| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul S Buckmaster, Emily Abrams, Xiling We. Seizure frequency correlates with loss of dentate gyrus GABAergic neurons in a mouse model of temporal lobe epilepsy. The Journal of comparative neurology. vol 525. issue 11. 2018-03-19. PMID:28425097. |
fvb mice (n = 127) that had experienced status epilepticus after systemic treatment with pilocarpine 31-61 days earlier were video-monitored for spontaneous, convulsive seizures 9 hr/day every day for 24-36 days. |
2018-03-19 |
2023-08-13 |
mouse |
| Kun Zhu, Bo Yuan, Ming Hu, Gai-Feng Feng, Yong Liu, Jian-Xin Li. Reduced abnormal integration of adult-generated granule cells does not attenuate spontaneous recurrent seizures in mice. Epilepsy research. vol 133. 2018-03-12. PMID:28431266. |
in this study, we ablated the hippocampal neurogenesis by methylazoxymethanol acetate (mam) treatment both before and after pilocarpine induced status epilepticus (se). |
2018-03-12 |
2023-08-13 |
mouse |
| Raymond Dingledine, Douglas A Coulter, Brita Fritsch, Jan A Gorter, Nadia Lelutiu, James McNamara, J Victor Nadler, Asla Pitkänen, Michael A Rogawski, Pate Skene, Robert S Sloviter, Yu Wang, Wytse J Wadman, Claude Wasterlain, Avtar Roopr. Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Scientific data. vol 4. 2018-03-02. PMID:28485718. |
we attempted to minimize these confounds by pooling dentate granule cell transcriptional profiles from 164 rats in seven laboratories, using three status epilepticus (se) epilepsy models (pilocarpine, kainate, self-sustained se), plus amygdala kindling. |
2018-03-02 |
2023-08-13 |
rat |
| Jian-Xin Liu, Xia Cao, Yong Liu, Feng-Ru Tan. Altered expression of neuronal CCR6 during pilocarpine induced status epilepticus in mice. Epilepsy research. vol 126. 2017-12-19. PMID:27423018. |
altered expression of neuronal ccr6 during pilocarpine induced status epilepticus in mice. |
2017-12-19 |
2023-08-13 |
mouse |
| Jian-Xin Liu, Xia Cao, Yong Liu, Feng-Ru Tan. Altered expression of neuronal CCR6 during pilocarpine induced status epilepticus in mice. Epilepsy research. vol 126. 2017-12-19. PMID:27423018. |
during pilocarpine induced status epilepticus, a transient down-regulation of neuronal ccr6 in the stratum oriens of ca1 was demonstrated at 2h during status epilepticus. |
2017-12-19 |
2023-08-13 |
mouse |
| Shintaro Otsuka, Taro Ohkido, Makoto Itakura, Shigeru Watanabe, Saori Yamamori, Yuuki Iida, Masanori Saito, Hitoshi Miyaoka, Masami Takahash. Dual mechanisms of rapid expression of anxiety-related behavior in pilocarpine-treated epileptic mice. Epilepsy research. vol 123. 2017-12-15. PMID:27132018. |
a mouse model of epilepsy was generated by inducing status epilepticus (se) for either 1.5 or 4.5h with pilocarpine to study anxiety-related behaviors, changes in the electroencephalogram of the cerebral cortex and hippocampus, and expression of hippocampal proteins. |
2017-12-15 |
2023-08-13 |
mouse |
| Flávia Doná, Isaltino Marcelo Conceição, Henning Ulrich, Eliane Beraldi Ribeiro, Thalma Ariani Freitas, Ana Leonor Abrahao Nencioni, Maria José da Silva Fernande. Variations of ATP and its metabolites in the hippocampus of rats subjected to pilocarpine-induced temporal lobe epilepsy. Purinergic signalling. vol 12. issue 2. 2017-11-09. PMID:26939579. |
we have used a rat model of temporal lobe epilepsy induced by pilocarpine to study the dynamics of purine metabolism in the hippocampus during different times of status epilepticus (se) and the chronic phase. |
