| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lorenzo Pelizza, Emanuela Leuci, Davide Maestri, Emanuela Quattrone, Silvia Azzali, Giuseppina Paulillo, Pietro Pellegrin. Negative symptoms in first episode schizophrenia: treatment response across the 2-year follow-up of the "Parma Early Psychosis" program. European archives of psychiatry and clinical neuroscience. 2022-01-28. PMID:35088121. |
thus, the aims of this study were (1) to longitudinally monitor the ns stability in young individuals with first episode schizophrenia (fes) across a 2-year follow-up period, and (2) to investigate any significant association of ns with functioning, other aspects of fes psychopathology and the specific treatment component effects on ns of an "early intervention in psychosis" (eip) program during the 2 years of follow-up. |
2022-01-28 |
2023-08-13 |
human |
| Sherry Kit Wa Chan, Janet Hsiao, Audrey On Yui Wong, Yingqi Liao, Yinam Suen, Eric Wai Ching Yan, Lap-Tak Poon, Man Wah Siu, Christy Lai Ming Hui, Wing Chung Chang, Edwin Ho Ming Lee, Eric Yu Hai Che. Explicit and implicit mentalization of patients with first-episode schizophrenia: a study of self-referential gaze perception with eye movement analysis using hidden Markov models. European archives of psychiatry and clinical neuroscience. 2022-01-26. PMID:35079856. |
in this case-control study, 30 patients with first-episode schizophrenia (fes) and 30 matched healthy controls were assigned gaze perception tasks with variable stimulus presentation times (300 ms and no time limit) to determine the presence of self-referential gaze perception (srgp) bias. |
2022-01-26 |
2023-08-13 |
Not clear |
| Lorenzo Pelizza, Emanuela Leuci, Davide Maestri, Emanuela Quattrone, Silvia Azzali, Giuseppina Paulillo, Pietro Pellegrin. Longitudinal persistence of negative symptoms in young individuals with first episode schizophrenia: a 24-month multi-modal program follow-up. Nordic journal of psychiatry. 2021-12-22. PMID:34936855. |
longitudinal studies on beneficial effects of psychosocial treatments for pns in first episode schizophrenia (fes) are still relatively scarce. |
2021-12-22 |
2023-08-13 |
Not clear |
| Jiewei Wu, Guiwen Lyu, Kai Wang, Xiaoying Tan. A Hybrid Learning Pipeline for Automated Diagnosis of First-Episode Schizophrenia Utilizing T1-weighted Images. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2021. 2021-12-11. PMID:34891821. |
in this work, we proposed and validated a hybrid learning pipeline for automated diagnosis of first-episode schizophrenia (fes) utilizing t1-weighted images. |
2021-12-11 |
2023-08-13 |
Not clear |
| Michael Maes, Kitiporn Plaimas, Apichat Suratanee, Cristiano Noto, Buranee Kanchanatawa. First Episode Psychosis and Schizophrenia Are Systemic Neuro-Immune Disorders Triggered by a Biotic Stimulus in Individuals with Reduced Immune Regulation and Neuroprotection. Cells. vol 10. issue 11. 2021-12-08. PMID:34831151. |
studies performed on antipsychotic-naïve first episode psychosis (an-fep) and schizophrenia (fes) patients are important as they may disclose the pathogenesis of fes. |
2021-12-08 |
2023-08-13 |
Not clear |
| Dung Hoang, Yanxun Xu, Olivia Lutz, Deepthi Bannai, Victor Zeng, Jeffrey R Bishop, Matcheri Keshavan, Paulo Lizan. Inflammatory Subtypes in Antipsychotic-Naïve First-Episode Schizophrenia are Associated with Altered Brain Morphology and Topological Organization. Brain, behavior, and immunity. 2021-12-07. PMID:34875344. |
it is unclear if inflammatory subtypes exist earlier in the disease course, thus, we aim to identify inflammatory subtypes in antipsychotic naïve first-episode schizophrenia (fes). |
2021-12-07 |
2023-08-13 |
Not clear |
| Ryan Sai-Ting Chu, Chung-Mun Ng, Kwun-Nam Chan, Kit-Wa Chan, Ho-Ming Lee, Lai-Ming Hui, Eric Chen, Wing-Chung Chan. Aberrant Learned Irrelevance in Patients with First-Episode Schizophrenia-Spectrum Disorder. Brain sciences. vol 11. issue 11. 2021-11-29. PMID:34827368. |
there is a paucity of studies on lirr in first-episode schizophrenia-spectrum disorder (i.e., schizophrenia and schizophreniform disorder; fes), which were limited by small sample size and have produced mixed results. |
