| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liesbeth A Bruins Slot, Fabrice Lestienne, Catherine Grevoz-Barret, Adrian Newman-Tancredi, Didier Cussa. F15063, a potential antipsychotic with dopamine D(2)/D(3) receptor antagonist and 5-HT(1A) receptor agonist properties: influence on immediate-early gene expression in rat prefrontal cortex and striatum. European journal of pharmacology. vol 620. issue 1-3. 2009-12-31. PMID:19695244. |
f15063 (10 mg/kg) and clozapine (10 mg/kg), but not haloperidol (0.63 mg/kg), induced c-fos and fosb mrna expression in prefrontal cortex, a region associated with control of cognition and negative symptoms of schizophrenia. |
2009-12-31 |
2023-08-12 |
rat |
| Aygun Ertugrul, Bilge Volkan-Salanci, Koray Basar, Kader Karli Oguz, Basaran Demir, Eser Lay Ergun, Senem Senturk, Belkis Erbas, Aysenur Cila, Berna Ulu. The effect of clozapine on regional cerebral blood flow and brain metabolite ratios in schizophrenia: relationship with treatment response. Psychiatry research. vol 174. issue 2. 2009-12-29. PMID:19837567. |
the effect of clozapine on regional cerebral blood flow and brain metabolite ratios in schizophrenia: relationship with treatment response. |
2009-12-29 |
2023-08-12 |
Not clear |
| Eliza Martha de Paiva Barretto, Monica Kayo, Belquiz S Avrichir, Antonio Reis Sa, Maria das Gracas Miquelutti Camargo, Isabel Cristina Napolitano, Fabiano Gonçalves Nery, Jony Arrais Pinto, Silvia Bannwart, Silvia Scemes, Elaine Di Sarno, Helio Elki. A preliminary controlled trial of cognitive behavioral therapy in clozapine-resistant schizophrenia. The Journal of nervous and mental disease. vol 197. issue 11. 2009-12-28. PMID:19996727. |
the aim of this study was to compare the efficacy of cbt to a befriending (bf) control group in patients with schizophrenia who are refractory to clozapine. |
2009-12-28 |
2023-08-12 |
Not clear |
| L Terenius, A Wahlström, L Lindström, E Widerlö. Increased CSF levels of endorphines in chronic psychosis. Neuroscience letters. vol 3. issue 3. 2009-12-15. PMID:19604879. |
four cases with chronic schizophrenia were studied before and after treatment with the antipsychotic agent clozapine (leponex). |
2009-12-15 |
2023-08-12 |
Not clear |
| Anand Mattai, Lawrence Fung, Jennifer Bakalar, Gerald Overman, Julia Tossell, Rachel Miller, Judith Rapoport, Nitin Gogta. Adjunctive use of lithium carbonate for the management of neutropenia in clozapine-treated children. Human psychopharmacology. vol 24. issue 7. 2009-12-09. PMID:19743394. |
clozapine, a dibenzodiazepine antipsychotic, is the most effective medication for treatment-resistant schizophrenia. |
2009-12-09 |
2023-08-12 |
Not clear |
| David de Lucena, Brisa Simões Fernandes, Michael Berk, Seetal Dodd, Dalton W Medeiros, Mariana Pedrini, Mauricio Kunz, Fabiano Alves Gomes, Larriany F Giglio, Maria Inês Lobato, Paulo Silva Belmonte-de-Abreu, Clarissa Severino Gam. Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. The Journal of clinical psychiatry. vol 70. issue 10. 2009-11-23. PMID:19906345. |
improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. |
2009-11-23 |
2023-08-12 |
Not clear |
| David de Lucena, Brisa Simões Fernandes, Michael Berk, Seetal Dodd, Dalton W Medeiros, Mariana Pedrini, Mauricio Kunz, Fabiano Alves Gomes, Larriany F Giglio, Maria Inês Lobato, Paulo Silva Belmonte-de-Abreu, Clarissa Severino Gam. Improvement of negative and positive symptoms in treatment-refractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. The Journal of clinical psychiatry. vol 70. issue 10. 2009-11-23. PMID:19906345. |
the aim of this study was to examine the efficacy of memantine as an adjunctive treatment to clozapine in patients with refractory schizophrenia. |
2009-11-23 |
2023-08-12 |
Not clear |
| Donald C Gof. Review: lamotrigine may be an effective treatment for clozapine resistant schizophrenia. Evidence-based mental health. vol 12. issue 4. 2009-11-04. PMID:19854773. |
review: lamotrigine may be an effective treatment for clozapine resistant schizophrenia. |
2009-11-04 |
2023-08-12 |
Not clear |
| Azizah Attard, Fiona Gaughra. Review: limited evidence that adding a second antipsychotic improves clozapine treatment in schizophrenia. Evidence-based mental health. vol 12. issue 4. 2009-11-04. PMID:19854774. |
review: limited evidence that adding a second antipsychotic improves clozapine treatment in schizophrenia. |
2009-11-04 |
2023-08-12 |
Not clear |
