| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Hou, Chaolun Liang, Lili Sui, Yang Li, Kai Wang, Xing Li, Kunrui Zheng, Haitao Su, Dianweng Xie, Dingkun Lin, Da Guo, Le Wan. Curculigoside Regulates Apoptosis and Oxidative Stress Against Spinal Cord Injury by Modulating the Nrf-2/NQO-1 Signaling Pathway In Vitro and In Vivo. Molecular neurobiology. 2024-09-04. PMID:39230866. |
spinal cord injury (sci) is a severe neurological disorder that can lead to paralysis or death. |
2024-09-04 |
2024-09-06 |
Not clear |
| Ali Shojaie, Ahmad Al Khleifat, Sarah Garrahy, Haniah Habash-Bailey, Rachel Thomson, Sarah Opie-Martin, Sara Javidnia, P Nigel Leigh, Ammar Al-Chalab. Investigating the impact of socioeconomic status on amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2024-09-01. PMID:39218010. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the gradual death of motor neurons in the brain and spinal cord, leading to fatal paralysis. |
2024-09-01 |
2024-09-04 |
human |
| Rodolfo Keesey, Ursula Hofstoetter, Zhaoshun Hu, Lorenzo Lombardi, Rachel Hawthorn, Noah Bryson, Andreas Rowald, Karen Minassian, Ismael Seáñe. FUNDAMENTAL LIMITATIONS OF KILOHERTZ-FREQUENCY CARRIERS IN AFFERENT FIBER RECRUITMENT WITH TRANSCUTANEOUS SPINAL CORD STIMULATION. bioRxiv : the preprint server for biology. 2024-08-30. PMID:39211255. |
the use of kilohertz-frequency (khf) waveforms has rapidly gained momentum in transcutaneous spinal cord stimulation (tscs) to restore motor function after paralysis. |
2024-08-30 |
2024-09-04 |
human |
| Shogo Isumi, Daiki Futamura, Takuto Hanasaki, Yukito Sako, Shotaro Miyata, Hirohito Kan, Yumika Suzuki, Naoki Hasegawa, Hajime Mushiake, Satoshi Kametaka, Yasushi Uchiyama, Makoto Osanai, Sachiko Lee-Hott. Association of medullary reticular formation ventral part with spasticity in mice suffering from photothrombotic stroke. NeuroImage. 2024-08-15. PMID:39147291. |
strokes cause spasticity via stretch reflex hyperexcitability in the spinal cord, and spastic paralysis due to involuntary muscle contraction in the hands and fingers can severely restrict skilled hand movements. |
2024-08-15 |
2024-08-18 |
mouse |
| Hao Zhong, Ke Zhang, Mi Zhou, Cong Xing, Yang An, Qi Zhang, Junrui Guo, Song Liu, Zhigang Qu, Shiqing Feng, Guangzhi Nin. An Implantable Self-Driven Diaphragm Pacing System Based on a Microvibration Triboelectric Nanogenerator for Phrenic Nerve Stimulation. ACS applied materials & interfaces. 2024-08-09. PMID:39120580. |
spinal cord injury poses considerable challenges, particularly in diaphragm paralysis. |
2024-08-09 |
2024-08-12 |
rat |
| Kai Li, Zanzhi Chen, Xuejing Chang, Ruiyang Xue, Huaibo Wang, Weitao Gu. Wnt signaling pathway in spinal cord injury: from mechanisms to potential applications. Frontiers in molecular neuroscience. vol 17. 2024-08-08. PMID:39114641. |
spinal cord injury (sci) denotes damage to both the structure and function of the spinal cord, primarily manifesting as sensory and motor deficits caused by disruptions in neural transmission pathways, potentially culminating in irreversible paralysis. |
2024-08-08 |
2024-08-10 |
Not clear |
| Penghui Li, Junlong Zhao, Yangguang Ma, Liang Wang, Shiqian Liang, Fan Fan, Tiaoxia Wei, Lei Feng, Xueyu Hu, Yiyang Hu, Zhe Wang, Hongyan Qi. Transplantation of miR-145a-5p modified M2 type microglia promotes the tissue repair of spinal cord injury in mice. Journal of translational medicine. vol 22. issue 1. 2024-08-06. PMID:39103885. |
the traumatic spinal cord injury (sci) can cause immediate multi-faceted function loss or paralysis. |
2024-08-06 |
2024-08-08 |
mouse |
| Pavlos Texakalidis, Lei Liu, Constantine L Karras, Tord D Alden, Colin K Franz, Kevin Swon. Supinator to posterior interosseous nerve transfer to restore hand opening in brachial plexus and spinal cord injury: a systematic review and individual patient-data meta-analysis. Journal of neurosurgery. Spine. 2024-08-02. PMID:39094196. |
cervical spinal cord injury (sci) and lower trunk brachial plexus injury (bpi) commonly result in hand paralysis. |
2024-08-02 |
2024-08-06 |
Not clear |
| Ridhima Vij, Hosu Kim, Hyeonggeun Park, Thanh Cheng, Djamchid Lotfi, Donna Chan. Functional recovery of a 41-year-old quadriplegic spinal cord injury patient following multiple intravenous infusions of autologous adipose-derived mesenchymal stem cells: a case report. Frontiers in transplantation. vol 2. 2024-07-12. PMID:38993875. |
spinal cord injury (sci) is a debilitating disease with clinical manifestations ranging from incomplete neurological deficits affecting sensory and motor functions to complete paralysis. |
2024-07-12 |
2024-07-14 |
Not clear |
