| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunpeng Liu, Justin T Jordan, Miriam A Bredella, Serkan Erdin, James A Walker, Mark Vangel, Gordon J Harris, Scott R Plotkin, Wenli Ca. Correlation between NF1 genotype and imaging phenotype on whole-body MRI: NF1 radiogenomics. Neurology. vol 94. issue 24. 2020-09-21. PMID:32345730. |
to investigate the genotype-phenotype correlation between neurofibromatosis 1 (nf1) germline mutations and imaging features of neurofibromas on whole-body mri (wbmri) by using radiomics image analysis techniques. |
2020-09-21 |
2023-08-13 |
Not clear |
| Naomi K Atkins, J Derek Stensby, Ayman H Gaballa. Lumbosacral plexiform neurofibroma: a rare case in an adult without neurofibromatosis type I. Skeletal radiology. vol 49. issue 2. 2020-07-31. PMID:31342092. |
lumbosacral plexiform neurofibroma: a rare case in an adult without neurofibromatosis type i. plexiform neurofibromas are an uncommon variant of neurofibromas that are described as being essentially pathognomonic of neurofibromatosis type 1 (nf1). |
2020-07-31 |
2023-08-13 |
Not clear |
| Naomi K Atkins, J Derek Stensby, Ayman H Gaballa. Lumbosacral plexiform neurofibroma: a rare case in an adult without neurofibromatosis type I. Skeletal radiology. vol 49. issue 2. 2020-07-31. PMID:31342092. |
further imaging and clinical workup showed that the patient had no other identifiable neurofibromas and did not meet criteria for the diagnosis of nf1. |
2020-07-31 |
2023-08-13 |
Not clear |
| Lennart Well, Anna Jaeger, Hildegard Kehrer-Sawatzki, Said Farschtschi, Maxim Avanesov, Markus Sauer, Manuela Tavares de Sousa, Peter Bannas, Thorsten Derlin, Gerhard Adam, Victor F Mautner, Johannes M Salamo. The effect of pregnancy on growth-dynamics of neurofibromas in Neurofibromatosis type 1. PloS one. vol 15. issue 4. 2020-07-20. PMID:32343738. |
patients with neurofibromatosis type 1 (nf1) develop plexiform neurofibromas (pnf) and cutaneous neurofibromas. |
2020-07-20 |
2023-08-13 |
Not clear |
| Ciersten A Burks, Steven D Rhodes, Waylan K Bessler, Shi Chen, Abbi Smith, Jeffrey R Gehlhausen, Eric T Hawley, Li Jiang, Xiaohong Li, Jin Yuan, Qingbo Lu, Max Jacobsen, George E Sandusky, David R Jones, D Wade Clapp, Jaishri O Blakele. Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Molecular cancer therapeutics. vol 18. issue 12. 2020-07-07. PMID:31527226. |
ketotifen modulates mast cell chemotaxis to kit-ligand, but does not impact mast cell numbers, degranulation, or tumor behavior in neurofibromas of neurofibromatosis type 1 (nf1) is one of the most common genetic tumor predisposition syndromes in humans. |
2020-07-07 |
2023-08-13 |
Not clear |
| Rosalie E Ferner, Annette Bakker, Ype Elgersma, D Gareth R Evans, Marco Giovannini, Eric Legius, Alison Lloyd, Ludwine M Messiaen, Scott Plotkin, Karlyne M Reilly, Aaron Schindeler, Miriam J Smith, Nicole J Ullrich, Brigitte Widemann, Larry S Sherma. From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis. American journal of medical genetics. Part A. vol 179. issue 6. 2020-06-10. PMID:30908866. |
neurofibromatosis 1 (nf1) is common and epitomized by multiple neurofibromas with widespread complications. |
2020-06-10 |
2023-08-13 |
human |
