| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Omkar Kumar Kuwar, Nileshwar Kali. Anti-inflammatory and antioxidant effects of baicalein: targeting Nrf2, and NFĸB in neurodegenerative disease. Inflammopharmacology. 2025-02-27. PMID:40014253. |
neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, and huntington's disease, are characterized by progressive loss of neurons in the brain regions, including the hippocampus, cortex, substantia nigra, and striatum. |
2025-02-27 |
2025-03-01 |
Not clear |
| Katie Lunno. Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 1. 2025-01-03. PMID:39751165. |
we have leveraged these studies to perform large-scale epigenomic meta-analyses, reporting 220 differentially methylated loci that are altered in ad cortex, and which we are currently comparing to signatures in other neurodegenerative diseases. |
2025-01-03 |
2025-01-05 |
Not clear |
| Soumya Mukherjee, Celine Dubois, Keyla Perez, Ian Birchall, Fairlie Hinton, Catriona McLean, Colin L Masters, Blaine Russell Robert. Basic Science and Pathogenesis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 1. 2025-01-03. PMID:39751530. |
the extracellular amyloid plaques, one of the pathological hallmarks of alzheimers disease (ad), are frequently also observed in the cortex of cognitively unimpaired subjects or as co-pathology in other neurodegenerative diseases. |
2025-01-03 |
2025-01-05 |
human |
| Erika Gyenges. A tribute to Laszlo Zaborszky: pioneering discoveries in the basal forebrain and inspiring generations of neuroscientists. Brain structure & function. vol 230. issue 1. 2024-12-29. PMID:39733215. |
his findings have challenged longstanding assumptions, demonstrating that the cholinergic projections to the cortex are highly organized, with implications for neurodegenerative diseases like alzheimer's. |
2024-12-29 |
2024-12-31 |
Not clear |
| Jacques A Rousseau, Marcel Maier, Samia Ait-Mohand, Véronique Dumulon-Perreault, Otman Sarrhini, Sébastien Tremblay, Etienne Rousseau, Michael Salzmann, Brigitte Guéri. Antibody-Based PET Imaging of Misfolded Superoxide Dismutase 1 in an Amyotrophic Lateral Sclerosis Mouse Model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2024-12-12. PMID:39667814. |
amyotrophic lateral sclerosis (als) is a rare neurodegenerative disease characterized by motor neuron loss in the motor cortex, brain stem, and spinal cord. |
2024-12-12 |
2024-12-22 |
mouse |
| Song Luo, Xiaorui Wang, Bo Ma, Dongliang Liu, Li Li, Lijin Wang, Ning Ding, Liangyu Zou, Jie Wang, Jialin Pan, Daoqian Sang, Huadong Zhou, Hongdang Qu, Yi Lu, Lijuan Yan. Therapeutic potential of Simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation. Biomolecules & biomedicine. 2024-11-21. PMID:39569650. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-11-21 |
2024-11-23 |
mouse |
| Bo-Hyun Kim, Sang Won Seo, Yu Hyun Park, JiHyun Kim, Hee Jin Kim, Hyemin Jang, Jihwan Yun, Mansu Kim, Jun Pyo Ki. Clinical application of sparse canonical correlation analysis to detect genetic associations with cortical thickness in Alzheimer's disease. Frontiers in neuroscience. vol 18. 2024-10-09. PMID:39381682. |
alzheimer's disease (ad) is a progressive neurodegenerative disease characterized by cerebral cortex atrophy. |
2024-10-09 |
2024-10-11 |
Not clear |
| Chin-Feng Liu, Zong-Yang Young, Tsung-Wei Shih, Tzu-Ming Pan, Chun-Lin Le. Lactocaseibacillus-deglycosylated isoflavones prevent Aβ 40-induced Alzheimer's disease in a rat model. AMB Express. vol 14. issue 1. 2024-08-06. PMID:39105988. |
alzheimer's disease (ad) is the most common neurodegenerative disease, with symptoms appearing in the cerebral cortex and hippocampus. |
2024-08-06 |
2024-08-08 |
rat |
| Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, Giuseppe Pignatar. Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice. ACS pharmacology & translational science. vol 7. issue 7. 2024-07-18. PMID:39022351. |
the debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons (mns) in the brain, spinal cord, and motor cortex. |
2024-07-18 |
2024-07-20 |
mouse |
| Diana Wiesner, Simone Feldengut, Sarah Woelfle, Tobias M Boeckers, Albert C Ludolph, Francesco Roselli, Kelly Del Tredic. Neuropeptide FF (NPFF)-positive nerve cells of the human cerebral cortex and white matter in controls, selected neurodegenerative diseases, and schizophrenia. Acta neuropathologica communications. vol 12. issue 1. 2024-06-29. PMID:38943180. |
neuropeptide ff (npff)-positive nerve cells of the human cerebral cortex and white matter in controls, selected neurodegenerative diseases, and schizophrenia. |
2024-06-29 |
2024-07-02 |
human |
| Cara Sophie Schreiber, Ivo Wiesweg, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Berfin Schaumburg, Gülsah Gabriel, Franziska Richter, Christopher Käufe. Sex-specific biphasic alpha-synuclein response and alterations of interneurons in a COVID-19 hamster model. EBioMedicine. vol 105. 2024-06-12. PMID:38865747. |