2021-11-29 |
2023-08-13 |
Not clear |
| Ryan Sai-Ting Chu, Chung-Mun Ng, Kwun-Nam Chan, Kit-Wa Chan, Ho-Ming Lee, Lai-Ming Hui, Eric Chen, Wing-Chung Chan. Aberrant Learned Irrelevance in Patients with First-Episode Schizophrenia-Spectrum Disorder. Brain sciences. vol 11. issue 11. 2021-11-29. PMID:34827368. |
the current study examined a lirr effect and its relationship with positive symptom severity in 40 briefly-medicated fes patients and 42 demographically-matched healthy controls using a well-validated computerized lirr paradigm which has been applied in chronic schizophrenia sample. |
2021-11-29 |
2023-08-13 |
Not clear |
| Xiao Zhong, Qin Ao, Fei Xin. Serum Levels of HCY, MIF, and hs-CRP Correlate with Glycolipid Metabolism in Adults with Never-Medicated First-Episode Schizophrenia. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-11-24. PMID:34812265. |
the study is designed to compare the glycolipid metabolism in patients with first-episode schizophrenia (fes) with sex- and age-matched healthy controls to investigate changes in serum levels of homocysteine (hcy), macrophage migration inhibitory factor (mif), and high-sensitive c-reactive protein (hs-crp) and their relationships with the glycolipid metabolism in patients with fes. |
2021-11-24 |
2023-08-13 |
Not clear |
| Sherry Kit Wa Chan, Hei Yan Veronica Chan, William G Honer, Tarun Bastiampillai, Yi Nam Suen, Wai Song Yeung, Ming Lam, Wing King Lee, Roger Man King Ng, Christy Lai Ming Hui, Wing Chung Chang, Edwin Ho Ming Lee, Eric Yu Hai Che. Predictors of Treatment-Resistant and Clozapine-Resistant Schizophrenia: A 12-Year Follow-up Study of First-Episode Schizophrenia-Spectrum Disorders. Schizophrenia bulletin. vol 47. issue 2. 2021-11-22. PMID:33043960. |
studies on the long-term development and early predictors of treatment-resistant schizophrenia (trs) and clozapine-resistant trs (cr-trs) in patients with first-episode schizophrenia-spectrum disorders (fes) are limited and have not considered the impact of early intervention services (eis). |
2021-11-22 |
2023-08-13 |
Not clear |
| Qijing Bo, Zhen Mao, Qing Tian, Ningbo Yang, Xianbin Li, Fang Dong, Fuchun Zhou, Liang Li, Chuanyue Wan. Impaired Sensorimotor Gating Using the Acoustic Prepulse Inhibition Paradigm in Individuals at a Clinical High Risk for Psychosis. Schizophrenia bulletin. vol 47. issue 1. 2021-11-19. PMID:32743658. |
the current study investigated an improved pssppi condition in chr individuals compared with patients with first-episode schizophrenia (fes) and healthy controls (hc) and evaluated the accuracy of ppi in predicting chr from hc. |
2021-11-19 |
2023-08-13 |
human |
| Wei Wei, Yamin Zhang, Yinfei Li, Yajin Meng, Mingli Li, Qiang Wang, Wei Deng, Xiaohong Ma, Lena Palaniyappan, Nanyin Zhang, Tao L. Depth-dependent abnormal cortical myelination in first-episode treatment-naïve schizophrenia. Human brain mapping. vol 41. issue 10. 2021-11-08. PMID:32239735. |
here for the first time, we characterized intracortical myelination across the entire cortical surface in first-episode treatment-naïve patients with schizophrenia (fes) using t1w/t2w ratio of structural mri, fes patients exhibited significantly higher myelin content in the left inferior parietal lobe, supramarginal gyrus, and superior temporal gyrus in the superficial layer, as well as left ipl in the middle layer, but significantly lower myelin content in the left middle insula and posterior cingulate gyrus. |
2021-11-08 |
2023-08-13 |
human |
| Jingnan Du, Lena Palaniyappan, Zhaowen Liu, Wei Cheng, Weikang Gong, Mengmeng Zhu, Jijun Wang, Jie Zhang, Jianfeng Fen. The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia. NPJ schizophrenia. vol 7. issue 1. 2021-11-06. PMID:33658499. |
this study used two independent schizophrenia dataset consisting of 138 and 53 drug-naïve first-episode schizophrenia (fes) patients, and 112 and 56 healthy controls, respectively. |
2021-11-06 |
2023-08-13 |
Not clear |
