| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Engel, Raquel Gómez-Sintes, Mariana Alves, Eva M Jimenez-Mateos, Marta Fernández-Nogales, Amaya Sanz-Rodriguez, James Morgan, Edward Beamer, Alberto Rodríguez-Matellán, Mark Dunleavy, Takanori Sano, Jesus Avila, Miguel Medina, Felix Hernandez, José J Lucas, David C Henshal. Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus. Cell death & disease. vol 9. issue 10. 2019-11-25. PMID:30237424. |
bi-directional genetic modulation of gsk-3β exacerbates hippocampal neuropathology in experimental status epilepticus. |
2019-11-25 |
2023-08-13 |
mouse |
| Tobias Engel, Raquel Gómez-Sintes, Mariana Alves, Eva M Jimenez-Mateos, Marta Fernández-Nogales, Amaya Sanz-Rodriguez, James Morgan, Edward Beamer, Alberto Rodríguez-Matellán, Mark Dunleavy, Takanori Sano, Jesus Avila, Miguel Medina, Felix Hernandez, José J Lucas, David C Henshal. Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus. Cell death & disease. vol 9. issue 10. 2019-11-25. PMID:30237424. |
status epilepticus resulted in a spatiotemporal regulation of gsk-3 expression and activity in the hippocampus, with decreased gsk-3 activity evident in non-damaged hippocampal areas. |
2019-11-25 |
2023-08-13 |
mouse |
| Tobias Engel, Raquel Gómez-Sintes, Mariana Alves, Eva M Jimenez-Mateos, Marta Fernández-Nogales, Amaya Sanz-Rodriguez, James Morgan, Edward Beamer, Alberto Rodríguez-Matellán, Mark Dunleavy, Takanori Sano, Jesus Avila, Miguel Medina, Felix Hernandez, José J Lucas, David C Henshal. Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus. Cell death & disease. vol 9. issue 10. 2019-11-25. PMID:30237424. |
surprisingly, decreasing gsk-3 activity, either via overexpression of gsk-3β-dn or through the use of specific gsk-3 inhibitors, also exacerbated hippocampal damage and increased seizure severity during status epilepticus. |
2019-11-25 |
2023-08-13 |
mouse |
| Hiram Luna-Munguia, Alexander G Zestos, Stephen V Gliske, Robert T Kennedy, William C Stace. Chemical biomarkers of epileptogenesis and ictogenesis in experimental epilepsy. Neurobiology of disease. vol 121. 2019-11-21. PMID:30304705. |
using serial hippocampal microdialysis collections starting two weeks after the pilocarpine-induced status epilepticus, we evaluated how this chronic epilepsy model affects molecule levels and their interactions. |
2019-11-21 |
2023-08-13 |
rat |
| Jinzhi Liu, Xiaolin Li, Liguang Chen, Ping Xue, Qianqian Yang, Aihua Wan. Increased calcineurin expression after pilocarpine-induced status epilepticus is associated with brain focal edema and astrogliosis. The International journal of neuroscience. vol 126. issue 6. 2019-11-20. PMID:26000933. |
in this study, we employed a model of lithium-pilocarpine-induced status epilepticus and detected calcineurin expression in hippocampus by immunoblotting, brain focal edema by non-invasive magnetic resonance imaging (mri-7t) and astrocyte expression by immunohistochemistry. |
2019-11-20 |
2023-08-13 |
Not clear |
| Rohan Jagirdar, Meinrad Drexel, Anneliese Bukovac, Ramon O Tasan, Günther Sper. Expression of class II histone deacetylases in two mouse models of temporal lobe epilepsy. Journal of neurochemistry. vol 136. issue 4. 2019-11-20. PMID:26603269. |
beyond this, striking similarities between both temporal lobe epilepsy models such as fast decreases in hdac7 and 10 mrnas during the acute status epilepticus were observed, notably also in the contralateral hippocampus not affected by neurodegeneration. |
2019-11-20 |
2023-08-13 |
mouse |
| Xiaodong Cai, Ling Long, Libai Yang, Ziyi Chen, Guanzhong Ni, Jiaming Qin, Jueqian Zhou, Liemin Zho. Association between mossy fiber sprouting and expression of semaphorin-3f protein in dentate gyrus of hippocampus in lithium-pilocarpine-induced status epilepticus mouse model. Neurological research. vol 38. issue 11. 2019-11-20. PMID:27745527. |
association between mossy fiber sprouting and expression of semaphorin-3f protein in dentate gyrus of hippocampus in lithium-pilocarpine-induced status epilepticus mouse model. |
2019-11-20 |
2023-08-13 |
mouse |
| Tao-Ran Li, Yan-Jie Jia, Qun Wang, Xiao-Qiu Shao, Ping Zhang, Rui-Juan L. Correlation between tumor necrosis factor alpha mRNA and microRNA-155 expression in rat models and patients with temporal lobe epilepsy. Brain research. vol 1700. 2019-09-27. PMID:30006293. |
we performed real-time quantitative pcr (qrt-pcr) on the rat hippocampus 2 h, 7 days, 21 days and 60 days following kainic acid-induced status epilepticus (se) and on hippocampi obtained from tle patients and normal controls. |
2019-09-27 |
2023-08-13 |
rat |
| César Emmanuel Santana-Gómez, María Guadalupe Valle-Dorado, Ana Esmeralda Domínguez-Valentín, Arely Hernández-Moreno, Sandra Orozco-Suárez, Luisa Roch. Neuroprotective effects of levetiracetam, both alone and combined with propylparaben, in the long-term consequences induced by lithium-pilocarpine status epilepticus. Neurochemistry international. vol 120. 2019-09-17. PMID:30213635. |
status epilepticus (se) is a neurological condition that frequently induces severe neuronal injury in the hippocampus, subsequent epileptogenesis and pharmacoresistant spontaneous recurrent seizures (srs). |
