| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A H Prowse, A R Webster, F M Richards, S Richard, S Olschwang, F Resche, N A Affara, E R Mahe. Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors. American journal of human genetics. vol 60. issue 4. 1997-05-08. PMID:9106522. |
somatic inactivation of the vhl gene in von hippel-lindau disease tumors. |
1997-05-08 |
2023-08-12 |
Not clear |
| B Zbar, T Kishida, F Chen, L Schmidt, E R Maher, F M Richards, P A Crossey, A R Webster, N A Affara, M A Ferguson-Smith, H Brauch, D Glavac, H P Neumann, S Tisherman, J J Mulvihill, D J Gross, T Shuin, J Whaley, B Seizinger, N Kley, S Olschwang, C Boisson, S Richard, C H Lips, M Lerma. Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan. Human mutation. vol 8. issue 4. 1997-03-28. PMID:8956040. |
germline mutations in the von hippel-lindau disease (vhl) gene in families from north america, europe, and japan. |
1997-03-28 |
2023-08-12 |
Not clear |
| J R Wagner, W M Lineha. Molecular genetics of renal cell carcinoma. Seminars in urologic oncology. vol 14. issue 4. 1997-03-06. PMID:8946625. |
one of the most common inheritable forms occurs in von hippel-lindau disease (vhl). |
1997-03-06 |
2023-08-12 |
Not clear |
| P L Dahia, S P Toledo, L M Mulligan, E R Maher, A B Grossman, C En. Mutation analysis of glial cell line-derived neurotrophic factor (GDNF), a ligand for the RET/GDNF receptor alpha complex, in sporadic phaeochromocytomas. Cancer research. vol 57. issue 2. 1997-02-11. PMID:9000574. |
phaeochromocytomas usually occur sporadically but may also be a feature of three autosomal dominantly inherited cancer syndromes, multiple endocrine neoplasia type 2, von hippel-lindau disease (vhl), and, very rarely, type 1 neurofibromatosis. |
1997-02-11 |
2023-08-12 |
Not clear |
| I A Lubensky, J R Gnarra, P Bertheau, M M Walther, W M Linehan, Z Zhuan. Allelic deletions of the VHL gene detected in multiple microscopic clear cell renal lesions in von Hippel-Lindau disease patients. The American journal of pathology. vol 149. issue 6. 1997-01-14. PMID:8952541. |
allelic deletions of the vhl gene detected in multiple microscopic clear cell renal lesions in von hippel-lindau disease patients. |
1997-01-14 |
2023-08-12 |
Not clear |
| J E Lee, S A Curley, R F Gagel, D B Evans, R C Hicke. Cortical-sparing adrenalectomy for patients with bilateral pheochromocytoma. Surgery. vol 120. issue 6. 1997-01-10. PMID:8957496. |
bilateral pheochromocytomas are common in patients with multiple endocrine neoplasia type 2 (men 2) and von hippel-lindau disease (vhl). |
1997-01-10 |
2023-08-12 |
Not clear |
| K Sakat. Alterations of tumor suppressor genes and the H-ras oncogene in oral squamous cell carcinoma. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 25. issue 6. 1997-01-03. PMID:8887073. |
loss of heterozygosity (loh) at the retinoblastoma (rb) gene locus and on chromosomes 3p (vhl; von hippel-lindau disease tumor suppressor gene locus), 5q (apc) and 9p (p16), and h-ras oncogene mutations were also studied in the same samples. |
1997-01-03 |
2023-08-12 |
Not clear |
| F Chen, L Slife, T Kishida, J Mulvihill, S E Tisherman, B Zba. Genotype-phenotype correlation in von Hippel-Lindau disease: identification of a mutation associated with VHL type 2A. Journal of medical genetics. vol 33. issue 8. 1996-12-27. PMID:8863170. |
genotype-phenotype correlation in von hippel-lindau disease: identification of a mutation associated with vhl type 2a. |
1996-12-27 |
2023-08-12 |
Not clear |
| F Chen, L Slife, T Kishida, J Mulvihill, S E Tisherman, B Zba. Genotype-phenotype correlation in von Hippel-Lindau disease: identification of a mutation associated with VHL type 2A. Journal of medical genetics. vol 33. issue 8. 1996-12-27. PMID:8863170. |
a family with von hippel-lindau disease (vhl) type 2a has been shown to have a t to c missense mutation at nucleotide 547 of the vhl gene. |
1996-12-27 |
2023-08-12 |
Not clear |
| R M Hofstra, T Stelwagen, R P Stulp, D de Jong, M Hulsbeek, E J Kamsteeg, A van den Berg, R M Landsvater, A Vermey, W M Molenaar, C J Lips, C H Buy. Extensive mutation scanning of RET in sporadic medullary thyroid carcinoma and of RET and VHL in sporadic pheochromocytoma reveals involvement of these genes in only a minority of cases. The Journal of clinical endocrinology and metabolism. vol 81. issue 8. 1996-12-23. PMID:8768845. |
as pc is a frequent complication in families suffering from von hippel lindau disease, for which mutations of the vhl gene are responsible, we also screened the 5 sporadic pc cases for vhl mutations. |
1996-12-23 |
2023-08-12 |
