| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christin M Godale, Emma V Parkins, Christina Gross, Steve C Danze. Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus. Journal of molecular neuroscience : MN. 2022-05-26. PMID:35618880. |
raptor or rictor was deleted from roughly 25% of hippocampal granule cells, with variable involvement of other hippocampal neurons, after pilocarpine status epilepticus. |
2022-05-26 |
2023-08-13 |
mouse |
| J Dal Pai, J C da Silva, V Sanabria, R P Amorim, G Predebon, A C Cossa, E Trindade-Filho, D Amad. Non-Status Epilepticus female rats show seizure-like behaviors in the chronic phase of Pilocarpine experimental model. Brazilian journal of biology = Revista brasleira de biologia. vol 83. 2022-01-26. PMID:35081234. |
only few studies have focus on animals that received pilocarpine (pilo) and did not develop behavioral status epilepticus (se) and, whether they may become epileptic in the model's chronic phase. |
2022-01-26 |
2023-08-13 |
rat |
| Francesca Mengoni, Valentina Salari, Inna Kosenkova, Grygoriy Tsenov, Massimo Donadelli, Giovanni Malerba, Giuseppe Bertini, Federico Del Gallo, Paolo Francesco Faben. Gut microbiota modulates seizure susceptibility. Epilepsia. vol 62. issue 9. 2021-12-09. PMID:34324703. |
our results provide the first evidence that mice who received microbiota from epileptic animals are more prone to develop status epilepticus, compared to recipients of "healthy" microbiota, after a subclinical dose of pilocarpine, indicating a higher susceptibility to seizures. |
2021-12-09 |
2023-08-13 |
mouse |
| Alexandre Vigier, Nicolas Partouche, François J Michel, Valérie Crépel, Thomas Marissa. Substantial outcome improvement using a refined pilocarpine mouse model of temporal lobe epilepsy. Neurobiology of disease. vol 161. 2021-12-07. PMID:34752924. |
however, the traditional pilocarpine injection protocol using mice was associated with a high death rate, possibly because of cardiorespiratory collapse following status epilepticus (se). |
2021-12-07 |
2023-08-13 |
mouse |
| Esther Pototskiy, Katherine Vinokuroff, Andrew Ojeda, C Kendall Major, Deepak Sharma, Taylor Anderson, Kendall Howard, Ronen Borenstein, Alberto E Must. Downregulation of CD40L-CD40 attenuates seizure susceptibility and severity of seizures. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34446808. |
cd40 deficient mice (cd40ko) and control mice (wild type, wt) received pentenyltetrazole (ptz) or pilocarpine to evaluate seizures and status epilepticus (se) respectively. |
2021-11-08 |
2023-08-13 |
mouse |
| Rilang Lv, Xiaoyun Xu, Zheng Luo, Nan Shen, Feng Wang, Yongbo Zha. Pyrrolidine dithiocarbamate (PDTC) inhibits the overexpression of MCP-1 and attenuates microglial activation in the hippocampus of a pilocarpine-induced status epilepticus rat model. Experimental and therapeutic medicine. vol 7. issue 1. 2021-10-21. PMID:24348761. |
the aim of this study was to investigate the effects of pyrrolidine dithiocarbamate (pdtc) on mcp-1 expression and microglial activation in the hippocampus of a rat model of pilocarpine (pilo)-induced status epilepticus (se). |
2021-10-21 |
2023-08-12 |
rat |
| Maxime Lévesque, Giuseppe Biagini, Marco de Curtis, Vadym Gnatkovsky, Julika Pitsch, Siyan Wang, Massimo Avol. The pilocarpine model of mesial temporal lobe epilepsy: Over one decade later, with more rodent species and new investigative approaches. Neuroscience and biobehavioral reviews. vol 130. 2021-10-20. PMID:34437936. |
fundamental work on the mechanisms leading to focal epileptic discharges in mesial temporal lobe epilepsy (mtle) often rests on the use of rodent models in which an initial status epilepticus (se) is induced by kainic acid or pilocarpine. |
2021-10-20 |
2023-08-13 |
mouse |
| Sree Lalitha Bojja, Bikash Medhi, Shashi Anand, Alka Bhatia, Rupa Joshi, Ranjana W Min. Metformin ameliorates the status epilepticus- induced hippocampal pathology through possible mTOR modulation. Inflammopharmacology. vol 29. issue 1. 2021-10-19. PMID:33386490. |
status epilepticus (se) was induced in male wistar rats with systemic administration of lithium (127 mg/kg) and pilocarpine (30 mg/kg). |
2021-10-19 |
2023-08-13 |
rat |
| Zaquer Suzana Munhoz Costa-Ferro, Gutierre Neves de Oliveira, Daniele Vieira da Silva, Daniel Rodrigo Marinowic, Denise Cantarelli Machado, Beatriz Monteiro Longo, Jaderson Costa da Cost. Intravenous infusion of bone marrow mononuclear cells promotes functional recovery and improves impaired cognitive function via inhibition of Rho guanine nucleotide triphosphatases and inflammatory signals in a model of chronic epilepsy. Brain structure & function. vol 225. issue 9. 2021-09-28. PMID:33128125. |
the latter had status epilepticus (se) induced through pilocarpine intraperitoneal injection. |
2021-09-28 |
2023-08-13 |
rat |
| Tanya S McDonald, Elliott S Neal, Karin Borge. Fructose 1,6-bisphosphate is anticonvulsant and improves oxidative glucose metabolism within the hippocampus and liver in the chronic pilocarpine mouse epilepsy model. Epilepsy & behavior : E&B. vol 122. 2021-09-15. PMID:34388666. |
