| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Steve White, Anitha B Alex, Amanda Pollock, Naama Hen, Tawfeeq Shekh-Ahmad, Karen S Wilcox, John H McDonough, James P Stables, Dan Kaufmann, Boris Yagen, Meir Biale. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia. vol 53. issue 1. 2012-02-24. PMID:22150444. |
the study reported herein evaluated the anticonvulsant activity of spd in a battery of rodent seizure and epilepsy models and assessed its efficacy in rat and guinea pig models of status epilepticus (se) and neuroprotection in an organotypic hippocampal slice model of excitotoxic cell death. |
2012-02-24 |
2023-08-12 |
rat |
| Xiaomei Shu, Shuzhen Du, Xuemei Chen, Zhenhong L. Transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. Cell biochemistry and biophysics. vol 61. issue 2. 2012-02-23. PMID:21706365. |
transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. |
2012-02-23 |
2023-08-12 |
rat |
| Xiaomei Shu, Shuzhen Du, Xuemei Chen, Zhenhong L. Transplantation of neural stem cells overexpressing cardiotrophin-1 inhibits sprouting of hippocampal mossy fiber in a rat model of status epilepticus. Cell biochemistry and biophysics. vol 61. issue 2. 2012-02-23. PMID:21706365. |
in this study, we studied the effects of hippocampal transplantation of neural stem cells (nscs) overexpressing cardiotrophin 1 (ct1) on hippocampal mossy fiber sprouting (mfs) in a rat model of status epilepticus (se). |
2012-02-23 |
2023-08-12 |
rat |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
mir21 and its co-transcript mir21, micrornas produced from either the 5' or 3' ends of the same precursor rna strand, are increased in the hippocampus following status epilepticus. |
2012-02-21 |
2023-08-12 |
Not clear |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
treatment of hippocampal neuronal cultures with excess k(+)cl(-), a depolarizing agent mimicking the episode of status epilepticus, also results in an increase in mir21 and a decrease in neurotrophin-3 mrna. |
2012-02-21 |
2023-08-12 |
Not clear |
| Rashmi M Risbud, Carolyn Lee, Brenda E Porte. Neurotrophin-3 mRNA a putative target of miR21 following status epilepticus. Brain research. vol 1424. 2012-02-21. PMID:22019057. |
mir21 is a candidate for regulating neurotrophin-3 signaling in the hippocampus following status epilepticus. |
2012-02-21 |
2023-08-12 |
Not clear |
| b' Norbert K\\xc3\\xa1roly, Andr\\xc3\\xa1s Mih\\xc3\\xa1ly, Endre Dob\\xc3\\xb. Comparative immunohistochemistry of synaptic markers in the rodent hippocampus in pilocarpine epilepsy. Acta histochemica. vol 113. issue 6. 2012-02-16. PMID:20846710.' |
pilocarpine-induced epileptic state (status epilepticus) generates an aberrant sprouting of hippocampal mossy fibers, which alter the intrahippocampal circuits. |
2012-02-16 |
2023-08-12 |
mouse |
| William A Gomes, Shlomo Shinna. Prospects for imaging-related biomarkers of human epileptogenesis: a critical review. Biomarkers in medicine. vol 5. issue 5. 2012-02-14. PMID:22003908. |
hippocampal volumetry and t(2) relaxometry are proposed as candidate biomarkers of epileptogenesis in temporal lobe epilepsy following febrile status epilepticus. |
2012-02-14 |
2023-08-12 |
human |
| Sarah J E Wong-Goodrich, Melissa J Glenn, Tiffany J Mellott, Yi B Liu, Jan K Blusztajn, Christina L William. Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus. vol 21. issue 6. 2012-02-10. PMID:20232399. |
status epilepticus (se) in adulthood dramatically alters the hippocampus and produces spatial learning and memory deficits. |
2012-02-10 |
2023-08-12 |
rat |
| Melanie Langer, Claudia Brandt, Wolfgang Lösche. Marked strain and substrain differences in induction of status epilepticus and subsequent development of neurodegeneration, epilepsy, and behavioral alterations in rats. [corrected]. Epilepsy research. vol 96. issue 3. 2012-02-07. PMID:21723093. |
