| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vicente Molina, Javier Sanz, Fernando Sarramea, Carlos Benito, Tomás Palom. Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity. Journal of psychiatric research. vol 39. issue 2. 2005-04-26. PMID:15589559. |
patients with schizophrenia had lower pf metabolic activation and greater hippocampal activity than controls. |
2005-04-26 |
2023-08-12 |
Not clear |
| Vicente Molina, Javier Sanz, Fernando Sarramea, Carlos Benito, Tomás Palom. Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity. Journal of psychiatric research. vol 39. issue 2. 2005-04-26. PMID:15589559. |
patients with schizophrenia presented an inverse and significant association between gm deficit and hippocampal activity that was not observed in controls or in patients without schizophrenia. |
2005-04-26 |
2023-08-12 |
Not clear |
| Veena Kumari, Mrigen Das, Sheilagh Hodgins, Elizabeth Zachariah, Ian Barkataki, Michael Howlett, Tonmoy Sharm. Association between violent behaviour and impaired prepulse inhibition of the startle response in antisocial personality disorder and schizophrenia. Behavioural brain research. vol 158. issue 1. 2005-04-25. PMID:15680203. |
the neural substrates of ppi, especially the hippocampus, amygdala, thalamus and basal ganglia, are implicated in violence as well as in apd and schizophrenia. |
2005-04-25 |
2023-08-12 |
human |
| Atsushi Hashimoto, Sachie Chiba, Yukie Chib. Effect of systemic administration of D-serine on the levels of D- and L-serine in several brain areas and periphery of rat. European journal of pharmacology. vol 495. issue 2-3. 2005-04-20. PMID:15249164. |
because a structural abnormality and n-methyl-d-aspartate (nmda) receptor hypofunction has been demonstrated in the cortex and hippocampus of schizophrenic subjects, d-serine treatment may offer a new therapeutic approach to diseases related to the hypofunction of nmda receptors such as schizophrenia. |
2005-04-20 |
2023-08-12 |
human |
| Philip Seeman, David Weinshenker, Remi Quirion, Lalit K Srivastava, Sanjeev K Bhardwaj, David K Grandy, Richard T Premont, Tatyana D Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F O'dowd, Susan R George, Melissa L Perreault, Pekka T Männistö, Siobhan Robinson, Richard D Palmiter, Teresa Talleric. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 9. 2005-04-13. PMID:15716360. |
dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of dbh (dopamine beta-hydroxylase), drd4 receptors, gprk6 (g protein-coupled receptor kinase 6), comt (catechol-o-methyltransferase), or th-/-, dbhth/+ (tyrosine hydroxylase), and in rats born by cesarean-section. |
2005-04-13 |
2023-08-12 |
rat |
| Tsuyoshi Miyaoka, Rei Yasukawa, Shoichi Mizuno, Tsuruhei Sukegawa, Takuji Inagaki, Jun Horiguchi, Haruo Seno, Kazushige Oda, Hajime Kitagak. Proton magnetic resonance spectroscopy (1H-MRS) of hippocampus, basal ganglia, and vermis of cerebellum in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome). Journal of psychiatric research. vol 39. issue 1. 2005-04-12. PMID:15504421. |
proton magnetic resonance spectroscopy (1h-mrs) of hippocampus, basal ganglia, and vermis of cerebellum in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (gilbert's syndrome). |
2005-04-12 |
2023-08-12 |
Not clear |
| Miranda H Chakos, Scott A Schobel, Hongbin Gu, Guido Gerig, Daniel Bradford, Cecil Charles, Jeffrey A Lieberma. Duration of illness and treatment effects on hippocampal volume in male patients with schizophrenia. The British journal of psychiatry : the journal of mental science. vol 186. 2005-04-11. PMID:15630120. |
duration of illness and treatment effects on hippocampal volume in male patients with schizophrenia. |
2005-04-11 |
2023-08-12 |
Not clear |
| Miranda H Chakos, Scott A Schobel, Hongbin Gu, Guido Gerig, Daniel Bradford, Cecil Charles, Jeffrey A Lieberma. Duration of illness and treatment effects on hippocampal volume in male patients with schizophrenia. The British journal of psychiatry : the journal of mental science. vol 186. 2005-04-11. PMID:15630120. |
reduced hippocampal volume is a consistently described structural abnormality in schizophrenia but its cause and timing are not known. |
2005-04-11 |
2023-08-12 |
Not clear |
| G Benitez-King, G Ramírez-Rodríguez, L Ortíz, I Mez. The neuronal cytoskeleton as a potential therapeutical target in neurodegenerative diseases and schizophrenia. Current drug targets. CNS and neurological disorders. vol 3. issue 6. 2005-03-23. PMID:15581421. |
increase in non-phosphorylated map2 and map1b at hippocampus has been suggested as responsible for somatodendritic and cytoarchitectural abnormalities found in schizophrenia. |
2005-03-23 |
2023-08-12 |
Not clear |
