| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jyun-Bin Huang, Shih-Pin Hsu, Hsiu-Yung Pan, Shang-Der Chen, Shu-Fang Chen, Tsu-Kung Lin, Xuan-Ping Liu, Jie-Hau Li, Nai-Ching Chen, Chia-Wei Liou, Chung-Yao Hsu, Hung-Yi Chuang, Yao-Chung Chuan. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33008083. |
status epilepticus may cause molecular and cellular events, leading to hippocampal neuronal cell death. |
2021-02-23 |
2023-08-13 |
rat |
| Jyun-Bin Huang, Shih-Pin Hsu, Hsiu-Yung Pan, Shang-Der Chen, Shu-Fang Chen, Tsu-Kung Lin, Xuan-Ping Liu, Jie-Hau Li, Nai-Ching Chen, Chia-Wei Liou, Chung-Yao Hsu, Hung-Yi Chuang, Yao-Chung Chuan. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33008083. |
upregulating the pgc-1α pathway will increase vegf/vegfr2 (flk-1) signaling and further activate some survival signaling that includes the mitogen activated protein kinase kinase (mek)/mitogen activated protein kinase (erk) and phosphatidylinositol 3-kinase (pi3k)/protein kinase b (akt) signaling pathways and offer neuroprotection as a consequence of apoptosis in the hippocampal neurons following status epilepticus. |
2021-02-23 |
2023-08-13 |
rat |
| Bharathi Hattiangady, Ramkumar Kuruba, Bing Shuai, Remedios Grier, Ashok K Shett. Hippocampal Neural Stem Cell Grafting after Status Epilepticus Alleviates Chronic Epilepsy and Abnormal Plasticity, and Maintains Better Memory and Mood Function. Aging and disease. vol 11. issue 6. 2021-02-15. PMID:33269095. |
hippocampal neural stem cell grafting after status epilepticus alleviates chronic epilepsy and abnormal plasticity, and maintains better memory and mood function. |
2021-02-15 |
2023-08-13 |
rat |
| Bharathi Hattiangady, Ramkumar Kuruba, Bing Shuai, Remedios Grier, Ashok K Shett. Hippocampal Neural Stem Cell Grafting after Status Epilepticus Alleviates Chronic Epilepsy and Abnormal Plasticity, and Maintains Better Memory and Mood Function. Aging and disease. vol 11. issue 6. 2021-02-15. PMID:33269095. |
hippocampal damage after status epilepticus (se) leads to multiple epileptogenic changes, which lead to chronic temporal lobe epilepsy (tle). |
2021-02-15 |
2023-08-13 |
rat |
| Ping Yuan, Wei Han, Lingling Xie, Li Cheng, Hengsheng Chen, Jin Chen, Li Jian. The implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. Cell and tissue research. vol 380. issue 3. 2021-01-28. PMID:31900663. |
the implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. |
2021-01-28 |
2023-08-13 |
rat |
| Ping Yuan, Wei Han, Lingling Xie, Li Cheng, Hengsheng Chen, Jin Chen, Li Jian. The implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. Cell and tissue research. vol 380. issue 3. 2021-01-28. PMID:31900663. |
we used the lithium-pilocarpine-induced epilepsy model in adolescent sprague-dawley rats in order to evaluate hippocampal neurogenesis and epileptogenesis following the onset of status epilepticus (se). |
2021-01-28 |
2023-08-13 |
rat |
| Jiong Yue, Chao Liang, Kefu Wu, Zhi Hou, Lukang Wang, Chunqing Zhang, Shiyong Liu, Hui Yan. Upregulated SHP-2 expression in the epileptogenic zone of temporal lobe epilepsy and various effects of SHP099 treatment on a pilocarpine model. Brain pathology (Zurich, Switzerland). vol 30. issue 2. 2021-01-13. PMID:31398269. |
in the pilocarpine-induced c57bl/6 mouse model, shp-2 upregulation in the hippocampus began one day after status epilepticus, reached a peak at 21 days and then maintained a significantly high level until day 60. |
2021-01-13 |
2023-08-13 |
mouse |
| Alberto Parras, Laura de Diego-Garcia, Mariana Alves, Edward Beamer, Giorgia Conte, Eva M Jimenez-Mateos, James Morgan, Ivana Ollà, Yasmina Hernandez-Santana, Norman Delanty, Michael A Farrell, Donncha F O'Brien, Alejandro Ocampo, David C Henshall, Raúl Méndez, José J Lucas, Tobias Enge. Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy. Brain : a journal of neurology. vol 143. issue 7. 2020-12-30. PMID:32594159. |
in the hippocampus of mice subjected to status epilepticus and epilepsy, we report >25% of the transcriptome displays changes in their poly(a) tail length, with deadenylation disproportionately affecting genes previously associated with epilepsy. |
2020-12-30 |
2023-08-13 |
mouse |
| Jae-Cheon Kim, Sun-Nyoung Hwang, Seong Yun Ki. Alteration of Gene Associated with Retinoid-interferon-induced Mortality-19-expressing Cell Types in the Mouse Hippocampus Following Pilocarpine-induced Status Epilepticus. Neuroscience. vol 425. 2020-12-15. PMID:31790668. |
alteration of gene associated with retinoid-interferon-induced mortality-19-expressing cell types in the mouse hippocampus following pilocarpine-induced status epilepticus. |
2020-12-15 |
2023-08-13 |
mouse |
| Jae-Cheon Kim, Sun-Nyoung Hwang, Seong Yun Ki. Alteration of Gene Associated with Retinoid-interferon-induced Mortality-19-expressing Cell Types in the Mouse Hippocampus Following Pilocarpine-induced Status Epilepticus. Neuroscience. vol 425. 2020-12-15. PMID:31790668. |