2017-11-09 |
2023-08-13 |
rat |
| Hafiz Mawasi, David Bibi, Tawfeeq Shekh-Ahmad, Chanan Shaul, Simcha Blotnik, Meir Biale. Pharmacokinetic-Pharmacodynamic Correlation and Brain Penetration of sec-Butylpropylacetamide, a New CNS Drug Possessing Unique Activity against Status Epilepticus. Molecular pharmaceutics. vol 13. issue 7. 2017-10-20. PMID:27218460. |
spd possess a wide-spectrum anticonvulsant profile better than that of vpa and blocks status epilepticus (se) induced by pilocarpine and organophosphates. |
2017-10-20 |
2023-08-13 |
rat |
| b' Jo\\xc3\\xa3o Paulo Lopes Born, Heloisa de Carvalho Matos, Mykaella Andrade de Araujo, Olagide Wagner Castro, Marcelo Duzzioni, Jos\\xc3\\xa9 Eduardo Peixoto-Santos, Jo\\xc3\\xa3o Pereira Leite, Norberto Garcia-Cairasco, Maria Luisa Pa\\xc3\\xa7\\xc3\\xb3-Larson, Daniel Leite G\\xc3\\xb3es Gita\\xc3\\xa. Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process. PloS one. vol 12. issue 8. 2017-10-06. PMID:28783762.' |
given that postmortem changes in several gene transcripts could impact the detection of changes in case-control studies, we evaluated the effect of using autopsy specimens with different postmortem intervals (pmi) on differential gene expression of the pilocarpine (pilo)induced status epilepticus (se) of mtle. |
2017-10-06 |
2023-08-13 |
rat |
| Raquel Araujo Do Val-da Silva, José Eduardo Peixoto-Santos, Renata Caldo Scandiuzzi, Priscila Alves Balista, Mirian Bassi, Mogens Lesner Glass, Rodrigo Neves Romcy-Pereira, Orfa Yineth Galvis-Alonso, João Pereira Leit. Decreased neuron loss and memory dysfunction in pilocarpine-treated rats pre-exposed to hypoxia. Neuroscience. vol 332. 2017-09-05. PMID:27373771. |
in this study, we investigated the chronic effects of hypoxic preconditioning on spontaneous recurrent seizures (srs), neuronal death, and spatial memory performance in rats subjected to pilocarpine (pilo)-induced status epilepticus (se). |
2017-09-05 |
2023-08-13 |
rat |
| Beatriz Oliveira Amorim, Clement Hamani, Elenn Ferreira, Maísa Ferreira Miranda, Maria José S Fernandes, Antonio M Rodrigues, Antônio-Carlos G de Almeida, Luciene Covola. Effects of A1 receptor agonist/antagonist on spontaneous seizures in pilocarpine-induced epileptic rats. Epilepsy & behavior : E&B. vol 61. 2017-08-17. PMID:27371881. |
a1 receptor agonists increase the latency for the development of seizures and status epilepticus following pilocarpine administration. |
2017-08-17 |
2023-08-13 |
rat |
| Rebecca Brulet, Jingfei Zhu, Mahafuza Aktar, Jenny Hsieh, Kyung-Ok Ch. Mice with conditional NeuroD1 knockout display reduced aberrant hippocampal neurogenesis but no change in epileptic seizures. Experimental neurology. vol 293. 2017-08-17. PMID:28427858. |
wild-type mice treated with pilocarpine to induce status epilepticus (se) showed a significant up-regulation of neurod1+ immature neuroblasts located in both the granule cell layer (gcl), and ectopically localized to the hilar region of the hippocampus. |
2017-08-17 |
2023-08-13 |
mouse |
| Jesús-Servando Medel-Matus, Don Shin, Raman Sankar, Andrey Mazarat. Inherent vulnerabilities in monoaminergic pathways predict the emergence of depressive impairments in an animal model of chronic epilepsy. Epilepsia. vol 58. issue 8. 2017-08-17. PMID:28597913. |
the assays were performed before and 2 months after pilocarpine status epilepticus. |
2017-08-17 |
2023-08-13 |
human |
