| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H J Ryu, J-E Kim, S-I Yeo, D-W Kim, O-S Kwon, S Y Choi, T-C Kan. F-actin depolymerization accelerates clasmatodendrosis via activation of lysosome-derived autophagic astroglial death. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21624438. |
since alteration in f-actin level influences on the formation of vacuoles/vesicles during exocytosis/endocytosis in astrocytes, we investigated whether f-actin polymerization involves clasmatodendrosis in the rat hippocampus following status epilepticus (se). |
2012-01-11 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of x-linked inhibitor of apoptosis protein. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
apoptosis and necrosis are two forms of neuronal death in post status epilepticus hippocampus, and the former has been widely studied and believed to be a major factor contributing to formation of abnormal excitatory circuit leading to refractory epileptic events. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we investigated protective effects of quercetin on status epilepticus induced hippocampal neuronal injuries in rats and focused on two major proteins, the x-linked inhibitor of apoptosis protein, a key member of the inhibitor of apoptosis protein family, and the caspase-3 protein, a common effector for the execution-phase of cell signaling apoptotic pathways. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we found expression alterations of x-linked inhibitor of apoptosis protein and caspase-3 protein in post status epilepticus hippocampus, along with an alteration in the number of apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
furthermore, quercetin treatment in rats undergoing status epilepticus led to an interventional effect on expression of x-linked inhibitor of apoptosis protein and the caspase-3 protein, with a corresponding positive change on the number of hippocampal apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
together, the study suggests neuroprotective effects of quercetin on hippocampal injury post status epilepticus and the effects may be associated with regulation of the x-linked inhibitor of apoptosis protein and the caspase-3 protein, which can be a decisive factor for apoptosis and survival of neurons in hippocampus. |
2012-01-04 |
2023-08-12 |
rat |
| Melodie R Winawer, Sandra S Gildersleeve, Austin G Phillips, Daniel Rabinowitz, Abraham A Palme. Mapping a mouse limbic seizure susceptibility locus on chromosome 10. Epilepsia. vol 52. issue 11. 2011-12-19. PMID:21906048. |
using c57bl/6j × a/j chromosome substitution strains (css), we previously identified a locus on mouse chromosome 10 (ch10) conferring susceptibility to pilocarpine, a muscarinic cholinergic agonist that models human temporal lobe epilepsy by inducing initial limbic seizures and status epilepticus (status), followed by hippocampal cell loss and delayed-onset chronic spontaneous limbic seizures. |
2011-12-19 |
2023-08-12 |
mouse |
| G E Serrano, N Lelutiu, A Rojas, S Cochi, R Shaw, C D Makinson, D Wang, G A FitzGerald, R Dingledin. Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 42. 2011-12-08. PMID:22016518. |
results following pilocarpine-induced status epilepticus indicate that neuronal cox-2 promotes early neuroprotection and then delayed neurodegeneration of ca1 pyramidal neurons, promotes neurodegeneration of nearby somatostatin interneurons in the ca1 stratum oriens and dentate hilus (which themselves do not express cox-2), intensifies a broad inflammatory reaction involving numerous cytokines and other inflammatory mediators in the hippocampus, and is essential for development of a leaky blood-brain barrier after seizures. |
2011-12-08 |
2023-08-12 |
mouse |
| Ashok K Shett. Promise of resveratrol for easing status epilepticus and epilepsy. Pharmacology & therapeutics. vol 131. issue 3. 2011-12-07. PMID:21554899. |
next, the detrimental effects of acute seizures or status epilepticus on the hippocampus and the implications of post-status epilepticus changes in the hippocampus towards the occurrence of chronic epilepsy and cognitive dysfunction are summarized. |
2011-12-07 |
2023-08-12 |
Not clear |
| Anna Guzik-Kornacka, Anna Sliwa, Gabriela Plucinska, Katarzyna Lukasiu. Status epilepticus evokes prolonged increase in the expression of CCL3 and CCL4 mRNA and protein in the rat brain. Acta neurobiologiae experimentalis. vol 71. issue 2. 2011-11-03. PMID:21731074. |
