| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kassandra Lanchais, Frederic Capel, Anne Tournadr. Could Omega 3 Fatty Acids Preserve Muscle Health in Rheumatoid Arthritis? Nutrients. vol 12. issue 1. 2020-11-16. PMID:31952247. |
moreover, the accumulation of toxic lipid mediators (i.e., lipotoxicity) in skeletal muscles can induce mitochondrial dysfunctions and insulin resistance, which are both crucial determinants of cvd and sarcopenia. |
2020-11-16 |
2023-08-13 |
human |
| Youn I Choi, Dong Kyun Park, Jun-Won Chung, Kyoung Oh Kim, Kwang An Kwon, Yoon Jae Ki. Circadian rhythm disruption is associated with an increased risk of sarcopenia: a nationwide population-based study in Korea. Scientific reports. vol 9. issue 1. 2020-11-02. PMID:31427694. |
compared to the group that had never experienced shift work, the odds ratio (or) for sarcopenia with a 95% confidence interval (95% ci) for the shift work group was 1.7 (1.5-1.9); the association remained even after adjusting for confounding variables, including age, sex, total fat mass, insulin resistance profile, smoking, alcohol intake, diet, and physical activity. |
2020-11-02 |
2023-08-13 |
Not clear |
| Kazuhito Oba, Joji Ishikawa, Yoshiaki Tamura, Yasunori Fujita, Masafumi Ito, Ai Iizuka, Yoshinori Fujiwara, Remi Kodera, Ayumi Toba, Kenji Toyoshima, Yuko Chiba, Seijiro Mori, Masashi Tanaka, Hideki Ito, Kazumasa Harada, Atsushi Arak. Serum growth differentiation factor 15 level is associated with muscle strength and lower extremity function in older patients with cardiometabolic disease. Geriatrics & gerontology international. vol 20. issue 10. 2020-10-19. PMID:32886834. |
growth differentiation factor 15 (gdf15) is associated with mitochondrial dysfunction, inflammation, insulin resistance and oxidative stress, which may play crucial roles for the development of sarcopenia. |
2020-10-19 |
2023-08-13 |
Not clear |
| Kayleigh M Beaudry, Michaela C Devrie. Nutritional Strategies to Combat Type 2 Diabetes in Aging Adults: The Importance of Protein. Frontiers in nutrition. vol 6. 2020-10-01. PMID:31555655. |
the purpose of the current review is to discuss the role of protein to attenuate declines in muscle mass and insulin sensitivity to prevent t2d and sarcopenia in aging adults. |
2020-10-01 |
2023-08-13 |
Not clear |
| Hiroyuki Umegaki, Taeko Makino, Kazuki Uemura, Hiroyuki Shimada, Takahiro Hayashi, Xian Wu Cheng, Masafumi Kuzuy. The Associations among Insulin Resistance, Hyperglycemia, Physical Performance, Diabetes Mellitus, and Cognitive Function in Relatively Healthy Older Adults with Subtle Cognitive Dysfunction. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:28386227. |
insulin resistance (ir), diabetes mellitus (dm), sarcopenia, and cognitive dysfunction are thought to be mutually associated. |
2020-09-30 |
2023-08-13 |
human |
| Richie D Barclay, Nicholas A Burd, Christopher Tyler, Neale A Tillin, Richard W Mackenzi. The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle. Frontiers in nutrition. vol 6. 2020-09-30. PMID:31552262. |
furthermore, this review will present the hypothesis that inositol hexakisphosphate kinase 1 (ip6k1) may be implicated in igf-1 signaling and thus sarcopenia, based on recent evidence that igf-1 and insulin share some intracellular bound signaling events and that ip6k1 has been implicated in skeletal muscle insulin resistance. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kayoung Le. Association of osteosarcopenic obesity and its components: osteoporosis, sarcopenia and obesity with insulin resistance. Journal of bone and mineral metabolism. vol 38. issue 5. 2020-09-30. PMID:32335754. |
