| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher A Chapleau, Jane Lane, Jennifer Larimore, Wei Li, Lucas Pozzo-Miller, Alan K Perc. Recent Progress in Rett Syndrome and MeCP2 Dysfunction: Assessment of Potential Treatment Options. Future neurology. vol 8. issue 1. 2021-10-21. PMID:24348096. |
recent progress in rett syndrome and mecp2 dysfunction: assessment of potential treatment options. |
2021-10-21 |
2023-08-12 |
Not clear |
| Darren Goffin, Zhaolan Joe Zho. The neural circuit basis of Rett syndrome. Frontiers in biology. vol 7. issue 5. 2021-10-21. PMID:24999353. |
rett syndrome is an autism spectrum disorder caused by mutations in the gene encoding methyl-cpg binding protein (mecp2). |
2021-10-21 |
2023-08-13 |
Not clear |
| Deidra Young, Ami Bebbington, Nick de Klerk, Carol Bower, Lakshmi Nagarajan, Helen Leonar. The relationship between MECP2 mutation type and health status and service use trajectories over time in a Rett syndrome population. Research in autism spectrum disorders. vol 5. issue 1. 2021-10-20. PMID:21057653. |
the relationship between mecp2 mutation type and health status and service use trajectories over time in a rett syndrome population. |
2021-10-20 |
2023-08-12 |
human |
| Catarina Miranda-Lourenço, Sofia T Duarte, Cátia Palminha, Cláudia Gaspar, Tiago M Rodrigues, Teresa Magalhães-Cardoso, Nádia Rei, Mariana Colino-Oliveira, Rui Gomes, Sara Ferreira, Jéssica Rosa, Sara Xapelli, Judith Armstrong, Àngels García-Cazorla, Paulo Correia-de-Sá, Ana M Sebastião, Maria José Diógene. Impairment of adenosinergic system in Rett syndrome: Novel therapeutic target to boost BDNF signalling. Neurobiology of disease. vol 145. 2021-10-12. PMID:32798727. |
rett syndrome (rtt; omim#312750) is mainly caused by mutations in the x-linked mecp2 gene (methyl-cpg-binding protein 2 gene; omim*300005), which leads to impairments in the brain-derived neurotrophic factor (bdnf) signalling. |
2021-10-12 |
2023-08-13 |
Not clear |
| Hong-Wei Dong, Kirsty Erickson, Jessica R Lee, Jonathan Merritt, Cary Fu, Jeffrey L Neu. Detection of neurophysiological features in female R255X MeCP2 mutation mice. Neurobiology of disease. vol 145. 2021-10-12. PMID:32927061. |
rett syndrome (rtt) is a severe neurodevelopmental disorder (ndd) that is nearly always caused by loss of function mutations in methyl-cpg-binding protein 2 (mecp2) and shares many clinical features with other ndd. |
2021-10-12 |
2023-08-13 |
mouse |
| Irene Unterman, Idit Bloch, Simona Cazacu, Gila Kazimirsky, Bruria Ben-Zeev, Benjamin P Berman, Chaya Brodie, Yuval Tabac. Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome. eLife. vol 10. 2021-10-12. PMID:34355696. |
expanding the mecp2 network using comparative genomics reveals potential therapeutic targets for rett syndrome. |
2021-10-12 |
2023-08-13 |
human |
| Irene Unterman, Idit Bloch, Simona Cazacu, Gila Kazimirsky, Bruria Ben-Zeev, Benjamin P Berman, Chaya Brodie, Yuval Tabac. Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome. eLife. vol 10. 2021-10-12. PMID:34355696. |
inactivating mutations in the methyl-cpg binding protein 2 (mecp2) gene are the main cause of rett syndrome (rtt). |
2021-10-12 |
2023-08-13 |
human |
| Ian Adams, Tao Yang, Frank M Longo, David M Kat. Restoration of motor learning in a mouse model of Rett syndrome following long-term treatment with a novel small-molecule activator of TrkB. Disease models & mechanisms. vol 13. issue 11. 2021-10-08. PMID:33361117. |
reduced expression of brain-derived neurotrophic factor (bdnf) and impaired activation of the bdnf receptor, tropomyosin receptor kinase b (trkb; also known as ntrk2), are thought to contribute significantly to the pathophysiology of rett syndrome (rtt), a severe neurodevelopmental disorder caused by loss-of-function mutations in the x-linked gene encoding methyl-cpg-binding protein 2 (mecp2). |
2021-10-08 |
2023-08-13 |
mouse |
| Hao Xing, Ningren Cui, Christopher M Johnson, Zaakir Faisthalab, Chun Jian. Dual synaptic inhibitions of brainstem neurons by GABA and glycine with impact on Rett syndrome. Journal of cellular physiology. vol 236. issue 5. 2021-09-29. PMID:33169374. |
rett syndrome (rtt) is a neurodevelopmental disease caused mostly by mutations in the mecp2 gene. |
2021-09-29 |
2023-08-13 |
mouse |
| Jason Arsenault, Alexander W M Hooper, Shervin Gholizadeh, Tian Kong, Laura K Pacey, Enea Koxhioni, Yosuke Niibori, James H Eubanks, Lu-Yang Wang, David R Hampso. Interregulation between fragile X mental retardation protein and methyl CpG binding protein 2 in the mouse posterior cerebral cortex. Human molecular genetics. vol 29. issue 23. 2021-09-28. PMID:33084871. |
several x-linked neurodevelopmental disorders including rett syndrome, induced by mutations in the mecp2 gene, and fragile x syndrome (fxs), caused by mutations in the fmr1 gene, share autism-related features. |
