Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zengmian Wang, Zhimin Na, Ying Cui, Chunjie Wei, Shuqiu Wan. LncRNA ZFAS1 regulates the hippocampal neurons injury in epilepsy through the miR-15a-5p/OXSR1/NF-κB pathway. Metabolic brain disease. 2022-06-25. PMID:35751788. |
therefore, the role and molecular mechanism of zfas1 in epilepsy progression deserve further investigation. mice status epilepticus (se) model was constructed, and hippocampal neurons were isolated from mice hippocampus tissues. |
2022-06-25 |
2023-08-14 |
mouse |
Samira Ramazi, Javad Fahanik-Babaei, Seyed-Mahdi Mohamadi-Zarch, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Paeonol exerts neuroprotective and anticonvulsant effects in intrahippocampal kainate model of temporal lobe epilepsy. Journal of chemical neuroanatomy. 2022-06-19. PMID:35718291. |
the results of this study showed that paeonol at the higher dose significantly reduces incidence of status epilepticus, hippocampal aberrant mossy fiber sprouting and also preserves neuronal density. |
2022-06-19 |
2023-08-14 |
Not clear |
Jinghui Zhang, Nana Qiao, Jiwen Wang, Baomin L. Nuclear translocation of GluA2/ GAPDH promotes neurotoxicity after pilocarpine-induced epilepsy. Epilepsy research. vol 183. 2022-05-31. PMID:35636277. |
in this study, induced status epilepticus (se) in rats by the systemic administration of pilocarpine, collected hippocampal tissues at different time points after se, and assessed the relationship between glua2/gapdh coupling and neuronal apoptosis in se rats. |
2022-05-31 |
2023-08-13 |
rat |
Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Tae-Cheon Kan. CDDO-Me Attenuates CA1 Neuronal Death by Facilitating RalBP1-Mediated Mitochondrial Fission and 4-HNE Efflux in the Rat Hippocampus Following Status Epilepticus. Antioxidants (Basel, Switzerland). vol 11. issue 5. 2022-05-28. PMID:35624848. |
cddo-me attenuates ca1 neuronal death by facilitating ralbp1-mediated mitochondrial fission and 4-hne efflux in the rat hippocampus following status epilepticus. |
2022-05-28 |
2023-08-13 |
rat |
Christin M Godale, Emma V Parkins, Christina Gross, Steve C Danze. Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus. Journal of molecular neuroscience : MN. 2022-05-26. PMID:35618880. |
impact of raptor and rictor deletion on hippocampal pathology following status epilepticus. |
2022-05-26 |
2023-08-13 |
mouse |
Christin M Godale, Emma V Parkins, Christina Gross, Steve C Danze. Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus. Journal of molecular neuroscience : MN. 2022-05-26. PMID:35618880. |
to circumvent the limitations of pharmacological approaches, we developed a viral/genetic strategy to delete raptor or rictor, inhibiting mtorc1 or mtorc2, respectively, from excitatory hippocampal neurons after status epilepticus in mice. |
2022-05-26 |
2023-08-13 |
mouse |
Christin M Godale, Emma V Parkins, Christina Gross, Steve C Danze. Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus. Journal of molecular neuroscience : MN. 2022-05-26. PMID:35618880. |
raptor or rictor was deleted from roughly 25% of hippocampal granule cells, with variable involvement of other hippocampal neurons, after pilocarpine status epilepticus. |
2022-05-26 |
2023-08-13 |
mouse |
Yangmei Xie, Ming Wang, Xiaolin Deng, Yinghui Che. Long non-coding RNA H19 alleviates hippocampal damage in convulsive status epilepticus rats through the nuclear factor-kappaB signaling pathway. Bioengineered. vol 13. issue 5. 2022-05-23. PMID:35603469. |
long non-coding rna h19 alleviates hippocampal damage in convulsive status epilepticus rats through the nuclear factor-kappab signaling pathway. |
2022-05-23 |
2023-08-13 |
rat |
Nagwa I Shehata, Mai A Abdelsamad, Hebat Allah A Amin, Nermin A H Sadik, Amira A Shahee. Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus. Journal of food biochemistry. 2022-05-11. PMID:35543175. |
ameliorating effect of ketogenic diet on acute status epilepticus: insights into biochemical and histological changes in rat hippocampus. |
2022-05-11 |
2023-08-13 |
rat |
Maria-Leonor López-Meraz, Dulce-Mariely Álvarez-Crod. Microglia and Status Epilepticus in the Immature Brain. Epilepsia open. 2022-05-09. PMID:35531942. |
in the developing brain, status epilepticus (se) promotes microglia activation that is associated with neuronal injury in some areas of the brain, such as the hippocampus, thalamus and amygdala. |
2022-05-09 |
2023-08-13 |
Not clear |
Adam Gorlewicz, Barbara Pijet, Krstina Orlova, Leszek Kaczmarek, Ewelina Knapsk. Epileptiform GluN2B-driven excitation in hippocampus as a therapeutic target against temporal lobe epilepsy. Experimental neurology. 2022-04-26. PMID:35469852. |
