| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carlos Jimenez Naranjo, Ashleigh L Osborne, Katrina Weston-Gree. Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31108177. |
effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly i:c rat model of schizophrenia. |
2020-03-30 |
2023-08-13 |
rat |
| David J Titus, Timothy Johnstone, Nathan H Johnson, Sidney H London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W Gee, Coleen M Atkin. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. PloS one. vol 14. issue 10. 2020-03-11. PMID:31581202. |
the α7 nicotinic acetylcholine receptor (nachr) is highly expressed in the hippocampus and reduced expression and function of this receptor are linked with cognitive impairments in alzheimer's disease and schizophrenia. |
2020-03-11 |
2023-08-13 |
human |
| Venkataram Shivakumar, Vanteemar S Sreeraj, Manjula Subbanna, Sunil V Kalmady, Anekal C Amaresha, Janardhanan C Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramania. Differential impact of interleukin-6 promoter gene polymorphism on hippocampal volume in antipsychotic-naïve schizophrenia patients. Indian journal of psychiatry. vol 62. issue 1. 2020-02-11. PMID:32001929. |
differential impact of interleukin-6 promoter gene polymorphism on hippocampal volume in antipsychotic-naïve schizophrenia patients. |
2020-02-11 |
2023-08-13 |
Not clear |
| Venkataram Shivakumar, Vanteemar S Sreeraj, Manjula Subbanna, Sunil V Kalmady, Anekal C Amaresha, Janardhanan C Narayanaswamy, Monojit Debnath, Ganesan Venkatasubramania. Differential impact of interleukin-6 promoter gene polymorphism on hippocampal volume in antipsychotic-naïve schizophrenia patients. Indian journal of psychiatry. vol 62. issue 1. 2020-02-11. PMID:32001929. |
single-nucleotide polymorphism (snp) (rs18000795) within the promoter region of interleukin-6 (il-6) gene was earlier noted to have a differential susceptibility on hippocampal volume in schizophrenia (scz). |
2020-02-11 |
2023-08-13 |
Not clear |
| Xu Li, Zheng-Hui Yi, Qin-Yu Lv, Min-Yi Chu, Hui-Xin Hu, Jin-Hong Wang, Jian-Ye Zhang, Eric E F Cheung, Raymond C K Cha. Clinical utility of the dual n-back task in schizophrenia: A functional imaging approach. Psychiatry research. Neuroimaging. vol 284. 2020-02-06. PMID:30658243. |
the right hippocampus was less deactivated in schizophrenia patients compared with healthy controls. |
2020-02-06 |
2023-08-13 |
human |
| Thomas A Lanz, Veronica Reinhart, Mark J Sheehan, Stacey J Sukoff Rizzo, Susan E Bove, Larry C James, Dmitri Volfson, David A Lewis, Robin J Kleima. Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder. Translational psychiatry. vol 9. issue 1. 2020-02-06. PMID:31123247. |
postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder. |
2020-02-06 |
2023-08-13 |
human |
| H Trantham-Davidson, A Lavi. Loss of dysbindin-1 affects GABAergic transmission in the PFC. Psychopharmacology. vol 236. issue 11. 2020-01-28. PMID:31201475. |
it has been shown that dystrobrevin-binding protein 1 gene that encodes the protein dysbindin-1 is associated with risk for cognitive deficits, and studies have shown decreases in glutamate and correlated decreases in dysbindin-1 protein in the prefrontal cortex (pfc) and hippocampus of post-mortem tissue from schizophrenia patients. |
2020-01-28 |
2023-08-13 |
mouse |
| Yifan Zhang, Xiaohong Gong, Zhiyang Yin, Lingling Cui, Jian Yang, Pengshuo Wang, Yifang Zhou, Xiaowei Jiang, Shengnan Wei, Fei Wang, Yanqing Tan. Association between NRGN gene polymorphism and resting-state hippocampal functional connectivity in schizophrenia. BMC psychiatry. vol 19. issue 1. 2020-01-21. PMID:30953482. |
association between nrgn gene polymorphism and resting-state hippocampal functional connectivity in schizophrenia. |
2020-01-21 |
2023-08-13 |
Not clear |
| Isabel Maurus, Alkomiet Hasan, Astrid Röh, Shun Takahashi, Boris Rauchmann, Daniel Keeser, Berend Malchow, Andrea Schmitt, Peter Falka. Neurobiological effects of aerobic exercise, with a focus on patients with schizophrenia. European archives of psychiatry and clinical neuroscience. vol 269. issue 5. 2020-01-09. PMID:31115660. |
structural magnetic resonance imaging studies showed a volume increase in the hippocampus and cortical regions in schizophrenia patients and healthy controls after endurance training. |
2020-01-09 |
2023-08-13 |
Not clear |
| Wei-Lieh Huang, Chao-Yu Liu, Hon-Man Liu, Chih-Min Liu, Ming H Hsie. Sex as a Moderating Factor in the Relationship Between Hippocampal Volume and Sensory Gating in Patients With Schizophrenia. Clinical EEG and neuroscience. vol 50. issue 4. 2019-12-20. PMID:30862179. |
sex as a moderating factor in the relationship between hippocampal volume and sensory gating in patients with schizophrenia. |
2019-12-20 |
2023-08-13 |
Not clear |
| Wei-Lieh Huang, Chao-Yu Liu, Hon-Man Liu, Chih-Min Liu, Ming H Hsie. Sex as a Moderating Factor in the Relationship Between Hippocampal Volume and Sensory Gating in Patients With Schizophrenia. Clinical EEG and neuroscience. vol 50. issue 4. 2019-12-20. PMID:30862179. |