outbred rat strains such as sprague-dawley (sd) or wistar are widely used in epilepsy models, including popular models of temporal lobe epilepsy in which spontaneous recurrent seizures (srs), hippocampal damage, and behavioral alterations develop after status epilepticus (se). |
2012-02-07 |
2023-08-12 |
rat |
| K H Jeong, K-E Lee, S Y Kim, K-O Ch. Upregulation of Krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. Neuroscience. vol 186. 2012-01-30. PMID:21362463. |
upregulation of krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. |
2012-01-30 |
2023-08-12 |
mouse |
| K H Jeong, K-E Lee, S Y Kim, K-O Ch. Upregulation of Krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. Neuroscience. vol 186. 2012-01-30. PMID:21362463. |
therefore, the present study investigated the temporal pattern of klf6 expression in the mouse hippocampus and identified cell types expressing klf6 after pilocarpine-induced status epilepticus (se). |
2012-01-30 |
2023-08-12 |
mouse |
| Y X Han, Y T Lin, J J Xu, L L Cao, X W Liu, H Jiang, Z F Ch. Status epilepticus stimulates peroxisome proliferator-activated receptor γ coactivator 1-α/mitochondrial antioxidant system pathway by a nitric oxide-dependent mechanism. Neuroscience. vol 186. 2012-01-30. PMID:21536107. |
here we showed that pilocarpine-induced status epilepticus (se) stimulates the pgc-1α/mitochondrial antioxidant system signaling pathway in the rat hippocampus. |
2012-01-30 |
2023-08-12 |
rat |
| Eva M Jimenez-Mateos, Isabella Bray, Amaya Sanz-Rodriguez, Tobias Engel, Ross C McKiernan, Genshin Mouri, Katsuhiro Tanaka, Takanori Sano, Julie A Saugstad, Roger P Simon, Raymond L Stallings, David C Henshal. miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. The American journal of pathology. vol 179. issue 5. 2012-01-24. PMID:21945804. |
mirna expression profile after status epilepticus and hippocampal neuroprotection by targeting mir-132. |
2012-01-24 |
2023-08-12 |
mouse |
| Juha T Järvelä, Saku Ruohonen, Tiina-Kaisa Kukko-Lukjanov, Anna Plysjuk, Francisco R Lopez-Picon, Irma E Holopaine. Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:20932983. |
in the postnatal rodent hippocampus status epilepticus (se) leads to age- and region-specific excitotoxic neuronal damage, the precise mechanisms of which are still incompletely known. |
2012-01-18 |
2023-08-12 |
Not clear |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. |
2012-01-18 |
2023-08-12 |
rat |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
status epilepticus was induced in postnatal day 20 sprague-dawley rat pups with the chemoconvulsant lithium-pilocarpine and brain tissue was examined with fluoro-jade b. horizontal sections (n=7) favoring a visualization of the ventral hippocampus showed marked fluoro-jade b staining in ca1, ca3, and hilar region. |
2012-01-18 |
2023-08-12 |
rat |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
these results demonstrate that in ventral hippocampus, lithium pilocarpine-induced status epilepticus consistently results in hippocampal neuronal injury in postnatal day 20 rats. |
2012-01-18 |
2023-08-12 |
rat |
| C F Bortolatto, C R Jesse, E A Wilhelm, L R Ribeiro, L M Rambo, L F F Royes, S S Roman, C W Nogueir. Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus. Neuroscience. vol 193. 2012-01-18. PMID:21820494. |
in conclusion, the present study showed that dtds attenuated ka-induced status epilepticus in rats and the subsequent hippocampal damage. |
2012-01-18 |
2023-08-12 |
rat |
| Chia-Chu Chiang, Ming-Shaung Ju, Chou-Ching K Li. Description and computational modeling of the whole course of status epilepticus induced by low dose lithium-pilocarpine in rats. Brain research. vol 1417. 2012-01-18. PMID:21911214. |
the main purposes of this study were (1) to describe the whole course of status epilepticus induced by a low dose lithium-pilocarpine model in rats, including depth-eeg from the hippocampus, ecog from cortex and gross behaviors, and (2) to investigate the possible changes of the intrinsic neural network in the hippocampus during the status epilepticus by model simulation. |
2012-01-18 |
2023-08-12 |
rat |