| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebekah Tillotson, Justyna Cholewa-Waclaw, Kashyap Chhatbar, John C Connelly, Sophie A Kirschner, Shaun Webb, Martha V Koerner, Jim Selfridge, David A Kelly, Dina De Sousa, Kyla Brown, Matthew J Lyst, Skirmantas Kriaucionis, Adrian Bir. Neuronal non-CG methylation is an essential target for MeCP2 function. Molecular cell. vol 81. issue 6. 2021-04-01. PMID:33561390. |
dna methylation is implicated in neuronal biology via the protein mecp2, the mutation of which causes rett syndrome. |
2021-04-01 |
2023-08-13 |
mouse |
| Rebekah Tillotson, Justyna Cholewa-Waclaw, Kashyap Chhatbar, John C Connelly, Sophie A Kirschner, Shaun Webb, Martha V Koerner, Jim Selfridge, David A Kelly, Dina De Sousa, Kyla Brown, Matthew J Lyst, Skirmantas Kriaucionis, Adrian Bir. Neuronal non-CG methylation is an essential target for MeCP2 function. Molecular cell. vol 81. issue 6. 2021-04-01. PMID:33561390. |
the results support the notion that the delayed onset of rett syndrome is due to the simultaneous post-natal accumulation of mcac and its reader mecp2. |
2021-04-01 |
2023-08-13 |
mouse |
| Rebekah Tillotson, Justyna Cholewa-Waclaw, Kashyap Chhatbar, John C Connelly, Sophie A Kirschner, Shaun Webb, Martha V Koerner, Jim Selfridge, David A Kelly, Dina De Sousa, Kyla Brown, Matthew J Lyst, Skirmantas Kriaucionis, Adrian Bir. Neuronal non-CG methylation is an essential target for MeCP2 function. Molecular cell. vol 81. issue 6. 2021-04-01. PMID:33561390. |
intriguingly, genes dysregulated in both mecp2 null and domain-swap mice are implicated in other neurological disorders, potentially highlighting targets of relevance to the rett syndrome phenotype. |
2021-04-01 |
2023-08-13 |
mouse |
| Satoru Takahashi, Ryo Takeguchi, Mami Kuroda, Ryosuke Tanak. Atypical Rett syndrome in a girl with mosaic triple X and MECP2 variant. Molecular genetics & genomic medicine. vol 8. issue 3. 2021-03-29. PMID:31943886. |
atypical rett syndrome in a girl with mosaic triple x and mecp2 variant. |
2021-03-29 |
2023-08-13 |
Not clear |
| Satoru Takahashi, Ryo Takeguchi, Mami Kuroda, Ryosuke Tanak. Atypical Rett syndrome in a girl with mosaic triple X and MECP2 variant. Molecular genetics & genomic medicine. vol 8. issue 3. 2021-03-29. PMID:31943886. |
rett syndrome (rtt) is a neurodevelopmental disorder that predominantly affects girls, resulting from a loss-of-function variant in x-linked mecp2. |
2021-03-29 |
2023-08-13 |
Not clear |
| Katherine S Adcock, Collin Chandler, Elizabeth P Buell, Bleyda R Solorzano, Kristofer W Loerwald, Michael S Borland, Crystal T Enginee. Vagus nerve stimulation paired with tones restores auditory processing in a rat model of Rett syndrome. Brain stimulation. vol 13. issue 6. 2021-03-29. PMID:32800964. |
rett syndrome is a rare neurological disorder associated with a mutation in the x-linked gene mecp2. |
2021-03-29 |
2023-08-13 |
rat |
| Katherine S Adcock, Collin Chandler, Elizabeth P Buell, Bleyda R Solorzano, Kristofer W Loerwald, Michael S Borland, Crystal T Enginee. Vagus nerve stimulation paired with tones restores auditory processing in a rat model of Rett syndrome. Brain stimulation. vol 13. issue 6. 2021-03-29. PMID:32800964. |
the rodent mecp2 model exhibits many of the classic neural abnormalities and behavioral deficits observed in individuals with rett syndrome. |
2021-03-29 |
2023-08-13 |
rat |
| Katherine S Adcock, Collin Chandler, Elizabeth P Buell, Bleyda R Solorzano, Kristofer W Loerwald, Michael S Borland, Crystal T Enginee. Vagus nerve stimulation paired with tones restores auditory processing in a rat model of Rett syndrome. Brain stimulation. vol 13. issue 6. 2021-03-29. PMID:32800964. |
similar to individuals with rett syndrome, both auditory discrimination ability and auditory cortical responses are impaired in heterozygous mecp2 rats. |
2021-03-29 |
2023-08-13 |
rat |
| Annarita Patrizi, Patricia N Awad, Bidisha Chattopadhyaya, Chloe Li, Graziella Di Cristo, Michela Fagiolin. Accelerated Hyper-Maturation of Parvalbumin Circuits in the Absence of MeCP2. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 1. 2021-03-22. PMID:31038696. |
methyl-cpg-binding protein 2 (mecp2) mutations are the primary cause of rett syndrome, a severe neurodevelopmental disorder. |
2021-03-22 |
2023-08-13 |
mouse |
| Alex de Mendoza, Daniel Poppe, Sam Buckberry, Jahnvi Pflueger, Caroline B Albertin, Tasman Daish, Stephanie Bertrand, Elisa de la Calle-Mustienes, José Luis Gómez-Skarmeta, Joseph R Nery, Joseph R Ecker, Boris Baer, Clifton W Ragsdale, Frank Grützner, Hector Escriva, Byrappa Venkatesh, Ozren Bogdanovic, Ryan Liste. The emergence of the brain non-CpG methylation system in vertebrates. Nature ecology & evolution. vol 5. issue 3. 2021-03-19. PMID:33462491. |
