| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Engel, David C Henshal. Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? International journal of physiology, pathophysiology and pharmacology. vol 1. issue 2. 2021-10-20. PMID:21383882. |
molecular pathways underlying neuronal death are of importance because prolonged seizure episodes (status epilepticus) cause significant damage to the brain, particularly within vulnerable structures such as the hippocampus. |
2021-10-20 |
2023-08-12 |
Not clear |
| Igor Santana de Melo, Yngrid Mickaelli Oliveira Dos Santos, Amanda Larissa Dias Pacheco, Maisa Araújo Costa, Vanessa de Oliveira Silva, Jucilene Freitas-Santos, Cibelle de Melo Bastos Cavalcante, Reginaldo Correia Silva-Filho, Ana Catarina Rezende Leite, Daniel Góes Leite Gitaí, Marcelo Duzzioni, Robinson Sabino-Silva, Alexandre Urban Borbely, Olagide Wagner de Castr. Role of Modulation of Hippocampal Glucose Following Pilocarpine-Induced Status Epilepticus. Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33123979. |
role of modulation of hippocampal glucose following pilocarpine-induced status epilepticus. |
2021-10-13 |
2023-08-13 |
rat |
| Igor Santana de Melo, Yngrid Mickaelli Oliveira Dos Santos, Amanda Larissa Dias Pacheco, Maisa Araújo Costa, Vanessa de Oliveira Silva, Jucilene Freitas-Santos, Cibelle de Melo Bastos Cavalcante, Reginaldo Correia Silva-Filho, Ana Catarina Rezende Leite, Daniel Góes Leite Gitaí, Marcelo Duzzioni, Robinson Sabino-Silva, Alexandre Urban Borbely, Olagide Wagner de Castr. Role of Modulation of Hippocampal Glucose Following Pilocarpine-Induced Status Epilepticus. Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33123979. |
status epilepticus (se) is defined as continuous and self-sustaining seizures, which trigger hippocampal neurodegeneration, mitochondrial dysfunction, oxidative stress, and energy failure. |
2021-10-13 |
2023-08-13 |
rat |
| Ayako Furukawa, Akiyoshi Kakita, Yoichi Chiba, Hiroki Kitaura, Yukihiko Fujii, Masafumi Fukuda, Shigeki Kameyama, Atsuyoshi Shimad. Proteomic profile differentiating between mesial temporal lobe epilepsy with and without hippocampal sclerosis. Epilepsy research. vol 168. 2021-10-06. PMID:33197783. |
in addition, the protein carbonylation detection, an indicator of protein oxidation caused by excitotoxicity of multiple seizures and/or status epilepticus, revealed that the carbonyl level of collapsin response mediator protein 2 (crmp2) increased significantly in the sclerotic hippocampus. |
2021-10-06 |
2023-08-13 |
Not clear |
| Jing Zhu, Soojin Park, Kyoung Hoon Jeong, Won-Joo Ki. Withanolide-A treatment exerts a neuroprotective effect via inhibiting neuroinflammation in the hippocampus after pilocarpine-induced status epilepticus. Epilepsy research. vol 165. 2021-10-01. PMID:32540785. |
withanolide-a treatment exerts a neuroprotective effect via inhibiting neuroinflammation in the hippocampus after pilocarpine-induced status epilepticus. |
2021-10-01 |
2023-08-13 |
mouse |
| Kevin D Chen, Alicia M Hall, Megan M Garcia-Curran, Gissell A Sanchez, Jennifer Daglian, Renhao Luo, Tallie Z Bara. Augmented seizure susceptibility and hippocampal epileptogenesis in a translational mouse model of febrile status epilepticus. Epilepsia. vol 62. issue 3. 2021-09-21. PMID:33475157. |
augmented seizure susceptibility and hippocampal epileptogenesis in a translational mouse model of febrile status epilepticus. |
2021-09-21 |
2023-08-13 |
mouse |
