| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingqin Tan, Zhenzhen Tu, Wei Han, Xiaojie Song, Li Cheng, Hengsheng Chen, Shengfen Tu, Pan Li, Wei Liu, Li Jian. Anticonvulsant and Neuroprotective Effects of Dexmedetomidine on Pilocarpine-Induced Status Epilepticus in Rats Using a Metabolomics Approach. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-08-26. PMID:30892279. |
results results of metabolic profiles of the hippocampus tissues of rats proved that dexmedetomidine relieved rats suffering from the status epilepticus by restoring the damaged neuromodulatory metabolism and neurotransmitters, reducing the disturbance in energy, improving oxidative stress, and alleviating nucleic acid metabolism and amino acid in pilocarpine-induced status epilepticus rats. |
2019-08-26 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
resveratrol promotes mitochondrial biogenesis and protects against seizure-induced neuronal cell damage in the hippocampus following status epilepticus by activation of the pgc-1α signaling pathway. |
2019-07-17 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
this study examined the neuroprotective effect of resveratrol on mitochondrial biogenesis in the hippocampus following experimental status epilepticus. |
2019-07-17 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
in addition, resveratrol reduced activated caspase-3 activity and attenuated neuronal cell damage in the hippocampus following status epilepticus. |
2019-07-17 |
2023-08-13 |
rat |
| Federica Frigerio, Giulia Pasqualini, Ilaria Craparotta, Sergio Marchini, Erwin A van Vliet, Patrick Foerch, Catherine Vandenplas, Karin Leclercq, Eleonora Aronica, Luca Porcu, Kimberly Pistorius, Romain A Colas, Trond V Hansen, Mauro Perretti, Rafal M Kaminski, Jesmond Dalli, Annamaria Vezzan. n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain : a journal of neurology. vol 141. issue 11. 2019-07-15. PMID:30307467. |
these receptors were also induced in the human hippocampus after status epilepticus and in patients with temporal lobe epilepsy. |
2019-07-15 |
2023-08-13 |
mouse |
| Marharyta Semenikhina, Ruslan Bogovyk, Mykhailo Fedoriuk, Oksana Nikolaienko, Lina T Al Kury, Alina Savotchenko, Oleg Krishtal, Elena Isaev. Inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus. Neuroscience letters. vol 692. 2019-06-21. PMID:30391321. |
inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus. |
2019-06-21 |
2023-08-13 |
rat |
| Zhi Huang, Yajun Lian, Yuan Chen, Shuang Li, Haifeng Zhang, Nanchang Xie, Yake Zheng, Shouyi Wu, Yuhan Wang, Wenchao Cheng, Qiaoman Zhang, Chengze Wang, Yinping Shi, Na Xi. Intranasal Delivery of Botulinum Neurotoxin A Protects against Hippocampal Neuron Death in the Lithium-Pilocarpine Rat Model. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30877518. |
to assess whether intranasal administration is feasible, we examined the role of botulinum neurotoxin a (bont/a) in hippocampal neuronal injury after status epilepticus (se) induced by pilocarpine. |
2019-06-11 |
2023-08-13 |
rat |
| Qiong Wu, Hua Wan. The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. Epilepsy research. vol 148. 2019-05-30. PMID:30317115. |
the spatiotemporal expression changes of cb2r in the hippocampus of rats following pilocarpine-induced status epilepticus. |
2019-05-30 |
2023-08-13 |
rat |
| Qiong Wu, Hua Wan. The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. Epilepsy research. vol 148. 2019-05-30. PMID:30317115. |
to investigate the spatiotemporal expression of cannabinoid receptor type 2 (cb2r) in the hippocampus of pilocarpine-treated rats experiencing a status epilepticus (se). |
2019-05-30 |
2023-08-13 |
rat |
| Jie Hua Xu, Hui Wang, Wen Zhang, Feng Ru Tan. Alterations of L-type voltage dependent calcium channel alpha 1 subunit in the hippocampal CA3 region during and after pilocarpine-induced epilepsy. Neurochemistry international. vol 114. 2019-05-08. PMID:29425964. |
in the present study in the mouse pilocarpine model of temporal lobe epilepsy, we investigated the alterations of alpha 1 subunits of l-type vdcc in the ca3 area of the hippocampus at different stages of epileptogenesis, i.e., acute stage from 10 min to 1 day during and after pilocapine-induced status epilepticus (se), latent period at 1 week, and chronic stage with spontaneous recurrent seizures at 2 months after se. |
2019-05-08 |
2023-08-13 |
mouse |
| Tatyana Y Postnikova, Alina M Trofimova, Julia L Ergina, Olga E Zubareva, Sergey V Kalemenev, Aleksey V Zaitse. Transient Switching of NMDA-Dependent Long-Term Synaptic Potentiation in CA3-CA1 Hippocampal Synapses to mGluR Cellular and molecular neurobiology. vol 39. issue 2. 2019-04-29. PMID:30607810. |
