondrial ros triggers the opening of the mitochondrial permeability transition pore (mptp), leading to apoptosis through key mediators, including caspase3, bax, and bcl2. 2024-06-19 2024-06-21 human
Yinwen Hong, Xueliang Sun, Lijuan L. Loureirin B inhibits Cervical Cancer Development by Blocking PI3K/AKT Signaling Pathway: Network Pharmacology Analysis and Experimental Validation. Applied biochemistry and biotechnology. 2024-06-18. PMID:38888697. compared to the cell apoptosis rate of 2.63% in control group, lb increased it to 6.59% via upregulating bax and suppressing bcl-2 expressions. 2024-06-18 2024-06-21 Not clear
Yanju Bi, Haidong Wei, Tingting Yu, Xiaojing Li, Shiwen X. New insights into resveratrol attenuates hepatotoxicity in emamectin benzoate-exposed grass carp (Ctenopharyngodon idella) via NO system/NF-κB signaling pathway. Pesticide biochemistry and physiology. vol 202. 2024-06-15. PMID:38879332. in addition, compared with the con group, the results of flow cytometry and dansylcadaverine (mdc) staining showed a significant increase in apoptosis and autophagy in the emb-exposed group (p < 0.05) with the activation of the b-cell lymphoma-2 (bcl-2)/bcl-2 associated x (bax)/cysteine-aspartic acid protease 3 (caspase-3)/cysteine-aspartic acid protease 9 (caspase-9) pathway and microtubule-associated protein light chain 3 (lc3)/sequestosome 1 (p62)/beclin1 pathway. 2024-06-15 2024-06-18 Not clear
Aurélien Haustrate, Clément Cordier, George Shapovalov, Adriana Mihalache, Emilie Desruelles, Benjamin Soret, Nadège Charlène Essonghé, Corentin Spriet, Maya Yassine, Alexandre Barras, Johanna Marines, Lindsay B Alcaraz, Sabine Szunerits, Gautier Robin, Pierre Gosset, Natalia Prevarskaya, V'yacheslav Lehen'ky. Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression. Cell death & disease. vol 15. issue 6. 2024-06-15. PMID:38879621. mab82 decreased pca survival rate in vitro by 71% at 12 µg/ml via inducing cell death through the apoptosis cascade via activation of the protease calpain, following bax activation, mitochondria enlargement, and loss of cristae, cyt c release, pro-caspase 9 cleavage with the subsequent activation of caspases 3/7. 2024-06-15 2024-06-18 mouse
Kazim Husain, Domenico Coppola, Chung S Yang, Mokenge P Malaf. Effect of vitamin E δ-tocotrienol and aspirin on Wnt signaling in human colon cancer stem cells and in adenoma development in APCmin/+ mice. Carcinogenesis. 2024-06-15. PMID:38877828. in addition, dt3 and/or aspirin-induced apoptosis was associated with cleaved parp, elevated levels of cytosolic cytochrome c and bax, and depletion of anti-apoptotic protein bcl-2 in ccscs. 2024-06-15 2024-06-17 mouse
Peng Niu, Fei Huang, Jie Wang, Jia-Jia Suo, Jie-Ru Wang, Di Fang, Chun-Mei Han, Qing-Hua Ga. Effects of melatonin on sperm quality, enzyme activity, antioxidant gene expression and fertility of cryopreserved bovine semen. Theriogenology. vol 226. 2024-06-14. PMID:38875920. meanwhile, the mrna expression of antioxidant genes sod2, cat and gpx increased in the 0.3 mg/ml mlt treatment group, and the mrna expression of apoptosis genes caspase-3 and bax were significantly reduced. 2024-06-14 2024-06-17 cat
Ana Dias-Carvalho, Mariana Ferreira, Ana Reis-Mendes, Rita Ferreira, Maria de Lourdes Bastos, Eduarda Fernandes, Susana Isabel Sá, João Paulo Capela, Félix Carvalho, Vera Marisa Cost. Doxorubicin-induced neurotoxicity differently affects the hippocampal formation subregions in adult mice. Heliyon. vol 10. issue 11. 2024-06-13. PMID:38868005. concerning the apoptosis pathway, whereas bax increased in the dox9 group, it decreased in the dox18 group. 2024-06-13 2024-06-15 mouse
