| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K H Jeong, K-E Lee, S Y Kim, K-O Ch. Upregulation of Krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. Neuroscience. vol 186. 2012-01-30. PMID:21362463. |
upregulation of krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. |
2012-01-30 |
2023-08-12 |
mouse |
| K H Jeong, K-E Lee, S Y Kim, K-O Ch. Upregulation of Krüppel-like factor 6 in the mouse hippocampus after pilocarpine-induced status epilepticus. Neuroscience. vol 186. 2012-01-30. PMID:21362463. |
therefore, the present study investigated the temporal pattern of klf6 expression in the mouse hippocampus and identified cell types expressing klf6 after pilocarpine-induced status epilepticus (se). |
2012-01-30 |
2023-08-12 |
mouse |
| Y X Han, Y T Lin, J J Xu, L L Cao, X W Liu, H Jiang, Z F Ch. Status epilepticus stimulates peroxisome proliferator-activated receptor γ coactivator 1-α/mitochondrial antioxidant system pathway by a nitric oxide-dependent mechanism. Neuroscience. vol 186. 2012-01-30. PMID:21536107. |
here we showed that pilocarpine-induced status epilepticus (se) stimulates the pgc-1α/mitochondrial antioxidant system signaling pathway in the rat hippocampus. |
2012-01-30 |
2023-08-12 |
rat |
| Eva M Jimenez-Mateos, Isabella Bray, Amaya Sanz-Rodriguez, Tobias Engel, Ross C McKiernan, Genshin Mouri, Katsuhiro Tanaka, Takanori Sano, Julie A Saugstad, Roger P Simon, Raymond L Stallings, David C Henshal. miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. The American journal of pathology. vol 179. issue 5. 2012-01-24. PMID:21945804. |
mirna expression profile after status epilepticus and hippocampal neuroprotection by targeting mir-132. |
2012-01-24 |
2023-08-12 |
mouse |
| Juha T Järvelä, Saku Ruohonen, Tiina-Kaisa Kukko-Lukjanov, Anna Plysjuk, Francisco R Lopez-Picon, Irma E Holopaine. Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:20932983. |
in the postnatal rodent hippocampus status epilepticus (se) leads to age- and region-specific excitotoxic neuronal damage, the precise mechanisms of which are still incompletely known. |
2012-01-18 |
2023-08-12 |
Not clear |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. |
2012-01-18 |
2023-08-12 |
rat |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
status epilepticus was induced in postnatal day 20 sprague-dawley rat pups with the chemoconvulsant lithium-pilocarpine and brain tissue was examined with fluoro-jade b. horizontal sections (n=7) favoring a visualization of the ventral hippocampus showed marked fluoro-jade b staining in ca1, ca3, and hilar region. |
2012-01-18 |
2023-08-12 |
rat |
| J J Ekstrand, W Pouliot, P Scheerlinck, F E Dude. Lithium pilocarpine-induced status epilepticus in postnatal day 20 rats results in greater neuronal injury in ventral versus dorsal hippocampus. Neuroscience. vol 192. 2012-01-18. PMID:21669257. |
these results demonstrate that in ventral hippocampus, lithium pilocarpine-induced status epilepticus consistently results in hippocampal neuronal injury in postnatal day 20 rats. |
2012-01-18 |
2023-08-12 |
rat |
| C F Bortolatto, C R Jesse, E A Wilhelm, L R Ribeiro, L M Rambo, L F F Royes, S S Roman, C W Nogueir. Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus. Neuroscience. vol 193. 2012-01-18. PMID:21820494. |
in conclusion, the present study showed that dtds attenuated ka-induced status epilepticus in rats and the subsequent hippocampal damage. |
2012-01-18 |
2023-08-12 |
rat |
| Chia-Chu Chiang, Ming-Shaung Ju, Chou-Ching K Li. Description and computational modeling of the whole course of status epilepticus induced by low dose lithium-pilocarpine in rats. Brain research. vol 1417. 2012-01-18. PMID:21911214. |
the main purposes of this study were (1) to describe the whole course of status epilepticus induced by a low dose lithium-pilocarpine model in rats, including depth-eeg from the hippocampus, ecog from cortex and gross behaviors, and (2) to investigate the possible changes of the intrinsic neural network in the hippocampus during the status epilepticus by model simulation. |
2012-01-18 |
2023-08-12 |
rat |
| H J Ryu, J-E Kim, S-I Yeo, D-W Kim, O-S Kwon, S Y Choi, T-C Kan. F-actin depolymerization accelerates clasmatodendrosis via activation of lysosome-derived autophagic astroglial death. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21624438. |