here we combined status epilepticus models of temporal lobe epilepsy, protein expression studies, and patch-clamp experiments to demonstrate the profound change in the nature of glutamatergic transmission mediated in the epileptiform hippocampus by a subpopulation of glun2b-containing nmdar receptors. |
2022-04-26 |
2023-08-13 |
Not clear |
Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Tae-Cheon Kan. Glutathione Regulates GPx1 Expression during CA1 Neuronal Death and Clasmatodendrosis in the Rat Hippocampus following Status Epilepticus. Antioxidants (Basel, Switzerland). vol 11. issue 4. 2022-04-23. PMID:35453441. |
glutathione regulates gpx1 expression during ca1 neuronal death and clasmatodendrosis in the rat hippocampus following status epilepticus. |
2022-04-23 |
2023-08-13 |
rat |
Kerry Thompso. Status epilepticus and early development: neuronal injury, neurodegeneration, and their consequences. Epilepsia open. 2022-04-18. PMID:35434910. |
this conclusion is further supported by recent clinical studies showing that prolonged febrile status epilepticus can lead to hippocampal injury, which evolves into hippocampal atrophy and hippocampal sclerosis. |
2022-04-18 |
2023-08-13 |
Not clear |
Beatriz B Aoyama, Gabriel G Zanetti, Elayne V Dias, Maria C P Athié, Iscia Lopes-Cendes, André Schwambach Vieir. Transcriptomic analysis of dorsal and ventral subiculum after induction of acute seizures by electric stimulation of the perforant pathway in rats. Hippocampus. 2022-03-28. PMID:35343006. |
however, in order to avoid generalized seizures, status epilepticus (se), and death, a state of resistance to seizures must be induced in the hippocampus by a preconditioning paradigm consisting of two daily 30-min stimulation periods. |
2022-03-28 |
2023-08-13 |
rat |
Farid Moradi, Faezeh Eslami, Nastaran Rahimi, Amirhossein Koohfar, Maryam Shayan, Mahshad Maadani, Mehdi Ghasemi, Ahmad Reza Dehpou. Modafinil exerts anticonvulsive effects against lithium-pilocarpine-induced status epilepticus in rats: A role for tumor necrosis factor-α and nitric oxide signaling. Epilepsy & behavior : E&B. vol 130. 2022-03-28. PMID:35344809. |
status epilepticus (se) is a continuous episode of seizures which leads to hippocampal neurodegeneration, severe systemic inflammation, and extreme damage to the brain. |
2022-03-28 |
2023-08-13 |
rat |
Jianwei Zhu, Yuting Yang, Wenjuan Ma, Yangyang Wang, Lihua Chen, Huan Xiong, Cheng Yin, Zongze He, Wei Fu, Ruxiang Xu, Yunfeng Li. Antiepilepticus Effects of Tetrahedral Framework Nucleic Acid via Inhibition of Gliosis-Induced Downregulation of Glutamine Synthetase and Increased AMPAR Internalization in the Postsynaptic Membrane. Nano letters. 2022-03-10. PMID:35266400. |
here, we report that tetrahedral framework nucleic acid (tfna), an assembled nucleic acid nanoparticle, showed an excellent ability to the cross blood-brain barrier (bbb) to inhibit m1 microglial activation and a1 reactive astrogliosis in the hippocampus of mice after status epilepticus. |
2022-03-10 |
2023-08-13 |
mouse |
b' Petr F\\xc3\\xa1bera, Libor Uttl, Hana Kubov\\xc3\\xa1, Grygoriy Tsenov, Pavel Mare\\xc5\\xa. Adenosine Kinase Isoforms in the Developing Rat Hippocampus after LiCl/Pilocarpine Status Epilepticus. International journal of molecular sciences. vol 23. issue 5. 2022-03-10. PMID:35269653.' |
adenosine kinase isoforms in the developing rat hippocampus after licl/pilocarpine status epilepticus. |
2022-03-10 |
2023-08-13 |
rat |
b' Petr F\\xc3\\xa1bera, Libor Uttl, Hana Kubov\\xc3\\xa1, Grygoriy Tsenov, Pavel Mare\\xc5\\xa. Adenosine Kinase Isoforms in the Developing Rat Hippocampus after LiCl/Pilocarpine Status Epilepticus. International journal of molecular sciences. vol 23. issue 5. 2022-03-10. PMID:35269653.' |
licl/pilocarpine status epilepticus (se) induced in immature rats leads, after a latent period, to hippocampal hyperexcitability. |
2022-03-10 |
2023-08-13 |
rat |
b' L K Friedman, B A Kahen, L Vel\\xc3\\xad\\xc5\\xa1ek, J Vel\\xc3\\xad\\xc5\\xa1kov\\xc3\\xa. Sex differences in behavioral pathology induced by subconvulsive stimulation during early postnatal life are overcome by epileptic activity in the pre-juvenile weanling period. Brain research. 2022-03-01. PMID:35231419.' |
the rapid repetitive entries shifted to the right in both sexes possibly be due to hippocampal injury and changes in network activity induced by status epilepticus. |
2022-03-01 |
2023-08-13 |
rat |
Dong Ah Lee, Joonwon Lee, Hyung Chan Kim, Kang Min Park, Sung Eun Ki. Hippocampal injury in patients with status epilepticus: Quantitative analysis of hippocampal volume and structural co-variance network. Seizure. vol 95. 2022-01-14. PMID:35030375. |
hippocampal injury in patients with status epilepticus: quantitative analysis of hippocampal volume and structural co-variance network. |
2022-01-14 |
2023-08-13 |
Not clear |