| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hua-Jun Feng, Gregory C Mathews, Chris Kao, Robert L Macdonal. Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus. Journal of neurophysiology. vol 99. issue 3. 2008-06-12. PMID:18216225. |
partial limbic seizures in rodents induced by pilocarpine progress from stages i-ii (mouth and facial movements; head nodding) to stage iii (forelimb clonus) and then progress rapidly to stages iv-v (generalized limbic seizures; rearing, and rearing with falling) followed by status epilepticus (se). |
2008-06-12 |
2023-08-12 |
rat |
| Cristiano R Jesse, Lucielli Savegnago, Joao B T Rocha, Cristina W Nogueir. Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats. Brain research. vol 1198. 2008-06-02. PMID:18242586. |
this study was designed to verify the influence of mpep (2-methyl-6-phenylethynyl pyridine hydrochloride), an antagonist of metabotropic glutamate receptor subtype 5 (mglur5), in seizures and status epilepticus (se) induced by pilocarpine in young rats. |
2008-06-02 |
2023-08-12 |
rat |
| Björn Bauer, Anika M S Hartz, Anton Pekcec, Kathrin Toellner, David S Miller, Heidrun Potschk. Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling. Molecular pharmacology. vol 73. issue 5. 2008-05-06. PMID:18094072. |
moreover, using a pilocarpine status epilepticus rat model, we observed seizure-induced increases in capillary p-glycoprotein expression that were attenuated by administration of indomethacin, a cox inhibitor. |
2008-05-06 |
2023-08-12 |
mouse |
| Clement Hamani, Mojgan Hodaie, Jason Chiang, Martin del Campo, Danielle M Andrade, David Sherman, Marek Mirski, Luiz E Mello, Andres M Lozan. Deep brain stimulation of the anterior nucleus of the thalamus: effects of electrical stimulation on pilocarpine-induced seizures and status epilepticus. Epilepsy research. vol 78. issue 2-3. 2008-04-23. PMID:18083005. |
as the optimal stimulation settings remain elusive, we studied the effects of different stimulation parameters against pilocarpine induced seizures and status epilepticus (se). |
2008-04-23 |
2023-08-12 |
Not clear |
| L Uva, L Librizzi, N Marchi, F Noe, R Bongiovanni, A Vezzani, D Janigro, M de Curti. Acute induction of epileptiform discharges by pilocarpine in the in vitro isolated guinea-pig brain requires enhancement of blood-brain barrier permeability. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18082973. |
systemic application of the muscarinic agonist, pilocarpine, is commonly utilized to induce an acute status epilepticus that evolves into a chronic epileptic condition characterized by spontaneous seizures. |
2008-04-22 |
2023-08-12 |
Not clear |
| L Uva, L Librizzi, N Marchi, F Noe, R Bongiovanni, A Vezzani, D Janigro, M de Curti. Acute induction of epileptiform discharges by pilocarpine in the in vitro isolated guinea-pig brain requires enhancement of blood-brain barrier permeability. Neuroscience. vol 151. issue 1. 2008-04-22. PMID:18082973. |
recent findings suggest that the status epilepticus induced by pilocarpine may be triggered by changes in the blood-brain barrier (bbb) permeability. |
2008-04-22 |
2023-08-12 |
Not clear |
| Lúcia F L Santos, Rizângela L M Freitas, Sarah M L Xavier, Gláucio B Saldanha, Rivelilson M Freita. Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. Pharmacology, biochemistry, and behavior. vol 89. issue 1. 2008-04-09. PMID:18096215. |
our results can suggest that neuroprotective effects of vitamin c in adult rats can be the result of reduced lipid peroxidation levels and increase of catalase activity after seizures and status epilepticus induced by pilocarpine. |
2008-04-09 |
2023-08-12 |
rat |
| Feng Ru Tang, Peng Min Chen, Yong Cheng Tang, Mui Chiung Tsai, Wei Ling Le. Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: a novel approach for controlling status epilepticus. Neuropharmacology. vol 53. issue 7. 2008-02-25. PMID:17904168. |
by intravenous administration of group i metabotropic glutamate receptor antagonists at 1 or 2h during pilocarpine induced status epilepticus (pise), we showed that mglur1 antagonists aida or ly367385 (at dosages ranging from 25 to 200mg/kg), mglur5 antagonists sib1757 (at dosages ranging from 25 to 200mg/kg), sib1893 (from 25 to 100mg/kg), mpep (from 25 to 100mg/kg) injected at 1 or 2h during pise were ineffective in controlling status epilepticus (se). |
2008-02-25 |
2023-08-12 |
mouse |
| M R Winawer, N Makarenko, D P McCloskey, T M Hintz, N Nair, A A Palmer, H E Scharfma. Acute and chronic responses to the convulsant pilocarpine in DBA/2J and A/J mice. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17904758. |
these strains were compared using the chemoconvulsant pilocarpine, because pilocarpine induces status epilepticus, a state of severe, prolonged seizures. |