| Ken Sawada, Alasdair M Barr, Masato Nakamura, Kunimasa Arima, Clint E Young, Andrew J Dwork, Peter Falkai, Anthony G Phillips, William G Hone. Hippocampal complexin proteins and cognitive dysfunction in schizophrenia. Archives of general psychiatry. vol 62. issue 3. 2005-03-21. PMID:15753239. |
hippocampal complexin proteins and cognitive dysfunction in schizophrenia. |
2005-03-21 |
2023-08-12 |
Not clear |
| Lynne E Rueter, Michael E Ballard, Kelly B Gallagher, Ana Maria Basso, Peter Curzon, Kathy L Kohlhaa. Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia. Psychopharmacology. vol 176. issue 3-4. 2005-03-01. PMID:15179541. |
chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia. |
2005-03-01 |
2023-08-12 |
rat |
| Elizabeth Scarr, Geoffrey Pavey, David Copolov, Brian Dea. Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474910. |
there is strong evidence that hippocampal 5-hydroxytryptamine (5-ht) systems are affected in schizophrenia and hence we have studied a number of markers of the 5-ht system in hippocampi from subjects with schizophrenia. |
2005-03-01 |
2023-08-12 |
human |
| Elizabeth Scarr, Geoffrey Pavey, David Copolov, Brian Dea. Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474910. |
there were significant decreases in the density of [(3)h]ketanserin binding to the 5-ht(2a) receptor (5-ht(2a)r) in the cornu ammonis (ca) 3 (p=0.006), ca 1 (stratum radiatum p=0.02; pyramidal layer p=0.0008) and subiculum (pyramidal layer p=0.0004), as well as methiothepin-insensitive [(3)h]sumatriptan binding to the 5-ht(1f)r in the ca 1 (p=0.016), stratum radiatum/lacunosum moleculare (p=0.04) and subiculum (p=0.015) from subjects with schizophrenia. |
2005-03-01 |
2023-08-12 |
human |
| Robin M Murray, Pak Sham, Jim Van Os, Jolanta Zanelli, Mary Cannon, Colm McDonal. A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophrenia research. vol 71. issue 2-3. 2005-03-01. PMID:15474912. |
perinatal complications such as hypoxia are known to result in smaller volume of the amygdala and hippocampus, which have been frequently reported to be reduced in schizophrenia; familial predisposition to schizophrenia is also associated with decreased volume of these structures. |
2005-03-01 |
2023-08-12 |
human |
| John G Howland, Darren K Hannesson, Anthony G Phillip. Delayed onset of prepulse inhibition deficits following kainic acid treatment on postnatal day 7 in rats. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548207. |
permanent or temporary lesions of limbic structures such as the ventral hippocampus and basolateral amygdala in rats on postnatal day (pnd) 7 result in functional changes similar to some behavioural and cognitive signs of schizophrenia. |
2005-03-01 |
2023-08-12 |
rat |
| S E J Connor, V Ng, C McDonald, K Schulze, K Morgan, P Dazzan, R M Murra. A study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder. Neuroradiology. vol 46. issue 7. 2005-02-25. PMID:15205862. |
a study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder. |
2005-02-25 |
2023-08-12 |
human |
| S E J Connor, V Ng, C McDonald, K Schulze, K Morgan, P Dazzan, R M Murra. A study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder. Neuroradiology. vol 46. issue 7. 2005-02-25. PMID:15205862. |
subtle structural hippocampal abnormalities have been demonstrated in patients with schizophrenia. |
2005-02-25 |
2023-08-12 |
human |
| F M Benes, R E Burke, J Walsh, S Berretta, D Matzilevich, M Minns, C Konrad. Acute amygdalar activation induces an upregulation of multiple monoamine G protein coupled pathways in rat hippocampus. Molecular psychiatry. vol 9. issue 10. 2005-02-15. PMID:15170462. |
a "partial" rodent model for schizophrenia has been used to characterize the regulation of hippocampal genes in response to amygdalar activation. |
2005-02-15 |
2023-08-12 |
rat |
| Peter Flagstad, Birte Y Glenthøj, Michael Didrikse. Cognitive deficits caused by late gestational disruption of neurogenesis in rats: a preclinical model of schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 2. 2005-02-15. PMID:15578007. |
furthermore, it has been shown that the morphological changes produced by the perturbation are relevant to schizophrenia with reduced thickness of the hippocampus, thalamus, and cortical regions. |
2005-02-15 |
2023-08-12 |
rat |
| Snezana Kusljic, Maarten van den Buus. Functional dissociation between serotonergic pathways in dorsal and ventral hippocampus in psychotomimetic drug-induced locomotor hyperactivity and prepulse inhibition in rats. The European journal of neuroscience. vol 20. issue 12. 2005-02-15. PMID:15610175. |
altered hippocampal function and brain serotonin activity are implicated in the development and symptoms of schizophrenia. |
2005-02-15 |
2023-08-12 |
rat |