| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Wu, Qinghua Zhu, Yi Yao, Zhaoyang Shi, Chaojie Jin, Leilei Che. Exosome miR-23a-3p From Osteoblast Alleviates Spinal Cord Ischemia/Reperfusion Injury by Down-regulating KLF3-activated CCNL2 Transcription. Developmental neuroscience. 2021-12-22. PMID:34937039. |
spinal cord ischemia/reperfusion injury (sciri) is usually caused by spinal surgery or aortic aneurysm surgery and can eventually lead to paralysis or paraplegia and neurological dysfunction. |
2021-12-22 |
2023-08-13 |
Not clear |
| Jared D Sydney-Smith, Aline B Spejo, Philippa M Warren, Lawrence D F Moo. Peripherally delivered Adeno-associated viral vectors for spinal cord injury repair. Experimental neurology. 2021-12-13. PMID:34896114. |
accordingly, spinal cord injury (sci) can result in catastrophe for multiple body systems including muscle paralysis affecting movement and loss of normal sensation, as well as neuropathic pain, spasticity, reduced fertility and autonomic dysreflexia. |
2021-12-13 |
2023-08-13 |
human |
| Jingjuan Li, Xin Cheng, Dan Fu, Yi Liang, Cai Chen, Wei Deng, Liang H. Autophagy of spinal microglia affects the activation of microglia through the PI3K/AKT/mTOR signaling pathway. Neuroscience. 2021-12-13. PMID:34902496. |
delayed paralysis occurs within some patients suffered from ischemic spinal cord injury (isci) due to the aorta occlusion during the repair surgery of thoracic and thoracoabdominal aortic aneurysms. |
2021-12-13 |
2023-08-13 |
mouse |
| Ghaith J Androwis, Amanda Engler, Sameer Rana, Steven Kirshblum, Guang H Yu. The Rehabilitation Effects of Myoelectric Powered Wearable Orthotics on Improving Upper Extremity Function in Persons with SCI. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2021. 2021-12-11. PMID:34892317. |
upper extremity (ue) weakness and/or paralysis following spinal cord injury (sci) can lead to a limited capacity to perform activities of daily living (adl). |
2021-12-11 |
2023-08-13 |
human |
| Zhuo Zhang, Lili Zhao, Manman Song, Jilong Luo, Hanghang Liu, Kun Xue, Chengshi Huang, Hongyan Chen, Junwei G. Providencia heimbachae Associated with Post-weaning Diarrhea in Piglets: Identification, Phenotype, and Pathogenesis. Current microbiology. vol 79. issue 1. 2021-12-09. PMID:34878563. |
histopathology studies on nerve tissue of piglets that developed hindlimb paralysis showed microglia cell infiltration and neuron damage in the spinal cord. |
2021-12-09 |
2023-08-13 |
mouse |
| Soshi Samejima, Aiva M Ievins, Adrien Boissenin, Nicholas M Tolley, Abed Khorasani, Sarah E Mondello, Chet T Morit. Automated Lever Task with Minimum Antigravity Movement for Rats with Cervical Spinal Cord Injury. Journal of neuroscience methods. 2021-12-05. PMID:34863839. |
although there is currently no cure for paralysis due to spinal cord injury (sci), the highest treatment priority is restoring arm and hand function for people with cervical sci. |
2021-12-05 |
2023-08-13 |
rat |
| Hamdy Awad, Alexander Efanov, Jayanth Rajan, Andrew Denney, Bradley Gigax, Peter Kobalka, Hesham Kelani, D Michele Basso, John Bozinovski, Esmerina Til. Histological Findings After Aortic Cross-Clamping in Preclinical Animal Models. Journal of neuropathology and experimental neurology. vol 80. issue 10. 2021-11-30. PMID:34534333. |
spinal cord ischemic injury and paralysis are devastating complications after open surgical repair of thoracoabdominal aortic aneurysms. |
2021-11-30 |
2023-08-13 |
Not clear |
| Maryam Lale Ataei, Mohammad Karimipour, Parviz Shahabi, Roghiyeh Pashaei-Asl, Esmaeil Ebrahimie, Maryam Pashaias. The Restorative Effect of Human Amniotic Fluid Stem Cells on Spinal Cord Injury. Cells. vol 10. issue 10. 2021-11-29. PMID:34685545. |
spinal cord injury (sci) is a debilitating condition within the neural system which is clinically manifested by sensory-motor dysfunction, leading, in some cases, to neural paralysis for the rest of the patient's life. |
2021-11-29 |
2023-08-13 |
human |
| Aseem Setia, Jasween Bhatia, Sankha Bhattachary. An Overview of Acute Flaccid Myelitis. CNS & neurological disorders drug targets. 2021-11-26. PMID:34823462. |
acute flaccid myelitis is defined by the presence of acute flaccid paralysis (afp) and a spinal cord lesion on magnetic resonance imaging that is primarily limited to the grey matter. |
2021-11-26 |
2023-08-13 |
Not clear |
| Pria Anan. Infectious Myelopathies. Seminars in neurology. vol 41. issue 3. 2021-11-23. PMID:34010967. |
clinical spinal cord syndromes related to infection are varied, including transverse myelitis, acute flaccid paralysis related to anterior horn cell involvement, spinal cord compression, chronic spastic paraparesis, and myeloradiculitis. |
2021-11-23 |
2023-08-13 |
Not clear |
| Ni Komang Sri Dewi Untari, Kurnia Kusumastuti, Guritno Suryokusumo, I Ketut Sudian. Protective Effect of Hyperbaric Oxygen Treatment on Axon Degeneration after Acute Motor Axonal Neuropathy. Autoimmune diseases. vol 2021. 2021-11-19. PMID:34790416. |
