| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting Yat Wong, Sherry Kit Wa Chan, Charlton Cheung, Christy Lai Ming Hui, Yi Nam Suen, Wing Chung Chang, Edwin Ho Ming Lee, Eric Yu Hai Che. Dynamic Patterns of Symptoms and Functioning in Predicting Deliberate Self-harm in Patients with First-Episode Schizophrenia-Spectrum Disorders Over 3 Years. Schizophrenia bulletin. 2022-06-11. PMID:35689554. |
we aimed to explore the dynamic relationship between symptomatology, functioning and deliberate self-harm (dsh) and evaluate the feasibility of developing a self-harm risk prediction tool for patients with first-episode schizophrenia (fes). |
2022-06-11 |
2023-08-14 |
Not clear |
| Liu Yuan, Xiaoqian Ma, David Li, Zongchang Li, Lijun Ouyang, Lejia Fan, Zihao Yang, Zhenmei Zhang, Chunwang Li, Ying He, Xiaogang Che. Abnormal Brain Network Interaction Associated With Positive Symptoms in Drug-Naive Patients With First-Episode Schizophrenia. Frontiers in psychiatry. vol 13. 2022-06-03. PMID:35656348. |
we constructed two brain functional networks based on the positive and negative correlations between positive symptom scores and brain connectivity in drug-naive patients with first-episode schizophrenia (fes, |
2022-06-03 |
2023-08-14 |
Not clear |
| Wenjun Su, Zexin Zhao, Guanjun Li, Xiaochen Tang, Lihua Xu, Yingying Tang, Yanyan Wei, Huiru Cui, Tianhong Zhang, Jie Zhang, Xiaohua Liu, Qian Guo, Jijun Wan. Thalamo-hippocampal dysconnectivity is associated with serum cholesterol level in drug-naïve patients with first-episode schizophrenia. Journal of psychiatric research. vol 151. 2022-05-27. PMID:35623125. |
a total of 166 drug-naïve patients with first-episode schizophrenia (fes) and 78 healthy controls (hc) underwent measures for several serum metabolic markers, structural and resting-state functional magnetic resonance imaging (rs-fmri), as well as diffusion tensor imaging (dti). |
2022-05-27 |
2023-08-13 |
Not clear |
| Mengdi Jin, Xiaojing Zhu, Yaoyao Sun, Zhijun Li, Xinwei Li, Lizhe Ai, Yang He, Yane Liu, Ningning Jia, Guoyan Hu, Xingyao Cui, Mengtong Xie, Yuqing Yang, Qiong Y. Identification of Peripheral Blood miRNA Biomarkers in First-Episode Drug-Free Schizophrenia Patients Using Bioinformatics Strategy. Molecular neurobiology. 2022-05-22. PMID:35599275. |
to identify co-expressed mirna modules in schizophrenia patients and verify the possibility of using peripheral blood mirnas as novel biomarkers, high-throughput sequencing was performed on 15 first-episode schizophrenia patients (fes) and 15 healthy controls (ctl). |
2022-05-22 |
2023-08-13 |
Not clear |
| Mengdi Jin, Xiaojing Zhu, Yaoyao Sun, Zhijun Li, Xinwei Li, Lizhe Ai, Yang He, Yane Liu, Ningning Jia, Guoyan Hu, Xingyao Cui, Mengtong Xie, Yuqing Yang, Qiong Y. Identification of Peripheral Blood miRNA Biomarkers in First-Episode Drug-Free Schizophrenia Patients Using Bioinformatics Strategy. Molecular neurobiology. 2022-05-22. PMID:35599275. |
our findings revealed the complex relationship between the mirna co-expression network and fes, providing more verifiable biomarkers for scz early diagnosis and clues for the etiology of schizophrenia. |
2022-05-22 |
2023-08-13 |
Not clear |
| Meng Zhang, Xiang Hong, Fude Yang, Hongzhen Fan, Fengmei Fan, Jiaqi Song, Zhiren Wang, Yunlong Tan, Shuping Tan, L Elliot Hon. Structural brain imaging abnormalities correlate with positive symptom in schizophrenia. Neuroscience letters. 2022-05-20. PMID:35595192. |
