| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ashley Munie Gardner, Jeffrey R Atkinson, Nicole M Wilkinson, Andrew D Jerome, Calli E Bellinger, Andrew R Sas, Benjamin M Sega. TAM receptor signaling dictates lesion location and clinical phenotype during experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 375. 2023-01-28. PMID:36708633. |
experimental autoimmune encephalomyelitis (eae), induced by the adoptive transfer of th17 cells, typically presents with ascending paralysis and inflammatory demyelination of the spinal cord. |
2023-01-28 |
2023-08-14 |
Not clear |
| Matrone Carmel. The paradigm of amyloid precursor protein in amyotrophic lateral sclerosis: The potential role of the Computational and structural biotechnology journal. vol 21. 2023-01-26. PMID:36698966. |
it is clinically characterized by the selective and progressive loss of motor neurons in the motor cortex, brain stem, and spinal cord, ultimately leading to muscle atrophy and rapidly progressive paralysis. |
2023-01-26 |
2023-08-14 |
Not clear |
| Shao-Ming Wang, Jung-Yu C Hsu, Chiung-Yuan Ko, Hsiang-En Wu, Yu-Wei Hsiao, Ju-Ming Wan. Astrocytic Cebpd Regulates Pentraxin 3 Expression to Promote Fibrotic Scar Formation After Spinal Cord Injury. Molecular neurobiology. 2023-01-12. PMID:36633805. |
astroglial-fibrotic scars resulted from spinal cord injury affect motor and sensory function, leading to paralysis. |
2023-01-12 |
2023-08-14 |
Not clear |
| Elisa Duranti, Chiara Vill. Molecular Investigations of Protein Aggregation in the Pathogenesis of Amyotrophic Lateral Sclerosis. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36614144. |
amyotrophic lateral sclerosis (als) is a devastating progressive neurodegenerative disorder characterized by selective loss of lower and upper motor neurons (mns) in the brain and spinal cord, resulting in paralysis and eventually death due to respiratory insufficiency. |
2023-01-08 |
2023-08-14 |
Not clear |
| Bandar M Hetaimish, Ahmed Q Alturkistany, Hassan A Ahmed, Eid A Almasoudi, Abubakr S Alzwaihr. Spinal Cord Ischemia After Lower Extremity Surgery in Pediatric Osteogenesis Imperfecta With Thoracic Kyphoscoliosis: Tertiary Care Center Experience in Jeddah, Saudi Arabia. Cureus. vol 14. issue 11. 2022-12-21. PMID:36540443. |
early postoperatively, he developed spinal paralysis at the level of t4-t7, and an mri of the spine demonstrated high signal intensity within the spinal cord from level t3 to t7. |
2022-12-21 |
2023-08-14 |
Not clear |
| Saad Javeed, Jacob K Greenberg, Justin K Zhang, Christopher F Dibble, Jawad M Khalifeh, Ying Liu, Thomas J Wilson, Lynda J Yang, Yikyung Park, Wilson Z Ra. Derivation and Validation of a Clinical Prediction Rule for Upper Limb Functional Outcomes After Traumatic Cervical Spinal Cord Injury. JAMA network open. vol 5. issue 12. 2022-12-21. PMID:36542381. |
traumatic cervical spinal cord injury (sci) can result in debilitating paralysis. |
2022-12-21 |
2023-08-14 |
Not clear |
| Yifei Zhou, Lin Li, Chenghuang Mao, Dongsheng Zho. Astragaloside IV ameliorates spinal cord injury through controlling ferroptosis in H Annals of translational medicine. vol 10. issue 21. 2022-12-05. PMID:36467371. |
astragaloside iv ameliorates spinal cord injury through controlling ferroptosis in h spinal cord injury (sci) is associated with significant paralysis and high fatality. |
2022-12-05 |
2023-08-14 |
