| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David C Henderson, Bikash Sharma, Xiaoduo Fan, Paul M Copeland, Christina P Borba, Oliver Freudenreich, Corinne Cather, A Eden Evins, Donald C Gof. Dietary saturated fat intake and glucose metabolism impairments in nondiabetic, nonobese patients with schizophrenia on clozapine or risperidone. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 22. issue 1. 2010-06-24. PMID:20196981. |
the goal of this study was to understand the relationship between clozapine and risperidone with glucose and lipid metabolism and dietary fat intake in patients with schizophrenia. |
2010-06-24 |
2023-08-12 |
Not clear |
| Renan P Souza, Vincenzo de Luca, Herbert Y Meltzer, Jeffrey A Lieberman, James L Kenned. Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia. Pharmacogenetics and genomics. vol 20. issue 4. 2010-06-18. PMID:20168265. |
influence of serotonin 3a and 3b receptor genes on clozapine treatment response in schizophrenia. |
2010-06-18 |
2023-08-12 |
Not clear |
| Renan P Souza, Vincenzo de Luca, Herbert Y Meltzer, Jeffrey A Lieberman, James L Kenned. Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia. Pharmacogenetics and genomics. vol 20. issue 4. 2010-06-18. PMID:20168265. |
in this study, we further investigated the role of the subunits a and b of the htr3 receptor using 140 schizophrenia patients taking clozapine for 6 months. |
2010-06-18 |
2023-08-12 |
Not clear |
| Renan P Souza, Vincenzo de Luca, Herbert Y Meltzer, Jeffrey A Lieberman, James L Kenned. Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia. Pharmacogenetics and genomics. vol 20. issue 4. 2010-06-18. PMID:20168265. |
taken together, our results suggest that variants in the htr3a receptor gene can play a role in the treatment outcome of clozapine in schizophrenia patients that are refractory or intolerant of typical antipsychotic therapy. |
2010-06-18 |
2023-08-12 |
Not clear |
| Anna Dietrich-Muszalska, Jolanta Rabe-Jablonska, Pawel Nowak, Bogdan Konte. The first- and second-generation antipsychotic drugs affect ADP-induced platelet aggregation. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 11. issue 2 Pt 2. 2010-06-14. PMID:20218792. |
the effects of antipsychotic drugs on blood platelet function are not fully explained, therefore the purpose of the present study was to examine and compare the effects of the second-generation antipsychotic drugs used in schizophrenia (clozapine, risperidone and olanzapine), with the effects of the first generation antipsychotic, haloperidol, on the platelet aggregation induced by adp in vitro. |
2010-06-14 |
2023-08-12 |
Not clear |
| Nilufar Mossaheb, Christoph Spindelegger, Susanne Asenbaum, Peter Fischer, Christian Barna. Favourable results in treatment-resistant schizophrenic patients under combination of aripiprazole with clozapine. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 11. issue 2 Pt 2. 2010-06-14. PMID:20218805. |
clozapine is still the gold standard in treatment-resistant schizophrenia. |
2010-06-14 |
2023-08-12 |
Not clear |
| Chikezie Eseonu, Jon Carlso. Clozapine rechallenge in refractory schizophrenia. The American journal of psychiatry. vol 167. issue 5. 2010-05-17. PMID:20439404. |
clozapine rechallenge in refractory schizophrenia. |
2010-05-17 |
2023-08-12 |
Not clear |
| William V Bobo, Karuna Jayathilake, Myung A Lee, Herbert Y Meltze. Changes in weight and body mass index during treatment with melperone, clozapine and typical neuroleptics. Psychiatry research. vol 176. issue 2-3. 2010-05-14. PMID:20199813. |
weight and bmi were retrospectively compared in patients with schizophrenia treated with melperone (n=34), clozapine (n=225), or typical neuroleptics (n=74) for up to 3 months. |
2010-05-14 |
2023-08-12 |
Not clear |
| William V Bobo, Karuna Jayathilake, Myung A Lee, Herbert Y Meltze. Changes in weight and body mass index during treatment with melperone, clozapine and typical neuroleptics. Psychiatry research. vol 176. issue 2-3. 2010-05-14. PMID:20199813. |
because of the relationship between bmi and cardiovascular risk, melperone deserves further study as both a first line treatment and as an alternative to clozapine in refractory schizophrenia. |
2010-05-14 |
2023-08-12 |
Not clear |
