Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Lingling Zhang, Ping Wu, Luyan Zhang, Nagaraja SreeHarsha, Anurag Mishra, Xinyou S. Ameliorative effect of rosiglitazone, a peroxisome proliferator gamma agonist on adriamycin-induced cardio toxicity via suppressing oxidative stress and apoptosis. IUBMB life. vol 72. issue 4. 2021-06-21. PMID:31660680. |
while in apoptosis parameters, rsg treatment in adm rats significantly diminished a cleaved caspase-3 and bax expression as well as expanded bcl-2 expression when contrasted with adm group of rats. |
2021-06-21 |
2023-08-13 |
rat |
Dominic Henn, Kellen Chen, Zeshaan N Maan, Autumn H Greco, Sylvia E Moortgat Illouz, Clark A Bonham, Janos A Barrera, Artem A Trotsyuk, Jagannath Padmanabhan, Arash Momeni, Derrick C Wan, Dung Nguyen, Michael Januszyk, Geoffrey C Gurtne. Cryopreserved human skin allografts promote angiogenesis and dermal regeneration in a murine model. International wound journal. vol 17. issue 4. 2021-06-02. PMID:32227459. |
chsa implantation largely preserved the cellularity of the overlying murine dermis, whereas adm was associated with a significantly higher rate of cellular apoptosis, identified by cleaved caspase-3 staining, and a stronger dendritic cell infiltration of the murine dermis. |
2021-06-02 |
2023-08-13 |
mouse |
C-Q Liang, Y-M Fu, Z-Y Liu, B-R Xing, Y Jin, J-L Huan. The effect of miR-224 down-regulation on SW80 cell proliferation and apoptosis and weakening of ADM drug resistance. European review for medical and pharmacological sciences. vol 24. issue 14. 2021-03-04. PMID:32744680. |
the effect of mir-224 down-regulation on sw80 cell proliferation and apoptosis and weakening of adm drug resistance. |
2021-03-04 |
2023-08-13 |
Not clear |
C-Q Liang, Y-M Fu, Z-Y Liu, B-R Xing, Y Jin, J-L Huan. The effect of miR-224 down-regulation on SW80 cell proliferation and apoptosis and weakening of ADM drug resistance. European review for medical and pharmacological sciences. vol 24. issue 14. 2021-03-04. PMID:32744680. |
since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "the effect of mir-224 down-regulation on sw80 cell proliferation and apoptosis and weakening of adm drug resistance, by c.-q. |
2021-03-04 |
2023-08-13 |
Not clear |
L-Z Chen, Z Ding, Y Zhang, S-T He, X-H Wan. MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance. European review for medical and pharmacological sciences. vol 24. issue 6. 2020-11-20. PMID:32271394. |
mir-203 over-expression promotes prostate cancer cell apoptosis and reduces adm resistance. |
2020-11-20 |
2023-08-13 |
Not clear |
L-Z Chen, Z Ding, Y Zhang, S-T He, X-H Wan. MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance. European review for medical and pharmacological sciences. vol 24. issue 6. 2020-11-20. PMID:32271394. |
the article "mir-203 over-expression promotes prostate cancer cell apoptosis and reduces adm resistance, by chen lz, ding z, zhang y, he st, wang xh, published in eur rev med pharmacol sci. |
2020-11-20 |
2023-08-13 |
Not clear |
Boxue Ren, Lei Ye, Jianwei Gong, Huanhuan Ren, Yangfang Ding, Xiaoyu Chen, Xiaona Liu, Peng Lu, Fei Wei, Wenjuan Xu, Qiusheng Zheng, Defang L. Alteronol Enhances the Anti-tumor Activity and Reduces the Toxicity of High-Dose Adriamycin in Breast Cancer. Frontiers in pharmacology. vol 10. 2020-09-29. PMID:31001113. |
moreover, co-treatment of alteronol and adm (i) remarkably activated p38 and jnk kinases, (ii) elevated ros levels, (iii) triggered mitochondrial dysfunction, (iv) released cytochrome c into the cytoplasm, (v) upregulated apoptosis-related proteins, e.g., cleaved parp, bax, and cleaved caspase-3/9, and (vi) downregulated the expression of bcl-2, followed by apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
Xitao Gao, Mei Wang, Yanyan Zhang, Zhi Xu, Jiaji Ding, Jinhai Tan. MicroRNA-16 sensitizes drug-resistant breast cancer cells to Adriamycin by targeting Wip1 and Bcl-2. Oncology letters. vol 18. issue 3. 2020-09-29. PMID:31452770. |
overexpression of mir-16 in mcf-7/a was associated with a sharp downregulation of wip1 and bcl-2 expression, leading to increased adm-induced cell apoptosis and sensitization of mcf-7/a cells to adm treatment. |
2020-09-29 |
2023-08-13 |
Not clear |
Wenjun Liu, Juan He, Yiling Yang, Qulian Guo, Fei Ga. Upregulating miR-146a by physcion reverses multidrug resistance in human chronic myelogenous leukemia K562/ADM cells. American journal of cancer research. vol 6. issue 11. 2020-09-28. PMID:27904770. |
in conclusion, this present study showed that mir-146a conferred adm resistance in cml cells and physcion could improve the sensitivity of k562/adm cells by enhancing apoptosis via upregulating mir-146a. |
2020-09-28 |
2023-08-13 |
human |
Zhongxin Feng, Qi Che. Raised CD40L expression attenuates drug resistance in Adriamycin-resistant THP-1 cells. Experimental and therapeutic medicine. vol 19. issue 3. 2020-09-28. PMID:32104283. |