2008-01-16 |
2023-08-12 |
mouse |
| Ina Gröticke, Katrin Hoffmann, Wolfgang Lösche. Behavioral alterations in the pilocarpine model of temporal lobe epilepsy in mice. Experimental neurology. vol 207. issue 2. 2008-01-08. PMID:17714705. |
in order to ensure the occurrence of status epilepticus (se) and decrease mortality, individual dosing of pilocarpine was performed by ramping up the dose until onset of se. |
2008-01-08 |
2023-08-12 |
mouse |
| Nicola Marchi, Emily Oby, Ayush Batra, Laura Uva, Marco De Curtis, Nadia Hernandez, Anette Van Boxel-Dezaire, Imad Najm, Damir Janigr. In vivo and in vitro effects of pilocarpine: relevance to ictogenesis. Epilepsia. vol 48. issue 10. 2007-11-13. PMID:17645533. |
a common experimental model of status epilepticus (se) utilizes intraperitoneal administration of the cholinergic agonist pilocarpine preceded by methyl-scopolamine treatment. |
2007-11-13 |
2023-08-12 |
Not clear |
| Joseph P Pierce, Michael Punsoni, Daniel P McCloskey, Helen E Scharfma. Mossy cell axon synaptic contacts on ectopic granule cells that are born following pilocarpine-induced seizures. Neuroscience letters. vol 422. issue 2. 2007-10-29. PMID:17611032. |
pilocarpine was administered to adult male rats, and those which developed status epilepticus were perfused 5-7 months later, after the period of egc genesis. |
2007-10-29 |
2023-08-12 |
rat |
| M B Pereira, R L M Freitas, M A G Assis, R F Silva, M M F Fonteles, R M Freitas, R N Takahash. Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats. Neuroscience letters. vol 419. issue 3. 2007-09-28. PMID:17499921. |
study pharmacologic of the gabaergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult wistar rats. |
2007-09-28 |
2023-08-12 |
rat |
| M B Pereira, R L M Freitas, M A G Assis, R F Silva, M M F Fonteles, R M Freitas, R N Takahash. Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats. Neuroscience letters. vol 419. issue 3. 2007-09-28. PMID:17499921. |
this work was designed to study the influence of drugs during seizures and status epilepticus (se) induced by pilocarpine and mortality in adult rats. |
2007-09-28 |
2023-08-12 |
rat |
| Nicholas D E Greene, Abiodun Bamidele, ManKin Choy, Sandra C P de Castro, Robin Wait, Kit-Yi Leung, Shajna Begum, David G Gadian, Rod C Scott, Mark F Lythgo. Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus. Proteomics. vol 7. issue 8. 2007-07-23. PMID:17366478. |
the lithium pilocarpine model of status epilepticus (se) in the rat provides a model in which to investigate the molecular and pathogenic process leading to hippocampal damage. |
2007-07-23 |
2023-08-12 |
human |
| Yoel Yaari, Cuiyong Yue, Hailing S. Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis. The Journal of physiology. vol 580. issue Pt. 2. 2007-07-19. PMID:17272342. |
a single episode of status epilepticus (se) induced in rodents by the convulsant pilocarpine, produces, after a latent period of > or = 2 weeks, a chronic epileptic condition. |
2007-07-19 |
2023-08-12 |
cat |
| Karolien Goffin, Jari Nissinen, Koen Van Laere, Asla Pitkäne. Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. Experimental neurology. vol 205. issue 2. 2007-07-10. PMID:17442304. |
pilocarpine administration to rats results in status epilepticus (se) and after a latency period to the occurrence of spontaneous seizures. |
2007-07-10 |
2023-08-12 |
rat |
| D O Barros, S M L Xavier, C O Barbosa, R F Silva, R L M Freitas, F D Maia, A A Oliveira, R M Freitas, R N Takahash. Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Neuroscience letters. vol 416. issue 3. 2007-07-06. PMID:17383094. |
effects of the vitamin e in catalase activities in hippocampus after status epilepticus induced by pilocarpine in wistar rats. |
2007-07-06 |
2023-08-12 |
rat |
| D O Barros, S M L Xavier, C O Barbosa, R F Silva, R L M Freitas, F D Maia, A A Oliveira, R M Freitas, R N Takahash. Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Neuroscience letters. vol 416. issue 3. 2007-07-06. PMID:17383094. |
neurochemical studies have proposed a role for catalase in brain mechanisms responsible by development to status epilepticus (se) induced by pilocarpine. |
2007-07-06 |
2023-08-12 |
rat |
| Feng Li Jiang, Yong Cheng Tang, Shwn Chin Chia, Therese M Jay, Feng Ru Tan. Anticonvulsive effect of a selective mGluR8 agonist (S)-3,4-dicarboxyphenylglycine (S-3,4-DCPG) in the mouse pilocarpine model of status epilepticus. Epilepsia. vol 48. issue 4. 2007-07-06. PMID:17430409. |
anticonvulsive effect of a selective mglur8 agonist (s)-3,4-dicarboxyphenylglycine (s-3,4-dcpg) in the mouse pilocarpine model of status epilepticus. |
2007-07-06 |
2023-08-12 |
mouse |