| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zafiris J Daskalakis, Paul B Fitzgerald, Bruce K Christense. The role of cortical inhibition in the pathophysiology and treatment of schizophrenia. Brain research reviews. vol 56. issue 2. 2008-02-14. PMID:17980435. |
dysfunctional cortical inhibition (ci) has been suggested as a mechanism through which symptoms of schizophrenia (scz) are mediated. |
2008-02-14 |
2023-08-12 |
Not clear |
| Vural Ozdemir, M Mazen Jamal, Klara Osapay, Martin R Jadus, Zsuzsanna Sandor, Mehrtash Hashemzadeh, Sandor Szab. Cosegregation of gastrointestinal ulcers and schizophrenia in a large national inpatient discharge database: revisiting the "brain-gut axis" hypothesis in ulcer pathogenesis. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 55. issue 6. 2008-01-10. PMID:17963681. |
a significant association was observed between schizophrenia and diminished risk for duodenal (odds ratio [or] 0.55; 95% confidence interval [ci] 0.45-0.67) and gastric (or 0.54; 95% ci 0.46-0.63) (p < .01) ulcers but not for gastrojejunal ulcers (or 0.44; 95% ci 0.16-1.20) (p = .11). |
2008-01-10 |
2023-08-12 |
Not clear |
| Anna C Svensson, Paul Lichtenstein, Sven Sandin, Christina M Hultma. Fertility of first-degree relatives of patients with schizophrenia: a three generation perspective. Schizophrenia research. vol 91. issue 1-3. 2007-06-12. PMID:17275261. |
the fertility among males with schizophrenia was decreased by over 70% (fertility ratio(patients/population)=0.29, 95% ci 0.25-0.35), whereas female patients had less than half as many offspring as the general female population (fertility ratio(patients/population)=0.48, 95% ci 0.42-0.55). |
2007-06-12 |
2023-08-12 |
human |
| Mary C Perrin, Mark G Opler, Susan Harlap, Jill Harkavy-Friedman, Karine Kleinhaus, Daniella Nahon, Shmuel Fennig, Ezra S Susser, Dolores Malaspin. Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findings. Schizophrenia research. vol 90. issue 1-3. 2007-05-30. PMID:17113267. |
we observed an increased incidence of schizophrenia in offspring of parents who were dry cleaners (rr=3.4, 95% ci, 1.3-9.2, p=0.01). |
2007-05-30 |
2023-08-12 |
Not clear |
| Mikkel Arendt, Raben Rosenberg, Leslie Foldager, Gurli Perto, Povl Munk-Jørgense. Psychopathology among cannabis-dependent treatment seekers and association with later substance abuse treatment. Journal of substance abuse treatment. vol 32. issue 2. 2007-05-02. PMID:17306720. |
the proportion of treatment for all psychiatric disorders was much higher among cases than among controls: schizophrenia (odds ratio [or] = 7.9; 95% confidence interval [95% ci] = 6.1-10.2), bipolar disorders (or = 4.9; 95% ci = 2.8-8.5), other affective disorders (or = 7.6; 95% ci = 6.1-9.5), and personality disorders (or = 17.3; 95% ci = 14.5-20.5). |
2007-05-02 |
2023-08-12 |
human |
| Gerald Stöber, Julia Sprandel, Burkhard Jabs, Bruno Pfuhlmann, Kerstin Möller-Ehrlich, Michael Knap. Family-based study of markers at the 5'-flanking region of the human dopamine transporter gene reveals potential association with schizophrenic psychoses. European archives of psychiatry and clinical neuroscience. vol 256. issue 7. 2007-02-26. PMID:16783497. |
distinct five-locus-genotypes accumulated in schizophrenia compared to parental controls at p-value 0.0038 with odds-ratio of 2.02 (95% ci 0.99-4.14). |
2007-02-26 |
2023-08-12 |
human |
| Isabel Martínez-Gras, Janet Hoenicka, Guillermo Ponce, Roberto Rodríguez-Jiménez, Miguel Angel Jiménez-Arriero, Elena Pérez-Hernandez, Israel Ampuero, Jose Antonio Ramos-Atance, Tomas Palomo, Gabriel Rubi. (AAT)n repeat in the cannabinoid receptor gene, CNR1: association with schizophrenia in a Spanish population. European archives of psychiatry and clinical neuroscience. vol 256. issue 7. 2007-02-26. PMID:16788767. |