the results revealed that the protein expression levels of mrp1 and p-gp were downregulated by raised cd40l expression and that the combination of raised cd40l expression with daunorubicin (dnr), a drug from which adm is derived, significantly increased the extent of cell apoptosis, indicating that drug resistance was effectively attenuated by cd40l. |
2020-09-28 |
2023-08-13 |
human |
J-J Wang, J-P Y. miR-181a down-regulates MAP2K1 to enhance adriamycin sensitivity in leukemia HL-60 cells. European review for medical and pharmacological sciences. vol 23. issue 6. 2020-08-25. PMID:30964176. |
this study aimed to investigate the role of mir-181a in regulating map2k1 expression, the effects on leukemic cell proliferation, apoptosis, and adriamycin (adm) resistance. |
2020-08-25 |
2023-08-13 |
Not clear |
Yue Yang, Jianxin He, Jing Chen, Li Lin, Yongqi Liu, Cunmin Zhou, Yun Su, Hulai We. Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression. BioMed research international. vol 2019. 2020-07-06. PMID:31976328. |
as a result, cells expressing p53 (r248q) displayed higher cell viability and lower cell apoptosis level upon adm treatment. |
2020-07-06 |
2023-08-13 |
Not clear |
Yue Yang, Jianxin He, Jing Chen, Li Lin, Yongqi Liu, Cunmin Zhou, Yun Su, Hulai We. Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression. BioMed research international. vol 2019. 2020-07-06. PMID:31976328. |
however, combination of dha and adm treatment decreased cell viability and elevated cell apoptosis level in p53 (r248q)-expressing hep3b cells. |
2020-07-06 |
2023-08-13 |
Not clear |
Feifei Wang, Zhewen Zhang, Wing Ting Leung, Jing Chen, Juan Yi, Chunmei Ying, Minmin Yuan, Mingyan Wang, Na Zhang, Xuemin Qiu, Ling Wang, Hulai We. Hydroxychloroquine reverses the drug resistance of leukemic K562/ADM cells by inhibiting autophagy. Molecular medicine reports. vol 20. issue 4. 2020-02-19. PMID:31485616. |
collectively, these findings indicated that the inhibition of autophagy significantly promoted the sensitivity of k562/adm cells to adm by facilitating apoptosis. |
2020-02-19 |
2023-08-13 |
Not clear |
Ting Zhang, Liang He, Wei Sun, Yuan Qin, Ping Zhang, Hao Zhan. 1,25‑Dihydroxyvitamin D3 enhances the susceptibility of anaplastic thyroid cancer cells to adriamycin‑induced apoptosis by increasing the generation of reactive oxygen species. Molecular medicine reports. vol 20. issue 3. 2020-02-04. PMID:31524258. |
nac treatment inhibited the expression of cleaved caspase‑3 in atc cells, and reduced apoptosis in cells that were pretreated with 1,25(oh)2d3 and adm. |
2020-02-04 |
2023-08-13 |
Not clear |
J-Y Zhang, Y-N Li, X Mu, Z-L Pan, W-B Li. Targeted regulation of miR-195 on MAP2K1 for suppressing ADM drug resistance in prostate cancer cells. European review for medical and pharmacological sciences. vol 22. issue 24. 2019-12-11. PMID:30575899. |
this study aimed to investigate the effect of mir-195 on the proliferation, apoptosis and adriamycin (adm) resistance of prostate cancer cells. |
2019-12-11 |
2023-08-13 |
Not clear |
Jian-Hui Qiao, Hui-Sheng Ai, Guang-Xian Liu, Jing Zhang, Li Zho. [The Effects of Cyclosporin A on Leukemia Cells In Vitro] Zhongguo shi yan xue ye xue za zhi. vol 9. issue 3. 2019-11-20. PMID:12578596. |
the results showed that 1.0 mg/l csa alone have no effect on the survival of k562 and k562/adm cell lines, but it could enhance the chemotherapy sensitivity of the 2 cell lines, and accelerate the apoptosis induced by adm. |
2019-11-20 |
2023-08-12 |
Not clear |
L-Z Chen, Z Ding, Y Zhang, S-T He, X-H Wan. MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance. European review for medical and pharmacological sciences. vol 22. issue 12. 2019-11-14. PMID:29949147. |
mir-203 over-expression promotes prostate cancer cell apoptosis and reduces adm resistance. |
2019-11-14 |
2023-08-13 |
Not clear |
L-Z Chen, Z Ding, Y Zhang, S-T He, X-H Wan. MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance. European review for medical and pharmacological sciences. vol 22. issue 12. 2019-11-14. PMID:29949147. |
this study explored the role of mir-203 in regulating prostate cancer cell proliferation, apoptosis, and adm resistance through affecting mek1 expression. |
2019-11-14 |
2023-08-13 |
Not clear |
Yi-Pin Lv, Liu-Sheng Peng, Qi-Hong Wang, Na Chen, Yong-Sheng Teng, Ting-Ting Wang, Fang-Yuan Mao, Jin-Yu Zhang, Ping Cheng, Yu-Gang Liu, Hui Kong, Xiao-Long Wu, Chuan-Jie Hao, Weisan Chen, Jiang Zhu, Bin Han, Qiang Ma, Ke Li, Quanming Zou, Yuan Zhuan. Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression. Cell death & disease. vol 9. issue 10. 2019-11-13. PMID:30305610. |
tumor-derived adrenomedullin (adm) induced mast cell degranulation via pi3k-akt signaling pathway, which effectively promoted the proliferation and inhibited the apoptosis of gc cells in vitro and contributed to the growth and progression of gc tumors in vivo, and the effect could be reversed by blocking interleukin (il)-17a production from these mast cells. |
2019-11-13 |
2023-08-13 |
Not clear |