2019-09-17 |
2023-08-13 |
Not clear |
| X L Wu, J S Zhou, L H Wang, J X Liu, H B Hu, X T Zhang, Y J Li, F R Tan. Proliferation of NG2 cells in the epileptic hippocampus. Epilepsy research. vol 152. 2019-08-27. PMID:30909054. |
in the present study, the expression of ng2 was investigated in the mouse hippocampus after pilocarpine-induced status epilepticus (pise). |
2019-08-27 |
2023-08-13 |
mouse |
| Xingqin Tan, Zhenzhen Tu, Wei Han, Xiaojie Song, Li Cheng, Hengsheng Chen, Shengfen Tu, Pan Li, Wei Liu, Li Jian. Anticonvulsant and Neuroprotective Effects of Dexmedetomidine on Pilocarpine-Induced Status Epilepticus in Rats Using a Metabolomics Approach. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-08-26. PMID:30892279. |
results results of metabolic profiles of the hippocampus tissues of rats proved that dexmedetomidine relieved rats suffering from the status epilepticus by restoring the damaged neuromodulatory metabolism and neurotransmitters, reducing the disturbance in energy, improving oxidative stress, and alleviating nucleic acid metabolism and amino acid in pilocarpine-induced status epilepticus rats. |
2019-08-26 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
resveratrol promotes mitochondrial biogenesis and protects against seizure-induced neuronal cell damage in the hippocampus following status epilepticus by activation of the pgc-1α signaling pathway. |
2019-07-17 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
this study examined the neuroprotective effect of resveratrol on mitochondrial biogenesis in the hippocampus following experimental status epilepticus. |
2019-07-17 |
2023-08-13 |
rat |
| Yao-Chung Chuang, Shang-Der Chen, Chung-Yao Hsu, Shu-Fang Chen, Nai-Ching Chen, Shuo-Bin Jo. Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1α Signaling Pathway. International journal of molecular sciences. vol 20. issue 4. 2019-07-17. PMID:30823590. |
in addition, resveratrol reduced activated caspase-3 activity and attenuated neuronal cell damage in the hippocampus following status epilepticus. |
2019-07-17 |
2023-08-13 |
rat |
| Federica Frigerio, Giulia Pasqualini, Ilaria Craparotta, Sergio Marchini, Erwin A van Vliet, Patrick Foerch, Catherine Vandenplas, Karin Leclercq, Eleonora Aronica, Luca Porcu, Kimberly Pistorius, Romain A Colas, Trond V Hansen, Mauro Perretti, Rafal M Kaminski, Jesmond Dalli, Annamaria Vezzan. n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis. Brain : a journal of neurology. vol 141. issue 11. 2019-07-15. PMID:30307467. |
these receptors were also induced in the human hippocampus after status epilepticus and in patients with temporal lobe epilepsy. |
2019-07-15 |
2023-08-13 |
mouse |
| Marharyta Semenikhina, Ruslan Bogovyk, Mykhailo Fedoriuk, Oksana Nikolaienko, Lina T Al Kury, Alina Savotchenko, Oleg Krishtal, Elena Isaev. Inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus. Neuroscience letters. vol 692. 2019-06-21. PMID:30391321. |
inhibition of protease-activated receptor 1 ameliorates behavioral deficits and restores hippocampal synaptic plasticity in a rat model of status epilepticus. |
2019-06-21 |
2023-08-13 |
rat |
| Zhi Huang, Yajun Lian, Yuan Chen, Shuang Li, Haifeng Zhang, Nanchang Xie, Yake Zheng, Shouyi Wu, Yuhan Wang, Wenchao Cheng, Qiaoman Zhang, Chengze Wang, Yinping Shi, Na Xi. Intranasal Delivery of Botulinum Neurotoxin A Protects against Hippocampal Neuron Death in the Lithium-Pilocarpine Rat Model. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30877518. |
to assess whether intranasal administration is feasible, we examined the role of botulinum neurotoxin a (bont/a) in hippocampal neuronal injury after status epilepticus (se) induced by pilocarpine. |
2019-06-11 |
2023-08-13 |
rat |
| Qiong Wu, Hua Wan. The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. Epilepsy research. vol 148. 2019-05-30. PMID:30317115. |
the spatiotemporal expression changes of cb2r in the hippocampus of rats following pilocarpine-induced status epilepticus. |
2019-05-30 |
2023-08-13 |
rat |
| Qiong Wu, Hua Wan. The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus. Epilepsy research. vol 148. 2019-05-30. PMID:30317115. |
to investigate the spatiotemporal expression of cannabinoid receptor type 2 (cb2r) in the hippocampus of pilocarpine-treated rats experiencing a status epilepticus (se). |
2019-05-30 |
2023-08-13 |
rat |
| Jie Hua Xu, Hui Wang, Wen Zhang, Feng Ru Tan. Alterations of L-type voltage dependent calcium channel alpha 1 subunit in the hippocampal CA3 region during and after pilocarpine-induced epilepsy. Neurochemistry international. vol 114. 2019-05-08. PMID:29425964. |
in the present study in the mouse pilocarpine model of temporal lobe epilepsy, we investigated the alterations of alpha 1 subunits of l-type vdcc in the ca3 area of the hippocampus at different stages of epileptogenesis, i.e., acute stage from 10 min to 1 day during and after pilocapine-induced status epilepticus (se), latent period at 1 week, and chronic stage with spontaneous recurrent seizures at 2 months after se. |
2019-05-08 |
2023-08-13 |
mouse |