two weeks after the pilocarpine injections, mice that experienced status epilepticus (se, "epileptic") and did not experience se (no se, "nonepileptic") were injected with vehicle (0.9% saline) or f16bp (1 g/kg in 0.9% saline) daily for 5 consecutive days. |
2021-09-15 |
2023-08-13 |
mouse |
| Natsu Sasaki-Takahashi, Hiroshi Shinohara, Seiji Shioda, Tatsunori Sek. The polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: Study using an improved mouse pilocarpine model of epilepsy. Hippocampus. vol 30. issue 3. 2021-09-13. PMID:32101365. |
the polarity and properties of radial glia-like neural stem cells are altered by seizures with status epilepticus: study using an improved mouse pilocarpine model of epilepsy. |
2021-09-13 |
2023-08-13 |
mouse |
| Benjamin Owen, Edyta Bichler, Morris Benvenist. Excitatory synaptic transmission in hippocampal area CA1 is enhanced then reduced as chronic epilepsy progresses. Neurobiology of disease. vol 154. 2021-09-02. PMID:33753293. |
in rats injected with pilocarpine, status epilepticus ensued. |
2021-09-02 |
2023-08-13 |
rat |
| Aleksandra Szewczyk, Mirosław Zagaja, Joanna Szala-Rycaj, Maciej Maj, Marta Andres-Mac. Effect of Lacosamide and Ethosuximide Chronic Treatment on Neural Precursor Cells and Cognitive Functions after Pilocarpine Induced Status Epilepticus in Mice. Brain sciences. vol 11. issue 8. 2021-08-30. PMID:34439633. |
effect of lacosamide and ethosuximide chronic treatment on neural precursor cells and cognitive functions after pilocarpine induced status epilepticus in mice. |
2021-08-30 |
2023-08-13 |
mouse |
| Tomohiro Ohgomori, Shozo Jinn. Modulation of neuropathology and cognitive deficits by lipopolysaccharide preconditioning in a mouse pilocarpine model of status epilepticus. Neuropharmacology. vol 176. 2021-08-13. PMID:32634527. |
modulation of neuropathology and cognitive deficits by lipopolysaccharide preconditioning in a mouse pilocarpine model of status epilepticus. |
2021-08-13 |
2023-08-13 |
mouse |
| Andrea Verónica Enrique, Mauricio Emiliano Di Ianni, Sofía Goicoechea, Alberto Lazarowski, María Guadalupe Valle-Dorado, Juan José López Costa, Luisa Rocha, Elena Girardi, Alan Talev. New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice. Epilepsy & behavior : E&B. vol 121. issue Pt B. 2021-08-11. PMID:31420290. |
furthermore, pretreatment with sa in the pilocarpine status epilepticus (se) model resulted in decreased histamine release in comparison with nontreated animals. |
2021-08-11 |
2023-08-13 |
mouse |
| Doodipala Samba Reddy, Marcus Zaayman, Ramkumar Kuruba, Xin W. Comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, DFP, and soman. Neuropharmacology. vol 191. 2021-06-23. PMID:33878303. |
comparative profile of refractory status epilepticus models following exposure of cholinergic agents pilocarpine, dfp, and soman. |
2021-06-23 |
2023-08-13 |
rat |
| Xian-Lian Deng, Li Feng, Zi-Xin Wang, Yue-E Zhao, Qiong Zhan, Xiao-Mei Wu, Bo Xiao, Yi Sh. The Runx1/Notch1 Signaling Pathway Participates in M1/M2 Microglia Polarization in a Mouse Model of Temporal Lobe Epilepsy and in BV-2 Cells. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32632543. |
in the present study, we first found that in a male mouse model of tle induced by pilocarpine, flow cytometry revealed a time-dependent m2-to-m1 microglial transition after status epilepticus. |
2021-06-08 |
2023-08-13 |
mouse |
| Silvia Regina Bica Kohek, Maira Licia Foresti, Miriam Marcela Blanco, Clarissa Fantin Cavarsan, Clivandir Severino da Silva, Luiz E Mell. Anxious Profile Influences Behavioral and Immunohistological Findings in the Pilocarpine Model of Epilepsy. Frontiers in pharmacology. vol 12. 2021-05-26. PMID:34025410. |
in addition, animals that were injected with pilocarpine, but did not develop status epilepticus, had behavioral and neuroanatomical alterations as compared to control animals, indicating its importance as an additional tool for investigating the heterogeneity of the epileptogenic response after an initial insult. |
2021-05-26 |
2023-08-13 |
Not clear |
| Daniele Suzete Persike, Rebeca Padrão Amorim Puccinelli, Maria José da Silva Fernande. Adenosine A1 Receptor Agonist (R-PIA) before Pilocarpine Modulates Pro- and Anti-Apoptotic Factors in an Animal Model of Epilepsy. Pharmaceuticals (Basel, Switzerland). vol 14. issue 4. 2021-05-18. PMID:33919533. |
r-pia was injected before pilocarpine (pilo), and four groups were studied at 1 h 30 min and 7 days following initiation of status epilepticus (se): pilo, r-pia+pilo, saline, and r-pia+saline. |
2021-05-18 |
2023-08-13 |
rat |
| Muhammad Nauman Arshad, Janice R Naegel. Induction of Temporal Lobe Epilepsy in Mice with Pilocarpine. Bio-protocol. vol 10. issue 4. 2021-05-04. PMID:33654757. |
in the pilocarpine model of temporal lobe epilepsy (tle) in rodents, systemic injections of pilocarpine induce continuous, prolonged limbic seizures, a condition termed "status epilepticus" (se). |
2021-05-04 |
2023-08-13 |
mouse |