non-cpg methylation plays a critical regulatory role in cognitive function, which is mediated by the binding of mecp2, the transcriptional regulator that when mutated causes rett syndrome. |
2021-03-19 |
2023-08-13 |
Not clear |
| Mari Wold Henriksen, Hilde Breck, Yngve Sejersted, Trond Diseth, Stephen von Tetzchner, Benedicte Paus, Ola H Skjelda. Genetic and clinical variations in a Norwegian sample diagnosed with Rett syndrome. Brain & development. vol 42. issue 7. 2021-03-08. PMID:32336485. |
rett syndrome (rtt) is a neurodevelopmental disorder mainly caused by mutations in mecp2. |
2021-03-08 |
2023-08-13 |
Not clear |
| Annika Schmidt, Hui Zhang, M Cristina Cardos. MeCP2 and Chromatin Compartmentalization. Cells. vol 9. issue 4. 2021-02-25. PMID:32260176. |
methyl-cpg binding protein 2 (mecp2) is a multifunctional epigenetic reader playing a role in transcriptional regulation and chromatin structure, which was linked to rett syndrome in humans. |
2021-02-25 |
2023-08-13 |
Not clear |
| Giorgia Napoletani, Daniele Vigli, Livia Cosentino, Maddalena Grieco, Maria Cristina Talamo, Enza Lacivita, Marcello Leopoldo, Giovanni Laviola, Andrea Fuso, Maria d'Erme, Bianca De Filippi. Stimulation of the Serotonin Receptor 7 Restores Brain Histone H3 Acetylation and MeCP2 Corepressor Protein Levels in a Female Mouse Model of Rett Syndrome. Journal of neuropathology and experimental neurology. vol 80. issue 3. 2021-02-23. PMID:33598674. |
stimulation of the serotonin receptor 7 restores brain histone h3 acetylation and mecp2 corepressor protein levels in a female mouse model of rett syndrome. |
2021-02-23 |
2023-08-13 |
mouse |
| Giorgia Napoletani, Daniele Vigli, Livia Cosentino, Maddalena Grieco, Maria Cristina Talamo, Enza Lacivita, Marcello Leopoldo, Giovanni Laviola, Andrea Fuso, Maria d'Erme, Bianca De Filippi. Stimulation of the Serotonin Receptor 7 Restores Brain Histone H3 Acetylation and MeCP2 Corepressor Protein Levels in a Female Mouse Model of Rett Syndrome. Journal of neuropathology and experimental neurology. vol 80. issue 3. 2021-02-23. PMID:33598674. |
rett syndrome (rtt) is a rare neurological disorder caused by mutations in the x-linked mecp2 gene, characterized by severe behavioral and physiological impairments for which no cure is available. |
2021-02-23 |
2023-08-13 |
mouse |
| b' Katrina V Good, John B Vincent, Juan Ausi\\xc3\\xb. MeCP2: The Genetic Driver of Rett Syndrome Epigenetics. Frontiers in genetics. vol 12. 2021-02-10. PMID:33552148.' |
mecp2: the genetic driver of rett syndrome epigenetics. |
2021-02-10 |
2023-08-13 |
Not clear |
| b' Katrina V Good, John B Vincent, Juan Ausi\\xc3\\xb. MeCP2: The Genetic Driver of Rett Syndrome Epigenetics. Frontiers in genetics. vol 12. 2021-02-10. PMID:33552148.' |
mutations in methyl cpg binding protein 2 (mecp2) are the major cause of rett syndrome (rtt), a rare neurodevelopmental disorder with a notable period of developmental regression following apparently normal initial development. |
2021-02-10 |
2023-08-13 |
Not clear |
| Friederike Ehrhart, Annika Jacobsen, Maria Rigau, Mattia Bosio, Rajaram Kaliyaperumal, Jeroen F J Laros, Egon L Willighagen, Alfonso Valencia, Marco Roos, Salvador Capella-Gutierrez, Leopold M G Curfs, Chris T Evel. A catalogue of 863 Rett-syndrome-causing MECP2 mutations and lessons learned from data integration. Scientific data. vol 8. issue 1. 2021-02-05. PMID:33452270. |
rett syndrome (rtt) is a rare neurological disorder mostly caused by a genetic variation in mecp2. |
2021-02-05 |
2023-08-13 |
Not clear |
| Aya Ito-Ishida, Steven A Baker, Roy V Sillitoe, Yaling Sun, Jian Zhou, Yukiteru Ono, Junichi Iwakiri, Michisuke Yuzaki, Huda Y Zoghb. MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 45. 2021-02-01. PMID:33046553. |
methyl-cpg binding protein 2 (mecp2) is a nuclear protein critical for normal brain function, and both depletion and overexpression of mecp2 lead to severe neurodevelopmental disease, rett syndrome (rtt) and |
2021-02-01 |
2023-08-13 |
mouse |
| Sara Brunetti, Daniel E Lumsde. Rett Syndrome as a movement and motor disorder - A narrative review. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 28. 2021-01-20. PMID:32807681. |
rett syndrome (rtt) is neurodevelopmental disorder affecting approximately 1:10000-15000 live female births, commonly associated with mecp2 gene mutations. |
2021-01-20 |
2023-08-13 |
Not clear |
| Sampathkumar Rangasamy, Shannon Olfers, Brittany Gerald, Alex Hilbert, Sean Svejda, Vinodh Narayana. Reduced neuronal size and mTOR pathway activity in the Mecp2 A140V Rett syndrome mouse model. F1000Research. vol 5. 2021-01-09. PMID:27781091. |
reduced neuronal size and mtor pathway activity in the mecp2 a140v rett syndrome mouse model. |
2021-01-09 |
2023-08-13 |
mouse |