| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Osamu Yokota, Seishi Terada, Takeshi Ishihara, Hanae Nakashima, Aki Kugo, Hiroshi Ujike, Kuniaki Tsuchiya, Kenji Ikeda, Yuko Saito, Shigeo Murayama, Hideki Ishizu, Shigetoshi Kurod. Neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, in the hippocampus of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 4. 2004-10-18. PMID:15276698. |
neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, in the hippocampus of patients with schizophrenia. |
2004-10-18 |
2023-08-12 |
Not clear |
| Osamu Yokota, Seishi Terada, Takeshi Ishihara, Hanae Nakashima, Aki Kugo, Hiroshi Ujike, Kuniaki Tsuchiya, Kenji Ikeda, Yuko Saito, Shigeo Murayama, Hideki Ishizu, Shigetoshi Kurod. Neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, in the hippocampus of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 4. 2004-10-18. PMID:15276698. |
to clarify whether or not cox-2 expression is altered in schizophrenia, we examined neuronal cox-2 expression in the hippocampus from cases of schizophrenia (n = 17), normal controls (n = 22), and cases of alzheimer's disease (ad) as a positive control (n = 17). |
2004-10-18 |
2023-08-12 |
Not clear |
| Osamu Yokota, Seishi Terada, Takeshi Ishihara, Hanae Nakashima, Aki Kugo, Hiroshi Ujike, Kuniaki Tsuchiya, Kenji Ikeda, Yuko Saito, Shigeo Murayama, Hideki Ishizu, Shigetoshi Kurod. Neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, in the hippocampus of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 4. 2004-10-18. PMID:15276698. |
in contrast, cox-2 expression was not up-regulated in any subdivision of the hippocampus in the schizophrenia group. |
2004-10-18 |
2023-08-12 |
Not clear |
| Michael F Egan, Richard E Straub, Terry E Goldberg, Imtiaz Yakub, Joseph H Callicott, Ahmad R Hariri, Venkata S Mattay, Alessandro Bertolino, Thomas M Hyde, Cynthia Shannon-Weickert, Mayada Akil, Jeremy Crook, Radha Krishna Vakkalanka, Rishi Balkissoon, Richard A Gibbs, Joel E Kleinman, Daniel R Weinberge. Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 34. 2004-10-18. PMID:15310849. |
these convergent data point to a specific molecular pathway by which grm3 genotype alters glutamate neurotransmission, prefrontal and hippocampal physiology and cognition, and thereby increased risk for schizophrenia. |
2004-10-18 |
2023-08-12 |
human |
| Morris B Goldman, Colin P Mitchel. What is the functional significance of hippocampal pathology in schizophrenia? Schizophrenia bulletin. vol 30. issue 2. 2004-10-08. PMID:15279054. |
what is the functional significance of hippocampal pathology in schizophrenia? |
2004-10-08 |
2023-08-12 |
Not clear |
| Barbara K Lipsk. Using animal models to test a neurodevelopmental hypothesis of schizophrenia. Journal of psychiatry & neuroscience : JPN. vol 29. issue 4. 2004-10-05. PMID:15309044. |
a series of studies has shown that neonatal excitotoxic disconnection of the rat ventral hippocampus may serve as a heuristic model of schizophrenia. |
2004-10-05 |
2023-08-12 |
rat |
| Barbara K Lipsk. Using animal models to test a neurodevelopmental hypothesis of schizophrenia. Journal of psychiatry & neuroscience : JPN. vol 29. issue 4. 2004-10-05. PMID:15309044. |
our data suggest that neonatal disconnection of the ventral hippocampus alters development and plasticity of prefrontal cortical circuitry and produces a constellation of behavioural and cellular changes that mimic many aspects of schizophrenia. |
2004-10-05 |
2023-08-12 |
rat |
| Barbara K Lipsk. Using animal models to test a neurodevelopmental hypothesis of schizophrenia. Journal of psychiatry & neuroscience : JPN. vol 29. issue 4. 2004-10-05. PMID:15309044. |
the neonatal hippocampal disconnection model represents a potential new model of schizophrenia without a gross anatomical lesion. |
2004-10-05 |
2023-08-12 |
rat |
| Paul Yushkevich, Sarang Joshi, Stephen M Pizer, John G Csernansky, Lei E Wan. Feature selection for shape-based classification of biological objects. Information processing in medical imaging : proceedings of the ... conference. vol 18. 2004-10-01. PMID:15344451. |
the new method is tested on synthetic data and on clinical data from a study of hippocampal shape in schizophrenia. |
2004-10-01 |
2023-08-12 |
Not clear |
| R Andrew Chambers, Jane R Taylo. Animal modeling dual diagnosis schizophrenia: sensitization to cocaine in rats with neonatal ventral hippocampal lesions. Biological psychiatry. vol 56. issue 5. 2004-09-30. PMID:15336512. |
animal modeling dual diagnosis schizophrenia: sensitization to cocaine in rats with neonatal ventral hippocampal lesions. |
2004-09-30 |
2023-08-12 |
rat |
| H Ehrenreich, D Degner, J Meller, M Brines, M Béhé, M Hasselblatt, H Woldt, P Falkai, F Knerlich, S Jacob, N von Ahsen, W Maier, W Brück, E Rüther, A Cerami, W Becker, A-L Siré. Erythropoietin: a candidate compound for neuroprotection in schizophrenia. Molecular psychiatry. vol 9. issue 1. 2004-09-27. PMID:14581931. |
