| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lorenzo Pelizza, Emanuela Leuci, Davide Maestri, Emanuela Quattrone, Silvia Azzali, Giuseppina Paulillo, Pietro Pellegrini, Andrea Raball. Disorganization in first episode schizophrenia: Treatment response and psychopathological findings from the 2-year follow-up of the "Parma Early Psychosis" program. Journal of psychiatric research. vol 141. 2021-08-25. PMID:34274840. |
therefore, the aims of this research were (1) to monitor the longitudinal stability of disorganized symptoms in young patients with first episode schizophrenia (fes) along a 2-year follow-up period, and (2) to examine any significant association of disorganization with functioning, psychopathology and the specific treatment components of an "early intervention in psychosis" (eip) program across the 2 years of follow-up. |
2021-08-25 |
2023-08-13 |
Not clear |
| Anna Sergeevna Piatoikina, Anastasia Alexandrovna Lyakhova, Ilya Vladimirovich Semennov, Tatyana Vladimirovna Zhilyaeva, Olga Vladimirovna Kostina, Ekaterina Sergeevna Zhukova, Tatyana Grigorievna Shcherbatyuk, Evgeny Dmitrievich Kasyanov, Anna Sergeevna Blagonravova, Galina Elevna Maz. Association of antioxidant deficiency and the level of products of protein and lipid peroxidation in patients with the first episode of schizophrenia. Journal of molecular neuroscience : MN. 2021-08-19. PMID:34410570. |
the present study was undertaken to compare the levels of oxidative stress markers in the peripheral blood of patients with a first episode of schizophrenia (fes) and in healthy volunteers (hv). |
2021-08-19 |
2023-08-13 |
human |
| Xusan Xu, Shucun Luo, Xia Wen, Xiaoxia Wang, Jingwen Yin, Xudong Luo, Bin He, Chunmei Liang, Susu Xiong, Dongjian Zhu, Jiawu Fu, Dong Lv, Zhun Dai, Juda Lin, You Li, Zhixiong Lin, Wubiao Chen, Zebin Luo, Yajun Wang, Guoda M. Genetic Contribution of Synapse-Associated Protein 97 to Orbitofrontal-Striatal-Thalamic Circuitry Connectivity Changes in First-Episode Schizophrenia. Frontiers in psychiatry. vol 12. 2021-08-06. PMID:34349683. |
this study tested whether synapse-associated protein 97 (sap97), a reasonable candidate gene for schizophrenia, is related to orbitofrontal-striatal-thalamic connection changes in first-episode schizophrenia (fes) patients and the clinical performance of schizophrenic patients by affecting this integrity. |
2021-08-06 |
2023-08-13 |
human |
| Ernest Tyburski, Piotr Podwalski, Katarzyna Waszczuk, Katarzyna Rek-Owodziń, Monika Mak, Piotr Plichta, Maksymilian Bielecki, Krzysztof Rudkowski, Michał Szelepajło, Jolanta Kucharska-Mazur, Wojciech Andrusewicz, Błażej Misiak, Magdalena Kerestey, Adrianna Bober, Krzysztof Wietrzyński, Anna Michalczyk, Magdalena Więdłocha, Piotr Marcinowicz, Jerzy Samochowiec, Leszek Saga. Relationship of Corpus Callosum Integrity with Working Memory, Planning, and Speed of Processing in Patients with First-Episode and Chronic Schizophrenia. Journal of clinical medicine. vol 10. issue 14. 2021-07-29. PMID:34300325. |
there is a paucity of reports examining the relationship between the integrity of the corpus callosum (cc) and different aspects of cognitive functioning in patients with first-episode (fes) and chronic schizophrenia (cs) simultaneously; furthermore, what results exist are inconclusive. |
2021-07-29 |
2023-08-13 |
Not clear |
| Petros Drosos, Kolbjørn Brønnick, Inge Joa, Jan Olav Johannessen, Erik Johnsen, Rune Andreas Kroken, Helen Joy Stain, Wenche Ten Velden Hegelstad, Tor Ketil Larse. One-Year Outcome and Adherence to Pharmacological Guidelines in First-Episode Schizophrenia: Results From a Consecutive Cohort Study. Journal of clinical psychopharmacology. vol 40. issue 6. 2021-07-26. PMID:33136922. |
this study investigated the 1-year outcome and the application of the guidelines for the pharmacological treatment of nonremitted first-episode schizophrenia (fes) patients during the first year of follow-up. |
2021-07-26 |
2023-08-13 |
Not clear |
| Viswam Subeesh, Eswaran Maheswari, Hemendra Singh, Ganesan Rajalekshmi Saraswathy, Neha Reddy, Pudi Chiranjeev. Early prediction of clinical response in first episode schizophrenia (FES) patients receiving olanzapine. International journal of psychiatry in clinical practice. vol 24. issue 3. 2021-07-09. PMID:32338556. |
early prediction of clinical response in first episode schizophrenia (fes) patients receiving olanzapine. |