| Roberto André Torres de Vasconcelos, Pedro Guimarães Coscarelli, Thyago Marsicano Vieira, Washington Silva Noguera, Davy Carlos Mendes Rapozo, Marcus André Aciol. Prognostic significance of mast cell and microvascular densities in malignant peripheral nerve sheath tumor with and without neurofibromatosis type 1. Cancer medicine. vol 8. issue 3. 2020-05-20. PMID:30735009. |
recently, the essential role of mast cells in the tumor onset of neurofibromatosis type 1 (nf1)-associated neurofibromas and mpnsts was confirmed in both experimental and human studies. |
2020-05-20 |
2023-08-13 |
human |
| J Salazar-Mendiguchía, C Díez-López, E Claver, S Cesar, O Campuzano, G Sarquella-Brugada, L Monserra. Familial evaluation reveals a distinct genetic cause in a large Spanish family with neurofibromatosis 1 and hypertrophic cardiomyopathy. Gene. vol 746. 2020-05-12. PMID:32283115. |
neurofibromatosis 1 (nf1) is an autosomal dominant disorder characterized by café-au-lait spots, intertriginous freckling, and multiple neurofibromas. |
2020-05-12 |
2023-08-13 |
Not clear |
| Rachel M Carnes, James A Mobley, David K Crossman, Hui Liu, Bruce R Korf, Robert A Kesterson, Deeann Walli. Multi-Omics Profiling for NF1 Target Discovery in Neurofibromin (NF1) Deficient Cells. Proteomics. vol 19. issue 11. 2020-04-28. PMID:30908848. |
in efforts to define pathways responsible for the development of neurofibromas and other cancers, transcriptomic and proteomic changes are evaluated in a non-malignant nf1 null cell line. |
2020-04-28 |
2023-08-13 |
Not clear |
| Ben Shofty, Michal Mauda-Havakuk, Liat Ben-Sira, Felix Bokstein, Zvi Lidar, Khalil Salame, Akiva Korn, Shlomi Constantin. Surgical Management of "Kissing" Spinal Plexiform Neurofibromas in Neurofibromatosis Type 1 Patients. World neurosurgery. vol 134. 2020-03-09. PMID:31786384. |
"kissing" neurofibromas (kns) are a unique group of spinal tumors found in neurofibromatosis type 1 (nf1) patients. |
2020-03-09 |
2023-08-13 |
Not clear |
| Zhiguo Chen, Juan Mo, Jean-Philippe Brosseau, Tracey Shipman, Yong Wang, Chung-Ping Liao, Jonathan M Cooper, Robert J Allaway, Sara J C Gosline, Justin Guinney, Thomas J Carroll, Lu Q L. Spatiotemporal Loss of Cancer discovery. vol 9. issue 1. 2020-03-05. PMID:30348677. |
patients with nf1 present with a wide range of clinical manifestations, and the tumor with highest prevalence is cutaneous neurofibroma (cnf). |
2020-03-05 |
2023-08-13 |
mouse |
| Jonathan S Fletcher, Jianqiang Wu, Walter J Jessen, Jay Pundavela, Jacob A Miller, Eva Dombi, Mi-Ok Kim, Tilat A Rizvi, Kashish Chetal, Nathan Salomonis, Nancy Ratne. Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice. JCI insight. vol 4. issue 3. 2020-02-25. PMID:30728335. |
we find that the chemokine cxcl10 is uniquely upregulated in nf1 mice that invariably develop neurofibroma. |
2020-02-25 |
2023-08-13 |
mouse |
| Jing Xu, Hongke Zhang, Chengbin Li, Huicong Du, Maoguo Shu, Jing Ji. Activation of PLCγ/AKT/IκBα/p65 signaling increases inflammation in mast cells to promote growth of cutaneous neurofibroma. Life sciences. vol 239. 2020-02-13. PMID:31756343. |
cutaneous neurofibroma (cnf), a hallmark feature of neurofibromatosis type 1 (nf1), results in psychological and physical damage to patients. |
2020-02-13 |
2023-08-13 |
Not clear |