association of osteosarcopenic obesity and its components: osteoporosis, sarcopenia and obesity with insulin resistance. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kayoung Le. Association of osteosarcopenic obesity and its components: osteoporosis, sarcopenia and obesity with insulin resistance. Journal of bone and mineral metabolism. vol 38. issue 5. 2020-09-30. PMID:32335754. |
to evaluate the differences in the associations of combinations of co-existent osteopenia, obesity, and/or sarcopenia with insulin resistance (ir) according to different criteria of obesity. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jian Shou, Pei-Jie Chen, Wei-Hua Xia. Mechanism of increased risk of insulin resistance in aging skeletal muscle. Diabetology & metabolic syndrome. vol 12. 2020-09-28. PMID:32082422. |
during skeletal muscle aging, mitochondrial dysfunction, intramyocellular lipid accumulation, increased inflammation, oxidative stress, modified activity of insulin sensitivity regulatory enzymes, endoplasmic reticulum stress, decreased autophagy, sarcopenia and over-activated renin-angiotensin system may occur. |
2020-09-28 |
2023-08-13 |
Not clear |
| Syed Shahid Habib, Shaea Alkahtani, Maha Alhussain, Osama Aljuhan. Sarcopenia Coexisting with High Adiposity Exacerbates Insulin Resistance and Dyslipidemia in Saudi Adult Men. Diabetes, metabolic syndrome and obesity : targets and therapy. vol 13. 2020-09-28. PMID:32922058. |
sarcopenia coexisting with high adiposity exacerbates insulin resistance and dyslipidemia in saudi adult men. |
2020-09-28 |
2023-08-13 |
Not clear |
| Shariff-Ghazali Sazlina, Ping Yein Lee, Yoke Mun Chan, Mohamad Shariff A Hamid, Ngiap Chuan Ta. The prevalence and factors associated with sarcopenia among community living elderly with type 2 diabetes mellitus in primary care clinics in Malaysia. PloS one. vol 15. issue 5. 2020-08-06. PMID:32433712. |
those aged ≥70 years (β = 0.73;or = 2.07; 95%ci = 1.24, 3.48; p = 0.006), men (β = 0.61; or = 1.84; 95%ci = 1.12, 3.02; p = 0.017), with ≥10 years duration of diabetes (β = 0.62; or = 1.85; 95%ci = 1.11, 3.09; p = 0.018), not using insulin sensitizers (β = -1.44; or = 0.24; 95%ci = 0.08, 0.71; p = 0.010), using less than 5 medications (β = 0.68; or = 1.98; 95%ci = 1.17, 3.36; p = 0.011), low body mass index (bmi) (β = -2.43; or = 0.09; 95%ci = 0.05, 0.17; p<0.001), and engaging in low (β = 0.77; or = 2.15; 95%ci = 1.07, 4.35; p = 0.032) and moderate physical activities (β = 0.80; or = 2.23; 95%ci = 1.07, 4.66; p = 0.033) were associated with sarcopenia. |
2020-08-06 |
2023-08-13 |
Not clear |
| Yih-Hsin Chang, Jen-Ning Tsai, Tzu-Lin Chen, Kuo-Ting Ho, Hsin-Yi Cheng, Chiao-Wan Hsiao, Ming-Yuh Shia. Interleukin-4 Promotes Myogenesis and Boosts Myocyte Insulin Efficacy. Mediators of inflammation. vol 2019. 2020-06-01. PMID:31814802. |
il-4 has dual potential to act as an adjuvant therapeutic target for sarcopenia to preserve muscle mass and insulin resistance to improve insulin sensitivity, which implicates the regulation of immune system to the muscle differentiation and exercise performance. |
2020-06-01 |
2023-08-13 |
mouse |
| Leslie A Consitt, Courtney Dudley, Gunjan Saxen. Impact of Endurance and Resistance Training on Skeletal Muscle Glucose Metabolism in Older Adults. Nutrients. vol 11. issue 11. 2020-04-27. PMID:31684154. |
some of these changes include sarcopenia, impaired insulin signaling, and imbalances in glucose utilization. |
2020-04-27 |
2023-08-13 |
Not clear |