since alteration in f-actin level influences on the formation of vacuoles/vesicles during exocytosis/endocytosis in astrocytes, we investigated whether f-actin polymerization involves clasmatodendrosis in the rat hippocampus following status epilepticus (se). |
2012-01-11 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of x-linked inhibitor of apoptosis protein. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
apoptosis and necrosis are two forms of neuronal death in post status epilepticus hippocampus, and the former has been widely studied and believed to be a major factor contributing to formation of abnormal excitatory circuit leading to refractory epileptic events. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we investigated protective effects of quercetin on status epilepticus induced hippocampal neuronal injuries in rats and focused on two major proteins, the x-linked inhibitor of apoptosis protein, a key member of the inhibitor of apoptosis protein family, and the caspase-3 protein, a common effector for the execution-phase of cell signaling apoptotic pathways. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
we found expression alterations of x-linked inhibitor of apoptosis protein and caspase-3 protein in post status epilepticus hippocampus, along with an alteration in the number of apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
furthermore, quercetin treatment in rats undergoing status epilepticus led to an interventional effect on expression of x-linked inhibitor of apoptosis protein and the caspase-3 protein, with a corresponding positive change on the number of hippocampal apoptotic and surviving neurons. |
2012-01-04 |
2023-08-12 |
rat |
| Kai Hu, Shu-Yu Li, Bo Xiao, Fang-fang Bi, Xiao-Qin Lu, Xiao-Mei W. Protective effects of quercetin against status epilepticus induced hippocampal neuronal injury in rats: involvement of X-linked inhibitor of apoptosis protein. Acta neurologica Belgica. vol 111. issue 3. 2012-01-04. PMID:22141284. |
together, the study suggests neuroprotective effects of quercetin on hippocampal injury post status epilepticus and the effects may be associated with regulation of the x-linked inhibitor of apoptosis protein and the caspase-3 protein, which can be a decisive factor for apoptosis and survival of neurons in hippocampus. |
2012-01-04 |
2023-08-12 |
rat |
| Melodie R Winawer, Sandra S Gildersleeve, Austin G Phillips, Daniel Rabinowitz, Abraham A Palme. Mapping a mouse limbic seizure susceptibility locus on chromosome 10. Epilepsia. vol 52. issue 11. 2011-12-19. PMID:21906048. |
using c57bl/6j × a/j chromosome substitution strains (css), we previously identified a locus on mouse chromosome 10 (ch10) conferring susceptibility to pilocarpine, a muscarinic cholinergic agonist that models human temporal lobe epilepsy by inducing initial limbic seizures and status epilepticus (status), followed by hippocampal cell loss and delayed-onset chronic spontaneous limbic seizures. |
2011-12-19 |
2023-08-12 |
mouse |
| G E Serrano, N Lelutiu, A Rojas, S Cochi, R Shaw, C D Makinson, D Wang, G A FitzGerald, R Dingledin. Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 42. 2011-12-08. PMID:22016518. |
results following pilocarpine-induced status epilepticus indicate that neuronal cox-2 promotes early neuroprotection and then delayed neurodegeneration of ca1 pyramidal neurons, promotes neurodegeneration of nearby somatostatin interneurons in the ca1 stratum oriens and dentate hilus (which themselves do not express cox-2), intensifies a broad inflammatory reaction involving numerous cytokines and other inflammatory mediators in the hippocampus, and is essential for development of a leaky blood-brain barrier after seizures. |
2011-12-08 |
2023-08-12 |
mouse |
| Ashok K Shett. Promise of resveratrol for easing status epilepticus and epilepsy. Pharmacology & therapeutics. vol 131. issue 3. 2011-12-07. PMID:21554899. |
next, the detrimental effects of acute seizures or status epilepticus on the hippocampus and the implications of post-status epilepticus changes in the hippocampus towards the occurrence of chronic epilepsy and cognitive dysfunction are summarized. |
2011-12-07 |
2023-08-12 |
Not clear |