| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Peleg-Raibstein, M A Pezze, B Ferger, W-N Zhang, C A Murphy, J Feldon, T Bas. Activation of dopaminergic neurotransmission in the medial prefrontal cortex by N-methyl-d-aspartate stimulation of the ventral hippocampus in rats. Neuroscience. vol 132. issue 1. 2005-07-20. PMID:15780480. |
moreover, it indicates that aberrant hippocampal activity, as found in neuropsychiatric diseases, such as schizophrenia and mood disorders, may contribute to disruption of certain cognitive and emotional functions which are extremely sensitive to imbalanced prefrontal dopamine transmission. |
2005-07-20 |
2023-08-12 |
rat |
| J Hauser, U Rudolph, R Keist, H Möhler, J Feldon, B K Ye. Hippocampal alpha5 subunit-containing GABAA receptors modulate the expression of prepulse inhibition. Molecular psychiatry. vol 10. issue 2. 2005-07-15. PMID:15263904. |
post-mortem analyses of schizophrenia brains have consistently revealed structural abnormalities of a developmental origin in the hippocampus. |
2005-07-15 |
2023-08-12 |
mouse |
| Natalya S Kolomeets, Diana D Orlovskaya, Valentina I Rachmanova, Natalya A Uranov. Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: a postmortem morphometric study. Synapse (New York, N.Y.). vol 57. issue 1. 2005-07-12. PMID:15858835. |
ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: a postmortem morphometric study. |
2005-07-12 |
2023-08-12 |
Not clear |
| François Laplante, Osamu Nakagawasai, Lalit K Srivastava, Rémi Quirio. Alterations in behavioral responses to a cholinergic agonist in post-pubertal rats with neonatal ventral hippocampal lesions: relationship to changes in muscarinic receptor levels. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 6. 2005-07-11. PMID:15637638. |
excitotoxic neonatal ventral hippocampal (nvh) lesion in rats is considered as a putative animal model of schizophrenia as lesioned animals show characteristic post-pubertal emergence of neurochemical and behavioral abnormalities analogous to some of those seen in this disease. |
2005-07-11 |
2023-08-12 |
rat |
| Nii A Addy, Ana Pocivavsek, Edward D Levi. Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 6. 2005-07-11. PMID:15688087. |
therapeutic treatment with clozapine in people with malfunctions of the hippocampus such as seen in schizophrenia may improve cognitive performance, whereas the same doses of clozapine may impair memory in individuals without hippocampal malfunction. |
2005-07-11 |
2023-08-12 |
rat |
| Henrik Ponten, Kirsten Sönniksen, Therése Abrahamsson, Nicholas Waters, Bengt Gustafsson, Eric Hanse, Laurent Gro. Behavioral and neurochemical repercussions of hippocampal network activity blockade during the neonatal period. Brain research. Developmental brain research. vol 155. issue 1. 2005-06-23. PMID:15763278. |
early destruction of the ventral hippocampus from postnatal day 7 (p7) has been shown to induce behavioral alterations in post-pubertal rats, similar to those observed in models for schizophrenia. |
2005-06-23 |
2023-08-12 |
rat |
| Heather C Strasser, Jessica Lilyestrom, Ebony R Ashby, Nancy A Honeycutt, David J Schretlen, Ann E Pulver, Ramona O Hopkins, J Raymond Depaulo, James B Potash, Barbara Schweizer, Khara O Yates, Elizabeth Kurian, Patrick E Barta, Godfrey D Pearlso. Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot study. Biological psychiatry. vol 57. issue 6. 2005-06-20. PMID:15780850. |
hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot study. |
2005-06-20 |
2023-08-12 |
human |
| Daphne J Holt, Anthony P Weiss, Scott L Rauch, Christopher I Wright, Martin Zalesak, Donald C Goff, Tali Ditman, Robert C Welsh, Stephan Hecker. Sustained activation of the hippocampus in response to fearful faces in schizophrenia. Biological psychiatry. vol 57. issue 9. 2005-06-13. PMID:15860342. |
sustained activation of the hippocampus in response to fearful faces in schizophrenia. |
2005-06-13 |
2023-08-12 |
Not clear |
| S L Eastwood, P J Harriso. Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia: further evidence for a synaptic pathology affecting glutamate neurons. Schizophrenia research. vol 73. issue 2-3. 2005-06-09. PMID:15653259. |
hippocampal vglut1 mrna declined with age selectively in the schizophrenia group. |
2005-06-09 |
2023-08-12 |
human |
| Mogens Vestergaard, Carsten Bøcker Pedersen, Jakob Christensen, Kreesten Meldgaard Madsen, Jørn Olsen, Preben Bo Mortense. Febrile seizures and risk of schizophrenia. Schizophrenia research. vol 73. issue 2-3. 2005-06-09. PMID:15653280. |
febrile seizure is a benign condition for most children, but experiments in animals and neuroimaging studies in humans suggest that some febrile seizures may damage the hippocampus, a brain area of possible importance in schizophrenia. |