| Katarina Rukavina, Rudolf Töpper, Alexandra Kunze, Alexander Hess, Markus Glatzel, Jose Manuel Valdueza, Said Farschtschi, Christian Hage. Early-onset stroke in two siblings with Neurofibromatosis type 1. European journal of medical genetics. vol 62. issue 10. 2020-02-11. PMID:31279841. |
neurofibromatosis type 1 (nf1) is an autosomal dominant neurocutaneous disorder, characterized by cafe-au-lait macules, benign neurofibromas as well as malignant peripheral nerve sheath tumours, freckling in the axillary or inguinal regions, optic glioma and lisch nodules (iris hamartomas) and further manifestations like bone deformities etc. |
2020-02-11 |
2023-08-13 |
Not clear |
| Frank L Rice, George Houk, James P Wymer, Sara J C Gosline, Justin Guinney, Jianqiang Wu, Nancy Ratner, Michael P Jankowski, Salvo La Rosa, Marilyn Dockum, James R Storey, Steven L Carroll, Phillip J Albrecht, Vincent M Riccard. The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin. PloS one. vol 14. issue 5. 2020-01-21. PMID:31107888. |
the evolution and multi-molecular properties of nf1 cutaneous neurofibromas originating from c-fiber sensory endings and terminal schwann cells at normal sites of sensory terminations in the skin. |
2020-01-21 |
2023-08-13 |
mouse |
| Frank L Rice, George Houk, James P Wymer, Sara J C Gosline, Justin Guinney, Jianqiang Wu, Nancy Ratner, Michael P Jankowski, Salvo La Rosa, Marilyn Dockum, James R Storey, Steven L Carroll, Phillip J Albrecht, Vincent M Riccard. The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin. PloS one. vol 14. issue 5. 2020-01-21. PMID:31107888. |
in addition to large plexiform neurofibromas (pnf), nf1 patients are frequently disfigured by cutaneous neurofibromas (cnf) and are often afflicted with chronic pain and itch even from seemingly normal skin areas. |
2020-01-21 |
2023-08-13 |
mouse |
| Andrew Rabley, Christopher E Bayne, Archana Shenoy, Romano T DeMarc. Genital Neurofibromatosis Presenting as Painful Clitoromegaly. Urology. vol 133. 2020-01-15. PMID:31352017. |
external genital manifestations of nf1 are rare with sporadic reports of children presenting with enlargement of their penis, clitoris, or labia due to a neurofibroma. |
2020-01-15 |
2023-08-13 |
Not clear |
| Vidhyachandra Gandhi, Pratik Gautam, Taher Chharchhodawala, Nitin Pa. Recurrent gastrointestinal bleeding in a patient with type 1 neurofibromatosis. BMJ case reports. vol 12. issue 6. 2020-01-02. PMID:31164378. |
we share our experience of an elderly man with nf1, who presented with massive recurrent gi bleeding secondary to jejunal neurofibromas. |
2020-01-02 |
2023-08-13 |
Not clear |
| Neel Malhotra, Jonathan Michael Stephen Levy, Loretta Fiorill. Topical sirolimus as an effective treatment for a deep neurofibroma in a patient with neurofibromatosis type I. Pediatric dermatology. vol 36. issue 3. 2019-12-20. PMID:30828862. |
a 14-year-old boy with neurofibromatosis type i (nf1) presented with a painful neurofibroma on his right palm. |
2019-12-20 |
2023-08-13 |
Not clear |
| Neel Malhotra, Jonathan Michael Stephen Levy, Loretta Fiorill. Topical sirolimus as an effective treatment for a deep neurofibroma in a patient with neurofibromatosis type I. Pediatric dermatology. vol 36. issue 3. 2019-12-20. PMID:30828862. |
this case demonstrates the efficacy of topical sirolimus in the management of neurofibromas in nf1. |
2019-12-20 |
2023-08-13 |
Not clear |