| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shasha Song, Jingjiong Chen, Pinpin Xiao, Hao Duan, Yajun Zhou, Feng Wang, Hongmei Wang, Yuwu Zhao, Zhi Gen. Role of Macrophages in Status Epilepticus Predisposing to Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31796682. |
continuous epileptic seizures hallmark status epilepticus, leading to preferential neuronal cell loss in the hippocampus that can progress into alzheimer's disease. |
2021-04-19 |
2023-08-13 |
rat |
| Shasha Song, Jingjiong Chen, Pinpin Xiao, Hao Duan, Yajun Zhou, Feng Wang, Hongmei Wang, Yuwu Zhao, Zhi Gen. Role of Macrophages in Status Epilepticus Predisposing to Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31796682. |
previous studies have shown that status epilepticus prompts an overproduction of nitric oxide (no) by upregulation of no synthase ii (nos ii) to induce apoptosis of neuronal cells in the hippocampus, in a nuclear factor-kappab (nf-κb) signaling dependent manner. |
2021-04-19 |
2023-08-13 |
rat |
| Ji-Eun Kim, Hana Park, Tae-Hyun Kim, Tae-Cheon Kan. LONP1 Regulates Mitochondrial Accumulations of HMGB1 and Caspase-3 in CA1 and PV Neurons Following Status Epilepticus. International journal of molecular sciences. vol 22. issue 5. 2021-04-16. PMID:33668863. |
on the other hand, translocation of high mobility group box 1 (hmgb1) and active caspase-3 into mitochondria is involved in apoptosis of parvalbumin (pv) cells (one of the gabaergic interneurons) and necrosis of ca1 neurons in the rat hippocampus, respectively, following status epilepticus (se). |
2021-04-16 |
2023-08-13 |
rat |
| Ibrahim Devrim Gursoy, Sureyya Barun, Saban Remzi Erdem, Ulya Keskin, Murat Kiziltas, Pergin Atilla, Sevda Muftuoglu, Deniz Yuce, Firat Narin, Mert Ertunc, Yildirim Sara, Hande Canpina. Investigation of the Possible Protective Effects of Ketamine and Dantrolene on the Hippocampal Apoptosis and Spatial Learning in Rats Exposed to Repeated Electroconvulsive Seizures as a Model of Status Epilepticus. Turkish neurosurgery. vol 30. issue 6. 2021-04-05. PMID:32705669. |
investigation of the possible protective effects of ketamine and dantrolene on the hippocampal apoptosis and spatial learning in rats exposed to repeated electroconvulsive seizures as a model of status epilepticus. |
2021-04-05 |
2023-08-13 |
rat |
| Ibrahim Devrim Gursoy, Sureyya Barun, Saban Remzi Erdem, Ulya Keskin, Murat Kiziltas, Pergin Atilla, Sevda Muftuoglu, Deniz Yuce, Firat Narin, Mert Ertunc, Yildirim Sara, Hande Canpina. Investigation of the Possible Protective Effects of Ketamine and Dantrolene on the Hippocampal Apoptosis and Spatial Learning in Rats Exposed to Repeated Electroconvulsive Seizures as a Model of Status Epilepticus. Turkish neurosurgery. vol 30. issue 6. 2021-04-05. PMID:32705669. |
to evaluate the possible neuroprotective effects of ketamine and dantrolene on the hippocampal apoptosis and spatial learning in rats exposed to repeated electroconvulsive seizures (ecs) as a model of status epilepticus (se). |
2021-04-05 |
2023-08-13 |
rat |
| Samira Ramazi, Javad Fahanik-Babaei, Seyed-Mahdi Mohamadi-Zarch, Mahsa Tashakori-Miyanroudi, Davood Nourabadi, Morteza Nazari-Serenjeh, Mehrdad Roghani, Tourandokht Baluchnejadmojara. Neuroprotective and anticonvulsant effects of sinomenine in kainate rat model of temporal lobe epilepsy: Involvement of oxidative stress, inflammation and pyroptosis. Journal of chemical neuroanatomy. vol 108. 2021-04-02. PMID:32430101. |
our obtained data showed that sinomenine administration at a dose of 50 mg/kg can significantly decreases severity of seizures and incidence of status epilepticus (se), hippocampal aberrant mfs and dna fragmentation and prevents reduction of neuronal density. |