| Venkataramanan Srinivasan, Victoria Homer, Darren Barton, Abigail Clutterbuck-James, Siân Jenkins, Claire Potter, Kristian Brock, Ann Logan, Donna Smith, Lars Bruce, Zsuzsanna Nagy, Simon P Bac. A low molecular weight dextran sulphate, ILB®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial. PloS one. vol 19. issue 7. 2024-07-11. PMID:38990927. |
it is a fatal disease with specific loss of motor neurons in the spinal cord, brain stem, and motor cortex leading to progressive paralysis and usually death within five years of diagnosis. |
2024-07-11 |
2024-07-14 |
Not clear |
| Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
| D Leonardo Garcia-Ramirez, Jenna R McGrath, Ngoc T Ha, Jaimena H Wheel, Sebastian J Atoche, Lihua Yao, Nicholas J Stachowski, Simon F Giszter, Kimberly J Doughert. Covert actions of epidural stimulation on spinal locomotor circuits. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948733. |
spinal cord injury (sci) disrupts descending controls of the spinal cord, producing paralysis. |
2024-07-01 |
2024-07-03 |
mouse |
| Evaristus C Mbanefo, Allison Seifert, Manoj Kumar Yadav, Cheng-Rong Yu, Vijayaraj Nagarajan, Ashutosh Parihar, Sunanda Singh, Charles E Egwuag. A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE). Cells. vol 13. issue 12. 2024-06-26. PMID:38920670. |
proinflammatory t-lymphocytes recruited into the brain and spinal cord mediate multiple sclerosis (ms) and currently there is no cure for ms. ifn-γ-producing th1 cells induce ascending paralysis in the spinal cord while il-17-producing th17 cells mediate cerebellar ataxia. |
2024-06-26 |
2024-06-29 |
mouse |
| Junming Fan, Xiaotong Du, Mengfan Chen, Yun Xu, Jinyu Xu, Leilei Lu, Shaoyan Zhou, Xiaoxia Kong, Ke Xu, Hongyu Zhan. Critical role of checkpoint kinase 1 in spinal cord injury-induced motor dysfunction in mice. International immunopharmacology. vol 138. 2024-06-25. PMID:38917519. |
spinal cord injury (sci) is a devastating neurotraumatic condition characterized by severe motor dysfunction and paralysis. |
2024-06-25 |
2024-06-29 |
mouse |
| Heng Zhou, Ziwei Li, Shuili Jing, Ben Wang, Zhifei Ye, Wei Xiong, Yonghao Liu, Ye Liu, Chun Xu, Tushar Kumeria, Yan He, Qingsong Y. Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatform. Journal of nanobiotechnology. vol 22. issue 1. 2024-06-21. PMID:38902789. |
spinal cord injury (sci) often results in motor and sensory deficits, or even paralysis. |
2024-06-21 |
2024-06-23 |
Not clear |
| Marvin Man Ting Chung, Gabriel Ching Ngai Leung, Wing Yuk I. Surgical Reconstruction of Elbow Extension in Spinal Cord Injury and Tetraplegia: A Systematic Review. Journal of hand surgery global online. vol 6. issue 2. 2024-06-21. PMID:38903844. |
surgical reconstruction of elbow extension can help restore function in patients with tetraplegia and triceps paralysis because of spinal cord injury. |
2024-06-21 |
2024-06-23 |
Not clear |
| Sylwia Dabrowska, Ermanna Turano, Ilaria Scambi, Federica Virla, Alice Nodari, Francesco Pezzini, Mirco Galiè, Bruno Bonetti, Raffaella Mariott. A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial Activation. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891895. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive degeneration of upper and lower motor neurons (mns) in the brain and spinal cord, leading to progressive paralysis and death. |
2024-06-19 |
2024-06-21 |
human |
| Federico Fabris, Aram Megighian, Ornella Rossetto, Morena Simonato, Giampietro Schiavo, Marco Pirazzini, Cesare Montecucc. Local tetanus begins with a VAMP cleavage-associated neuromuscular junction paralysis around the site of tetanus neurotoxin release. The American journal of pathology. 2024-06-17. PMID:38885925. |
this paralysis follows the retrograde transport of tent inside the axons of spinal cord motoneurons and its uptake by inhibitory interneurons with cleavage of vamp, a synaptic vesicle protein required for neurotransmitter release. |
2024-06-17 |
2024-06-21 |
mouse |
| J Smith Leser, Joshua L Frost, Courtney J Wilson, Michael J Rudy, Penny Clarke, Kenneth L Tyle. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. Journal of virology. 2024-06-13. PMID:38869283. |
intramuscular (im) injection of neonatal swiss webster (sw) mice with us/il/14-18952 (il52), a clinical isolate from the 2014 ev-d68 epidemic, results in many of the pathogenic features of human afm, including viral infection of the spinal cord, death of motor neurons, and resultant progressive paralysis. |
2024-06-13 |
2024-06-15 |
mouse |
| J Smith Leser, Joshua L Frost, Courtney J Wilson, Michael J Rudy, Penny Clarke, Kenneth L Tyle. VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis. Journal of virology. 2024-06-13. PMID:38869283. |
in distinction, ca/14-4231 (ca4231), another clinical isolate from the 2014 ev-d68 outbreak, does not cause paralysis in mice, does not grow in the spinal cord, and does not cause motor neuron loss following im injection. |
2024-06-13 |
2024-06-15 |
mouse |