2005-06-09 |
2023-08-12 |
Not clear |
| Gonzalo Flores, Adriana B Silva-Gómez, Osvaldo Ibáñez, Remi Quirion, Lalit K Srivastav. Comparative behavioral changes in postpubertal rats after neonatal excitotoxic lesions of the ventral hippocampus and the prefrontal cortex. Synapse (New York, N.Y.). vol 56. issue 3. 2005-06-07. PMID:15765522. |
the neonatal ventral hippocampal (nvh) and the neonatal prefrontal cortex (npfc) lesions in rats have been used as models to test the hypothesis that early neurodevelopmental abnormalities lead to behavioral changes putatively linked to schizophrenia. |
2005-06-07 |
2023-08-12 |
rat |
| P J Harrison, D R Weinberge. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Molecular psychiatry. vol 10. issue 1. 2005-06-02. PMID:15263907. |
the morphological correlates of schizophrenia are subtle, and range from a slight reduction in brain size to localized alterations in the morphology and molecular composition of specific neuronal, synaptic, and glial populations in the hippocampus, dorsolateral prefrontal cortex, and dorsal thalamus. |
2005-06-02 |
2023-08-12 |
Not clear |
| Masayuki Ito, Iris Depaz, Peter Wilce, Toshimitsu Suzuki, Shin-ichi Niwa, Izuru Matsumot. Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia. Neuroscience letters. vol 378. issue 3. 2005-06-02. PMID:15781144. |
because previous studies have supported abnormalities in neuronal cytoarchitecture and/or development in the schizophrenia brain, we examined the expression of hnp22 in the anterior cingulate cortex, the hippocampus and the prefrontal cortex of schizophrenic and normal control postmortem brains using high-sensitive immunohistochemistry. |
2005-06-02 |
2023-08-12 |
human |
| Sharon L Eastwood, Philip W J Burnet, Paul J Harriso. Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia. Biological psychiatry. vol 57. issue 7. 2005-05-20. PMID:15820226. |
decreased hippocampal expression of the susceptibility gene ppp3cc and other calcineurin subunits in schizophrenia. |
2005-05-20 |
2023-08-12 |
Not clear |
| Anthony P Weiss, Iain Dewitt, Donald Goff, Tali Ditman, Stephan Hecker. Anterior and posterior hippocampal volumes in schizophrenia. Schizophrenia research. vol 73. issue 1. 2005-05-10. PMID:15567082. |
anterior and posterior hippocampal volumes in schizophrenia. |
2005-05-10 |
2023-08-12 |
Not clear |
| Anthony P Weiss, Iain Dewitt, Donald Goff, Tali Ditman, Stephan Hecker. Anterior and posterior hippocampal volumes in schizophrenia. Schizophrenia research. vol 73. issue 1. 2005-05-10. PMID:15567082. |
while the evidence for hippocampal structural abnormalities in schizophrenia is now well accepted, whether there is differentially greater volume loss within specific subregions of the hippocampus remains a matter of some debate. |
2005-05-10 |
2023-08-12 |
Not clear |
| Jessie S Chambers, Deirdre Thomas, Linda Saland, Rachael L Neve, Nora I Perrone-Bizzozer. Growth-associated protein 43 (GAP-43) and synaptophysin alterations in the dentate gyrus of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 29. issue 2. 2005-05-09. PMID:15694236. |
given the relationship of gap-43 and synaptophysin with the development and plasticity of synaptic connections, the observed alterations in the hippocampus of patients with schizophrenia may be related to cognitive deficits associated with this illness. |
2005-05-09 |
2023-08-12 |
human |
| Lise Rioux, Steven Edward Arnol. The expression of retinoic acid receptor alpha is increased in the granule cells of the dentate gyrus in schizophrenia. Psychiatry research. vol 133. issue 1. 2005-05-09. PMID:15698673. |
understanding the basis for this and how it affects downstream molecular pathways associated with hippocampal plasticity may provide insight into the dysfunctional connectivity of schizophrenia. |
2005-05-09 |
2023-08-12 |
Not clear |
| Héctor Romo-Parra, Jorge Aceves, Rafael Gutiérre. Tonic modulation of inhibition by dopamine D4 receptors in the rat hippocampus. Hippocampus. vol 15. issue 2. 2005-04-28. PMID:15476261. |
the entorhinal cortex, which is the cortical area most consistently and severely affected in schizophrenia constitutes the main input to the hippocampus. |
2005-04-28 |
2023-08-12 |
rat |
| Vicente Molina, Javier Sanz, Fernando Sarramea, Carlos Benito, Tomás Palom. Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity. Journal of psychiatric research. vol 39. issue 2. 2005-04-26. PMID:15589559. |
reduced volume and activity of the prefrontal (pf) cortical gray matter (gm) and hippocampal hypermetabolism are repeated findings in schizophrenia. |
2005-04-26 |
2023-08-12 |
Not clear |