transient switching of nmda-dependent long-term synaptic potentiation in ca3-ca1 hippocampal synapses to mglur the mechanisms of impairment in long-term potentiation after status epilepticus (se) remain unclear. |
2019-04-29 |
2023-08-13 |
rat |
| Li-Gang Huang, Jing Zou, Qin-Chi L. Silencing rno-miR-155-5p in rat temporal lobe epilepsy model reduces pathophysiological features and cell apoptosis by activating Sestrin-3. Brain research. vol 1689. 2019-04-17. PMID:29191771. |
importantly, injection of an antagomir of rno-mir-155-5p in vivo resulted in a reduction of the pathophysiological features associated with the status epilepticus, which was accompanied by decrease of apoptosis in the hippocampus. |
2019-04-17 |
2023-08-13 |
rat |
| Nikita Nirwan, Fouzia Siraj, Divya Vohor. Inverted-U response of lacosamide on pilocarpine-induced status epilepticus and oxidative stress in C57BL/6 mice is independent of hippocampal collapsin response mediator protein-2. Epilepsy research. vol 145. 2019-04-05. PMID:29935443. |
inverted-u response of lacosamide on pilocarpine-induced status epilepticus and oxidative stress in c57bl/6 mice is independent of hippocampal collapsin response mediator protein-2. |
2019-04-05 |
2023-08-13 |
mouse |
| Chun-Lei Han, Xue-Min Zhao, Yun-Peng Liu, Kai-Liang Wang, Ning Chen, Wei Hu, Jian-Guo Zhang, Ming Ge, Fan-Gang Men. Gene Expression Profiling of Two Epilepsy Models Reveals the ECM/Integrin signaling Pathway is Involved in Epiletogenesis. Neuroscience. vol 396. 2019-04-01. PMID:30452975. |
this study may provide a "gene/pathway database" that with further investigation can determine the mechanisms underlining epileptogenesis and the possible targets for neuron protection in the hippocampus after status epilepticus. |
2019-04-01 |
2023-08-13 |
mouse |
| Dinesh Upadhya, Bharathi Hattiangady, Olagide W Castro, Bing Shuai, Maheedhar Kodali, Sahithi Attaluri, Adrian Bates, Yi Dong, Su-Chun Zhang, Darwin J Prockop, Ashok K Shett. Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 1. 2019-03-18. PMID:30559206. |
through comprehensive video- electroencephalographic recordings and a battery of behavioral tests in a rat model, we demonstrate that grafting of hipsc-derived mge-like interneuron precursors into the hippocampus after status epilepticus (se) greatly restrained srs and alleviated cognitive, memory, and mood dysfunction in the chronic phase of tle. |
2019-03-18 |
2023-08-13 |
human |
| Jin-Tao Liu, Sheng-Xi Wu, Hua Zhang, Fang Kuan. Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 15. issue 4. 2019-03-12. PMID:30112701. |
inhibition of myd88 signaling skews microglia/macrophage polarization and attenuates neuronal apoptosis in the hippocampus after status epilepticus in mice. |
2019-03-12 |
2023-08-13 |
mouse |
| Tatyana Y Postnikova, Dmitry V Amakhin, Alina M Trofimova, Ilya V Smolensky, Aleksey V Zaitse. Changes in Functional Properties of Rat Hippocampal Neurons Following Pentylenetetrazole-induced Status Epilepticus. Neuroscience. vol 399. 2019-03-11. PMID:30593922. |
changes in functional properties of rat hippocampal neurons following pentylenetetrazole-induced status epilepticus. |
2019-03-11 |
2023-08-13 |
rat |
| Kah Ni Tan, David Simmons, Catalina Carrasco-Pozo, Karin Borge. Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration. Journal of neurochemistry. vol 144. issue 4. 2019-03-08. PMID:29222946. |
here, we investigated the effects of triheptanoin against changes of hippocampal mitochondrial functions, oxidative stress and cell death induced by pilocarpine-induced status epilepticus (se) in mice. |
2019-03-08 |
2023-08-13 |
mouse |
| Erkut Baha Bulduk, Gokhan Kurt, Sureyya Barun, Onder Aydemir, Murat Kiziltas, Murat Oktem, Turan Turhan, Pergin Atilla, Sevda Muftuogl. The Effects of Minocycline on the Hippocampus in Lithium- Pilocarpine Induced Status Epilepticus in Rat: Relations with Microglial/Astrocytic Activation and Serum S100B Level. Turkish neurosurgery. vol 29. issue 1. 2019-02-27. PMID:30614506. |
the effects of minocycline on the hippocampus in lithium- pilocarpine induced status epilepticus in rat: relations with microglial/astrocytic activation and serum s100b level. |
2019-02-27 |
2023-08-13 |
rat |
| Dinesh Upadhya, Olagide W Castro, Raghavendra Upadhya, Ashok K Shett. Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29372545. |
the hippocampus is one of the most susceptible regions in the brain to be distraught with status epilepticus (se) induced injury. |
2019-02-26 |
2023-08-13 |
Not clear |