All Relations between apoptosis and atr
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| E J Brown, D Baltimor. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes & development. vol 14. issue 4. 2000-03-30. PMID:10691732. | in culture, atr(-/-) blastocysts cells continue to cycle into mitosis for 2 days but subsequently fail to expand and die of caspase-dependent apoptosis. | 2000-03-30 | 2023-08-12 | mouse |
| E J Brown, D Baltimor. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes & development. vol 14. issue 4. 2000-03-30. PMID:10691732. | importantly, caspase-independent chromosome breaks are observed in atr(-/-) cells prior to widespread apoptosis, implying that apoptosis is caused by a loss of genomic integrity. | 2000-03-30 | 2023-08-12 | mouse |
| G C Smith, F d'Adda di Fagagna, N D Lakin, S P Jackso. Cleavage and inactivation of ATM during apoptosis. Molecular and cellular biology. vol 19. issue 9. 1999-09-10. PMID:10454555. | here, we study the effect of apoptosis on the integrity of two proteins that have critical roles in dna damage signalling, cell cycle checkpoint controls, and genome maintenance-the product of the gene defective in ataxia telangiectasia, atm, and the related protein atr. | 1999-09-10 | 2023-08-12 | Not clear |
| G C Smith, F d'Adda di Fagagna, N D Lakin, S P Jackso. Cleavage and inactivation of ATM during apoptosis. Molecular and cellular biology. vol 19. issue 9. 1999-09-10. PMID:10454555. | we find that atm but not atr is specifically cleaved in cells induced to undergo apoptosis by a variety of stimuli. | 1999-09-10 | 2023-08-12 | Not clear |