| Igor S Melo, Yngrid M O Santos, Maísa A Costa, Amanda L D Pacheco, Nívea K G T Silva, L Cardoso-Sousa, U P Pereira, L R Goulart, Norberto Garcia-Cairasco, Marcelo Duzzioni, Daniel L G Gitaí, Cristiane Q Tilelli, Robinson Sabino-Silva, Olagide W Castr. Inhibition of sodium glucose cotransporters following status epilepticus induced by intrahippocampal pilocarpine affects neurodegeneration process in hippocampus. Epilepsy & behavior : E&B. vol 61. 2017-08-15. PMID:27429292. |
inhibition of sodium glucose cotransporters following status epilepticus induced by intrahippocampal pilocarpine affects neurodegeneration process in hippocampus. |
2017-08-15 |
2023-08-13 |
rat |
| Pei-Lu Yi, Shuo-Bin Jou, Yi-Jou Wu, Fang-Chia Chan. Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture. Journal of visualized experiments : JoVE. issue 118. 2017-08-11. PMID:28060294. |
intraperitoneal (ip) injection of pilocarpine induces generalized epilepsy and status epilepticus (se) in rats. |
2017-08-11 |
2023-08-13 |
mouse |
| Qian-Qian Wang, Li-Jun Zhu, Xian-Hong Wang, Jian Zuo, Hui-Yan He, Miao-Miao Tian, Lei Wang, Gui-Ling Liang, Yu Wan. Chronic Trigeminal Nerve Stimulation Protects Against Seizures, Cognitive Impairments, Hippocampal Apoptosis, and Inflammatory Responses in Epileptic Rats. Journal of molecular neuroscience : MN. vol 59. issue 1. 2017-03-10. PMID:26973056. |
rats were injected with pilocarpine to produce status epilepticus (se) and the following chronic epilepsy. |
2017-03-10 |
2023-08-13 |
rat |
| Hui Shao, Yang Yang, Ai-Ping Qi, Pian Hong, Guang-Xi Zhu, Xin-Yu Cao, Wei-Gang Ji, Zhi-Ru Zh. Gastrodin Reduces the Severity of Status Epilepticus in the Rat Pilocarpine Model of Temporal Lobe Epilepsy by Inhibiting Nav1.6 Sodium Currents. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27743286. |
gastrodin reduces the severity of status epilepticus in the rat pilocarpine model of temporal lobe epilepsy by inhibiting nav1.6 sodium currents. |
2017-03-07 |
2023-08-13 |
rat |
| Ruohan Li, Limin Ma, Hao Huang, Shu Ou, Jinxian Yuan, Tao Xu, Xinyuan Yu, Xi Liu, Juan Yang, Yangmei Chen, Xi Pen. Altered Expression of CXCL13 and CXCR5 in Intractable Temporal Lobe Epilepsy Patients and Pilocarpine-Induced Epileptic Rats. Neurochemical research. vol 42. issue 2. 2017-03-07. PMID:27873133. |
further, cxcl13 and cxcr5 protein levels were altered during the different epileptic phases after onset of status epilepticus (se) in the pilocarpine model rats, including the acute phase (6, 24, and 72 h), latent phase (7 and 14 days) and chronic phase (30 and 60 days groups). |
2017-03-07 |
2023-08-13 |
rat |
| Chandra Bhushan Mishra, Shikha Kumari, Manisha Tiwar. Design and synthesis of some new 1-phenyl-3/4-[4-(aryl/heteroaryl/alkyl-piperazine1-yl)-phenyl-ureas as potent anticonvulsant and antidepressant agents. Archives of pharmacal research. vol 39. issue 5. 2017-02-07. PMID:26891908. |
in addition, this compound also showed considerable protection against pilocarpine induced status epilepticus in rats. |
2017-02-07 |
2023-08-13 |
rat |
| Erika R Kinjo, Guilherme S V Higa, Bianca A Santos, Erica de Sousa, Marcio V Damico, Lais T Walter, Edgard Morya, Angela C Valle, Luiz R G Britto, Alexandre H Kihar. Pilocarpine-induced seizures trigger differential regulation of microRNA-stability related genes in rat hippocampal neurons. Scientific reports. vol 6. 2016-12-26. PMID:26869208. |
herein, we confirmed that pilocarpine application promptly (<30 min) induces status epilepticus (se) as revealed by changes in rat electrocorticogram particularly in fast-beta range (21-30 hz). |
2016-12-26 |
2023-08-13 |
rat |