Not clear |
| Shylesh Bhaskaran, Gaurav Kumar, Nidheesh Thadathil, Katarzyna M Piekarz, Sabira Mohammed, Sergio Dominguez Lopez, Rizwan Qaisar, Dorothy Walton, Jacob L Brown, Ashley Murphy, Nataliya Smith, Debra Saunders, Michael J Beckstead, Scott Plafker, Tommy L Lewis, Rheal Towner, Sathyaseelan S Deepa, Arlan Richardson, Robert C Axtell, Holly Van Remme. Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis. Redox biology. vol 59. 2022-12-05. PMID:36470129. |
phenotypically, i-mn-sod2 ko mice experienced hindlimb paralysis and clasping behavior associated with extensive demyelination and reduced nerve conduction velocity, axonal degeneration, enhanced blood brain barrier permeability, elevated inflammatory cytokines, microglia activation, infiltration of neutrophils and necroptosis in spinal cord. |
2022-12-05 |
2023-08-14 |
mouse |
| Shylesh Bhaskaran, Gaurav Kumar, Nidheesh Thadathil, Katarzyna M Piekarz, Sabira Mohammed, Sergio Dominguez Lopez, Rizwan Qaisar, Dorothy Walton, Jacob L Brown, Ashley Murphy, Nataliya Smith, Debra Saunders, Michael J Beckstead, Scott Plafker, Tommy L Lewis, Rheal Towner, Sathyaseelan S Deepa, Arlan Richardson, Robert C Axtell, Holly Van Remme. Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis. Redox biology. vol 59. 2022-12-05. PMID:36470129. |
overall, our findings show that loss of mnsod in spinal cord promotes a phenotype of demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis. |
2022-12-05 |
2023-08-14 |
mouse |
| Yanfeng Huang, Xie Zhang, Qionghui Huang, Yaoxing Dou, Chang Qu, Qingqing Xu, Qiuju Yuan, Yan-Fang Xian, Zhi-Xiu Li. Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion. Inflammation and regeneration. vol 42. issue 1. 2022-12-01. PMID:36456978. |
brachial plexus avulsion (bpa) physically involves the detachment of spinal nerve roots themselves and the associated spinal cord segment, leading to permanent paralysis of motor function of the upper limb. |
2022-12-01 |
2023-08-14 |
rat |
| Chen Jin, Rui Zhu, Zhan-Wei Wang, Yi Li, Hao-Fei Ni, Meng-Lei Xu, Liang-Dong Zheng, Yu-Ting Cao, Yi-Ting Yang, Wei Xu, Jian-Jie Wang, Ning Xie, Li-Ming Chen. Dynamic changes in mechanical properties of the adult rat spinal cord after injury. Acta biomaterialia. 2022-11-26. PMID:36435440. |
statement of significance: spinal cord injury (sci) is a devastating disease often leading to permanent paralysis. |
2022-11-26 |
2023-08-14 |
rat |
| George H Parkinso. Acute Congestion of the Lumbar Region of the Spinal Cord, Cystitis, Pyelitis, Acute Parenchymatous Nephritis-Posterior Paralysis of the Horse. The Journal of comparative medicine and surgery. vol 2. issue 3. 2022-11-17. PMID:36390125. |
acute congestion of the lumbar region of the spinal cord, cystitis, pyelitis, acute parenchymatous nephritis-posterior paralysis of the horse. |
2022-11-17 |
2023-08-14 |
Not clear |
| Faisal R Jahangiri, Rafia H Jahangiri, Hooria Asad, Laila Farooq, Wadana H Khatta. Scoliosis Corrective Surgery With Continuous Intraoperative Neurophysiological Monitoring (IONM). Cureus. vol 14. issue 10. 2022-11-16. PMID:36381772. |
this correction weight may cause spinal cord functional compromise and may result in postoperative paresis or paralysis. |
2022-11-16 |
2023-08-14 |
Not clear |