| Lin Zhu, Shujuan Dai, Di Lu, Puying Xu, Lu Chen, Yanbing Han, Lianmei Zhong, Lvhua Chang, Qian W. Role of NDEL1 and VEGF/VEGFR-2 in Mouse Hippocampus After Status Epilepticus. ASN neuro. vol 12. 2021-09-15. PMID:32423231. |
role of ndel1 and vegf/vegfr-2 in mouse hippocampus after status epilepticus. |
2021-09-15 |
2023-08-13 |
mouse |
| Lin Zhu, Shujuan Dai, Di Lu, Puying Xu, Lu Chen, Yanbing Han, Lianmei Zhong, Lvhua Chang, Qian W. Role of NDEL1 and VEGF/VEGFR-2 in Mouse Hippocampus After Status Epilepticus. ASN neuro. vol 12. 2021-09-15. PMID:32423231. |
this study was performed to explore undefined alterations in the expression levels of ndel1 and vegf/vegfr-2 within the hippocampus after status epilepticus (se). |
2021-09-15 |
2023-08-13 |
mouse |
| Yan-Jun Yi, Xiao Ran, Jing Xiang, Xin-Yang Li, Li Jiang, Heng-Sheng Chen, Yue H. Effect of gap junction blockers on hippocampal ripple energy expression in rats with status epilepticus. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 23. issue 8. 2021-09-14. PMID:34511176. |
effect of gap junction blockers on hippocampal ripple energy expression in rats with status epilepticus. |
2021-09-14 |
2023-08-13 |
rat |
| Yan-Jun Yi, Xiao Ran, Jing Xiang, Xin-Yang Li, Li Jiang, Heng-Sheng Chen, Yue H. Effect of gap junction blockers on hippocampal ripple energy expression in rats with status epilepticus. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 23. issue 8. 2021-09-14. PMID:34511176. |
to study the effect of gap junction blockers, quinine (quin) and carbenoxolone (cbx), on hippocampal ripple energy expression in rats with status epilepticus (se). |
2021-09-14 |
2023-08-13 |
rat |
| Jana Tchekalarova, Tsveta Stoyanova, Rumiana Tzoneva, Violina Angelova, Pavlina Andreeva-Gatev. The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism. Neurochemical research. 2021-09-12. PMID:34510375. |
in the present study the most potent c3-modified derivative 3e, containing 2-furyl fragment was evaluated in kainate (ka)-induced status epilepticus (se) and the consequences on oxidative stress and inflammation in the hippocampus in mice were explored. |
2021-09-12 |
2023-08-13 |
mouse |
| Till S Zimmer, Bastian David, Diede W M Broekaart, Martin Schidlowski, Gabriele Ruffolo, Anatoly Korotkov, Nicole N van der Wel, Peter C van Rijen, Angelika Mühlebner, Wim van Hecke, Johannes C Baayen, Sander Idema, Liesbeth François, Jonathan van Eyll, Stefanie Dedeurwaerdere, Helmut W Kessels, Rainer Surges, Theodor Rüber, Jan A Gorter, James D Mills, Erwin A van Vliet, Eleonora Aronic. Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy. Acta neuropathologica. vol 142. issue 4. 2021-09-10. PMID:34292399. |
iron-related neuropathology and antioxidant metabolic processes were investigated in resected brain tissue from patients with temporal lobe epilepsy and hippocampal sclerosis (tle-hs), post-mortem brain tissue from patients who died after status epilepticus (se) as well as brain tissue from the electrically induced se rat model of tle. |
2021-09-10 |
2023-08-13 |
mouse |
| Grigorios Kyriatzis, Anne Bernard, Angélique Bôle, Guillaume Pflieger, Petros Chalas, Maxime Masse, Pascaline Lécorché, Guillaume Jacquot, Lotfi Ferhat, Michel Khrestchatisk. Neurotensin receptor 2 is induced in astrocytes and brain endothelial cells in relation to neuroinflammation following pilocarpine-induced seizures in rats. Glia. vol 69. issue 11. 2021-09-03. PMID:34310753. |
we show that ntsr2 protein is expressed in hippocampal astrocytes and its expression increases together with astrocyte reactivity following induction of status epilepticus. |
