| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiahang Sun, Xiaoying Gao, Dawei Meng, Yang Xu, Xichun Wang, Xin Gu, Mian Guo, Xiaodong Shao, Hongwen Yan, Chuanlu Jiang, Yongri Zhen. Antagomirs Targeting MiroRNA-134 Attenuates Epilepsy in Rats through Regulation of Oxidative Stress, Mitochondrial Functions and Autophagy. Frontiers in pharmacology. vol 8. 2020-09-29. PMID:28848439. |
the ant-134 treatment also significantly increased the production of atp and the activities of mitochondrial respiratory enzyme complexes and significantly decreased the reactive oxygen species generation in the hippocampus compared with the status epilepticus rats. |
2020-09-29 |
2023-08-13 |
rat |
| Gabriela G Regner, Patrícia Pereira, Douglas T Leffa, Carla de Oliveira, Rafael Vercelino, Felipe Fregni, Iraci L S Torre. Preclinical to Clinical Translation of Studies of Transcranial Direct-Current Stimulation in the Treatment of Epilepsy: A Systematic Review. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:29623027. |
we found that few preclinical findings have been translated into clinical research (number of sessions and effects on seizure frequency) and that most findings have not been tested clinically (effects of tdcs on status epilepticus and absence epilepsy, neuroprotective effects in the hippocampus, and combined use with specific medications). |
2020-09-29 |
2023-08-13 |
Not clear |
| Dong-Qi Lin, Xin-Ying Cai, Chun-Hua Wang, Bin Yang, Ri-Sheng Lian. Optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus. Neural regeneration research. vol 15. issue 5. 2020-09-28. PMID:31719260. |
optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus. |
2020-09-28 |
2023-08-13 |
mouse |
| Dong-Qi Lin, Xin-Ying Cai, Chun-Hua Wang, Bin Yang, Ri-Sheng Lian. Optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus. Neural regeneration research. vol 15. issue 5. 2020-09-28. PMID:31719260. |
hippocampal neurons undergo various forms of cell death after status epilepticus. |
2020-09-28 |
2023-08-13 |
mouse |
| Dong-Qi Lin, Xin-Ying Cai, Chun-Hua Wang, Bin Yang, Ri-Sheng Lian. Optimal concentration of necrostatin-1 for protecting against hippocampal neuronal damage in mice with status epilepticus. Neural regeneration research. vol 15. issue 5. 2020-09-28. PMID:31719260. |
therefore, in this study, we investigated the effects of necrostatin-1 on hippocampal neurons in mice with status epilepticus, and, furthermore, we tested different amounts of the compound to identify the optimal concentration for inhibiting necroptosis and apoptosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Aasia Batool, Thomas D M Hill, Ngoc T Nguyen, Elena Langa, Mairéad Diviney, Catherine Mooney, Gary P Brennan, Niamh M C Connolly, Amaya Sanz-Rodriguez, Brenton L Cavanagh, David C Henshal. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32009885. |
altered biogenesis and microrna content of hippocampal exosomes following experimental status epilepticus. |
2020-09-28 |
2023-08-13 |
mouse |
| Aasia Batool, Thomas D M Hill, Ngoc T Nguyen, Elena Langa, Mairéad Diviney, Catherine Mooney, Gary P Brennan, Niamh M C Connolly, Amaya Sanz-Rodriguez, Brenton L Cavanagh, David C Henshal. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32009885. |
repetitive or prolonged seizures (status epilepticus) can damage neurons within the hippocampus, trigger gliosis, and generate an enduring state of hyperexcitability. |
2020-09-28 |
2023-08-13 |
mouse |
| Aasia Batool, Thomas D M Hill, Ngoc T Nguyen, Elena Langa, Mairéad Diviney, Catherine Mooney, Gary P Brennan, Niamh M C Connolly, Amaya Sanz-Rodriguez, Brenton L Cavanagh, David C Henshal. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32009885. |
status epilepticus induced by unilateral intra-amygdala kainic acid in mice resulted in acute subfield-specific, bi-directional changes in hippocampal transcripts associated with exosome biosynthesis including up-regulation of endosomal sorting complexes required for transport (escrt)-dependent and -independent pathways. |
2020-09-28 |
2023-08-13 |
mouse |
| Aasia Batool, Thomas D M Hill, Ngoc T Nguyen, Elena Langa, Mairéad Diviney, Catherine Mooney, Gary P Brennan, Niamh M C Connolly, Amaya Sanz-Rodriguez, Brenton L Cavanagh, David C Henshal. Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus. Frontiers in neuroscience. vol 13. 2020-09-28. PMID:32009885. |
increased expression of exosome components including alix were detectable in samples obtained 2 weeks after status epilepticus and changes occurred in both the ipsilateral and contralateral hippocampus. |
2020-09-28 |
2023-08-13 |
mouse |
| Yan Chen, Zhiwei Feng, Mingzhe Shen, Weiwei Lin, Yuanqiang Wang, Siyi Wang, Caifeng Li, Shengfeng Wang, Maozi Chen, Weiguang Shan, Xiang-Qun Xi. Insight into ACS omega. vol 5. issue 5. 2020-09-28. PMID:32064403. |
