| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mahdiyeh Faatehi, Mohsen Basiri, Akram Nezhadi, Mohammad Shabani, Yaser Masoumi-Ardakani, Zahra Soltani, Masoumeh Nozar. Early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by MK-801: Role of hippocampal BDNF. Brain research. vol 1711. 2020-08-04. PMID:30677409. |
early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by mk-801: role of hippocampal bdnf. |
2020-08-04 |
2023-08-13 |
rat |
| Mahdiyeh Faatehi, Mohsen Basiri, Akram Nezhadi, Mohammad Shabani, Yaser Masoumi-Ardakani, Zahra Soltani, Masoumeh Nozar. Early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by MK-801: Role of hippocampal BDNF. Brain research. vol 1711. 2020-08-04. PMID:30677409. |
this study aims to investigate the long-term effects of enriched environment (ee), which was imposed during the animals' development, on their recognition memory as well as hippocampal levels of brain-derived neurotrophic factor (bdnf), in an animal model of schizophrenia induced by chronic postnatal administration of mk-801. |
2020-08-04 |
2023-08-13 |
rat |
| Rick A Adams, Daniel Bush, Fanfan Zheng, Sofie S Meyer, Raphael Kaplan, Stelios Orfanos, Tiago Reis Marques, Oliver D Howes, Neil Burges. Impaired theta phase coupling underlies frontotemporal dysconnectivity in schizophrenia. Brain : a journal of neurology. vol 143. issue 4. 2020-07-31. PMID:32236540. |
in addition, an overlapping group of 33 schizophrenia and 29 control subjects underwent pet to measure the availability of gabaars expressing the α5 subunit (concentrated on hippocampal somatostatin interneurons). |
2020-07-31 |
2023-08-13 |
human |
| Andrew E Jaffe, Daniel J Hoeppner, Takeshi Saito, Lou Blanpain, Joy Ukaigwe, Emily E Burke, Leonardo Collado-Torres, Ran Tao, Katsunori Tajinda, Kristen R Maynard, Matthew N Tran, Keri Martinowich, Amy Deep-Soboslay, Joo Heon Shin, Joel E Kleinman, Daniel R Weinberger, Mitsuyuki Matsumoto, Thomas M Hyd. Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk. Nature neuroscience. vol 23. issue 4. 2020-07-07. PMID:32203495. |
of the ~9 million expression quantitative trait loci identified in the dg-gcl, 15% were not detected in bulk hippocampus, including 15 schizophrenia risk variants. |
2020-07-07 |
2023-08-13 |
human |
| Suzanne N Avery, Maureen McHugo, Kristan Armstrong, Jennifer U Blackford, Neil D Woodward, Stephan Hecker. Disrupted Habituation in the Early Stage of Psychosis. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 4. issue 11. 2020-07-03. PMID:31445881. |
preliminary evidence suggests that memory impairment is associated with failed hippocampal habituation in patients with chronic schizophrenia. |
2020-07-03 |
2023-08-13 |
Not clear |
| Roger Hudson, Justine Renard, Christopher Norris, Walter J Rushlow, Steven R Laviolett. Cannabidiol Counteracts the Psychotropic Side-Effects of Δ-9-Tetrahydrocannabinol in the Ventral Hippocampus through Bidirectional Control of ERK1-2 Phosphorylation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 44. 2020-06-29. PMID:31570536. |
the ventral hippocampus (vhipp) relays emotional salience via control of dopamine (da) neuronal activity states, which are dysregulated in psychosis and schizophrenia. |
2020-06-29 |
2023-08-13 |
Not clear |
| Florian Bitsch, Philipp Berger, Arne Nagels, Irina Falkenberg, Benjamin Straub. Impaired Right Temporoparietal Junction-Hippocampus Connectivity in Schizophrenia and Its Relevance for Generating Representations of Other Minds. Schizophrenia bulletin. vol 45. issue 4. 2020-06-29. PMID:30239972. |