building on the knowledge of sex differences in auditory sensory gating in schizophrenia and hippocampal involvement in sensory gating, this study aimed to investigate sex as a potential moderator of the association between hippocampal volume and p50 in schizophrenia. |
2019-12-20 |
2023-08-13 |
Not clear |
| Wei-Lieh Huang, Chao-Yu Liu, Hon-Man Liu, Chih-Min Liu, Ming H Hsie. Sex as a Moderating Factor in the Relationship Between Hippocampal Volume and Sensory Gating in Patients With Schizophrenia. Clinical EEG and neuroscience. vol 50. issue 4. 2019-12-20. PMID:30862179. |
auditory p50 gating and hippocampal volume were measured in 16 male and 15 female patients with schizophrenia. |
2019-12-20 |
2023-08-13 |
Not clear |
| Charles Schleifer, Amy Lin, Leila Kushan, Jie Lisa Ji, Genevieve Yang, Carrie E Bearden, Alan Anticevi. Dissociable Disruptions in Thalamic and Hippocampal Resting-State Functional Connectivity in Youth with 22q11.2 Deletions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 7. 2019-12-11. PMID:30478034. |
resting-state functional connectivity mri studies in idiopathic schizophrenia have consistently revealed disruption of thalamic and hippocampal circuitry. |
2019-12-11 |
2023-08-13 |
human |
| Emanuele Felice Osimo, Katherine Beck, Tiago Reis Marques, Oliver D Howe. Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures. Molecular psychiatry. vol 24. issue 4. 2019-12-03. PMID:29511299. |
among the results, we found a significant reduction in synaptophysin in schizophrenia in the hippocampus (effect size: -0.65, p < 0.01), frontal (effect size: -0.36, p = 0.04), and cingulate cortices (effect size: -0.54, p = 0.02), but no significant changes for synaptophysin in occipital and temporal cortices, and no changes for snap-25, psd-95, vamp, and syntaxin in frontal cortex. |
2019-12-03 |
2023-08-13 |
Not clear |
| Emanuele Felice Osimo, Katherine Beck, Tiago Reis Marques, Oliver D Howe. Synaptic loss in schizophrenia: a meta-analysis and systematic review of synaptic protein and mRNA measures. Molecular psychiatry. vol 24. issue 4. 2019-12-03. PMID:29511299. |
our findings of moderate-large reductions in synaptophysin in hippocampus and frontal cortical regions, and a tendency for reductions in other pre- and postsynaptic proteins in the hippocampus are consistent with models that implicate synaptic loss in schizophrenia. |
2019-12-03 |
2023-08-13 |
Not clear |
| Tomás Palomo, Richard M. Kostrzewa, Trevor Archer, Richard J. Beninge. Neurodevelopmental liabilities in schizophrenia and affective disorders. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754154. |
animal studies have found that rats that undergo exocitotoxic damage to the ventral hippocampus on postnatal day 7 develop exaggerated sensitivity to dopamine-stimulating drugs or to stressful stimuli that becomes apparent after sexual maturity but not before, providing a neurodevelopmental model of schizophrenia. |
2019-11-20 |
2023-08-12 |
rat |
| Jenny Walker, Vivienne Curtis, Philip Shaw, Robin M. Murra. Schizophrenia and bipolar disorder are distinguished mainly by differences in neurodevelopment. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754157. |
structural abnormalities of the brain have been identified in both schizophrenia and bipolar disorder, but while the volume of the amygdala and hippocampus appears decreased in schizophrenia, this is not the case in bipolar disorder; indeed there are some suggestions of increased volume of the amygdala. |
2019-11-20 |
2023-08-12 |
human |
| Barbara K. Lipska, Daniel R. Weinberge. A neurodevelopmental model of schizophrenia: neonatal disconnection of the hippocampus. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754160. |
a neurodevelopmental model of schizophrenia: neonatal disconnection of the hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| R. J. Beninger, A. Jhamandas, H. Aujla, L. Xue, R. V. Dagnone, R. J. Boegman, K. Jhamanda. Neonatal exposure to the glutamate receptor antagonist MK-801: effects on locomotor activity and pre-pulse inhibition before and after sexual maturity in rats. Neurotoxicity research. vol 4. issue 5-6. 2019-11-20. PMID:12754161. |
neonatal lesions of the ventral hippocampus in rats lead to post- but not pre-pubertal behavioral changes suggesting adolescent onset of dopaminergic hypersensitivity and providing an animal model of schizophrenia. |
2019-11-20 |
2023-08-12 |
rat |
| Aparna Rajagopalan, Nadine Schweizer, Karin Nordenankar, Sultana Nilufar Jahan, Lina Emilsson, Åsa Wallén-Mackenzi. Reduced gene expression levels of Munc13-1 and additional components of the presynaptic exocytosis machinery upon conditional targeting of Vglut2 in the adolescent mouse. Synapse (New York, N.Y.). vol 68. issue 12. 2019-11-20. PMID:25139798. |
mice carrying a spatiotemporal restriction in the expression of the vesicular glutamate transporter 2 (vglut2; aka slc17a6) in the cortex, amygdala and hippocampal subiculum from the third postnatal week show a strong anxiolytic phenotype and certain behavioral correlates of schizophrenia. |
2019-11-20 |
2023-08-13 |
mouse |