this study aimed to investigate associations between positive symptoms and structural brain changes, including alterations in grey matter (gm) volume and cortical thickness, in patients with first-episode schizophrenia (fes). |
2022-05-20 |
2023-08-13 |
Not clear |
| Jingli Chen, Kangkang Xue, Meng Yang, Kefan Wang, Yinhuan Xu, Baohong Wen, Jingliang Cheng, Shaoqiang Han, Yarui We. Altered Coupling of Cerebral Blood Flow and Functional Connectivity Strength in First-Episode Schizophrenia Patients With Auditory Verbal Hallucinations. Frontiers in neuroscience. vol 16. 2022-05-13. PMID:35546878. |
however, the neurovascular coupling alterations specific to first-episode drug-naïve schizophrenia (fes) patients with avhs remain unknown. |
2022-05-13 |
2023-08-13 |
Not clear |
| Du Lei, Xueling Suo, Kun Qin, Walter H L Pinaya, Yuan Ai, Wenbin Li, Weihong Kuang, Su Lui, Graham J Kemp, John A Sweeney, Qiyong Gon. Magnetization transfer imaging alterations and its diagnostic value in antipsychotic-naïve first-episode schizophrenia. Translational psychiatry. vol 12. issue 1. 2022-05-06. PMID:35523792. |
this study aims to identify brain magnetization transfer ratio (mtr) changes in antipsychotic-naïve first-episode schizophrenia (fes), and to correlate mtr findings with clinical symptom severity. |
2022-05-06 |
2023-08-13 |
Not clear |
| Du Lei, Xueling Suo, Kun Qin, Walter H L Pinaya, Yuan Ai, Wenbin Li, Weihong Kuang, Su Lui, Graham J Kemp, John A Sweeney, Qiyong Gon. Magnetization transfer imaging alterations and its diagnostic value in antipsychotic-naïve first-episode schizophrenia. Translational psychiatry. vol 12. issue 1. 2022-05-06. PMID:35523792. |
compared with hcs, individuals with fes exhibited higher mtr values in left thalamus, precuneus, cuneus, and paracentral lobule, that were positively correlated with schizophrenia symptom severity [precuneus (r = 0.34, p = 0.0004), cuneus (r = 0.33, p = 0.0006) and paracentral lobule (r = 0.37, p = 0.001)]. |
2022-05-06 |
2023-08-13 |
Not clear |
| Lei Zhao, Qijing Bo, Zhifang Zhang, Zhenzhu Chen, Yimeng Wang, Douyu Zhang, Tian Li, Ningbo Yang, Yuan Zhou, Chuanyue Wan. Altered dynamic functional connectivity in early psychosis between the salience network and visual network. Neuroscience. 2022-04-10. PMID:35398505. |
in this study, selected core regions of the sn included the left and right anterior insulae (ais) and anterior cingulate cortex (acc), based on independent component analysis of 26 and 20 subjects with first-episode schizophrenia (fes) or at clinical high risk for psychosis (chr), and 37 healthy controls (hc). |
2022-04-10 |
2023-08-13 |
human |
| Yuyan Huang, Weiyan Wang, Gangrui Hei, Ye Yang, Yujun Long, Xiaoyi Wang, Jingmei Xiao, Xijia Xu, Xueqin Song, Shuzhan Gao, Tiannan Shao, Jing Huang, Ying Wang, Jingping Zhao, Renrong W. Altered regional homogeneity and cognitive impairments in first-episode schizophrenia: A resting-state fMRI study. Asian journal of psychiatry. vol 71. 2022-03-18. PMID:35303593. |
by analyzing regional homogeneity (reho) of resting-state functional magnetic resonance imaging, this study aimed to explore the association between brain functional alterations and cognitive deficits in first-episode schizophrenia (fes) with a relatively large sample. |