2021-04-02 |
2023-08-13 |
rat |
| Masafumi Fukud. [Diagnosing Status Epilepticus]. No shinkei geka. Neurological surgery. vol 49. issue 2. 2021-03-26. PMID:33762454. |
in status epilepticus , dwi usually depicts some hyperintense regions, such as the cerebral cortex, hippocampus, and thalamic pulvinar, where ictal brain activity and its propagation are likely occur the seizure. |
2021-03-26 |
2023-08-13 |
Not clear |
| Summya Rashid, Adil Farooq Wali, Shahzada Mudasir Rashid, Rana M Alsaffar, Ajaz Ahmad, Basit L Jan, Bilal Ahmad Paray, Saeed M A Alqahtani, Azher Arafah, Muneeb U Rehma. Zingerone Targets Status Epilepticus by Blocking Hippocampal Neurodegeneration via Regulation of Redox Imbalance, Inflammation and Apoptosis. Pharmaceuticals (Basel, Switzerland). vol 14. issue 2. 2021-03-16. PMID:33670383. |
zingerone targets status epilepticus by blocking hippocampal neurodegeneration via regulation of redox imbalance, inflammation and apoptosis. |
2021-03-16 |
2023-08-13 |
mouse |
| Xin-Li Xiao, Xiao-Lin Wu, Hua Tong, Jing Tan, Le-Fan Liu, Kai-Wei Si, Peng-Bo-Yang, Yan-Bing Ma, Jin-Song Zhou, Jian-Xin Li. Identification of microRNA-target genes in mice hippocampus at 1 week after pilocarpine-induced status epilepticus. Biochemical and biophysical research communications. vol 531. issue 3. 2021-03-10. PMID:32800559. |
identification of microrna-target genes in mice hippocampus at 1 week after pilocarpine-induced status epilepticus. |
2021-03-10 |
2023-08-13 |
mouse |
| Xin-Li Xiao, Xiao-Lin Wu, Hua Tong, Jing Tan, Le-Fan Liu, Kai-Wei Si, Peng-Bo-Yang, Yan-Bing Ma, Jin-Song Zhou, Jian-Xin Li. Identification of microRNA-target genes in mice hippocampus at 1 week after pilocarpine-induced status epilepticus. Biochemical and biophysical research communications. vol 531. issue 3. 2021-03-10. PMID:32800559. |
to investigate role of mirna in the latent stage following status epilepticus, we first compared microrna expression profiles in mice hippocampus at 1 week after pilocarpine-induced status epilepticus (se) vs. controls in hippocampal tissues using exiqon mircury lna™ mirnas array. |
2021-03-10 |
2023-08-13 |
mouse |
| Jyun-Bin Huang, Shih-Pin Hsu, Hsiu-Yung Pan, Shang-Der Chen, Shu-Fang Chen, Tsu-Kung Lin, Xuan-Ping Liu, Jie-Hau Li, Nai-Ching Chen, Chia-Wei Liou, Chung-Yao Hsu, Hung-Yi Chuang, Yao-Chung Chuan. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33008083. |
status epilepticus may cause molecular and cellular events, leading to hippocampal neuronal cell death. |
2021-02-23 |
2023-08-13 |
rat |
| Jyun-Bin Huang, Shih-Pin Hsu, Hsiu-Yung Pan, Shang-Der Chen, Shu-Fang Chen, Tsu-Kung Lin, Xuan-Ping Liu, Jie-Hau Li, Nai-Ching Chen, Chia-Wei Liou, Chung-Yao Hsu, Hung-Yi Chuang, Yao-Chung Chuan. Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33008083. |
upregulating the pgc-1α pathway will increase vegf/vegfr2 (flk-1) signaling and further activate some survival signaling that includes the mitogen activated protein kinase kinase (mek)/mitogen activated protein kinase (erk) and phosphatidylinositol 3-kinase (pi3k)/protein kinase b (akt) signaling pathways and offer neuroprotection as a consequence of apoptosis in the hippocampal neurons following status epilepticus. |
2021-02-23 |
2023-08-13 |
rat |
| Bharathi Hattiangady, Ramkumar Kuruba, Bing Shuai, Remedios Grier, Ashok K Shett. Hippocampal Neural Stem Cell Grafting after Status Epilepticus Alleviates Chronic Epilepsy and Abnormal Plasticity, and Maintains Better Memory and Mood Function. Aging and disease. vol 11. issue 6. 2021-02-15. PMID:33269095. |
hippocampal neural stem cell grafting after status epilepticus alleviates chronic epilepsy and abnormal plasticity, and maintains better memory and mood function. |
