| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Rami, M Kim, J Niquet, A Langhage. Alterations in the expression of the anti-apoptotic factor HAX-1 upon seizures-induced hippocampal injury in the neonatal rat brain. Neurochemical research. vol 37. issue 1. 2012-05-09. PMID:21909957. |
status epilepticus in the immature brain significantly induced increased cytosolic accumulation of hax-1 in a biphasic manner, induced an upregulation of htra2 and enhanced caspase-3 activity in the selectively vulnerable hippocampal ca1-subfield. |
2012-05-09 |
2023-08-12 |
rat |
| Steve Gibbs, Bidisha Chattopadhyaya, Sébastien Desgent, Patricia N Awad, Olivier Clerk-Lamalice, Maxime Levesque, Rose-Mari Vianna, Rose-Marie Rébillard, Andrée-Anne Delsemme, David Hébert, Luc Tremblay, Martin Lepage, Laurent Descarries, Graziella Di Cristo, Lionel Carman. Long-term consequences of a prolonged febrile seizure in a dual pathology model. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21406232. |
clinical evidence suggests that febrile status epilepticus (se) in children can lead to acute hippocampal injury and subsequent temporal lobe epilepsy. |
2012-05-07 |
2023-08-12 |
rat |
| Angelisa Frasca, Marlien Aalbers, Federica Frigerio, Fabio Fiordaliso, Monica Salio, Marco Gobbi, Alfredo Cagnotto, Fabrizio Gardoni, Giorgio S Battaglia, Govert Hoogland, Monica Di Luca, Annamaria Vezzan. Misplaced NMDA receptors in epileptogenesis contribute to excitotoxicity. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21575722. |
pharmacological blockade of nr2b-containing n-methyl-d-aspartate receptors (nmdars) during epileptogenesis reduces neurodegeneration provoked in the rodent hippocampus by status epilepticus. |
2012-05-07 |
2023-08-12 |
rat |
| Angelisa Frasca, Marlien Aalbers, Federica Frigerio, Fabio Fiordaliso, Monica Salio, Marco Gobbi, Alfredo Cagnotto, Fabrizio Gardoni, Giorgio S Battaglia, Govert Hoogland, Monica Di Luca, Annamaria Vezzan. Misplaced NMDA receptors in epileptogenesis contribute to excitotoxicity. Neurobiology of disease. vol 43. issue 2. 2012-05-07. PMID:21575722. |
levels of tyr1472 phosphorylated nr2b subunit decreased in the post-synaptic membranes from rat hippocampus during epileptogenesis induced by electrical status epilepticus. |
2012-05-07 |
2023-08-12 |
rat |
| Jianxiong Jiang, Thota Ganesh, Yuhong Du, Yi Quan, Geidy Serrano, Min Qui, Iris Speigel, Asheebo Rojas, Nadia Lelutiu, Raymond Dingledin. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 8. 2012-04-12. PMID:22323596. |
a brain-permeant compound completely suppressed the up-regulation of cox-2 mrna in rat cultured microglia by ep2 activation and significantly reduced neuronal injury in hippocampus when administered in mice beginning 1 h after termination of pilocarpine-induced status epilepticus. |
2012-04-12 |
2023-08-12 |
mouse |
| Chirag Upreti, Rafael Otero, Carlos Partida, Frank Skinner, Ravi Thakker, Luis F Pacheco, Zhen-yu Zhou, Giorgi Maglakelidze, Jana Velíšková, Libor Velíšek, Dwight Romanovicz, Theresa Jones, Patric K Stanton, Emilio R Garrido-Sanabri. Altered neurotransmitter release, vesicle recycling and presynaptic structure in the pilocarpine model of temporal lobe epilepsy. Brain : a journal of neurology. vol 135. issue Pt 3. 2012-04-09. PMID:22344585. |
to measure directly the long-term effects of pilocarpine-induced status epilepticus on vesicular release and recycling in hippocampal mossy fibre presynaptic boutons, we used (i) two-photon imaging of fm1-43 vesicular release in rat hippocampal slices; and (ii) transgenic mice expressing the genetically encoded ph-sensitive fluorescent reporter synaptophluorin preferentially at glutamatergic synapses. |
2012-04-09 |
2023-08-12 |
mouse |
| Wei-Ping Wang, Yan Lou, Zhen-Zhong Li, Pan Li, Rui-Sheng Dua. [Change of hippocampal NMDA receptor and emotional behavior and spatial learning and memory in status epilepticus rat model]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 23. issue 1. 2012-03-26. PMID:21171367. |
[change of hippocampal nmda receptor and emotional behavior and spatial learning and memory in status epilepticus rat model]. |
2012-03-26 |
2023-08-12 |
rat |
| Suzanne F C Miller-Delaney, Sudipto Das, Takanori Sano, Eva M Jimenez-Mateos, Kenneth Bryan, Patrick G Buckley, Raymond L Stallings, David C Henshal. Differential DNA methylation patterns define status epilepticus and epileptic tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 5. 2012-03-22. PMID:22302800. |
prolonged seizures (status epilepticus) produce pathophysiological changes in the hippocampus that are associated with large-scale, wide-ranging changes in gene expression. |
2012-03-22 |
2023-08-12 |
mouse |
| Suzanne F C Miller-Delaney, Sudipto Das, Takanori Sano, Eva M Jimenez-Mateos, Kenneth Bryan, Patrick G Buckley, Raymond L Stallings, David C Henshal. Differential DNA methylation patterns define status epilepticus and epileptic tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 5. 2012-03-22. PMID:22302800. |