2021-09-03 |
2023-08-13 |
rat |
| Jeremy M Barry, J Matthew Mahoney, Gregory L Holme. Coordination of hippocampal theta and gamma oscillations relative to spatial active avoidance reflects cognitive outcome after febrile status epilepticus. Behavioral neuroscience. vol 134. issue 6. 2021-08-19. PMID:32628031. |
coordination of hippocampal theta and gamma oscillations relative to spatial active avoidance reflects cognitive outcome after febrile status epilepticus. |
2021-08-19 |
2023-08-13 |
Not clear |
| In-Young Choi, Jae Hyuk Shim, Mi-Hye Kim, Won Dong Yu, Yu Jin Kim, Gain Choi, Jae Ho Lee, Hee Jung Kim, Kyung-Ok Ch. Truncated Neogenin Promotes Hippocampal Neuronal Death after Acute Seizure. Neuroscience. vol 470. 2021-08-18. PMID:34245840. |
we show that 3 days after pilocarpine-induced status epilepticus in mice, when hippocampal cell death is detected, the level of truncated neogenin is increased, while that of full-length neogenin is decreased. |
2021-08-18 |
2023-08-13 |
mouse |
| Xing Liu, Jiefeng Geng, Haiming Guo, Huaping Zhao, Yanqiu A. Propofol inhibited apoptosis of hippocampal neurons in status epilepticus through miR-15a-5p/NR2B/ERK1/2 pathway. Cell cycle (Georgetown, Tex.). vol 19. issue 9. 2021-07-30. PMID:32212891. |
propofol inhibited apoptosis of hippocampal neurons in status epilepticus through mir-15a-5p/nr2b/erk1/2 pathway. |
2021-07-30 |
2023-08-13 |
rat |
| James Morgan, Mariana Alves, Giorgia Conte, Aida Menéndez-Méndez, Laura de Diego-Garcia, Gioacchino de Leo, Edward Beamer, Jonathon Smith, Annette Nicke, Tobias Enge. Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse. Neuroscience bulletin. vol 36. issue 11. 2021-07-28. PMID:32895896. |
while increased expression of p2x7 in the hippocampus and cortex following status epilepticus and during epilepsy has been repeatedly demonstrated, the cell type-specific expression of p2x7 and its expression in extra-hippocampal brain structures remains incompletely explored. |
2021-07-28 |
2023-08-13 |
mouse |
| James Morgan, Mariana Alves, Giorgia Conte, Aida Menéndez-Méndez, Laura de Diego-Garcia, Gioacchino de Leo, Edward Beamer, Jonathon Smith, Annette Nicke, Tobias Enge. Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse. Neuroscience bulletin. vol 36. issue 11. 2021-07-28. PMID:32895896. |
the results showed increased p2x7-egfp expression after status epilepticus induced by intra-amygdala kainic acid and during epilepsy in different brain regions including the hippocampus, cortex, striatum, thalamus and cerebellum, and this was most evident in microglia and oligodendrocytes. |
2021-07-28 |
2023-08-13 |
mouse |
| Duk-Shin Lee, Ji-Eun Ki. Regional specific activations of ERK1/2 and CDK5 differently regulate astroglial responses to ER stress in the rat hippocampus following status epilepticus. Brain research. vol 1753. 2021-07-22. PMID:33422538. |
regional specific activations of erk1/2 and cdk5 differently regulate astroglial responses to er stress in the rat hippocampus following status epilepticus. |
2021-07-22 |
2023-08-13 |
rat |
| Weiting Tang, Xinghui He, Li Feng, Dingyang Liu, Zhuanyi Yang, Junmei Zhang, Bo Xiao, Zhiquan Yan. The Role of Hippocampal Neurogenesis in ANT-DBS for LiCl-Pilocarpine-Induced Epileptic Rats. Stereotactic and functional neurosurgery. vol 99. issue 1. 2021-07-13. PMID:33302280. |
abnormal neurogenesis in the hippocampus after status epilepticus (se) has been suggested as a key pathogeny of temporal lobe epilepsy. |
2021-07-13 |
2023-08-13 |
rat |