All Relations between Schizophrenia and hippocampus

Publication Sentence Publish Date Extraction Date Species
Shani Stern, Lei Zhang, Meiyan Wang, Rebecca Wright, Idan Rosh, Yara Hussein, Tchelet Stern, Ashwani Choudhary, Utkarsh Tripathi, Patrick Reed, Hagit Sadis, Ritu Nayak, Aviram Shemen, Karishma Agarwal, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P D Mendes, Tithi D Baul, Julien G Roth, Shashank Coorapati, Marco P Boks, W Richard McCombie, Hilleke Hulshoff Pol, Kristen J Brennand, János M Réthelyi, René S Kahn, Maria C Marchetto, Fred H Gag. Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission. Molecular psychiatry. 2024-05-04. PMID:38704507. our measurements that were obtained from schizophrenia patients and their monozygotic twin and compared also to control healthy twins point to hippocampal synaptic deficits as a central mechanism in schizophrenia. 2024-05-04 2024-05-07 Not clear
Xueru Wang, Zijie Li, Shihui Kuai, Xuejiao Wang, Jingyu Chen, Yanping Yang, Ling Qi. Correlation between desynchrony of hippocampal neural activity and hyperlocomotion in the model mice of schizophrenia and therapeutic effects of aripiprazole. CNS neuroscience & therapeutics. vol 30. issue 5. 2024-05-04. PMID:38702935. correlation between desynchrony of hippocampal neural activity and hyperlocomotion in the model mice of schizophrenia and therapeutic effects of aripiprazole. 2024-05-04 2024-05-06 mouse
Xueru Wang, Zijie Li, Shihui Kuai, Xuejiao Wang, Jingyu Chen, Yanping Yang, Ling Qi. Correlation between desynchrony of hippocampal neural activity and hyperlocomotion in the model mice of schizophrenia and therapeutic effects of aripiprazole. CNS neuroscience & therapeutics. vol 30. issue 5. 2024-05-04. PMID:38702935. the hippocampus has been reported to be morphologically and neurochemically altered in schizophrenia (sz). 2024-05-04 2024-05-06 mouse
Ying-Jay Liou, Mu-N Liu, Kai-Chun Yang, Li-Yu Hu, Wen-Chi Hsieh, Yuan-Hwa Cho. Hippocampal subfields in remitted schizophrenia. Journal of the Chinese Medical Association : JCMA. 2024-04-24. PMID:38656303. hippocampal subfields in remitted schizophrenia. 2024-04-24 2024-04-28 Not clear
Ying-Jay Liou, Mu-N Liu, Kai-Chun Yang, Li-Yu Hu, Wen-Chi Hsieh, Yuan-Hwa Cho. Hippocampal subfields in remitted schizophrenia. Journal of the Chinese Medical Association : JCMA. 2024-04-24. PMID:38656303. current evidence of volume changes in hippocampal subdivisions in schizophrenia remains inconsistent, and few studies have investigated the relationship between regional hippocampal volumes and symptom remission. 2024-04-24 2024-04-28 Not clear
Abdalla M Albeely, Olivia O F Williams, Colin R Blight, Rachel-Karson Thériault, Melissa L Perreaul. Sex differences in neuronal oscillatory activity and memory in the methylazoxymethanol acetate model of schizophrenia. Schizophrenia research. vol 267. 2024-04-21. PMID:38643726. the purpose of this study was to determine whether differences exist between male and female mam rats in neuronal oscillatory function within and between the prefrontal cortex (pfc), ventral hippocampus (vhip) and thalamus, behaviour, and in proteins linked to schizophrenia neuropathology. 2024-04-21 2024-04-24 rat
Shane Crinion, Cathy A Wyse, Gary Donohoe, Lorna M Lopez, Derek W Morri. Mendelian randomization analysis using GWAS and eQTL data to investigate the relationship between chronotype and neuropsychiatric disorders and their molecular basis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2024-03-29. PMID:38549512. we identified 12 eqtls where gene expression changes in brain or blood were causal for one of the phenotypes, including two eqtls for snx19 in hippocampus and hypothalamus that were causal for schizophrenia. 2024-03-29 2024-03-31 Not clear
Laura López-Molina, Anna Sancho-Balsells, Omar Al-Massadi, Enrica Montalban, Jordi Alberch, Belén Arranz, Jean-Antoine Girault, Albert Giral. Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia. Neurobiology of disease. 2024-03-29. PMID:38552722. hippocampal pyk2 regulates specific social skills: implications for schizophrenia. 2024-03-29 2024-04-01 mouse
Laura López-Molina, Anna Sancho-Balsells, Omar Al-Massadi, Enrica Montalban, Jordi Alberch, Belén Arranz, Jean-Antoine Girault, Albert Giral. Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia. Neurobiology of disease. 2024-03-29. PMID:38552722. in summary, our results indicate that pyk2 might play a role in regulating specific social skills likely via mitochondrial dynamics and that there might be a link between pyk2 levels in hippocampal neurons and social disturbances in schizophrenia. 2024-03-29 2024-04-01 mouse
Hannah B Elam, Stephanie M Perez, Jennifer J Donegan, Nicole E Eassa, Daniel J Lodg. Knockdown of Lhx6 during embryonic development results in neurophysiological alterations and behavioral deficits analogous to schizophrenia in adult rats. Schizophrenia research. vol 267. 2024-03-26. PMID:38531158. a decreased expression of specific interneuron subtypes, containing either the calcium binding protein parvalbumin (pv) or the neurotransmitter somatostatin (sst), are observed in the cortex and hippocampus of both patients with schizophrenia and rodent models used to study the disorder. 2024-03-26 2024-03-29 human