despite recent work on healthy subjects suggesting that a coupling between the right temporoparietal junction (rtpj) and the hippocampus is relevant for building representations of others' intentions, the neural basis of related dysfunctions in patients with schizophrenia remains unclear. |
2020-06-29 |
2023-08-13 |
human |
| Lingfei Liu, Huaiting Gu, Fang Hou, Xinyan Xie, Xin Li, Bing Zhu, Jiajia Zhang, Wen-Hua Wei, Ranran Son. Dyslexia associated functional variants in Europeans are not associated with dyslexia in Chinese. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 180. issue 7. 2020-06-15. PMID:31264768. |
both esnps had supportive evidence of chromatin interactions observed in human hippocampus tissues and their respective target genes znf45 and dnah9 both had lower expression in brain tissues in schizophrenia patients than controls. |
2020-06-15 |
2023-08-13 |
human |
| Lingfei Liu, Huaiting Gu, Fang Hou, Xinyan Xie, Xin Li, Bing Zhu, Jiajia Zhang, Wen-Hua Wei, Ranran Son. Dyslexia associated functional variants in Europeans are not associated with dyslexia in Chinese. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 180. issue 7. 2020-06-15. PMID:31264768. |
in contrast, an esnp rs4234898 previously identified based on eqtl from the lymphoblastic cell lines of dyslexic children had no chromatin interaction with its target gene slc2a3 in hippocampus tissues and slc2a3 expressed higher in the schizophrenia patients than controls. |
2020-06-15 |
2023-08-13 |
human |
| Yu-Nu Ma, Ya-Xin Sun, Ting Wang, Han Wang, Yue Zhang, Yun-Ai Su, Ji-Tao Li, Tian-Mei S. Subchronic MK-801 treatment during adolescence induces long-term, not permanent, excitatory-inhibitory imbalance in the rat hippocampus. European journal of pharmacology. vol 867. 2020-06-08. PMID:31751575. |
however, it remains unclear how this treatment may affect e/i balance in hippocampus, which has long been associated with the pathophysiology of schizophrenia. |
2020-06-08 |
2023-08-13 |
rat |
| Stephanie M Perez, Jennifer J Donegan, Angela M Boley, David D Aguilar, Andrea Giuffrida, Daniel J Lodg. Ventral hippocampal overexpression of Cannabinoid Receptor Interacting Protein 1 (CNRIP1) produces a schizophrenia-like phenotype in the rat. Schizophrenia research. vol 206. 2020-05-19. PMID:30522798. |
previous studies have demonstrated aberrant cnrip1 dna promoter methylation in post-mortem in human patients with schizophrenia, and we have recently reported decreased methylation of the cnrip1 dna promoter in the ventral hippocampus (vhipp) of a rodent model of schizophrenia susceptibility. |
2020-05-19 |
2023-08-13 |
human |
| Lan-Xue Zhao, Yan-Hui Ge, Jia-Bing Li, Cai-Hong Xiong, Ping-Yee Law, Jian-Rong Xu, Yu Qiu, Hong-Zhuan Che. M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 5. 2020-05-12. PMID:30794430. |
m1 muscarinic receptors regulate the phosphorylation of ampa receptor subunit glua1 m1 muscarinic acetylcholine receptors are highly expressed in key areas that control cognition, such as the cortex and hippocampus, representing one potential therapeutic target for cognitive dysfunctions of alzheimer's disease and schizophrenia. |
2020-05-12 |
2023-08-13 |
Not clear |
| Tomas Monfil, Rubén Antonio Vázquez Roque, Israel Camacho-Abrego, Hiram Tendilla-Beltran, Tommaso Iannitti, Ivan Meneses-Morales, Patricia Aguilar-Alonso, Gonzalo Flores, Julio Cesar Morales-Medin. Correction to: Hyper-response to Novelty Increases c-Fos Expression in the Hippocampus and Prefrontal Cortex in a Rat Model of Schizophrenia. Neurochemical research. vol 43. issue 2. 2020-05-11. PMID:29332270. |