2021-02-15 |
2023-08-13 |
rat |
| Bharathi Hattiangady, Ramkumar Kuruba, Bing Shuai, Remedios Grier, Ashok K Shett. Hippocampal Neural Stem Cell Grafting after Status Epilepticus Alleviates Chronic Epilepsy and Abnormal Plasticity, and Maintains Better Memory and Mood Function. Aging and disease. vol 11. issue 6. 2021-02-15. PMID:33269095. |
hippocampal damage after status epilepticus (se) leads to multiple epileptogenic changes, which lead to chronic temporal lobe epilepsy (tle). |
2021-02-15 |
2023-08-13 |
rat |
| Ping Yuan, Wei Han, Lingling Xie, Li Cheng, Hengsheng Chen, Jin Chen, Li Jian. The implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. Cell and tissue research. vol 380. issue 3. 2021-01-28. PMID:31900663. |
the implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. |
2021-01-28 |
2023-08-13 |
rat |
| Ping Yuan, Wei Han, Lingling Xie, Li Cheng, Hengsheng Chen, Jin Chen, Li Jian. The implications of hippocampal neurogenesis in adolescent rats after status epilepticus: a novel role of notch signaling pathway in regulating epileptogenesis. Cell and tissue research. vol 380. issue 3. 2021-01-28. PMID:31900663. |
we used the lithium-pilocarpine-induced epilepsy model in adolescent sprague-dawley rats in order to evaluate hippocampal neurogenesis and epileptogenesis following the onset of status epilepticus (se). |
2021-01-28 |
2023-08-13 |
rat |
| Jiong Yue, Chao Liang, Kefu Wu, Zhi Hou, Lukang Wang, Chunqing Zhang, Shiyong Liu, Hui Yan. Upregulated SHP-2 expression in the epileptogenic zone of temporal lobe epilepsy and various effects of SHP099 treatment on a pilocarpine model. Brain pathology (Zurich, Switzerland). vol 30. issue 2. 2021-01-13. PMID:31398269. |
in the pilocarpine-induced c57bl/6 mouse model, shp-2 upregulation in the hippocampus began one day after status epilepticus, reached a peak at 21 days and then maintained a significantly high level until day 60. |
2021-01-13 |
2023-08-13 |
mouse |
| Alberto Parras, Laura de Diego-Garcia, Mariana Alves, Edward Beamer, Giorgia Conte, Eva M Jimenez-Mateos, James Morgan, Ivana Ollà, Yasmina Hernandez-Santana, Norman Delanty, Michael A Farrell, Donncha F O'Brien, Alejandro Ocampo, David C Henshall, Raúl Méndez, José J Lucas, Tobias Enge. Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy. Brain : a journal of neurology. vol 143. issue 7. 2020-12-30. PMID:32594159. |
in the hippocampus of mice subjected to status epilepticus and epilepsy, we report >25% of the transcriptome displays changes in their poly(a) tail length, with deadenylation disproportionately affecting genes previously associated with epilepsy. |
2020-12-30 |
2023-08-13 |
mouse |
| Jae-Cheon Kim, Sun-Nyoung Hwang, Seong Yun Ki. Alteration of Gene Associated with Retinoid-interferon-induced Mortality-19-expressing Cell Types in the Mouse Hippocampus Following Pilocarpine-induced Status Epilepticus. Neuroscience. vol 425. 2020-12-15. PMID:31790668. |
alteration of gene associated with retinoid-interferon-induced mortality-19-expressing cell types in the mouse hippocampus following pilocarpine-induced status epilepticus. |
2020-12-15 |
2023-08-13 |
mouse |
| Jae-Cheon Kim, Sun-Nyoung Hwang, Seong Yun Ki. Alteration of Gene Associated with Retinoid-interferon-induced Mortality-19-expressing Cell Types in the Mouse Hippocampus Following Pilocarpine-induced Status Epilepticus. Neuroscience. vol 425. 2020-12-15. PMID:31790668. |
therefore, we investigated the expression pattern of grim-19 in the ca1 area of the hippocampus in 8-week-old male c57bl/6 mice following pilocarpine-induced status epilepticus (se). |
2020-12-15 |
2023-08-13 |
mouse |