2021-07-09 |
2023-08-13 |
Not clear |
| Michael Maes, Aristo Vojdani, Sunee Sirivichayakul, Decio S Barbosa, Buranee Kanchanatawa. Inflammatory and Oxidative Pathways Are New Drug Targets in Multiple Episode Schizophrenia and Leaky Gut, Klebsiella pneumoniae, and C1q Immune Complexes Are Additional Drug Targets in First Episode Schizophrenia. Molecular neurobiology. vol 58. issue 7. 2021-07-06. PMID:33675500. |
the aim of this study was to delineate (a) the differences in these pathways between stable-phase, first (fes) and multiple (mes) episode schizophrenia and (b) the pathways that determine the behavioral-cognitive-physical-psychosocial (bcps) deterioration in fes/mes. |
2021-07-06 |
2023-08-13 |
Not clear |
| David Fraguas, Covadonga M Díaz-Caneja, Laura Pina-Camacho, Inge Winter van Rossum, Lone Baandrup, Iris E Sommer, Birte Glenthøj, René S Kahn, Stefan Leucht, Celso Arang. The role of depression in the prediction of a "late" remission in first-episode psychosis: An analysis of the OPTiMiSE study. Schizophrenia research. vol 231. 2021-07-05. PMID:33838518. |
the identification of predictors of psychosis remission could guide early clinical decision-making for treatment of first-episode schizophrenia (fes). |
2021-07-05 |
2023-08-13 |
Not clear |
| Chencai Wang, Talia Oughourlian, Todd A Tishler, Faizan Anwar, Catalina Raymond, Alex D Pham, Abby Perschon, J Pablo Villablanca, Joseph Ventura, Kenneth L Subotnik, Keith H Nuechterlein, Benjamin M Ellingso. Cortical morphometric correlational networks associated with cognitive deficits in first episode schizophrenia. Schizophrenia research. vol 231. 2021-07-05. PMID:33872855. |
several brain structures associated with the seven performance domains evaluated using the matrics (measurement and treatment research to improve cognition in schizophrenia) consensus cognitive battery (mccb) have shown cortical volume loss in first episode schizophrenia (fes) patients. |
2021-07-05 |
2023-08-13 |
Not clear |
| Xuan Li, Xiaoyun Guo, Xiaoduo Fan, Tienan Feng, Chuanyue Wang, Zhijian Yao, Xiufeng Xu, Zhiyu Chen, Huiling Wang, Shoufu Xie, Jiangjiang He, Kaiming Zhuo, Qiong Xiang, Haixin Cen, Jinhong Wang, Robert C Smith, Hua Jin, Matcheri S Keshavan, Stephen R Marder, John M Davis, Kaida Jiang, Yifeng Xu, Dengtang Li. Sequential Multiple-Assignment Randomized Trials to Compare Antipsychotic Treatments (SMART-CAT) in first-episode schizophrenia patients: Rationale and trial design. Schizophrenia research. vol 230. 2021-07-02. PMID:33279374. |
accumulated studies have investigated pharmacological interventions for first-episode schizophrenia (fes) patients. |
2021-07-02 |
2023-08-13 |
human |
| Sugai Liang, Qiang Wang, Andrew J Greenshaw, Xiaojing Li, Wei Deng, Hongyan Ren, Chengcheng Zhang, Hua Yu, Wei Wei, Yamin Zhang, Mingli Li, Liansheng Zhao, Xiangdong Du, Yajing Meng, Xiaohong Ma, Chao-Gan Yan, Tao L. Aberrant triple-network connectivity patterns discriminate biotypes of first-episode medication-naive schizophrenia in two large independent cohorts. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 8. 2021-06-28. PMID:33408329. |
the study sample comprised 300 first-episode antipsychotic-naive patients with schizophrenia (fes) and 301 healthy controls (hcs). |
2021-06-28 |
2023-08-13 |
human |
| Martin J Dietz, Yuan Zhou, Lotte Veddum, Christopher D Frith, Vibeke F Blikste. Aberrant effective connectivity is associated with positive symptoms in first-episode schizophrenia. NeuroImage. Clinical. vol 28. 2021-06-25. PMID:33039973. |
to address this question, we used fmri and dynamic causal modelling (dcm) to test for abnormal brain connectivity in twenty-four patients with first-episode schizophrenia (fes) compared to twenty-five matched controls performing the human connectome project (hcp) social cognition paradigm. |
2021-06-25 |
2023-08-13 |
human |
| Tingting Zhang, Yamei Tang, Xiudeng Yang, Xuyi Wang, Shan Ding, Kai Huang, Yong Liu, Bing Lan. Expression of GSK3β, PICK1, NEFL, C4, NKCC1 and Synaptophysin in peripheral blood mononuclear cells of the first-episode schizophrenia patients. Asian journal of psychiatry. vol 55. 2021-06-21. PMID:33373836. |
in this study, 41 first-episode schizophrenia (fes) patients and 44 healthy controls (hc) were recruited and the expression of six genes commonly relevant to synaptic functions was examined in the peripheral blood mononuclear cells (pbmcs). |