correction to: hyper-response to novelty increases c-fos expression in the hippocampus and prefrontal cortex in a rat model of schizophrenia. |
2020-05-11 |
2023-08-13 |
rat |
| Barbara Schwartz, Theresa Teslovich, Xiaozhen You, Jae Cho, Nina Schooler, Peter Kokkinos, Chandan Vaidy. An Exploratory Study of Exercise-related Effects on Memory and Hippocampal Connectivity in Schizophrenia. Clinical schizophrenia & related psychoses. 2020-05-07. PMID:29944414. |
an exploratory study of exercise-related effects on memory and hippocampal connectivity in schizophrenia. |
2020-05-07 |
2023-08-13 |
Not clear |
| Christin Weissleder, Hayley F North, Cynthia Shannon Weicker. Important unanswered questions about adult neurogenesis in schizophrenia. Current opinion in psychiatry. vol 32. issue 3. 2020-04-24. PMID:30762701. |
we highlight how alterations in signalling molecules in the local and peripheral environments in schizophrenia may regulate adult neurogenesis in the human subgranular zone of the hippocampus and the subependymal zone (sez). |
2020-04-24 |
2023-08-13 |
human |
| David J Clarke, Tariq W Chohan, Mustafa S Kassem, Kristie L Smith, Rose Chesworth, Tim Karl, Michael P Kuligowski, Sandra Y Fok, Maxwell R Bennett, Jonathon C Arnol. Neuregulin 1 Deficiency Modulates Adolescent Stress-Induced Dendritic Spine Loss in a Brain Region-Specific Manner and Increases Complement 4 Expression in the Hippocampus. Schizophrenia bulletin. vol 45. issue 2. 2020-04-06. PMID:29566220. |
one neuropathological feature of schizophrenia is a diminished number of dendritic spines in the prefrontal cortex and hippocampus. |
2020-04-06 |
2023-08-13 |
mouse |
| Zheng-Li Fan, Bing Wu, Guang-Yan Wu, Juan Yao, Xuan Li, Ke-Hui Hu, Zhen-Hua Zhou, Jian-Feng Su. Optogenetic inhibition of ventral hippocampal neurons alleviates associative motor learning dysfunction in a rodent model of schizophrenia. PloS one. vol 14. issue 12. 2020-04-02. PMID:31891640. |
optogenetic inhibition of ventral hippocampal neurons alleviates associative motor learning dysfunction in a rodent model of schizophrenia. |
2020-04-02 |
2023-08-13 |
rat |
| Steven J Girdler, Jamie E Confino, Mary E Woesne. Exercise as a Treatment for Schizophrenia: A Review. Psychopharmacology bulletin. vol 49. issue 1. 2020-03-30. PMID:30858639. |
although no clear etiology of schizophrenia has been discovered, many factors have been identified that contribute to the development of the disease, such as neurotransmitter alterations, decreased synaptic plasticity, and diminished hippocampal volume. |
2020-03-30 |
2023-08-13 |
Not clear |
| Steven J Girdler, Jamie E Confino, Mary E Woesne. Exercise as a Treatment for Schizophrenia: A Review. Psychopharmacology bulletin. vol 49. issue 1. 2020-03-30. PMID:30858639. |
historically, antipsychotic medications have targeted biochemical alterations in the brains of patients with schizophrenia but have been ineffective in alleviating cognitive and hippocampal deficits. |
2020-03-30 |
2023-08-13 |
Not clear |
| Steven J Girdler, Jamie E Confino, Mary E Woesne. Exercise as a Treatment for Schizophrenia: A Review. Psychopharmacology bulletin. vol 49. issue 1. 2020-03-30. PMID:30858639. |
exercise therapy has been shown to improve positive and negative symptoms, quality of life, cognition, and hippocampal plasticity, and to increase hippocampal volume in the brains of patients with schizophrenia. |
2020-03-30 |
2023-08-13 |
Not clear |