| Claudia Kathe, Michael A Skinnider, Thomas H Hutson, Nicola Regazzi, Matthieu Gautier, Robin Demesmaeker, Salif Komi, Steven Ceto, Nicholas D James, Newton Cho, Laetitia Baud, Katia Galan, Kaya J E Matson, Andreas Rowald, Kyungjin Kim, Ruijia Wang, Karen Minassian, John O Prior, Leonie Asboth, Quentin Barraud, Stéphanie P Lacour, Ariel J Levine, Fabien Wagner, Jocelyne Bloch, Jordan W Squair, Grégoire Courtin. The neurons that restore walking after paralysis. Nature. 2022-11-09. PMID:36352232. |
a spinal cord injury interrupts pathways from the brain and brainstem that project to the lumbar spinal cord, leading to paralysis. |
2022-11-09 |
2023-08-14 |
Not clear |
| Carmen Delia Nistor-Cseppento, Anamaria Gherle, Nicoleta Negrut, Simona Gabriela Bungau, Anca Maria Sabau, Andrei-Flavius Radu, Alexa Florina Bungau, Delia Mirela Tit, Bogdan Uivaraseanu, Timea Claudia Ghitea, Diana Uivarosa. The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications. Medicina (Kaunas, Lithuania). vol 58. issue 10. 2022-10-27. PMID:36295607. |
voluntary muscle paralysis caused by spinal cord damage affects the patient's independence. |
2022-10-27 |
2023-08-14 |
human |
| Renato Baptista, Francesco Salvaggio, Caterina Cavallo, Serena Pizzocaro, Svonko Galasso, Micaela Schmid, Alessandro Marco De Nunzi. Training-Induced Muscle Fatigue with a Powered Lower-Limb Exoskeleton: A Preliminary Study on Healthy Subjects. Medical sciences (Basel, Switzerland). vol 10. issue 4. 2022-10-24. PMID:36278525. |
powered lower-limb exoskeletons represent a promising technology for helping the upright stance and gait of people with lower-body paralysis or severe paresis from spinal cord injury. |
2022-10-24 |
2023-08-14 |
human |
| Kuan-Yu Chen, Chiao-Shin Lu, Cheng-Yoong Pang, Chin-Jui Ho, Kuo-Chen Wu, Hsiu-Wei Yang, Hsin-Lin Lai, Yijuang Chern, Chun-Jung Li. Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord Injury. Molecular neurobiology. 2022-10-21. PMID:36269542. |
spinal cord contusion at the t10 dorsal portion was induced in mice to cause partial paralysis of the hindlimbs. |
2022-10-21 |
2023-08-14 |
mouse |
| Mariano Martini, Davide Orsin. The fight against poliomyelitis through the history: past, present and hopes for the future. Albert Sabin's missing Nobel and his "gift to all the world's children". Vaccine. 2022-10-16. PMID:36244880. |
the virus spreads from person to person and can infect a person's spinal cord, causing paralysis. |
2022-10-16 |
2023-08-14 |
Not clear |
| Christine Azevedo Coste, Lucie William, Lucas Fonseca, Arthur Hiairrassary, David Andreu, Antoine Geffrier, Jacques Teissier, Charles Fattal, David Guirau. Activating effective functional hand movements in individuals with complete tetraplegia through neural stimulation. Scientific reports. vol 12. issue 1. 2022-10-06. PMID:36202865. |
individuals with complete cervical spinal cord injury suffer from a permanent paralysis of upper limbs which prevents them from achieving most of the activities of daily living. |
2022-10-06 |
2023-08-14 |
human |
| Ruihua Fan, Lvxia Wang, Benson O A Botchway, Yong Zhang, Xuehong Li. Protective role of ethyl pyruvate in spinal cord injury by inhibiting the high mobility group box-1/toll-like receptor4/nuclear factor-kappa B signaling pathway. Frontiers in molecular neuroscience. vol 15. 2022-10-03. PMID:36187352. |
spinal cord injury (sci) is a high incident rate of central nervous system disease that usually causes paralysis below the injured level. |
2022-10-03 |
2023-08-14 |
Not clear |