acute motor axonal neuropathy (aman) is a disease that leads to acute flaccid paralysis and may result from the binding of antibody and antigen to the spinal cord. |
2021-11-19 |
2023-08-13 |
rabbit |
| Karim Sahbani, Christopher P Cardozo, William A Bauman, Hesham A Tawfee. Inhibition of TGF-β signaling attenuates disuse-induced trabecular bone loss after spinal cord injury in male mice. Endocrinology. 2021-11-18. PMID:34791098. |
thus, 16-week-old male mice underwent sham or spinal cord contusion injury to cause complete hindlimb paralysis. |
2021-11-18 |
2023-08-13 |
mouse |
| Luke Stuart Urban, Michael A Thornton, Katie L Ingraham Dixie, Erica A Dale, Hui Zhong, Patricia E Phelps, Joel W Burdick, V Reggie Edgerto. Formation of a novel supraspinal-spinal connectome that relearns the same motor task after complete paralysis. Journal of neurophysiology. vol 126. issue 3. 2021-11-17. PMID:34406891. |
having observed that electrical spinal cord stimulation and training enabled four patients with paraplegia with motor complete paralysis to regain voluntary leg movement, the underlying mechanisms involved in forming the newly established supraspinal-spinal functional connectivity have become of great interest. |
2021-11-17 |
2023-08-13 |
Not clear |
| Ziling Liao, Xiuzhen Yang, Wei Wang, Weiyue Deng, Yuying Zhang, Aishi Song, Bin Ni, Huifang Zhao, Shusheng Zhang, Zhiyuan L. hucMSCs transplantation promotes locomotor function recovery, reduces apoptosis and inhibits demyelination after SCI in rats. Neuropeptides. vol 86. 2021-11-12. PMID:33486279. |
spinal cord injury (sci) can cause a variety of cells apoptosis, neurodegeneration, and eventually permanent paralysis. |
2021-11-12 |
2023-08-13 |
human |
| Lorenzo Alibard. Growth associated protein 43 and neurofilament immunolabeling in the transected lumbar spinal cord of lizard indicates limited axonal regeneration. Neural regeneration research. vol 17. issue 5. 2021-11-10. PMID:34558530. |
the few regenerating-sprouting axons within the bridge reconnect the caudal with the rostral stumps of the spinal cord, and likely contribute to activate the neural circuits that sustain the limited but important recovery of hind-limb movements after initial paralysis. |
2021-11-10 |
2023-08-13 |
Not clear |
| Andrew R Brown, Marina Martine. Chronic inactivation of the contralesional hindlimb motor cortex after thoracic spinal cord hemisection impedes locomotor recovery in the rat. Experimental neurology. vol 343. 2021-11-09. PMID:34081986. |
in adult rats, left hindlimb paralysis was induced by sectioning half of the spinal cord at the thoracic level (hemisection) and we used a continuous infusion of muscimol (gaba |
2021-11-09 |
2023-08-13 |
rat |
| Dylan A McCreedy, Frank L Jalufka, Madison E Platt, Sun Won Min, Megan A Kirchhoff, Anna L Pritchard, Shelby K Reid, Ronald Manlapaz, Eszter Mihaly, Jessica C Butts, Nisha R Iyer, Shelly E Sakiyama-Elbert, Steven A Crone, Todd C McDevit. Passive Clearing and 3D Lightsheet Imaging of the Intact and Injured Spinal Cord in Mice. Frontiers in cellular neuroscience. vol 15. 2021-11-08. PMID:34408627. |
spinal cord injury (sci) permanently disrupts neural circuits through initial mechanical damage, as well as a cascade of secondary injury events that further expand the spinal cord lesion, resulting in permanent paralysis. |
2021-11-08 |
2023-08-13 |
mouse |
| Dana M Otzel, Hui Jean Kok, Zachary A Graham, Elisabeth R Barton, Joshua F Yarro. Pharmacologic approaches to prevent skeletal muscle atrophy after spinal cord injury. Current opinion in pharmacology. vol 60. 2021-11-08. PMID:34461564. |
skeletal muscle atrophy is a hallmark of severe spinal cord injury (sci) that is precipitated by the neural insult and paralysis. |
2021-11-08 |
2023-08-13 |
Not clear |
| Richard J Zeman, Xialing Wen, Nengtai Ouyang, Abraham M Brown, Joseph D Etlinge. Role of the Polyol Pathway in Locomotor Recovery and Wallerian Degeneration after Spinal Cord Contusion Injury. Neurotrauma reports. vol 2. issue 1. 2021-11-06. PMID:34738094. |
spinal cord contusion injury leads to wallerian degeneration of axonal tracts, resulting in irreversible paralysis. |
2021-11-06 |
2023-08-13 |
rat |
| Lan Cheng, Armin Sami, Biswarup Ghosh, Mark W Urban, Nicolette M Heinsinger, Sophia S Liang, George M Smith, Megan C Wright, Shuxin Li, Angelo C Lepor. LAR inhibitory peptide promotes recovery of diaphragm function and multiple forms of respiratory neural circuit plasticity after cervical spinal cord injury. Neurobiology of disease. vol 147. 2021-11-01. PMID:33127470. |
we tested the effects of a novel lar inhibitory peptide in rats after hemisection at cervical level 2, a sci model in which bulbospinal inspiratory neural circuitry originating in the medullary rostral ventral respiratory group (rvrg) becomes disconnected from phrenic motor neuron (phmn) targets in cervical spinal cord, resulting in persistent partial-to-complete diaphragm paralysis. |
2021-11-01 |
2023-08-13 |
rat |