Not clear |
| C Eng, P A Crossey, L M Mulligan, C S Healey, C Houghton, A Prowse, S L Chew, P L Dahia, J L O'Riordan, S P Toled. Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas. Journal of medical genetics. vol 32. issue 12. 1996-12-05. PMID:8825918. |
phaeochromocytomas may occur sporadically, or as part of the inherited cancer syndromes multiple endocrine neoplasia (men) type 2, von hippel-lindau disease (vhl), and, rarely, in type 1 neurofibromatosis. |
1996-12-05 |
2023-08-12 |
Not clear |
| T Kishida, F Chen, M I Lerman, B Zba. Detection of germline mutations in the von Hippel-Lindau disease gene by the primer specified restriction map modification method. Journal of medical genetics. vol 32. issue 12. 1996-12-05. PMID:8825919. |
von hippel-lindau disease (vhl) is an inherited disorder characterised by a predisposition to develop tumours in the eyes, central nervous system, kidneys, and adrenal glands. |
1996-12-05 |
2023-08-12 |
Not clear |
| J R Gnarra, S Zhou, M J Merrill, J R Wagner, A Krumm, E Papavassiliou, E H Oldfield, R D Klausner, W M Lineha. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 20. 1996-11-25. PMID:8855222. |
the vhl tumor suppressor gene is inactivated in patients with von hippel-lindau disease and in most sporadic clear cell renal carcinomas. |
1996-11-25 |
2023-08-12 |
Not clear |
| J A Brown, J W Segur. A symptomatic testicular cyst in a patient with von Hippel-Lindau disease. Urology. vol 48. issue 3. 1996-10-24. PMID:8804511. |
von hippel-lindau disease (vhl) is an autosomal-dominant condition that often involves cystic changes within many organs, including the epididymis. |
1996-10-24 |
2023-08-12 |
Not clear |
| R W Harrie. A rational approach to radiological screening in von Hippel-Lindau disease. Journal of medical screening. vol 1. issue 2. 1996-10-11. PMID:8790493. |
to optimise radiological screening in von hippel-lindau disease (vhl) while minimising cost and morbidity. |
1996-10-11 |
2023-08-12 |
Not clear |
| F P L. Identification and management of inherited cancer susceptibility. Environmental health perspectives. vol 103 Suppl 8. 1996-09-30. PMID:8741802. |
examples include the rb1 gene for retinoblastoma; the wt1 gene for wilms' tumor; germline p53 mutations in families with the li-fraumeni syndrome; the nf1 and nf2 genes for neuroblastomatosis, types 1 and 2; the vhl gene for renal cancer and other tumors associated with von hippel-lindau disease; the apc gene for adenomatous polyposis coli; the brca1 gene for hereditary breast and ovarian cancer; and the mismatch repair genes for colon and other common cancers. |
1996-09-30 |
2023-08-12 |
human |
| E R Maher, A R Webster, F M Richards, J S Green, P A Crossey, S J Payne, A T Moor. Phenotypic expression in von Hippel-Lindau disease: correlations with germline VHL gene mutations. Journal of medical genetics. vol 33. issue 4. 1996-09-25. PMID:8730290. |
phenotypic expression in von hippel-lindau disease: correlations with germline vhl gene mutations. |
1996-09-25 |
2023-08-12 |
Not clear |
| D Glavac, H P Neumann, C Wittke, H Jaenig, O Masek, T Streicher, F Pausch, D Engelhardt, K H Plate, H Höfler, F Chen, B Zbar, H Brauc. Mutations in the VHL tumor suppressor gene and associated lesions in families with von Hippel-Lindau disease from central Europe. Human genetics. vol 98. issue 3. 1996-09-12. PMID:8707293. |
mutations in the vhl tumor suppressor gene and associated lesions in families with von hippel-lindau disease from central europe. |
1996-09-12 |
2023-08-12 |
Not clear |
| S Nagamori, N Shinohara, A Kashiwagi, M Togashi, H Seki, K Toyota, T Harabayashi, K Nonomura, T Koyanag. [Tumor size and DNA ploidy changes in renal cell carcinomas--flow cytometric analysis of DNA content in renal cell carcinomas associated with von Hippel-Lindau disease]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology. vol 87. issue 4. 1996-08-26. PMID:8691697. |
renal cell carcinomas (rccs) develop in 8-63% of von hippel-lindau disease (vhl) patients, and loss of 3p segments, chromosome aberrations found in 90% of sporadic rccs, has also been observed in rccs associated with vhl. |
1996-08-26 |
2023-08-12 |
Not clear |
| K Foster, R J Osborne, R A Huddart, N A Affara, M A Ferguson-Smith, E R Mahe. Molecular genetic analysis of the von Hippel-Lindau disease (VHL) tumour suppressor gene in gonadal tumours. European journal of cancer (Oxford, England : 1990). vol 31A. issue 13-14. 1996-08-01. PMID:8652274. |
molecular genetic analysis of the von hippel-lindau disease (vhl) tumour suppressor gene in gonadal tumours. |
1996-08-01 |
2023-08-12 |
Not clear |