2022-03-18 |
2023-08-13 |
Not clear |
| Sung Woo Joo, Harin Kim, Young Tak Jo, Soojin Ahn, Young Jae Choi, Woohyeok Choi, Soyeon Park, Jungsun Le. Risk of treatment discontinuation and psychiatric hospitalization associated with early dose reduction of antipsychotic treatment in first-episode schizophrenia: A Nationwide, Health Insurance Data-based Study: Antipsychotic treatment in schizophrenia: Antipsychotic treatment in schizophrenia. Psychiatry and clinical neurosciences. 2022-03-02. PMID:35233892. |
we investigated the impact of early dose reduction of antipsychotic treatment on risk of treatment discontinuation and psychiatric hospitalization in first-episode schizophrenia (fes). |
2022-03-02 |
2023-08-13 |
Not clear |
| Miquel Bioque, Gisela Mezquida, Sílvia Amoretti, Clemente García-Rizo, Jose M López-Ilundain, Covadonga M Diaz-Caneja, Iñaki Zorrilla, Anna Mané, Roberto Rodriguez-Jimenez, Iluminada Corripio, Edith Pomarol-Clotet, Ángela Ibáñez, Judith Usall, Fernando Contreras, Sergi Mas, Javier Vázquez-Bourgon, Manuel J Cuesta, Mara Parellada, Ana González-Pinto, María Hidalgo-Figueroa, Miquel Bernard. Clinical and treatment predictors of relapse during a three-year follow-up of a cohort of first episodes of schizophrenia. Schizophrenia research. vol 243. 2022-03-01. PMID:35231832. |
relapses are frequent in the first years following a first episode of schizophrenia (fes), being associated with a higher risk of developing a chronic psychotic disorder, and poor clinical and functional outcomes. |
2022-03-01 |
2023-08-13 |
human |
| Bing-Jie Huang, Cheng-Cheng Pu, Qi Miao, Ke Ma, Zhang Cheng, Chuan Shi, Xin Y. Neurocognitive trajectories and their clinical implications in first-episode schizophrenia after one year of antipsychotic treatment. Schizophrenia research. vol 241. 2022-02-26. PMID:35217357. |
neurocognitive impairment is a core feature of schizophrenia, and patients with first-episode schizophrenia (fes) are optimal candidates for cognitive remediation, but we do not know enough about the incidence, severity and longitudinal changes in neurocognitive impairment in those with fes. |
2022-02-26 |
2023-08-13 |
Not clear |
| Albert Martínez-Pinteño, Gisela Mezquida, Miquel Bioque, Jose M López-Ilundain, Álvaro Andreu-Bernabeu, Iñaki Zorrilla, Anna Mané, Roberto Rodríguez-Jiménez, Iluminada Corripio, Salvador Sarró, Ángela Ibáñez, Judith Usall, Olga Rivero, Patricia Gassó, Juan Carlos Leza, Manuel J Cuesta, Mara Parellada, Ana González-Pinto, Esther Berrocoso, Sergi Mas, Miguel Bernard. The role of BDNF and NGF plasma levels in first-episode schizophrenia: A longitudinal study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 57. 2022-02-26. PMID:35219096. |
the aims of the present study were to examine the bdnf/ngf plasma levels in a cohort of first-episode schizophrenia (fes) patients in remission as potential biological predictors of relapse; to study the associations between these neurotrophins and the symptomatology severity through different stages after a fes in two independent cohorts. |
2022-02-26 |
2023-08-13 |
Not clear |
| Christoph U Correll, Amber Martin, Charmi Patel, Carmela Benson, Rebecca Goulding, Jennifer Kern-Sliwa, Kruti Joshi, Emma Schiller, Edward Ki. Systematic literature review of schizophrenia clinical practice guidelines on acute and maintenance management with antipsychotics. NPJ schizophrenia. vol 8. issue 1. 2022-02-25. PMID:35210430. |