using rodent studies, primary hippocampal neurons in culture, immunohistochemical analysis of human post-mortem brain tissue and nuclear imaging technology in man, we demonstrate that: (1) peripherally applied recombinant human (rh) epo penetrates into the brain efficiently both in rat and humans, (2) rhepo is enriched intracranially in healthy men and more distinctly in schizophrenic patients, (3) epo receptors are densely expressed in hippocampus and cortex of schizophrenic subjects but distinctly less in controls, (4) rhepo attenuates the haloperidol-induced neuronal death in vitro, and (4) peripherally administered rhepo enhances cognitive functioning in mice in the context of an aversion task involving cortical and subcortical pathways presumably affected in schizophrenia. |
2004-09-27 |
2023-08-12 |
mouse |
| G Keilhoff, A Becker, G Grecksch, G Wolf, H-G Bernstei. Repeated application of ketamine to rats induces changes in the hippocampal expression of parvalbumin, neuronal nitric oxide synthase and cFOS similar to those found in human schizophrenia. Neuroscience. vol 126. issue 3. 2004-09-14. PMID:15183509. |
repeated application of ketamine to rats induces changes in the hippocampal expression of parvalbumin, neuronal nitric oxide synthase and cfos similar to those found in human schizophrenia. |
2004-09-14 |
2023-08-12 |
human |
| Brian Dea. [3H]RX 821002 in human dorsolateral prefrontal cortex: no changes in postmortem tissue from subjects with schizophrenia. Psychiatry research. vol 119. issue 1-2. 2004-08-24. PMID:12860357. |
these data add to those of one other study that showed the alpha(2)-adrenoreceptors were not altered in brodmann's area 10 and the hippocampus from subjects with schizophrenia, and do not support the hypothesis that changes in alpha(2)-adrenoreceptors are a marker for treatment resistance in schizophrenia. |
2004-08-24 |
2023-08-12 |
human |
| Jong-Min Lee, Sun Hyung Kim, Dong Pyo Jang, Tae Hyon Ha, Jae-Jin Kim, In Young Kim, Jun Soo Kwon, Sun I Ki. Deformable model with surface registration for hippocampal shape deformity analysis in schizophrenia. NeuroImage. vol 22. issue 2. 2004-08-19. PMID:15193612. |
deformable model with surface registration for hippocampal shape deformity analysis in schizophrenia. |
2004-08-19 |
2023-08-12 |
Not clear |
| Larry J Seidman, Christos Pantelis, Matcheri S Keshavan, Stephen V Faraone, Jill M Goldstein, Nicholas J Horton, Nikos Makris, Peter Falkai, Verne S Caviness, Ming T Tsuan. A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric family study of the parahippocampal gyrus. Schizophrenia bulletin. vol 29. issue 4. 2004-08-13. PMID:14989416. |
medial temporal lobe (mtl), especially hippocampal, volume alterations are among the most robust brain vulnerabilities for schizophrenia. |
2004-08-13 |
2023-08-12 |
Not clear |
| Larry J Seidman, Christos Pantelis, Matcheri S Keshavan, Stephen V Faraone, Jill M Goldstein, Nicholas J Horton, Nikos Makris, Peter Falkai, Verne S Caviness, Ming T Tsuan. A review and new report of medial temporal lobe dysfunction as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric family study of the parahippocampal gyrus. Schizophrenia bulletin. vol 29. issue 4. 2004-08-13. PMID:14989416. |
because verbal declarative memory (vdm) deficits are prominent and the parahippocampal gyrus (phg) is considered to be centrally involved with the hippocampus in vdm processing, we analyzed phg data from a family study of schizophrenia. |
2004-08-13 |
2023-08-12 |
Not clear |
| Katherine L Narr, Paul M Thompson, Philip Szeszko, Delbert Robinson, Seonah Jang, Roger P Woods, Sharon Kim, Kiralee M Hayashi, Dina Asunction, Arthur W Toga, Robert M Bilde. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage. vol 21. issue 4. 2004-08-06. PMID:15050580. |
regional specificity of hippocampal volume reductions in first-episode schizophrenia. |
2004-08-06 |
2023-08-12 |
Not clear |
| Katherine L Narr, Paul M Thompson, Philip Szeszko, Delbert Robinson, Seonah Jang, Roger P Woods, Sharon Kim, Kiralee M Hayashi, Dina Asunction, Arthur W Toga, Robert M Bilde. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage. vol 21. issue 4. 2004-08-06. PMID:15050580. |
hippocampal volume reductions are widely observed in schizophrenia. |
2004-08-06 |
2023-08-12 |
Not clear |
| Katherine L Narr, Paul M Thompson, Philip Szeszko, Delbert Robinson, Seonah Jang, Roger P Woods, Sharon Kim, Kiralee M Hayashi, Dina Asunction, Arthur W Toga, Robert M Bilde. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage. vol 21. issue 4. 2004-08-06. PMID:15050580. |
using high-resolution mr images and novel computational image analysis methods, we identified the hippocampal subregions most vulnerable to disease processes in 62 (45 m/17 f) first-episode schizophrenia patients compared to 60 (30 m/30 f) healthy controls, similar in age. |
2004-08-06 |
2023-08-12 |
Not clear |
| Katherine L Narr, Paul M Thompson, Philip Szeszko, Delbert Robinson, Seonah Jang, Roger P Woods, Sharon Kim, Kiralee M Hayashi, Dina Asunction, Arthur W Toga, Robert M Bilde. Regional specificity of hippocampal volume reductions in first-episode schizophrenia. NeuroImage. vol 21. issue 4. 2004-08-06. PMID:15050580. |
significant bilateral hippocampal volume reductions were observed in schizophrenia irrespective of brain size corrections. |
2004-08-06 |
2023-08-12 |
Not clear |