| Paola Antonia Corsetto, Gigliola Montorfano, Catherine Klersy, Luca Massimino, Vittoria Infantino, Giancarlo Iannello, Milena Anna Faliva, Henry Lukaski, Simone Perna, Tariq A Alalwan, Angela Maria Rizzo, Mariangela Rondanell. Fatty Acid Profile and Antioxidant Status Fingerprint in Sarcopenic Elderly Patients: Role of Diet and Exercise. Nutrients. vol 11. issue 11. 2020-04-08. PMID:31653011. |
plasma fatty acids (fas) and oxidant status contribute to the etiology of sarcopenia in the elderly concurring to age-related muscle loss and elderly frailty through several mechanisms including changes in fa composition within the sarcolemma, promotion of chronic low-grade inflammation, and insulin resistance. |
2020-04-08 |
2023-08-13 |
human |
| Kathryn J Jacob, Stéphanie Chevalier, Marie Lamarche, José A Morai. Leucine Supplementation Does Not Alter Insulin Sensitivity in Prefrail and Frail Older Women following a Resistance Training Protocol. The Journal of nutrition. vol 149. issue 6. 2020-04-06. PMID:31149709. |
leucine acutely increases muscle protein synthesis, and resistance training (rt) is the strongest stimuli to counteract sarcopenia and was recently shown to improve insulin sensitivity (is) in frail older women. |
2020-04-06 |
2023-08-13 |
Not clear |
| Anne Tournadre, Gaelle Vial, Frédéric Capel, Martin Soubrier, Yves Boiri. Sarcopenia. Joint bone spine. vol 86. issue 3. 2020-02-20. PMID:30098424. |
sarcopenia results from complex and interdependent pathophysiological mechanisms that include aging, physical inactivity, neuromuscular compromise, resistance to postprandial anabolism, insulin resistance, lipotoxicity, endocrine factors, oxidative stress, mitochondrial dysfunction, and inflammation. |
2020-02-20 |
2023-08-13 |
Not clear |
| Mustafa Reşat Dabak, Elif Sevinç, Sabah Tüzün, Emine Özel Gü. Evaluation of muscle mass in obesity, prediabetes and diabetes mellitus by different equations used for the measurement of muscle mass. Diabetes & metabolic syndrome. vol 13. issue 3. 2019-12-13. PMID:31235149. |
insulin resistance is one of risk factors for sarcopenia and there is no specific equation for the measurement of muscle mass. |
2019-12-13 |
2023-08-13 |
Not clear |
| Serpil M Deger, Jennifer R Hewlett, Jorge Gamboa, Charles D Ellis, Adriana M Hung, Edward D Siew, Cindy Mamnungu, Feng Sha, Aihua Bian, Thomas G Stewart, Naji N Abumrad, T Alp Ikizle. Insulin resistance is a significant determinant of sarcopenia in advanced kidney disease. American journal of physiology. Endocrinology and metabolism. vol 315. issue 6. 2019-08-26. PMID:29894202. |
insulin resistance is a significant determinant of sarcopenia in advanced kidney disease. |
2019-08-26 |
2023-08-13 |
human |
| Buenaventura Brito Díaz, Delia Almeida González, Fadoua Gannar, M Cristo Rodríguez Pérez, Antonio Cabrera de Leó. Myokines, physical activity, insulin resistance and autoimmune diseases. Immunology letters. vol 203. 2019-08-07. PMID:30194964. |
physical inactivity leads to an altered response of the secretion of myokines and resistance to them; this leads to a pro-inflammatory state that favors sarcopenia and fat accumulation, promoting the development of cardiovascular diseases, insulin resistance, and diabetes mellitus type 2. |
2019-08-07 |
2023-08-13 |
Not clear |
| Karn Wijarnpreecha, Panadeekarn Panjawatanan, Elizabeth Aby, Aijaz Ahmed, Donghee Ki. Nonalcoholic fatty liver disease in the over-60s: Impact of sarcopenia and obesity. Maturitas. vol 124. 2019-07-30. PMID:31097179. |
nafld is commonly seen in individuals with metabolic abnormalities, such as obesity and insulin resistance, which are closely associated with sarcopenia. |
2019-07-30 |
2023-08-13 |
Not clear |