of 19 cpgs, 17 (89.5%) commented on first-episode schizophrenia (fes), with all recommending antipsychotic monotherapy, but without agreement on preferred antipsychotic. |
2022-02-25 |
2023-08-13 |
Not clear |
| Arsime Demjaha, Silvana Galderisi, Birthe Glenthøj, Celso Arango, Armida Mucci, Andrew Lawrence, Owen O'Daly, Matthew Kempton, Simone Ciufolini, Lone Baandrup, Bjørn H Ebdrup, Roberto Rodriguez-Jimenez, Maria Diaz-Marsa, Covadonga Martinez Díaz-Caneja, Inge Winter van Rossum, Rene Kahn, Paola Dazzan, Philip McGuir. Negative symptoms in First-Episode Schizophrenia related to morphometric alterations in orbitofrontal and superior temporal cortex: the OPTiMiSE study. Psychological medicine. 2022-02-24. PMID:35197142. |
we sought to address these issues by investigating concurrently grey matter volumes (gmv) and cortical thickness (cth) in a large sample of antipsychotic-naïve or minimally treated patients with first-episode schizophrenia (fes). |
2022-02-24 |
2023-08-13 |
Not clear |
| Jing Shi, Hua Guo, Sijia Liu, Wei Xue, Fengmei Fan, Hui Li, Hongzhen Fan, Huimei An, Zhiren Wang, Shuping Tan, Fude Yang, Yunlong Ta. Subcortical Brain Volumes Relate to Neurocognition in First-Episode Schizophrenia, Bipolar Disorder, Major Depression Disorder, and Healthy Controls. Frontiers in psychiatry. vol 12. 2022-02-11. PMID:35145436. |
to explore differences and similarities in relationships between subcortical structure volumes and neurocognition among the four subject groups, including first-episode schizophrenia (fes), bipolar disorder (bd), major depression disorder (mdd), and healthy controls (hcs). |
2022-02-11 |
2023-08-13 |
human |
| Lorenzo Pelizza, Emanuela Leuci, Davide Maestri, Emanuela Quattrone, Silvia Azzali, Giuseppina Paulillo, Pietro Pellegrin. Negative symptoms in first episode schizophrenia: treatment response across the 2-year follow-up of the "Parma Early Psychosis" program. European archives of psychiatry and clinical neuroscience. 2022-01-28. PMID:35088121. |
thus, the aims of this study were (1) to longitudinally monitor the ns stability in young individuals with first episode schizophrenia (fes) across a 2-year follow-up period, and (2) to investigate any significant association of ns with functioning, other aspects of fes psychopathology and the specific treatment component effects on ns of an "early intervention in psychosis" (eip) program during the 2 years of follow-up. |
2022-01-28 |
2023-08-13 |
human |
| Sherry Kit Wa Chan, Janet Hsiao, Audrey On Yui Wong, Yingqi Liao, Yinam Suen, Eric Wai Ching Yan, Lap-Tak Poon, Man Wah Siu, Christy Lai Ming Hui, Wing Chung Chang, Edwin Ho Ming Lee, Eric Yu Hai Che. Explicit and implicit mentalization of patients with first-episode schizophrenia: a study of self-referential gaze perception with eye movement analysis using hidden Markov models. European archives of psychiatry and clinical neuroscience. 2022-01-26. PMID:35079856. |
in this case-control study, 30 patients with first-episode schizophrenia (fes) and 30 matched healthy controls were assigned gaze perception tasks with variable stimulus presentation times (300 ms and no time limit) to determine the presence of self-referential gaze perception (srgp) bias. |
2022-01-26 |
2023-08-13 |
Not clear |