2021-06-21 |
2023-08-13 |
Not clear |
| Hans J Søgaard, Mikkel Højlund, Anja Elliott, Anne G Viuff, Kirsten Vandborg, Jakob Viuff, Povl Munk-Jørgensen, Peter Hjort. Effect of a 30-Month Health-Promoting Program on the Prevalence of Cardiovascular Risk Factors in Patients With First Episode Schizophrenia. American journal of therapeutics. vol 27. issue 5. 2021-06-18. PMID:30677004. |
lifestyle interventions aimed at reducing cardiovascular risk factors in patients with first-episode schizophrenia (fes) have shown modest efficacy, probably owing to a short observation period and the presumption of linear trajectories of cardiovascular risk factors. |
2021-06-18 |
2023-08-13 |
Not clear |
| Alp Üçok, İlayda Arjen Kar. Relapse rates following antipsychotic discontinuation in the maintenance phase after first-episode of schizophrenia: Results of a long-term follow-up study. Schizophrenia research. vol 225. 2021-06-17. PMID:31653578. |
when the antipsychotic treatment should be discontinued after first-episode of schizophrenia (fes) in patients who had a good response to initial treatment is still controversial. |
2021-06-17 |
2023-08-13 |
Not clear |
| Michelle A Worthington, Eva Petkova, Oliver Freudenreich, Corrine Cather, Daphne Holt, Iruma Bello, Erica Diminich, Yingying Tang, Babak A Ardekani, Botao Zeng, Renrong Wu, Xiaoduo Fan, Jingping Zhao, Jijun Wang, Donald C Gof. Air pollution and hippocampal atrophy in first episode schizophrenia. Schizophrenia research. vol 218. 2021-06-17. PMID:32169403. |
hippocampal atrophy in individuals with first episode schizophrenia (fes) has also been associated with biomarkers of inflammation and oxidative stress, whereas hippocampal atrophy was not observed in matched healthy controls with similar biomarker levels of inflammation and oxidative stress. |
2021-06-17 |
2023-08-13 |
human |
| Lorenzo Pelizza, Clara Pellegrini, Emanuela Quattrone, Silvia Azzali, Giulia Landi, Pietro Pellegrini, Emanuela Leuc. Suicidal Thinking and Behavior in First Episode Schizophrenia: Findings from the 24-Month Follow-Up of the "Parma Early Psychosis" Program. Archives of suicide research : official journal of the International Academy for Suicide Research. 2021-05-26. PMID:32970972. |
although suicide risk is relevant in first episode schizophrenia (fes), little data are reported on suicidal ideation and its longitudinal stability. |
2021-05-26 |
2023-08-13 |
human |
| Wei Qi, Esther Blessing, Chenxiang Li, Babak A Ardekani, Kamber L Hart, Julia Marx, Oliver Freudenreich, Corinne Cather, Daphne Holt, Iruma Bello, Erica D Diminich, Yingying Tang, Michelle Worthington, Botao Zeng, Renrong Wu, Xiaoduo Fan, Andrea Troxel, Jingping Zhao, Jijun Wang, Donald C Gof. Effect of citalopram on hippocampal volume in first-episode schizophrenia: Structural MRI results from the DECIFER trial. Psychiatry research. Neuroimaging. vol 312. 2021-05-20. PMID:33857750. |
hippocampal volume loss is prominent in first episode schizophrenia (fes) and has been associated with poor clinical outcomes and with bdnf genotype; antidepressants are believed to reverse hippocampal volume loss via release of bdnf. |
2021-05-20 |
2023-08-13 |
Not clear |
| Huimei An, Jun Qin, Hongzhen Fan, Fengmei Fan, Shuping Tan, Zhiren Wang, Jing Shi, Fude Yang, Yunlong Tan, Xu-Feng Huan. Decreased serum NCAM is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients. Journal of psychiatric research. vol 131. 2021-05-14. PMID:32950707. |
this study investigated the relationship between the serum ncam concentrations and hippocampal volume and psychotic symptoms in first-episode drug naïve schizophrenia (fes) patients. |
2021-05-14 |
2023-08-13 |
Not clear |
| Angelica Silva, Roberto Limongi, Michael MacKinley, Lena Palaniyappa. Small Words That Matter: Linguistic Style and Conceptual Disorganization in Untreated First-Episode Schizophrenia. Schizophrenia bulletin open. vol 2. issue 1. 2021-05-04. PMID:33937775. |
this study aimed to shed light on the linguistic style affecting the communication discourse in first-episode schizophrenia (fes) by investigating the analytic thinking index in relation to clinical scores of conceptual and thought disorganization (positive and negative syndrome scale, panss-p2 and thought and language index, tli). |
2021-05-04 |
2023-08-13 |
human |