| Jörgen Ekström, Tania Godoy, Alessandro Riv. N-Desmethylclozapine exerts dual and opposite effects on salivary secretion in the rat. European journal of oral sciences. vol 118. issue 1. 2010-05-10. PMID:20156258. |
n-desmethylclozapine is a major metabolite of the atypical antipsychotic drug clozapine, used in the treatment of therapy-resistant schizophrenia. |
2010-05-10 |
2023-08-12 |
rat |
| Gin Malhi, Danielle Adams, Janice Plain, Carissa Coulston, Michael Herman, Garry Walte. Clozapine and cardiometabolic health in chronic schizophrenia: correlations and consequences in a clinical context. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. vol 18. issue 1. 2010-04-28. PMID:20039791. |
clozapine and cardiometabolic health in chronic schizophrenia: correlations and consequences in a clinical context. |
2010-04-28 |
2023-08-12 |
Not clear |
| David T Chau, Danielle Gulick, Haiyi Xie, Ree Dawson, Alan I Gree. Clozapine chronically suppresses alcohol drinking in Syrian golden hamsters. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19895824. |
the ability of clozapine to suppress alcohol drinking in the hamster over an extended period of time without suppressing sucrose, water, or food consumption is consistent with preliminary reports indicating that clozapine limits frequent alcohol use, even producing abstinence in many patients with schizophrenia. |
2010-04-13 |
2023-08-12 |
Not clear |
| Deanna L Kelly, Robert P McMahon, Fang Liu, Raymond C Love, Heidi J Wehring, Joo-Cheol Shim, Kimberly R Warren, Robert R Conle. Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. The Journal of clinical psychiatry. vol 71. issue 3. 2010-04-08. PMID:20079332. |
cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. |
2010-04-08 |
2023-08-12 |
Not clear |
| Dragan B Ravanic, Slavica M Djukic Dejanovic, Vladimir Janjic, Suzana D Jovic, Dragan R Milovanovic, Vladimir Jakovljevic, Vesna Pantovic, Boris Ravanic, Maja Pantovic, Mihailo M Pantovi. Effectiveness of clozapine, haloperidol and chlorpromazine in schizophrenia during a five-year period. Arquivos de neuro-psiquiatria. vol 67. issue 2A. 2010-04-06. PMID:19547808. |
effectiveness of clozapine, haloperidol and chlorpromazine in schizophrenia during a five-year period. |
2010-04-06 |
2023-08-12 |
Not clear |
| J Ekström, T Godoy, A Riv. Clozapine: agonistic and antagonistic salivary secretory actions. Journal of dental research. vol 89. issue 3. 2010-03-26. PMID:20093673. |
individuals receiving clozapine treatment for schizophrenia complain of drooling. |
2010-03-26 |
2023-08-12 |
rat |
| L V Rao, M L Snyder, G M Vallar. Rapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum. Journal of clinical laboratory analysis. vol 23. issue 6. 2010-03-18. PMID:19927349. |
clozapine is indicated for the treatment of schizophrenia and related psychotic disorders. |
2010-03-18 |
2023-08-12 |
human |
| Shamim Hashemi Nejad, Rajesh T Gandhi, Oliver Freudenreic. Clozapine use in HIV-infected schizophrenia patients: a case-based discussion and review. Psychosomatics. vol 50. issue 6. 2010-03-17. PMID:19996235. |
clozapine use in hiv-infected schizophrenia patients: a case-based discussion and review. |
2010-03-17 |
2023-08-12 |
Not clear |
| David de Lucena, Brisa Simões Fernandes, Mauricio Kunz, Gabriel Rodrigo Fries, Laura Stertz, Bianca Aguiar, Bianca Pfaffenseller, Clarissa Severino Gam. Lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine. The Journal of clinical psychiatry. vol 71. issue 1. 2010-03-01. PMID:20129011. |
lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine. |
2010-03-01 |
2023-08-12 |
Not clear |
| Michael Myslobodsk. Ingenuity pathway analysis of clozapine-induced obesity. Obesity facts. vol 1. issue 2. 2010-02-26. PMID:20054168. |
lipid accretion is one of the major side effects of clozapine pharmacotherapy of schizophrenia that made clozapine into an interesting obesity drug model. |
2010-02-26 |
2023-08-12 |
Not clear |
| Anand Mattai, Alex Chavez, Deanna Greenstein, Liv Clasen, Jennifer Bakalar, Reva Stidd, Judith Rapoport, Nitin Gogta. Effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia. Schizophrenia research. vol 116. issue 1. 2010-02-24. PMID:19913390. |
effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia. |
2010-02-24 |
2023-08-12 |
Not clear |