| Gaoping Cui, Ying Qing, Minghui Li, Liya Sun, Juan Zhang, Lei Feng, Jing Li, Tianlu Chen, Jijun Wang, Chunling Wa. Salivary Metabolomics Reveals that Metabolic Alterations Precede the Onset of Schizophrenia. Journal of proteome research. vol 20. issue 11. 2021-11-05. PMID:34618462. |
therefore, we conducted salivary metabolomics analysis in 83 first-episode schizophrenia (fes) patients, 42 chr individuals, and 78 healthy controls with ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. |
2021-11-05 |
2023-08-13 |
Not clear |
| Gaoping Cui, Ying Qing, Minghui Li, Liya Sun, Juan Zhang, Lei Feng, Jing Li, Tianlu Chen, Jijun Wang, Chunling Wa. Salivary Metabolomics Reveals that Metabolic Alterations Precede the Onset of Schizophrenia. Journal of proteome research. vol 20. issue 11. 2021-11-05. PMID:34618462. |
we found downregulated aromatic amino acid metabolism, disturbed glutamine and nucleotide metabolism, and upregulated tricarboxylic acid cycle in fes patients, which existed even in the chr stage and became more intense with the onset of the schizophrenia. |
2021-11-05 |
2023-08-13 |
Not clear |
| Ying Qing, Lihua Xu, Gaoping Cui, Liya Sun, Xiaowen Hu, Xuhan Yang, Jie Jiang, Juan Zhang, Tianhong Zhang, Tao Wang, Lin He, Jijun Wang, Chunling Wa. Salivary microbiome profiling reveals a dysbiotic schizophrenia-associated microbiota. NPJ schizophrenia. vol 7. issue 1. 2021-11-01. PMID:34711862. |
to address this, we performed 16s rrna gene sequencing to investigate the salivary microbiome in 85 patients with drug-naïve first-episode schizophrenia (fes), 43 individuals at chr, and 80 healthy controls (hcs). |
2021-11-01 |
2023-08-13 |
human |
| Yuan Xiao, Wei Liao, Zhiliang Long, Bo Tao, Qiannan Zhao, Chunyan Luo, Carol A Tamminga, Matcheri S Keshavan, Godfrey D Pearlson, Brett A Clementz, Elliot S Gershon, Elena I Ivleva, Sarah K Keedy, Bharat B Biswal, Andrea Mechelli, Rebekka Lencer, John A Sweeney, Su Lui, Qiyong Gon. Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alterations. Schizophrenia bulletin. 2021-09-11. PMID:34508358. |
cross-sectional structural mr images of 163 never-treated first-episode schizophrenia patients (fes) and 133 chronically ill patients with midcourse schizophrenia from the bipolar and schizophrenia network for intermediate phenotypes (b-snip) consortium and a total of 403 healthy controls were recruited. |
2021-09-11 |
2023-08-13 |
human |
| Wenjun Su, Tianyuan Zhu, Lihua Xu, Yanyan Wei, Botao Zeng, Tianhong Zhang, Huiru Cui, Junjie Wang, Yuping Jia, Jinhong Wang, Donald C Goff, Yingying Tang, Jijun Wan. Effect of DAOA genetic variation on white matter alteration in corpus callosum in patients with first-episode schizophrenia. Brain imaging and behavior. vol 15. issue 4. 2021-09-06. PMID:32748316. |
we aimed to investigate whether the variation of daoa rs2391191 is associated with alterations in white matter integrity of first-episode schizophrenia (fes) patients; and whether it influences the association between white matter integrity, cognitive function and clinical symptoms of schizophrenia. |
2021-09-06 |
2023-08-13 |
Not clear |
| Qi Yu, Wujin Weng, Hongfei Zhou, Yamei Tang, Shan Ding, Kai Huang, Yong Li. Elevated Platelet Parameter in First-Episode Schizophrenia Patients: A Cross-Sectional Study. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 40. issue 11. 2021-09-02. PMID:33121305. |
the aim of this study was to evaluate changes of platelet count (plt), mean platelet volume (mpv), platelet-large cell ratio (p-lcr), platelet distribution width (pdw), and plateletcrit (pct) in patients with first-episode schizophrenia (fes). |
2021-09-02 |
2023-08-13 |
Not clear |
| Kara Dempster, Annie Li, Priyadharshini Sabesan, Ross Norman, Lena Palaniyappa. Treatment Resistance: A Time-Based Approach for Early Identification in First Episode Psychosis. Journal of personalized medicine. vol 11. issue 8. 2021-08-31. PMID:34442355. |
the treatment response and resistance in psychosis working group defines <20% improvement as an indicator of tr, though its utility in first episode schizophrenia (fes) remains unknown. |
2021-08-31 |
2023-08-13 |
human |