| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eva M Meisenzahl, Doerthe Seifert, Ronald Bottlender, Stefan Teipel, Thomas Zetzsche, Markus Jäger, Nikolaos Koutsouleris, Gisela Schmitt, Johanna Scheuerecker, Bernhard Burgermeister, Harald Hampel, Tobias Rupprecht, Christine Born, Maximilian Reiser, Hans-Jürgen Möller, Thomas Frod. Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. European archives of psychiatry and clinical neuroscience. vol 260. issue 2. 2010-05-26. PMID:19488671. |
differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. |
2010-05-26 |
2023-08-12 |
human |
| Eva M Meisenzahl, Doerthe Seifert, Ronald Bottlender, Stefan Teipel, Thomas Zetzsche, Markus Jäger, Nikolaos Koutsouleris, Gisela Schmitt, Johanna Scheuerecker, Bernhard Burgermeister, Harald Hampel, Tobias Rupprecht, Christine Born, Maximilian Reiser, Hans-Jürgen Möller, Thomas Frod. Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. European archives of psychiatry and clinical neuroscience. vol 260. issue 2. 2010-05-26. PMID:19488671. |
several studies have demonstrated that structural brain change is detectable in the hippocampus in both patients, with schizophrenia and major depression. |
2010-05-26 |
2023-08-12 |
human |
| Eva M Meisenzahl, Doerthe Seifert, Ronald Bottlender, Stefan Teipel, Thomas Zetzsche, Markus Jäger, Nikolaos Koutsouleris, Gisela Schmitt, Johanna Scheuerecker, Bernhard Burgermeister, Harald Hampel, Tobias Rupprecht, Christine Born, Maximilian Reiser, Hans-Jürgen Möller, Thomas Frod. Differences in hippocampal volume between major depression and schizophrenia: a comparative neuroimaging study. European archives of psychiatry and clinical neuroscience. vol 260. issue 2. 2010-05-26. PMID:19488671. |
the objectives of this study are to investigate whether hippocampal volumes are reduced in patients with schizophrenia and those with major depression with the same duration of illness compared to healthy controls and to assess further changes at different disease stages. |
2010-05-26 |
2023-08-12 |
human |
| Robert Freedman, Dan Goldowit. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Progress in neurobiology. vol 90. issue 2. 2010-05-26. PMID:19853005. |
the story told in this chapter is about the use of the in oculo transplant method to illuminate intrinsic and extrinsic features that underlie the development of the dentate gyrus and adjacent hippocampus and the role of one molecule in the hippocampus and schizophrenia. |
2010-05-26 |
2023-08-12 |
human |
| Robert Freedman, Dan Goldowit. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Progress in neurobiology. vol 90. issue 2. 2010-05-26. PMID:19853005. |
evidence for the role of the alpha 7-nicotinic acetylcholine receptor in the development and function of these neurons in rodents has led to human trials of nicotinic agonists for cognitive dysfunction in schizophrenia and the possibility of improving hippocampal development in children at risk for schizophrenia by perinatal supplementation with choline, which can act as an alpha 7-nicotinic acetylcholine receptor agonist. |
2010-05-26 |
2023-08-12 |
human |
| Gaga Kochlamazashvili, Oleg Senkov, Sergei Grebenyuk, Catrina Robinson, Mei-Fang Xiao, Katharina Stummeyer, Rita Gerardy-Schahn, Andreas K Engel, Larry Feig, Alexey Semyanov, Vishnu Suppiramaniam, Melitta Schachner, Alexander Dityate. Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 11. 2010-05-18. PMID:20237287. |
abnormalities in psa and ncam expression are associated with schizophrenia in humans and cause deficits in hippocampal synaptic plasticity and contextual fear conditioning in mice. |
2010-05-18 |
2023-08-12 |
mouse |
| Simone Boer, Diego Sanchez, Ivo Reinieren, Tom van den Boom, Madhara Udawela, Elizabeth Scarr, Maria D Ganfornina, Brian Dea. Decreased kainate receptors in the hippocampus of apolipoprotein D knockout mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 2. 2010-05-13. PMID:19963028. |
there is also a large body of evidence that cortical and hippocampal glutamatergic, serotonergic and cholinergic systems are affected by the pathophysiology of schizophrenia. |
2010-05-13 |
2023-08-12 |
mouse |
| E S Lutkenhoff, T G van Erp, M A Thomas, S Therman, M Manninen, M O Huttunen, J Kaprio, J Lönnqvist, J O'Neill, T D Canno. Proton MRS in twin pairs discordant for schizophrenia. Molecular psychiatry. vol 15. issue 3. 2010-05-11. PMID:18645571. |
we acquired magnetic resonance spectra (tr/te=3000/30 ms) at voxels in the mesial prefrontal gray matter, left prefrontal white matter and left hippocampus in 14 twin pairs discordant for schizophrenia (2 monozygotic, 12 dizygotic), 13 healthy twin pairs (4 monozygotic, 9 dizygotic) and 1 additional unaffected co-twin of a schizophrenia proband. |
