| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Cinnamon Bidwell, Renee Martin-Willett, Samantha N Melendez, Luiza Rosa, Gregory Giordano, Kent E Hutchison, Angela D Brya. LOTUS: Protocol for a double-blind placebo controlled randomized trial of hemp-derived cannabidiol for the treatment of cannabis use disorder. PloS one. vol 19. issue 9. 2024-09-30. PMID:39348366. |
some research has found that the non-intoxicating cannabinoid cannabidiol reduces cannabis use and cannabis use disorder-related symptoms, such as affective disturbance and withdrawal. |
2024-09-30 |
2024-10-03 |
Not clear |
| Marieka V DeVuono, Mina G Nashed, Mohammed H Sarikahya, Andrea Kocsis, Kendrick Lee, Sebastian R Vanin, Roger Hudson, Eryn P Lonnee, Walter J Rushlow, Daniel B Hardy, Steven R Laviolett. Prenatal tetrahydrocannabinol and cannabidiol exposure produce sex-specific pathophysiological phenotypes in the adolescent prefrontal cortex and hippocampus. Neurobiology of disease. 2024-07-03. PMID:38960101. |
these phenotypes were associated with sex and treatment-specific neuronal and gene transcriptional alterations in the prefrontal cortex, and ventral hippocampus, regions where the endocannabinoid system is implicated in affective and cognitive development. |
2024-07-03 |
2024-07-10 |
rat |
| Henning Boecker, Marcel Daamen, Angelika Maurer, Luisa Bodensohn, Judith Werkhausen, Marvin Lohaus, Christian Manunzio, Ursula Manunzio, Alexander Radbruch, Ulrike Attenberger, Juergen Dukart, Neeraj Upadhya. Fractional amplitude of low-frequency fluctuations associated with μ-opioid and dopamine receptor distributions in the central nervous system after high-intensity exercise bouts. Frontiers in neuroimaging. vol 3. 2024-03-08. PMID:38455686. |
dopaminergic, opiod and endocannabinoid neurotransmission are thought to play an important role in the neurobiology of acute exercise and, in particular, in mediating positive affective responses and reward processes. |
2024-03-08 |
2024-03-10 |
Not clear |
| Juan F Osuna-Ramos, Josué Camberos-Barraza, Laura E Torres-Mondragón, Ángel R Rábago-Monzón, Alejandro Camacho-Zamora, Marco A Valdez-Flores, Carla E Angulo-Rojo, Alma M Guadrón-Llanos, Verónica J Picos-Cárdenas, Loranda Calderón-Zamora, Javier A Magaña-Gómez, Claudia D Norzagaray-Valenzuela, Feliznando I Cárdenas-Torres, Alberto K De la Herrán-Arit. Interplay between the Glymphatic System and the Endocannabinoid System: Implications for Brain Health and Disease. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139290. |
conversely, the endocannabinoid system, a multifaceted signaling network, is intricately involved in diverse physiological processes and has been associated with modulating synaptic plasticity, nociception, affective states, appetite regulation, and immune responses. |
2023-12-23 |
2023-12-25 |
human |
| Matthew N Hill, Margaret Haney, Cecilia J Hillard, Debra S Karhson, Haley A Vecchiarell. The endocannabinoid system as a putative target for the development of novel drugs for the treatment of psychiatric illnesses. Psychological medicine. 2023-09-06. PMID:37671673. |
cannabis is well established to impact affective states, emotion and perceptual processing, primarily through its interactions with the endocannabinoid system. |
2023-09-06 |
2023-10-07 |
Not clear |
| Nicholas H B Schräder, José C Duipmans, Remco J Renken, Peter Sörös, Karin M Vermeulen, Maria C Bolling, André P Wolf. The C4EB study-Transvamix (10% THC / 5% CBD) to treat chronic pain in epidermolysis bullosa: A protocol for an explorative randomized, placebo controlled, and double blind intervention crossover study. PloS one. vol 17. issue 12. 2022-12-12. PMID:36508401. |