Thamyris Santos-Silva, Caio Fábio Baeta Lopes, Doğukan Hazar Ülgen, Danielle A Guimarães, Francisco S Guimarães, Luciane Carla Alberici, Carmen Sandi, Felipe V Gome. Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia. Schizophrenia bulletin. 2024-03-25. PMID:38525594. adolescent stress-induced ventral hippocampus redox dysregulation underlies behavioral deficits and excitatory/inhibitory imbalance related to schizophrenia. 2024-03-25 2024-03-27 Not clear
Elias A Samona, Asadur Chowdury, John Kopchick, Patricia Thomas, Usha Rajan, Dalal Khatib, Caroline Zajac-Benitez, Alireza Amirsadri, Luay Haddad, Jeffrey A Stanley, Vaibhav A Diwadka. The importance of covert memory consolidation in schizophrenia: Dysfunctional network profiles of the hippocampus and the dorsolateral prefrontal cortex. Psychiatry research. Neuroimaging. vol 340. 2024-03-06. PMID:38447230. the importance of covert memory consolidation in schizophrenia: dysfunctional network profiles of the hippocampus and the dorsolateral prefrontal cortex. 2024-03-06 2024-03-09 Not clear
Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling-Leffle. Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences. 2024-02-27. PMID:38410450. extrapolation of cell-type results to brain regions reveals important patterns for schizophrenia with distinct subregions in the hippocampus and amygdala exhibiting the highest significance. 2024-02-27 2024-03-02 mouse
Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling-Leffle. Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences. 2024-02-27. PMID:38410450. using functional mri connectivity from cases with schizophrenia and neurotypical controls, we identified brain networks that distinguished cases from controls that also confirmed involvement of the central and lateral amygdala, hippocampal body, and prefrontal cortex. 2024-02-27 2024-03-02 mouse
Mariélia B L de Freitas, Licia P Luna, Márcia Beatriz, Romulo Kunrath Pinto, Candida H Lopes Alves, Lays Bittencourt, Antônio E Nardi, Viola Oertel, André B Veras, David Freitas de Lucena, Gilberto Sousa Alve. Resting-state fMRI is associated with trauma experiences, mood and psychosis in Afro-descendants with bipolar disorder and schizophrenia. Psychiatry research. Neuroimaging. vol 340. 2024-02-26. PMID:38408419. bipolar disorder (bd) and schizophrenia (scz) may exhibit functional abnormalities in several brain areas, including the medial temporal and prefrontal cortex and hippocampus; however, a less explored topic is how brain connectivity is linked to premorbid trauma experiences and clinical features in non-caucasian samples of scz and bd. 2024-02-26 2024-03-02 Not clear
Cristina Lorca, María Fernández-Rhodes, Jose Antonio Sánchez Milán, María Mulet, Félix Elortza, Alfredo Ramos-Miguel, Luis F Callado, J Javier Meana, Maria Mur, Iolanda Batalla, Elisabet Vilella, Aida Serra, Xavier Gallart-Pala. Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255234. here, by using next-generation discovery-driven proteomics, we investigate the potential role(s) of brain evs (bevs) in schizophrenia (sz) by analyzing these vesicles from the three post-mortem anatomical brain regions: the prefrontal cortex (pfc), hippocampus (hc), and caudate (cau). 2024-01-23 2024-01-25 human
Natalie L Wellard, Nicholas E Clifton, Elliott Rees, Kerrie L Thomas, Jeremy Hal. The Association of Hippocampal Long-Term Potentiation-Induced Gene Expression with Genetic Risk for Psychosis. International journal of molecular sciences. vol 25. issue 2. 2024-01-23. PMID:38256020. genomic studies focusing on the contribution of common and rare genetic variants of schizophrenia and bipolar disorder support the view that substantial risk is conferred through molecular pathways involved in synaptic plasticity in the neurons of cortical and subcortical brain regions, including the hippocampus. 2024-01-23 2024-01-25 Not clear
Daphne Nakhid, Darpal Patel, Carly A McMorris, W Ben Gibbard, Christina Tortorelli, Jacqueline Pei, Catherine Lebe. Limbic brain subregions associated with mental health symptoms in youth with and without prenatal alcohol exposure. Alcohol, clinical & experimental research. vol 47. issue 11. 2024-01-16. PMID:38226747. limbic brain structures such as the hippocampus, thalamus, and amygdala often exhibit smaller volumes in youth with pae, and similar volume reductions are observed in unexposed youth with symptoms of depression, bipolar disorder, anxiety, and schizophrenia. 2024-01-16 2024-01-18 Not clear
Xiaoe Lang, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao, Xiangyang Zhan. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 19. issue 1. 2024-01-04. PMID:38176805. association between hippocampal subfields and clinical symptoms of first-episode and drug naive schizophrenia patients during 12 weeks of risperidone treatment. 2024-01-04 2024-01-07 human
Xiaoe Lang, Dongmei Wang, Dachun Chen, Meihong Xiu, Huixia Zhou, Li Wang, Bo Cao, Xiangyang Zhan. Association Between Hippocampal Subfields and Clinical Symptoms of First-Episode and Drug Naive Schizophrenia Patients During 12 Weeks of Risperidone Treatment. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 19. issue 1. 2024-01-04. PMID:38176805. small hippocampal size may be implicated in the pathogenesis and psychopathology of schizophrenia (scz). 2024-01-04 2024-01-07 human