2021-09-28 |
2023-08-13 |
mouse |
| Jason Arsenault, Alexander W M Hooper, Shervin Gholizadeh, Tian Kong, Laura K Pacey, Enea Koxhioni, Yosuke Niibori, James H Eubanks, Lu-Yang Wang, David R Hampso. Interregulation between fragile X mental retardation protein and methyl CpG binding protein 2 in the mouse posterior cerebral cortex. Human molecular genetics. vol 29. issue 23. 2021-09-28. PMID:33084871. |
here, we report a homeostatic relationship between these two key regulators of gene expression in mouse models of fxs (fmr1 knockout (ko)) and rett syndrome (mecp2 ko). |
2021-09-28 |
2023-08-13 |
mouse |
| Katherine S Adcock, Abigail E Blount, Robert A Morrison, Amanda Alvarez-Dieppa, Michael P Kilgard, Crystal T Engineer, Seth A Hay. Deficits in skilled motor and auditory learning in a rat model of Rett syndrome. Journal of neurodevelopmental disorders. vol 12. issue 1. 2021-09-17. PMID:32988374. |
rett syndrome is an x-linked neurodevelopmental disorder caused by a mutation in the gene mecp2. |
2021-09-17 |
2023-08-13 |
mouse |
| Javier Flores Gutiérrez, Claudio De Felice, Giulia Natali, Silvia Leoncini, Cinzia Signorini, Joussef Hayek, Enrico Tongiorg. Protective role of mirtazapine in adult female Mecp2 Journal of neurodevelopmental disorders. vol 12. issue 1. 2021-09-17. PMID:32988385. |
protective role of mirtazapine in adult female mecp2 rett syndrome (rtt), an x-linked neurodevelopmental rare disease mainly caused by mecp2-gene mutations, is a prototypic intellectual disability disorder. |
2021-09-17 |
2023-08-13 |
mouse |
| Hyeong-Min Lee, M Bram Kuijer, Nerea Ruiz Blanes, Ellen P Clark, Megumi Aita, Lorena Galiano Arjona, Agnieszka Kokot, Noah Sciaky, Jeremy M Simon, Sanchita Bhatnagar, Benjamin D Philpot, Andrea Ceras. A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance. Journal of neurodevelopmental disorders. vol 12. issue 1. 2021-09-17. PMID:33172406. |
rett syndrome (rtt) is a neurodevelopmental disorder caused by mutations in the x-linked methyl-cpg binding protein 2 (mecp2) gene. |
2021-09-17 |
2023-08-13 |
Not clear |
| Bidzina Kanashvili, Kenneth J Rogers, Michael Wade Shrader, Freeman Miller, Kirk W Dabney, Jason J Howar. Hip Displacement in MECP2 Disorders: Prevalence and Risk Factors. Journal of pediatric orthopedics. vol 41. issue 9. 2021-09-15. PMID:34334698. |
methyl-cpg binding protein 2 (mecp2) disorders, including rett syndrome and mecp2 duplication syndrome, are typified by profound intellectual disability, spasticity, and decline in gross motor function. |
2021-09-15 |
2023-08-13 |
Not clear |
| Yingyao Shao, Sameer S Bajikar, Harini P Tirumala, Manuel Cantu Gutierrez, Joshua D Wythe, Huda Y Zoghb. Identification and characterization of conserved noncoding Genes & development. vol 35. issue 7-8. 2021-09-09. PMID:33737384. |
identification and characterization of conserved noncoding while changes in mecp2 dosage cause rett syndrome (rtt) and |
2021-09-09 |
2023-08-13 |
Not clear |
| Ketan Marballi, Jessica L MacDonal. Proteomic and transcriptional changes associated with MeCP2 dysfunction reveal nodes for therapeutic intervention in Rett syndrome. Neurochemistry international. vol 148. 2021-09-08. PMID:34048843. |
proteomic and transcriptional changes associated with mecp2 dysfunction reveal nodes for therapeutic intervention in rett syndrome. |
2021-09-08 |
2023-08-13 |
Not clear |
| Ketan Marballi, Jessica L MacDonal. Proteomic and transcriptional changes associated with MeCP2 dysfunction reveal nodes for therapeutic intervention in Rett syndrome. Neurochemistry international. vol 148. 2021-09-08. PMID:34048843. |
mutations in the methyl-cpg binding protein 2 (mecp2) gene cause rett syndrome (rtt), an x-linked neurodevelopmental disorder predominantly impacting females. |
2021-09-08 |
2023-08-13 |
Not clear |
| David Ortega-Alarcon, Rafael Claveria-Gimeno, Sonia Vega, Olga C Jorge-Torres, Manel Esteller, Olga Abian, Adrian Velazquez-Campo. Molecular Context-Dependent Effects Induced by Rett Syndrome-Associated Mutations in MeCP2. Biomolecules. vol 10. issue 11. 2021-09-07. PMID:33182787. |
loss-of-function mutations in mecp2 result in rett syndrome (rtt), a neurodevelopmental disorder that is the main cause of mental retardation in females. |
2021-09-07 |
2023-08-13 |
Not clear |
| Susan A Rose, Sam V Wass, Jeffery J Jankowski, Aleksandra Djuki. Measures of attention in Rett syndrome: Internal consistency reliability. Neuropsychology. vol 35. issue 6. 2021-09-06. PMID:34096738. |
rett syndrome (rtt), an x-linked neurodevelopmental disorder caused by spontaneous mutations in the mecp2 gene, is characterized by profound impairments in expressive language and purposeful hand use. |
2021-09-06 |
2023-08-13 |
Not clear |