as the pain quality "unpleasantness" delineates eb pain, we hypothesize the modulation of affective pain processing in the brain by way of intervention with cbms comprising the cannabinoids Δ-9-tetrahydrocannabinol and cannabidiol-objectified by functional magnetic resonance imaging (fmri). |
2022-12-12 |
2023-08-14 |
human |
| Marta Kędziora, Serena Boccella, Ida Marabese, Jakub Mlost, Rosmara Infantino, Sabatino Maione, Katarzyna Starowic. Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB Neuropharmacology. vol 222. 2022-11-07. PMID:36341807. |
in the present study, we used a rat model of osteoarthritis induced by intra-articular injection of sodium monoiodoacetate to assess, 28 days post-induction, the contribution of endocannabinoid system on the possible alteration in pain perception and affective behavior, in ltp and monoamine levels in the lateral entorhinal cortex-dentate gyrus pathway. |
2022-11-07 |
2023-08-14 |
rat |
| Jennifer Tat, Kimberly C Thibeault, Danielle N Adank, Samuel W Centanni, Danny G Winder, Erin Calipar. Endocannabinoid regulation of behavior in response to negative affective states associated with alcohol abstinence. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555934. |
endocannabinoid regulation of behavior in response to negative affective states associated with alcohol abstinence. |
2022-05-13 |
2023-08-13 |
mouse |
| b' Nera \\xc5\\xbdigi\\xc4\\x87, Mevludin Hasanovi\\xc4\\x87, Izet Pajevi\\xc4\\x87, Miro Jakovljevi\\xc4\\x8. Possible Consequences of Cannabis Legalization - What Do Research Show? Psychiatria Danubina. vol 33. issue Suppl 4. 2022-03-30. PMID:35354186.' |
acute and chronic cannabis use has been shown to be detrimental to several aspects of psychological and physical health and many experimental studies done on healthy people indicate the potential of Δ9- tetra hydro cannabinoid (thc) in inducing transient, dose-dependent psychotic symptoms, but also affective, behavioral, cognitive, neurovegetative, and psychophysical symptoms. |
2022-03-30 |
2023-08-13 |
Not clear |
| Meredith C Meacham, Alicia L Nobles, D Andrew Tompkins, Johannes Thru. "I got a bunch of weed to help me through the withdrawals": Naturalistic cannabis use reported in online opioid and opioid recovery community discussion forums. PloS one. vol 17. issue 2. 2022-02-08. PMID:35134074. |
future research is warranted with more structured assessments that examines the role of cannabis and cannabinoids in addressing both somatic and affective symptoms of opioid withdrawal. |
2022-02-08 |
2023-08-13 |
Not clear |
| L Cinnamon Bidwell, Renée Martin-Willett, Hollis C Karol. Advancing the science on cannabis concentrates and behavioural health. Drug and alcohol review. vol 40. issue 6. 2021-09-01. PMID:33783029. |
the cannabis sativa l. plant contains hundreds of phytocannabinoids, but putatively of highest importance to public health risk is the psychoactive cannabinoid delta-9-tetrahydrocannabinol (thc), which is associated with risk for cannabis use disorder, affective disturbance, cognitive harm and psychomotor impairment. |
2021-09-01 |
2023-08-13 |
Not clear |
| Aoife M Thornton, Rachel M Humphrey, Daniel M Kerr, David P Finn, Michelle Roch. Increasing Endocannabinoid Tone Alters Anxiety-Like and Stress Coping Behaviour in Female Rats Prenatally Exposed to Valproic Acid. Molecules (Basel, Switzerland). vol 26. issue 12. 2021-07-13. PMID:34207178. |
these data highlight sexual dimorphic behaviours in the vpa model and indicate that enhancing endocannabinoid levels may exacerbate negative affective behaviour in vpa-exposed females. |
2021-07-13 |
2023-08-13 |
rat |