no differences have been found with respect to substance abuse.thus, the allele 4 represents, in our sample, a protective factor against schizophrenia (odds ratio 0.468, 95% confidence interval (ci) 0.27-0.79). |
2007-02-26 |
2023-08-12 |
Not clear |
| Isabel Martínez-Gras, Janet Hoenicka, Guillermo Ponce, Roberto Rodríguez-Jiménez, Miguel Angel Jiménez-Arriero, Elena Pérez-Hernandez, Israel Ampuero, Jose Antonio Ramos-Atance, Tomas Palomo, Gabriel Rubi. (AAT)n repeat in the cannabinoid receptor gene, CNR1: association with schizophrenia in a Spanish population. European archives of psychiatry and clinical neuroscience. vol 256. issue 7. 2007-02-26. PMID:16788767. |
the population attributable genetic risk for the allele 4 absence is 30% (95% ci = 17-41%) and the attributable risk for the allele 4 absence in those with schizophrenia is 53% (95% ci = 20-73%). |
2007-02-26 |
2023-08-12 |
Not clear |
| Simon Gilbody, Sarah Lewis, Tracy Lightfoo. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. American journal of epidemiology. vol 165. issue 1. 2007-02-15. PMID:17074966. |
for schizophrenia and mthfr c677t, the fixed-effects odds ratio for tt versus cc was 1.44 (95% ci: 1.21, 1.70), with low heterogeneity (i(2) = 42%)--based on 2,762 cases and 3,363 controls. |
2007-02-15 |
2023-08-12 |
Not clear |
| Sheila Passos Gregorio, Wagner F Gattaz, Hildeberto Tavares, Christian Kieling, Sally Timm, August G Wang, Henrik Berg Rasmussen, Thomas Werge, Emmanuel Dias-Net. Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects. Schizophrenia research. vol 88. issue 1-3. 2007-02-06. PMID:16899352. |
when the brazilian and danish cohorts were merged, a total of 1084 subjects, we found the allele 18 cag of numbl (p=0.003, x2=8.88, or=1.30, 95% ci 1.09-1.56) as well as the 18/18 cag genotype (p=0.002, x2=9.46, or=1.46, 95% ci 1.15-1.87) to be associated with schizophrenia. |
2007-02-06 |
2023-08-12 |
human |
| Brian H Shirts, Joel Wood, Robert H Yolken, Vishwajit L Nimgaonka. Association study of IL10, IL1beta, and IL1RN and schizophrenia using tag SNPs from a comprehensive database: suggestive association with rs16944 at IL1beta. Schizophrenia research. vol 88. issue 1-3. 2007-02-06. PMID:16905295. |
however, meta-analysis of our data combined with previously published association studies of rs16944 (il1beta -511) suggests that the c allele confers modest risk for schizophrenia among individuals reporting caucasian ancestry, but not asians (caucasians, n=819 cases, 1292 controls; p=0.0013, or=1.24, 95% ci 1.09, 1.41). |
2007-02-06 |
2023-08-12 |
Not clear |
| Janice A Husted, Celia M T Greenwood, Anne S Basset. Heritability of schizophrenia and major affective disorder as a function of age, in the presence of strong cohort effects. European archives of psychiatry and clinical neuroscience. vol 256. issue 4. 2006-12-15. PMID:16331352. |
a sibling's risk of hospitalization for the same illness significantly increased for each 10-year decrease in age at onset of the proband both for schizophrenia (hazard ratio = 1.21, 95 % confidence interval: 1.06, 1.39), and for affective disorder (hazard ratio = 1.29,95 % ci: 1.14, 1.45). |
2006-12-15 |
2023-08-12 |
Not clear |
| B S Pickard, M P Malloy, A Christoforou, P A Thomson, K L Evans, S W Morris, M Hampson, D J Porteous, D H R Blackwood, W J Mui. Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder. Molecular psychiatry. vol 11. issue 9. 2006-11-27. PMID:16819533. |
this identified two discrete regions of disease risk within the grik4 locus: three single single nucleotide polymorphism (snp) markers with a corresponding underlying haplotype associated with susceptibility to schizophrenia (p=0.0005, odds ratio (or) of 1.453, 95% ci 1.182-1.787) and two single snp markers and a haplotype associated with a protective effect against bipolar disorder (p=0.0002, or of 0.624, 95% ci 0.485-0.802). |