expression of ccl3 and ccl4 proteins was elevated in astrocytes in the enthorinal and piriform cortices, amygdala, and hippocampus showing the largest increase at 4d after status epilepticus. |
2011-11-03 |
2023-08-12 |
human |
| Jian Xin Liu, Yong Liu, Feng Ru Tan. Pilocarpine-induced status epilepticus alters hippocampal PKC expression in mice. Acta neurobiologiae experimentalis. vol 71. issue 2. 2011-11-03. PMID:21731076. |
pilocarpine-induced status epilepticus alters hippocampal pkc expression in mice. |
2011-11-03 |
2023-08-12 |
mouse |
| Jian Xin Liu, Yong Liu, Feng Ru Tan. Pilocarpine-induced status epilepticus alters hippocampal PKC expression in mice. Acta neurobiologiae experimentalis. vol 71. issue 2. 2011-11-03. PMID:21731076. |
we investigated the protein expression of different protein kinase c (pkc) isoforms (pkc-alpha, pkc-beta1, pkc-beta2, pkc-gamma, pkc-delta, pkc-epsilon, pkc-eta and pkc-zeta) in the hippocampus of normal control mice and progressive changes in pkc isoforms expression during and after pilocarpine induced status epilepticus (pise). |
2011-11-03 |
2023-08-12 |
mouse |
| Z Kohl, G Uyanik, R Lürding, G Schuierer, U Bogdahn, M Schröder, N Weidne. Selective bilateral hippocampal lesions after theophylline-induced status epilepticus causes a permanent amnesic syndrome. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 7. 2011-10-24. PMID:21550250. |
selective bilateral hippocampal lesions after theophylline-induced status epilepticus causes a permanent amnesic syndrome. |
2011-10-24 |
2023-08-12 |
Not clear |
| H J Ryu, J-E Kim, S-I Yeo, M-J Kim, S-M Jo, T-C Kan. ReLA/P65-serine 536 nuclear factor-kappa B phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus. Neuroscience. vol 187. 2011-10-05. PMID:21550382. |
rela/p65-serine 536 nuclear factor-kappa b phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus. |
2011-10-05 |
2023-08-12 |
rat |
| Ji-Eun Kim, Hea Jin Ryu, Tae-Cheon Kan. P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus. Journal of neuroinflammation. vol 8. 2011-10-03. PMID:21631954. |
p2x7 receptor activation ameliorates ca3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus. |
2011-10-03 |
2023-08-12 |
rat |
| Wei-ping Wang, Zhi-qin Shi, Jiang-hua Yu, Li Guo, Le Wang, Dong-liang Han, Dong-cai Yuan, Ying-zhuo Zan. [Effect of recombinant human erythropoietin on hippocampal p-Akt and caspase-9 expressions in rats with status epilepticus and the mechanism]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 30. issue 1. 2011-08-12. PMID:20117987. |
[effect of recombinant human erythropoietin on hippocampal p-akt and caspase-9 expressions in rats with status epilepticus and the mechanism]. |
2011-08-12 |
2023-08-12 |
human |
| Wei-ping Wang, Zhi-qin Shi, Jiang-hua Yu, Li Guo, Le Wang, Dong-liang Han, Dong-cai Yuan, Ying-zhuo Zan. [Effect of recombinant human erythropoietin on hippocampal p-Akt and caspase-9 expressions in rats with status epilepticus and the mechanism]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 30. issue 1. 2011-08-12. PMID:20117987. |
to observe the effect of recombinant human erythropoietin (rhuepo) on p-akt and caspase-9 expressions in the hippocampus of rats with status epilepticus (se) and explore the neuroprotective mechanism of rhuepo. |
2011-08-12 |
2023-08-12 |
human |
| Yi-Jun Song, Xiao-Bing Tian, Shu Zhang, Ya-Xi Zhang, Xin Li, Dai Li, Yan Cheng, Jiang-Nin Zhang, Chu-Sheng Kang, Wen Zha. Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b. Brain research. vol 1387. 2011-08-03. PMID:21376023. |
furthermore, let-7 e and mir-23 a/b analysis in rat hippocampus were performed by real-time quantitative polymerase chain reaction at 0 h, 1h, 6h, 12h, 24h, 2 days, 7 days,10 days, 30 days,50 days after induction of status epilepticus (se). |
2011-08-03 |
2023-08-12 |
rat |
| Rafaela R F Pestana, Erika R Kinjo, Marina S Hernandes, Luiz R G Britt. Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy. Neuroscience letters. vol 484. issue 3. 2011-08-02. PMID:20732386. |
we first determined the spatio-temporal pattern of ros generation, by means of detection with dihydroethidium oxidation, in the ca1 and ca3 areas and the dentate gyrus of the dorsal hippocampus during status epilepticus induced by pilocarpine. |
2011-08-02 |
2023-08-12 |
rat |