| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew N Hill, Wing-Sze Vanessa Ho, Cecilia J Hillard, Boris B Gorzalk. Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 12. 2009-03-05. PMID:18974922. |
these data suggest that monoaminergic neurotransmission can regulate the endocannabinoid system and further indicates a role of the endocannabinoid system in affective illness and its treatment. |
2009-03-05 |
2023-08-12 |
rat |
| Patrick D Skosnik, Sohee Park, Laura Dobbs, Wendi L Gardne. Affect processing and positive syndrome schizotypy in cannabis users. Psychiatry research. vol 157. issue 1-3. 2008-03-25. PMID:17897720. |
while cannabis is associated with positive syndrome schizophrenia (sz), it is unclear whether cannabinoids are also related to negative symptoms such as affective blunting. |
2008-03-25 |
2023-08-12 |
Not clear |
| Matthew N Hill, Alasdair M Barr, W-S Vanessa Ho, Erica J Carrier, Boris B Gorzalka, Cecilia J Hillar. Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. Journal of neurochemistry. vol 103. issue 1. 2007-11-07. PMID:17561935. |
collectively, these data demonstrate that ecs treatment results in a down-regulation of cortical and an up-regulation of subcortical endocannabinoid activity, illustrating the possibility that the role of the endocannabinoid system in affective illness may be both complex and regionally specific. |
2007-11-07 |
2023-08-12 |
Not clear |
| John D Roberts, Chris Gennings, Margaret Shi. Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine. European journal of pharmacology. vol 530. issue 1-2. 2006-03-21. PMID:16375890. |
the surprisingly limited reported experimental experience in humans does not support a role for delta(9)-thc as an analgesic or as an adjunct to cannabinoid analgesia, except for our finding of synergy limited to the affective component of pain. |
2006-03-21 |
2023-08-12 |
human |
| Matthew N Hill, W-S Vanessa Ho, Sarah E Meier, Boris B Gorzalka, Cecilia J Hillar. Chronic corticosterone treatment increases the endocannabinoid 2-arachidonylglycerol in the rat amygdala. European journal of pharmacology. vol 528. issue 1-3. 2006-03-09. PMID:16324692. |
given the role of amygdalar endocannabinoids in the regulation of emotionality, this suggests that the ability of glucocorticoids to influence affective behavior may involve interactions with regulation of endocannabinoid content. |
2006-03-09 |
2023-08-12 |
rat |
| Sachin Patel, Benjamin F Cravatt, Cecilia J Hillar. Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 3. 2005-04-21. PMID:15280883. |
these data suggest the cea is an important neural substrate subserving the interactions between cannabinoids and environmental stress, and could be relevant to understanding the context-dependent emotional and affective changes induced by marijuana intoxication and the role of endocannabinoid signaling in the modulation of amygdalar activity. |
2005-04-21 |
2023-08-12 |
mouse |
| Eleni T Tzavara, Richard J Davis, Kenneth W Perry, Xia Li, Craig Salhoff, Frank P Bymaster, Jeffrey M Witkin, George G Nomiko. The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions. British journal of pharmacology. vol 138. issue 4. 2003-08-27. PMID:12598408. |
these results suggest that the cortical selectivity in the release of catecholamines, dopamine in particular, induced by the cannabinoid antagonist sr141716a, its procholinergic properties, together with its mild stimulatory effects on serotonin and norepinephrine efflux make similar compounds unique candidates for the treatment of psychosis, affective and cognitive disorders. |
2003-08-27 |
2023-08-12 |
mouse |