interestingly, recent studies suggest that the occurrence of a reciprocal involvement of 5-ht receptor activation along with the hippocampal bdnf-increased expression can significantly ameliorate neurologic changes and reverse behavioral deficits in status epilepticus rats while improving cognitive function and alleviating neuronal injury. |
2020-09-28 |
2023-08-13 |
rat |
| Ying Yu, Jianxiong Jian. COX-2/PGE Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913950. |
cox-2/pge the objective of this study was to identify the signaling pathway that is immediately triggered by status epilepticus (se) and in turn contributes to the excessive brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase receptor b (trkb) signaling within the hippocampus. |
2020-09-28 |
2023-08-13 |
Not clear |
| Shi Yu, Hujing Zhang, Yue Hei, Xicai Yi, Andrius Baskys, Weiping Liu, Qianfa Lon. High mobility group box-1 (HMGB1) antagonist BoxA suppresses status epilepticus-induced neuroinflammatory responses associated with Toll-like receptor 2/4 down-regulation in rats. Brain research. vol 1717. 2020-09-24. PMID:30986405. |
blood-brain barrier (bbb) permeability, brain water content, hippocampal neuroinflammation and neuronal apoptosis were measured 24 h after the pilocarpine induction of status epilepticus (se) in sprague-dawley rats treated with boxa. |
2020-09-24 |
2023-08-13 |
rat |
| Dong-Hoon Lee, Do-Wan Lee, Jae-Im Kwon, Sang-Tae Kim, Chul-Woong Woo, Jeong Kon Kim, Kyung Won Kim, Jin Seong Lee, Choong Gon Choi, Ji-Yeon Suh, Yoonseok Choi, Dong-Cheol Wo. Changes to gamma-aminobutyric acid levels during short-term epileptiform activity in a kainic acid-induced rat model of status epilepticus: A chemical exchange saturation transfer imaging study. Brain research. vol 1717. 2020-09-24. PMID:30991042. |
to evaluate temporal changes in gamma-aminobutyric acid (gaba) signals in the hippocampus during epileptiform activity induced by kainic acid (ka) in a rat model of status epilepticus using chemical exchange saturation transfer (cest) imaging technique. |
2020-09-24 |
2023-08-13 |
rat |
| Fabio Gualtieri, Marta Nowakowska, Eva-Lotta von Rüden, Isabel Seiffert, Heidrun Potschk. Epileptogenesis-Associated Alterations of Heat Shock Protein 70 in a Rat Post-Status Epilepticus Model. Neuroscience. vol 415. 2020-09-23. PMID:31319099. |
thus, we investigated immunohistochemical expression of hsp70 in hippocampus, parahippocampal cortex, parietal cortex, amygdala, and thalamus following status epilepticus in a rat model of temporal lobe epilepsy. |
2020-09-23 |
2023-08-13 |
rat |
| Aihua Wang, Zhihua Si, Ping Xue, Xiaolin Li, Jinzhi Li. Tacrolimus protects hippocampal neurons of rats with status epilepticus through suppressing oxidative stress and inhibiting mitochondrial pathway of apoptosis. Brain research. vol 1715. 2020-09-18. PMID:30831086. |
tacrolimus protects hippocampal neurons of rats with status epilepticus through suppressing oxidative stress and inhibiting mitochondrial pathway of apoptosis. |
2020-09-18 |
2023-08-13 |
rat |
| Aihua Wang, Zhihua Si, Ping Xue, Xiaolin Li, Jinzhi Li. Tacrolimus protects hippocampal neurons of rats with status epilepticus through suppressing oxidative stress and inhibiting mitochondrial pathway of apoptosis. Brain research. vol 1715. 2020-09-18. PMID:30831086. |
to investigate the mechanisms underlying the neuroprotective effect of tacrolimus (fk506) on the hippocampal neurons of rats with status epilepticus (se). |
2020-09-18 |
2023-08-13 |
rat |
| Sebastian Meller, Claudia Brandt, Wiebke Theilmann, Jochen Klein, Wolfgang Lösche. Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy. Brain research. vol 1712. 2020-09-11. PMID:30703372. |
commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy. |
2020-09-11 |
2023-08-13 |
rat |
| Qiong Wu, Miao Zhang, Xueyan Liu, Junmei Zhang, Hua Wan. CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus. International journal of molecular medicine. vol 45. issue 2. 2020-09-11. PMID:31894322. |
cb2r orchestrates neuronal autophagy through regulation of the mtor signaling pathway in the hippocampus of developing rats with status epilepticus. |
2020-09-11 |
2023-08-13 |
rat |
| Xinjian Zhu, Aifeng Zhang, Jingde Dong, Yuanyuan Yao, Mengyi Zhu, Kangni Xu, Mohammed Hidayath Al Hamd. MicroRNA-23a contributes to hippocampal neuronal injuries and spatial memory impairment in an experimental model of temporal lobe epilepsy. Brain research bulletin. vol 152. 2020-08-14. PMID:31336125. |
we found that mir-23a is upregulated in the hippocampus after status epilepticus (se) in kanic acid (ka)-induced tle mice. |
2020-08-14 |
2023-08-13 |
mouse |
| Edward Beamer, Giorgia Conte, Tobias Enge. ATP release during seizures - A critical evaluation of the evidence. Brain research bulletin. vol 151. 2020-08-04. PMID:30660718. |
two studies using microdialysis found no change in extracellular atp in the hippocampus of rats during experimentally-induced status epilepticus. |
2020-08-04 |
2023-08-13 |
rat |