Warumporn Yingsunthonwattana, Pakkakul Sangsuriya, Premruethai Supungul, Anchalee Tassanakajo. Litopenaeus vannamei heat shock protein 90 (LvHSP90) interacts with white spot syndrome virus protein, WSSV322, to modulate hemocyte apoptosis during viral infection. Fish & shellfish immunology. 2024-06-13. PMID:38871140. moreover, the co-silencing of lvhsp90 and wssv322 triggered apoptosis by the mitochondrial pathway, resulting in the upregulation of pro-apoptotic protein expression (bax) and the downregulation of anti-apoptotic protein expression (bcl, akt). 2024-06-13 2024-06-16 Not clear
Jie Xu, Shouzhu Xu, Jiayin Luo, Shihao Zhang, Dongdong Wu, Qifan Yang, Rourou Fang, Chuandao Shi, Qiling Liu, Jing Zha. Epigallocatechin-3-gallate alleviates ethanol-induced endothelia cells injury partly through alteration of NF-κB translocation and activation of the Nrf2 signaling pathway. Biological & pharmaceutical bulletin. 2024-06-12. PMID:38866477. the findings revealed that a concentration of 20.0 mm of ethanol reduced cell viability and bcl-2 expression, while increasing cell apoptosis, intracellular ros levels, mitochondrial depolarization, and the expression of bax and cleaved-caspase-3 in endothelial cells. 2024-06-12 2024-06-15 Not clear
Zhao-Da Duan, Li-Yang Zheng, Qiu-Ye Jia, Hao-Lun Chen, Dong-Yao Xu, Yu-Jia Yang, Zhi Qi, Li Yang, Chun-Yun W. Effect of scutellarin on BV-2 microglial-mediated apoptosis in PC12 cells via JAK2/STAT3 signalling pathway. Scientific reports. vol 14. issue 1. 2024-06-11. PMID:38862696. we observed that pc12 cells apoptosis in cm was significantly increased, the expression and fluorescence intensity of the pro-apoptotic protein bax and apoptosis-related protein cleaved caspase-3 were increased, and expression of the anti-apoptotic protein b-cell lymphoma-2 (bcl-2) was decreased. 2024-06-11 2024-06-14 Not clear
Zhao-Da Duan, Li-Yang Zheng, Qiu-Ye Jia, Hao-Lun Chen, Dong-Yao Xu, Yu-Jia Yang, Zhi Qi, Li Yang, Chun-Yun W. Effect of scutellarin on BV-2 microglial-mediated apoptosis in PC12 cells via JAK2/STAT3 signalling pathway. Scientific reports. vol 14. issue 1. 2024-06-11. PMID:38862696. after treatment with scutellarin, pc12 cells apoptosis as well as cleaved caspase-3 and bax protein expression and fluorescence intensity decreased. 2024-06-11 2024-06-14 Not clear
Ashrakt H Abdelhamid, Eman M Mantawy, Riham S Said, Ebtehal El-Demerdas. Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway. Toxicology and applied pharmacology. 2024-06-10. PMID:38857790. moreover, saxa abrogated radiation-induced hippocampal neuronal apoptosis through downregulating proapoptotic bcl-2 associated x-protein (bax) and upregulating antiapoptotic b-cell lymphoma 2 (bcl-2) expressions and eventually diminishing expression of cleaved caspase 3. 2024-06-10 2024-06-14 rat
Alexander V Sirotkin, Zuzana Fabová, Barbora Loncová, Kristína Popovičová, Miroslav Bauer, Maroua Jalouli, Abdel Halim Harrat. The microRNA miR-152 can mitigate and prevent the toxic effect of benzene on porcine ovarian cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 99. 2024-06-08. PMID:38815736. the expression of mir-152; viability; proliferation (cell proliferation and expression of mrnas and accumulation of pcna and cyclin b1); apoptosis (expression of mrnas and accumulation of bax and caspase 3; and the proportion of cells with fragmented dna); and release of progesterone, estradiol and igf-i were analyzed via rt-qpcr; the trypan blue exclusion test; quantitative immunocytochemistry; brdu; xtt; tunel assays; and elisa. 2024-06-08 2024-06-11 Not clear