| Nafsika Poulia, Foteini Delis, Charalampos Brakatselos, Panagiotis Lekkas, Nikolaos Kokras, Christina Dalla, Katerina Antonio. Escalating low-dose Δ The European journal of neuroscience. vol 52. issue 1. 2021-06-21. PMID:31626712. |
escalating low-dose Δ cannabinoid administration during adolescence affects various physiological processes, such as motor and affective response, cognitive-related functions and modulates neurotransmitter activity. |
2021-06-21 |
2023-08-13 |
Not clear |
| Louise Corcoran, Darragh Mattimoe, Michelle Roche, David P Fin. Attenuation of fear-conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: Potential role for CB British journal of pharmacology. vol 177. issue 10. 2021-06-21. PMID:31967664. |
here, we studied the role of the endocannabinoid 2-arachidonoyl glycerol (2-ag) within the anterior cingulate cortex (acc; a brain region implicated in the affective component of pain) in fca in rats. |
2021-06-21 |
2023-08-13 |
rat |
| Judit Lazary, Nora Eszlari, Eszter Kriko, Dora Tozser, Peter Dome, J F William Deakin, Gabriella Juhasz, Gyorgy Bagd. Genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants. Neuroscience letters. vol 744. 2021-04-30. PMID:33421489. |
genetic analyses of the endocannabinoid pathway in association with affective phenotypic variants. |
2021-04-30 |
2023-08-13 |
human |
| Koby Cohen, Shiri Rosenzweig, Paola Rosca, Albert Pinhasov, Abraham Weizman, Aviv Weinstei. Personality Traits and Psychotic Proneness Among Chronic Synthetic Cannabinoid Users. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32477173. |
chronic use of synthetic cannabinoids (scs) has been associated with a wide range of negative consequences for health including psychotic and affective disturbances. |
2020-09-28 |
2023-08-13 |
Not clear |
| Samuel W Centanni, Bridget D Morris, Joseph R Luchsinger, Gaurav Bedse, Tracy L Fetterly, Sachin Patel, Danny G Winde. Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 3. 2019-12-18. PMID:30390064. |
endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence. |
2019-12-18 |
2023-08-13 |
mouse |
| Anna N Pushkin, Angeline J Eugene, Valeria Lallai, Alan Torres-Mendoza, J P Fowler, Edison Chen, Christie D Fowle. Cannabinoid and nicotine exposure during adolescence induces sex-specific effects on anxiety- and reward-related behaviors during adulthood. PloS one. vol 14. issue 1. 2019-10-24. PMID:30703155. |
together, these novel findings demonstrate that adolescent exposure to cannabinoids in the presence or absence of nicotine results in altered affective and reward-related behaviors during adulthood. |
2019-10-24 |
2023-08-13 |
mouse |
| Beth Fairfield, Nicola Mammarella, Marica Franzago, Alberto Di Domenico, Liborio Stuppia, Valentina Gatt. A variant on promoter of the cannabinoid receptor 1 gene (CNR1) moderates the effect of valence on working memory. Memory (Hove, England). vol 26. issue 2. 2019-01-14. PMID:28685667. |
here, we aimed to examine whether the endocannabinoid system via cnr1 signaling modulates affective working memory, the memory system that transiently maintains and manipulates emotionally charged material. |
2019-01-14 |
2023-08-13 |
Not clear |
| Kiri L Wills, Marieka V DeVuono, Cheryl L Limebeer, Kiran Vemuri, Alexandros Makriyannis, Linda A Parke. CB₁ receptor antagonism in the bed nucleus of the stria terminalis interferes with affective opioid withdrawal in rats. Behavioral neuroscience. vol 131. issue 4. 2018-04-02. PMID:28714716. |
given the connectivity of these regions and the bnst, the present study sought to determine whether cannabinoid modulation of the bnst would also prevent the affective properties of naloxone precipitated mwd-induced place aversion learning. |
2018-04-02 |
2023-08-13 |
rat |