here, through methylation analysis of 34,143 discrete loci representing all annotated cpg islands and promoter regions in the mouse genome, we report the genome-wide dna methylation changes in the hippocampus after status epilepticus and epileptic tolerance in adult mice. |
2012-03-22 |
2023-08-12 |
mouse |
| Suzanne F C Miller-Delaney, Sudipto Das, Takanori Sano, Eva M Jimenez-Mateos, Kenneth Bryan, Patrick G Buckley, Raymond L Stallings, David C Henshal. Differential DNA methylation patterns define status epilepticus and epileptic tolerance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 5. 2012-03-22. PMID:22302800. |
the present study reports select, genome-wide dna methylation changes after status epilepticus and in epileptic tolerance, which may contribute to regulating the gene expression environment of the seizure-damaged hippocampus. |
2012-03-22 |
2023-08-12 |
mouse |
| H Steve White, Anitha B Alex, Amanda Pollock, Naama Hen, Tawfeeq Shekh-Ahmad, Karen S Wilcox, John H McDonough, James P Stables, Dan Kaufmann, Boris Yagen, Meir Biale. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia. vol 53. issue 1. 2012-02-24. PMID:22150444. |
the study reported herein evaluated the anticonvulsant activity of spd in a battery of rodent seizure and epilepsy models and assessed its efficacy in rat and guinea pig models of status epilepticus (se) and neuroprotection in an organotypic hippocampal slice model of excitotoxic cell death. |
2012-02-24 |
2023-08-12 |
rat |
| Xiaomei Shu, Shuzhen Du, Xuemei Chen, Zhenhong L. Transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. Cell biochemistry and biophysics. vol 61. issue 2. 2012-02-23. PMID:21706365. |
transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. |
2012-02-23 |
2023-08-12 |
rat |
| Xiaomei Shu, Shuzhen Du, Xuemei Chen, Zhenhong L. Transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. Cell biochemistry and biophysics. vol 61. issue 2. 2012-02-23. PMID:21706365. |
in this study, we studied the effects of hippocampal transplantation of neural stem cells (nscs) overexpressing cardiotrophin 1 (ct1) on hippocampal mossy fiber sprouting (mfs) in a rat model of status epilepticus (se). |
2012-02-23 |
2023-08-12 |
rat |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
mir21 and its co-transcript mir21, micrornas produced from either the 5' or 3' ends of the same precursor rna strand, are increased in the hippocampus following status epilepticus. |
2012-02-21 |
2023-08-12 |
Not clear |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
treatment of hippocampal neuronal cultures with excess k(+)cl(-), a depolarizing agent mimicking the episode of status epilepticus, also results in an increase in mir21 and a decrease in neurotrophin-3 mrna. |
2012-02-21 |
2023-08-12 |
Not clear |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
mir21 is a candidate for regulating neurotrophin-3 signaling in the hippocampus following status epilepticus. |
2012-02-21 |
2023-08-12 |
Not clear |
| b' Norbert K\\xc3\\xa1roly, Andr\\xc3\\xa1s Mih\\xc3\\xa1ly, Endre Dob\\xc3\\xb. Comparative immunohistochemistry of synaptic markers in the rodent hippocampus in pilocarpine epilepsy. Acta histochemica. vol 113. issue 6. 2012-02-16. PMID:20846710.' |
pilocarpine-induced epileptic state (status epilepticus) generates an aberrant sprouting of hippocampal mossy fibers, which alter the intrahippocampal circuits. |
2012-02-16 |
2023-08-12 |
mouse |
| William A Gomes, Shlomo Shinna. Prospects for imaging-related biomarkers of human epileptogenesis: a critical review. Biomarkers in medicine. vol 5. issue 5. 2012-02-14. PMID:22003908. |
hippocampal volumetry and t(2) relaxometry are proposed as candidate biomarkers of epileptogenesis in temporal lobe epilepsy following febrile status epilepticus. |
2012-02-14 |
2023-08-12 |
human |
| Sarah J E Wong-Goodrich, Melissa J Glenn, Tiffany J Mellott, Yi B Liu, Jan K Blusztajn, Christina L William. Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus. vol 21. issue 6. 2012-02-10. PMID:20232399. |
status epilepticus (se) in adulthood dramatically alters the hippocampus and produces spatial learning and memory deficits. |
2012-02-10 |
2023-08-12 |
rat |
| Melanie Langer, Claudia Brandt, Wolfgang Lösche. Marked strain and substrain differences in induction of status epilepticus and subsequent development of neurodegeneration, epilepsy, and behavioral alterations in rats. [corrected]. Epilepsy research. vol 96. issue 3. 2012-02-07. PMID:21723093. |
outbred rat strains such as sprague-dawley (sd) or wistar are widely used in epilepsy models, including popular models of temporal lobe epilepsy in which spontaneous recurrent seizures (srs), hippocampal damage, and behavioral alterations develop after status epilepticus (se). |
2012-02-07 |
2023-08-12 |
rat |