we previously demonstrated neuroinflammation in the olfactory bulb of intranasally infected hamsters, followed by alpha-synuclein and tau accumulation in cortex, thus mirroring pathogenesis of neurodegenerative diseases such as parkinson's or alzheimer's disease. |
2024-06-12 |
2024-06-15 |
Not clear |
| Bu-Yeo Kim, Eunjin Sohn, Mee-Young Lee, Woo-Young Jeon, Kyuhyung Jo, Yu Jin Kim, Soo-Jin Jeon. Neurodegenerative pathways and metabolic changes in the hippocampus and cortex of mice exposed to urban particulate matter: Insights from an integrated interactome analysis. The Science of the total environment. 2024-06-05. PMID:38839008. |
additionally, the cortex of upm-exposed mice shows more similarities with psychiatric disorders than with neurodegenerative diseases. |
2024-06-05 |
2024-06-08 |
mouse |
| Masumi Sugiyama, Kenneth S Kosik, Eleni Panagioto. Mathematical topology and geometry-based classification of tauopathies. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555402. |
neurodegenerative diseases, like alzheimer's, are associated with the presence of neurofibrillary lesions formed by tau protein filaments in the cerebral cortex. |
2024-03-30 |
2024-04-02 |
Not clear |
| LiJun Zhou, RenShi X. Invertebrate genetic models of amyotrophic lateral sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-03-19. PMID:38500677. |
amyotrophic lateral sclerosis (als) is a common adult-onset neurodegenerative disease characterized by the progressive death of motor neurons in the cerebral cortex, brain stem, and spinal cord. |
2024-03-19 |
2024-03-21 |
human |
| Jelena Scekic-Zahirovic, Cristina Benetton, Aurore Brunet, XiaoQian Ye, Evgeny Logunov, Vincent Douchamps, Salim Megat, Virginie Andry, Vanessa Wing Yin Kan, Geoffrey Stuart-Lopez, Johan Gilet, Simon J Guillot, Sylvie Dirrig-Grosch, Charlotte Gorin, Margaux Trombini, Stéphane Dieterle, Jérôme Sinniger, Mathieu Fischer, Frédérique René, Zeynep Gunes, Pascal Kessler, Luc Dupuis, Pierre-François Pradat, Yannick Goumon, Romain Goutagny, Véronique Marchand-Pauvert, Sabine Liebscher, Caroline Rouau. Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency. Science translational medicine. vol 16. issue 738. 2024-03-13. PMID:38478631. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease, characterized by the death of upper (umn) and lower motor neurons (lmn) in the motor cortex, brainstem, and spinal cord. |
2024-03-13 |
2024-03-16 |
mouse |
| Aleksandra Opęchowska, Kacper Karpiuk, Andrii Zahorodnii, Ewa Harasim-Symbor, Adrian Chabowski, Karolina Konstantynowicz-Nowick. Anti-inflammatory effects of cannabidiol in early stages of neuroinflammation induced by high-fat diet in cerebral cortex of rats. Toxicology and applied pharmacology. 2024-02-09. PMID:38336253. |
our results strongly suggest the ability of cbd to reduce the formation of lipid inflammation precursors in rat cerebral cortex, as a primary event in the development of neurodegenerative diseases. |
2024-02-09 |
2024-02-12 |
rat |
| Sara Costa-Pinto, Joana Gonçalves-Ribeiro, Joana Tedim-Moreira, Renato Socodato, João B Relvas, Ana M Sebastião, Sandra H Va. Communication defects with astroglia contribute to early impairments in the motor cortex plasticity of SOD1 Neurobiology of disease. 2024-02-09. PMID:38336279. |
communication defects with astroglia contribute to early impairments in the motor cortex plasticity of sod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease, involving the selective degeneration of cortical upper synapses in the primary motor cortex (m1). |
2024-02-09 |
2024-02-12 |
Not clear |
| Patrizia Ratano, Germana Cocozza, Cecilia Pinchera, Ludovica Maria Busdraghi, Iva Cantando, Katiuscia Martinello, Mariarosaria Scioli, Maria Rosito, Paola Bezzi, Sergio Fucile, Heike Wulff, Cristina Limatola, Giuseppina D'Alessandr. Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3. Frontiers in molecular neuroscience. vol 16. 2024-01-31. PMID:38292023. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with no effective therapy, causing progressive loss of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-01-31 |
2024-02-02 |
mouse |
| Jian Lu, An-Xu He, Zhuo-Ying Jin, Meng Zhang, Zhong-Xin Li, Fan Zhou, Lin Ma, Hong-Ming Jin, Jia-Ying Wang, Xu She. Desloratadine alleviates ALS-like pathology in hSOD1 Acta pharmacologica Sinica. 2024-01-29. PMID:38286832. |
desloratadine alleviates als-like pathology in hsod1 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with progressive loss of motor neurons in the spinal cord, cerebral cortex and brain stem. |
2024-01-29 |
2024-02-01 |
Not clear |
| Samuel Lundt, Nannan Zhang, Luis Polo-Parada, Xinglong Wang, Shinghua Din. Dietary NMN supplementation enhances motor and NMJ function in ALS. Experimental neurology. 2024-01-24. PMID:38266764. |
amyotrophic lateral sclerosis (als) is an adult-onset neurodegenerative disease that causes the degeneration of motor neurons in the motor cortex and spinal cord. |
2024-01-24 |
2024-01-27 |
Not clear |