Alexander V Sirotkin, Zuzana Fabová, Barbora Loncová, Maria Bauerová, Abdel Halim Harrat. The adipokines progranulin and omentin can directly regulate feline ovarian granulosa cell functions. Research in veterinary science. vol 175. 2024-06-06. PMID:38843689. for this purpose, we investigated the effects of the addition of progranulin and omentin (0, 0.1, 1, or 10 ng/ml) on the proliferation (accumulation of pcna and cyclin b1), apoptosis (accumulation of bax and caspase 3) and progesterone release of cultured feline ovarian granulosa cells by quantitative immunocytochemistry and enzyme-linked immunosorbent assays (elisas). 2024-06-06 2024-06-10 Not clear
Peng Sun, Kang Huo, Fude Liu, Yawen Cheng, Chen Chen, Jianfeng Han, Jia Y. Regulation and molecular mechanism of adiponectin on the proliferation, apoptosis, autophagy, and chemosensitivity of LN18 Glioma cell line. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 6. 2024-06-05. PMID:38836664. moreover, adiponectin inhibits the proliferation rate of the pten wild-type glioma cell line ln18, enhances the expression of cleaved caspase3 and bax, and significantly elevates the apoptosis rate, as evidenced by annexinv/pi flow cytometry. 2024-06-05 2024-06-07 Not clear
Jianping Chen, Xuehua Chen, Anqi Tang, Zhuo Wang, Kit-Leong Cheong, Xiaofei Liu, Saiyi Zhon. Chondroitin sulfate-functionalized selenium nanoparticle-induced S-phase cell cycle arrest and apoptosis in HeLa Cells. Journal of food science. 2024-06-05. PMID:38837700. moreover, secs increased the level of bax and decreased the expression of bcl-2, resulting in the release of cytochrome c from mitochondria and activating caspase-3/8/9 for caspase-dependent apoptosis. 2024-06-05 2024-06-08 Not clear
Monika Pebam, Sajmina Khatun, Mohammad Sadik Ali, Aditya Srivastava, Aravind Kumar Renga. Self-assembled IR dye/mitoxantrone loaded Porphysomes nanosystem for enhanced combinatorial chemo-photothermal cancer therapy. Colloids and surfaces. B, Biointerfaces. vol 241. 2024-06-05. PMID:38838443. the activation of p53-dependent apoptosis pathways was vividly expressed, evidenced by the upregulation of bax and increased pattern of caspase-3 cleavage. 2024-06-05 2024-06-08 Not clear
Mengxia Shen, Jiafeng Fu, Yunna Zhang, Yanfen Chang, Xiaohong Li, Haipeng Cheng, Yujia Qiu, Min Shao, Yang Han, Yan Zhou, Ziqiang Lu. A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX. Aging cell. 2024-06-04. PMID:38831635. a novel senolytic drug for pulmonary fibrosis: btsa1 targets apoptosis of senescent myofibroblasts by activating bax. 2024-06-04 2024-06-06 Not clear
Mengxia Shen, Jiafeng Fu, Yunna Zhang, Yanfen Chang, Xiaohong Li, Haipeng Cheng, Yujia Qiu, Min Shao, Yang Han, Yan Zhou, Ziqiang Lu. A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX. Aging cell. 2024-06-04. PMID:38831635. in this study, we demonstrated that senescent myofibroblasts are resistant to apoptosis by upregulating the proapoptotic protein bax and antiapoptotic protein bcl-2 and bcl-xl, leading to bax inactivation. 2024-06-04 2024-06-06 Not clear