2010-05-11 |
2023-08-12 |
human |
| E S Lutkenhoff, T G van Erp, M A Thomas, S Therman, M Manninen, M O Huttunen, J Kaprio, J Lönnqvist, J O'Neill, T D Canno. Proton MRS in twin pairs discordant for schizophrenia. Molecular psychiatry. vol 15. issue 3. 2010-05-11. PMID:18645571. |
in the left hippocampus voxel, levels of naa (23%), cr (22%) and cho (36%) were higher in schizophrenia patients compared with controls. |
2010-05-11 |
2023-08-12 |
human |
| E S Lutkenhoff, T G van Erp, M A Thomas, S Therman, M Manninen, M O Huttunen, J Kaprio, J Lönnqvist, J O'Neill, T D Canno. Proton MRS in twin pairs discordant for schizophrenia. Molecular psychiatry. vol 15. issue 3. 2010-05-11. PMID:18645571. |
thus, reduced mesial prefrontal cortical glu and elevated hippocampal naa, cr and cho may represent trait markers of schizophrenia risk and, when exacerbated, state markers of schizophrenia itself. |
2010-05-11 |
2023-08-12 |
human |
| Hui-min Chang, Song-tao Qi, Kai-jun Yang, Ke-wan Wang, Zhi-wan Guo, Hao Wan. [Proton magnetic resonance spectroscopic imaging of the hippocampus in schizophrenia patients before and after surgery]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 29. issue 5. 2010-05-04. PMID:19460730. |
[proton magnetic resonance spectroscopic imaging of the hippocampus in schizophrenia patients before and after surgery]. |
2010-05-04 |
2023-08-12 |
Not clear |
| Hui-min Chang, Song-tao Qi, Kai-jun Yang, Ke-wan Wang, Zhi-wan Guo, Hao Wan. [Proton magnetic resonance spectroscopic imaging of the hippocampus in schizophrenia patients before and after surgery]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 29. issue 5. 2010-05-04. PMID:19460730. |
to explore the features of proton magnetic resonance spectroscopy (1h-mrs) of the hippocampus in schizophrenia patients before and after stereotactic neurosurgery. |
2010-05-04 |
2023-08-12 |
Not clear |
| Jason R Tregellas, Ann Olincy, Lynn Johnson, Jody Tanabe, Shireen Shatti, Laura F Martin, Debra Singel, Yiping P Du, Ferenc Soti, William R Kem, Robert Freedma. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:19956085. |
increased hemodynamic activity in the hippocampus in schizophrenia is found during many tasks, including smooth pursuit eye movements, and may reflect inhibitory dysfunction. |
2010-04-28 |
2023-08-12 |
human |
| Jason R Tregellas, Ann Olincy, Lynn Johnson, Jody Tanabe, Shireen Shatti, Laura F Martin, Debra Singel, Yiping P Du, Ferenc Soti, William R Kem, Robert Freedma. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 4. 2010-04-28. PMID:19956085. |
the findings are consistent with the previously established function of alpha7-nicotinic receptors on inhibitory interneurons in the hippocampus and with genetic evidence for deficits in these receptors in schizophrenia. |
2010-04-28 |
2023-08-12 |
human |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. |
2010-04-26 |
2023-08-12 |
Not clear |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
hippocampal volume decrement may be one of the changes that most closely pre-date schizophrenia onset. |
2010-04-26 |
2023-08-12 |
Not clear |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
studying hippocampal developmental morphology in adolescent or young adult biological relatives of schizophrenia probands has the potential to further our understanding of the neurodevelopmental etiology of schizophrenia and to discover biomarkers that may aid its early identification. |
2010-04-26 |
2023-08-12 |
Not clear |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
similar to schizophrenia probands, unaffected biological relatives of probands had significantly smaller hippocampus volumes than controls; which correspond to inward displacements in shape deformities principally in the anterior hippocampal subregions. |
2010-04-26 |
2023-08-12 |
Not clear |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
similar hippocampal volume deficits-obstetric complications relationships were observed among schizophrenia probands. |
2010-04-26 |
2023-08-12 |
Not clear |
| Beng-Choon Ho, Vincent Magnott. Hippocampal volume deficits and shape deformities in young biological relatives of schizophrenia probands. NeuroImage. vol 49. issue 4. 2010-04-26. PMID:19941961. |
hippocampal abnormalities in schizophrenia are likely to be mediated by different neurobiological mechanisms, including factors associated with obstetric complications which occur during early neurodevelopment. |
2010-04-26 |
2023-08-12 |
Not clear |