therefore, we investigated the expression pattern of grim-19 in the ca1 area of the hippocampus in 8-week-old male c57bl/6 mice following pilocarpine-induced status epilepticus (se). |
2020-12-15 |
2023-08-13 |
mouse |
| Ji-Eun Kim, Hana Park, Tae-Cheon Kan. CDDO-Me Distinctly Regulates Regional Specific Astroglial Responses to Status Epilepticus via ERK1/2-Nrf2, PTEN-PI3K-AKT and NFκB Signaling Pathways. Antioxidants (Basel, Switzerland). vol 9. issue 10. 2020-10-30. PMID:33096818. |
in the present study, we evaluated whether cddo-me affects astroglial responses to status epilepticus (se, a prolonged seizure activity) in the rat hippocampus in order to understand the underlying mechanisms of reactive astrogliosis and astroglial apoptosis. |
2020-10-30 |
2023-08-13 |
rat |
| Eliseo Velazco-Cercas, Luis Beltran-Parrazal, Consuelo Morgado-Valle, Maria-Leonor López-Mera. Status Epilepticus Increases Cell Proliferation and Neurogenesis in the Developing Rat Cerebellum. Cerebellum (London, England). vol 19. issue 1. 2020-10-23. PMID:31656012. |
status epilepticus (se) promotes neuronal proliferation and differentiation in the adult and developing rodent hippocampus. |
2020-10-23 |
2023-08-13 |
rat |
| Daniela M S Moura, Juliana Alves Brandão, Celia Lentini, Christophe Heinrich, Claudio M Queiroz, Marcos R Cost. Evidence of Progenitor Cell Lineage Rerouting in the Adult Mouse Hippocampus After Status Epilepticus. Frontiers in neuroscience. vol 14. 2020-10-22. PMID:33071745. |
evidence of progenitor cell lineage rerouting in the adult mouse hippocampus after status epilepticus. |
2020-10-22 |
2023-08-13 |
mouse |
| Mayara Vendramin Pasquetti, Letícia Meier, Joseane Righes Marafiga, Letícia Barbieri Caus, Adriano Bretanha Lopes Tort, Maria Elisa Calcagnott. Hippocampal CA1 and cortical interictal oscillations in the pilocarpine model of epilepsy. Brain research. vol 1722. 2020-10-21. PMID:31351038. |
animals that had status epilepticus (se) and later spontaneous recurrent seizures (srs) (epileptic animals) exhibited higher delta power recorded in cortical and hippocampal ors, rad and lm electrodes. |
2020-10-21 |
2023-08-13 |
rat |
| Hui-Ling Tang, Si-Yu Chen, Huan Zhang, Ping Lu, Wei-Wen Sun, Mei-Mei Gao, Xiang-Da Zeng, Tao Su, Yue-Sheng Lon. Expression Pattern of ALOXE3 in Mouse Brain Suggests Its Relationship with Seizure Susceptibility. Cellular and molecular neurobiology. 2020-10-15. PMID:33058074. |
in fact, decreased expression of aloxe3 and elevated concentration of aa in the hippocampus was found after status epilepticus (se) induced by pilocarpine. |
2020-10-15 |
2023-08-13 |
mouse |
| Namgue Hong, Yun-Sik Choi, Seong Yun Kim, Hee Jung Ki. Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 1. 2020-10-01. PMID:28066149. |
the muscarinic receptor agonist pilocarpine is used to induce status epilepticus, which is followed by hippocampal damage. |
2020-10-01 |
2023-08-13 |
mouse |
| Namgue Hong, Yun-Sik Choi, Seong Yun Kim, Hee Jung Ki. Neuroprotective effect of lithium after pilocarpine-induced status epilepticus in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 21. issue 1. 2020-10-01. PMID:28066149. |
the present study was designed to investigate the effects of lithium post-treatment on seizure susceptibility and hippocampal neuropathological changes following pilocarpine-induced status epilepticus. |
2020-10-01 |
2023-08-13 |
mouse |
| Ji-Eun Kim, Tae-Cheon Kan. Differential Roles of Mitochondrial Translocation of Active Caspase-3 and HMGB1 in Neuronal Death Induced by Status Epilepticus. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30233331. |
in the present study, status epilepticus (se) evoked excessive mitochondrial fission in parvalbumin (pv) cells (one of gabaergic interneurons) and abnormal mitochondrial elongation in ca1 neurons in the rat hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Peng Wu, Yue Hu, Xiu-Juan Li, Min Cheng, Li Jian. Sodium valproate suppresses abnormal neurogenesis induced by convulsive status epilepticus. Neural regeneration research. vol 14. issue 3. 2020-10-01. PMID:30539816. |
status epilepticus has been shown to activate the proliferation of neural stem cells in the hippocampus of the brain, while also causing a large amount of neuronal death, especially in the subgranular zone of the dentate gyrus and the subventricular zone. |
2020-10-01 |
2023-08-13 |
rat |
| Edward H Beamer, Jeronimo Jurado-Arjona, Eva M Jimenez-Mateos, James Morgan, Cristina R Reschke, Aidan Kenny, Gioacchino de Leo, Luis A Olivos-Oré, Marina Arribas-Blázquez, Stephen F Madden, Jesús Merchán-Rubira, Norman Delanty, Michael A Farrell, Donncha F O'Brien, Jesus Avila, Miguel Diaz-Hernandez, M Teresa Miras-Portugal, Antonio R Artalejo, Felix Hernandez, David C Henshall, Tobias Enge. MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30618601. |
prolonged seizures (status epilepticus, se) may drive hippocampal dysfunction and epileptogenesis, at least partly, through an elevation in neurogenesis, dysregulation of migration and aberrant dendritic arborization of newly-formed neurons. |
2020-10-01 |
2023-08-13 |
mouse |