| Antonio R Sa, Ana G Hounie, Aline S Sampaio, Jony Arrais, Euripedes C Miguel, Helio Elki. Obsessive-compulsive symptoms and disorder in patients with schizophrenia treated with clozapine or haloperidol. Comprehensive psychiatry. vol 50. issue 5. 2009-11-02. PMID:19683614. |
obsessive-compulsive symptoms and disorder in patients with schizophrenia treated with clozapine or haloperidol. |
2009-11-02 |
2023-08-12 |
human |
| Antonio R Sa, Ana G Hounie, Aline S Sampaio, Jony Arrais, Euripedes C Miguel, Helio Elki. Obsessive-compulsive symptoms and disorder in patients with schizophrenia treated with clozapine or haloperidol. Comprehensive psychiatry. vol 50. issue 5. 2009-11-02. PMID:19683614. |
we conducted a cross-sectional study to compare the prevalence and severity of obsessive-compulsive symptoms (ocss) and obsessive-compulsive disorder (ocd) in patients with schizophrenia treated with clozapine or haloperidol. |
2009-11-02 |
2023-08-12 |
human |
| Antonio R Sa, Ana G Hounie, Aline S Sampaio, Jony Arrais, Euripedes C Miguel, Helio Elki. Obsessive-compulsive symptoms and disorder in patients with schizophrenia treated with clozapine or haloperidol. Comprehensive psychiatry. vol 50. issue 5. 2009-11-02. PMID:19683614. |
schizophrenia patients taking clozapine had higher severity scores both in obsessive-compulsive and schizophrenia rating scales. |
2009-11-02 |
2023-08-12 |
human |
| Kirsi-Maria Haapasalo-Pes. [Clozapine in the treatment of under-age schizophrenia]. Duodecim; laaketieteellinen aikakauskirja. vol 125. issue 15. 2009-10-29. PMID:19769179. |
[clozapine in the treatment of under-age schizophrenia]. |
2009-10-29 |
2023-08-12 |
human |
| Kirsi-Maria Haapasalo-Pes. [Clozapine in the treatment of under-age schizophrenia]. Duodecim; laaketieteellinen aikakauskirja. vol 125. issue 15. 2009-10-29. PMID:19769179. |
according to the treatment practice for adults, clozapine emerges inevitably as a drug option for difficult-to-manage schizophrenia in an under-aged person. |
2009-10-29 |
2023-08-12 |
human |
| Kent E Jardemark, Asa Konradsson, Björn Schilström, Monica M Marcus, Torgny H Svensso. Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19582782. |
treatment with topiramate may improve negative symptoms in schizophrenia when added to typical antipsychotic drugs (apds) but not to clozapine. |
2009-10-26 |
2023-08-12 |
rat |
| Edgardo Carrizo, Virginia Fernández, Lisette Connell, Ignacio Sandia, Dexy Prieto, Johana Mogollón, Dennys Valbuena, Iliana Fernández, Enma Araujo de Baptista, Trino Baptist. Extended release metformin for metabolic control assistance during prolonged clozapine administration: a 14 week, double-blind, parallel group, placebo-controlled study. Schizophrenia research. vol 113. issue 1. 2009-10-12. PMID:19515536. |
clozapine is the most effective agent in treatment-resistant schizophrenia. |
2009-10-12 |
2023-08-12 |
Not clear |
| Emilio Sacchetti, Alessandro Galluzzo, Paolo Valsecchi, Fabio Romeo, Barbara Gorini, Lewis Warringto. Ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the MOZART study. Schizophrenia research. vol 113. issue 1. 2009-10-12. PMID:19606529. |
ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the mozart study. |
2009-10-12 |
2023-08-12 |
Not clear |
| Emilio Sacchetti, Alessandro Galluzzo, Paolo Valsecchi, Fabio Romeo, Barbara Gorini, Lewis Warringto. Ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the MOZART study. Schizophrenia research. vol 113. issue 1. 2009-10-12. PMID:19606529. |
this 18-week, randomized, flexible-dose, double-blind, double-dummy trial evaluated ziprasidone as an alternative to clozapine in treatment-refractory schizophrenia patients. |
2009-10-12 |
2023-08-12 |
Not clear |
| Emilio Sacchetti, Alessandro Galluzzo, Paolo Valsecchi, Fabio Romeo, Barbara Gorini, Lewis Warringto. Ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the MOZART study. Schizophrenia research. vol 113. issue 1. 2009-10-12. PMID:19606529. |
in conclusion, this trial indicates that both ziprasidone and clozapine, having comparable efficacy coupled with satisfactory general safety and tolerability, may be regarded as valuable options for the short-term treatment of difficult-to-treat schizophrenia patients with a history of multiple resistance and/or intolerance to antipsychotics. |
2009-10-12 |
2023-08-12 |
Not clear |
| Z J Daskalakis, T P Georg. Clozapine, GABA(B), and the treatment of resistant schizophrenia. Clinical pharmacology and therapeutics. vol 86. issue 4. 2009-10-09. PMID:19626000. |
clozapine, gaba(b), and the treatment of resistant schizophrenia. |
2009-10-09 |
2023-08-12 |
Not clear |