2006-11-27 |
2023-08-12 |
Not clear |
| Kari Hänninen, Heikki Katila, Olli Kampman, Sami Anttila, Ari Illi, Riikka Rontu, Kari M Mattila, Jarmo Hietala, Mikko Hurme, Esa Leinonen, Terho Lehtimäk. Association between the C957T polymorphism of the dopamine D2 receptor gene and schizophrenia. Neuroscience letters. vol 407. issue 3. 2006-11-27. PMID:16973280. |
a greater proportion of patients with schizophrenia than healthy controls were c-allele carriers (odds ratio 1.5, 95% confidence interval (ci) 1.0-2.3, p=0.05). |
2006-11-27 |
2023-08-12 |
Not clear |
| Adalberto Campo-Arias, Luis A Díaz-Martínez, Germán E Rueda-Jaimes, Mauricio Rueda-Sánchez, Daniel Farelo-Palacín, Francisco J Diaz, Jose de Leo. Smoking is associated with schizophrenia, but not with mood disorders, within a population with low smoking rates: a matched case-control study in Bucaramanga, Colombia. Schizophrenia research. vol 83. issue 2-3. 2006-09-19. PMID:16497482. |
prevalences of current smoking were 26% for schizophrenia patients and 10% for their matched controls (adjusted mantel-haenszel or=3.1, 95% ci, 1.4-6.8), and 7% for patients with mood disorders and 12% for their matched controls (adjusted mantel-haenszel or=0.62; ci, 0.28-1.4). |
2006-09-19 |
2023-08-12 |
Not clear |
| Sepideh N Bajestan, Amir H Sabouri, Masayuki Nakamura, Hiroshi Takashima, Mohammad R Keikhaee, Fatemeh Behdani, Mohammad R Fayyazi, Mohammad R Sargolzaee, Mahboobeh N Bajestan, Zahra Sabouri, Esmaeil Khayami, Sima Haghighi, Susan B Hashemi, Nobutaka Eiraku, Hamid Tufani, Hossein Najmabadi, Kimiyoshi Arimura, Akira Sano, Mitsuhiro Osam. Association of AKT1 haplotype with the risk of schizophrenia in Iranian population. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 141B. issue 4. 2006-08-16. PMID:16583435. |
in stratified analysis by schizophrenia subtypes, the frequency of the same haplotype was significantly higher in disorganized subtype (n = 78, frequency of haplotype=0.081) when compared with normal controls (p = 0.04 after bonferroni correction, or = 2.59, ci = 1.3-5.2). |
2006-08-16 |
2023-08-12 |
Not clear |
| J W Muntjewerff, R S Kahn, H J Blom, M den Heije. Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis. Molecular psychiatry. vol 11. issue 2. 2006-06-06. PMID:16172608. |
a 5 micromol/l higher homocysteine level was associated with a 70% (95% confidence interval, ci: 27-129) higher risk of schizophrenia. |
2006-06-06 |
2023-08-12 |
human |
| J W Muntjewerff, R S Kahn, H J Blom, M den Heije. Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis. Molecular psychiatry. vol 11. issue 2. 2006-06-06. PMID:16172608. |
the tt genotype was associated with a 36% (95% ci: 7-72) higher risk of schizophrenia compared to the cc genotype. |
2006-06-06 |
2023-08-12 |
human |
| Piercarlo Minoretti, Pierluigi Politi, Enrico Coen, Clara Di Vito, Marco Bertona, Marika Bianchi, Enzo Emanuel. The T393C polymorphism of the GNAS1 gene is associated with deficit schizophrenia in an Italian population sample. Neuroscience letters. vol 397. issue 1-2. 2006-05-25. PMID:16406317. |
this association with deficit schizophrenia persisted even after allowance for potential confounders [adjusted odds ratio (or) for deficit schizophrenia: 2.06 (95% confidence interval (ci): 1.21-3.47), p=0.007]. |
2006-05-25 |
2023-08-12 |
mouse |
| Anne S Bassett, Eva W C Chow, Janice Husted, Rosanna Weksberg, Oana Caluseriu, Gary D Webb, Michael A Gatzouli. Clinical features of 78 adults with 22q11 Deletion Syndrome. American journal of medical genetics. Part A. vol 138. issue 4. 2006-03-28. PMID:16208694. |
adjusting for ascertainment, 25.8% (95% ci, 9.5-42.1%) of patients had cardiac anomalies and 22.6% (95% ci, 7.0-38.2%) had schizophrenia. |
2006-03-28 |
2023-08-12 |
human |