All Relations between Neurodegenerative Diseases and cerebral cortex

Publication Sentence Publish Date Extraction Date Species
Masumi Sugiyama, Kenneth S Kosik, Eleni Panagioto. Mathematical topology and geometry-based classification of tauopathies. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555402. neurodegenerative diseases, like alzheimer's, are associated with the presence of neurofibrillary lesions formed by tau protein filaments in the cerebral cortex. 2024-03-30 2024-04-02 Not clear
LiJun Zhou, RenShi X. Invertebrate genetic models of amyotrophic lateral sclerosis. Frontiers in molecular neuroscience. vol 17. 2024-03-19. PMID:38500677. amyotrophic lateral sclerosis (als) is a common adult-onset neurodegenerative disease characterized by the progressive death of motor neurons in the cerebral cortex, brain stem, and spinal cord. 2024-03-19 2024-03-21 human
Jelena Scekic-Zahirovic, Cristina Benetton, Aurore Brunet, XiaoQian Ye, Evgeny Logunov, Vincent Douchamps, Salim Megat, Virginie Andry, Vanessa Wing Yin Kan, Geoffrey Stuart-Lopez, Johan Gilet, Simon J Guillot, Sylvie Dirrig-Grosch, Charlotte Gorin, Margaux Trombini, Stéphane Dieterle, Jérôme Sinniger, Mathieu Fischer, Frédérique René, Zeynep Gunes, Pascal Kessler, Luc Dupuis, Pierre-François Pradat, Yannick Goumon, Romain Goutagny, Véronique Marchand-Pauvert, Sabine Liebscher, Caroline Rouau. Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency. Science translational medicine. vol 16. issue 738. 2024-03-13. PMID:38478631. amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease, characterized by the death of upper (umn) and lower motor neurons (lmn) in the motor cortex, brainstem, and spinal cord. 2024-03-13 2024-03-16 mouse
Aleksandra Opęchowska, Kacper Karpiuk, Andrii Zahorodnii, Ewa Harasim-Symbor, Adrian Chabowski, Karolina Konstantynowicz-Nowick. Anti-inflammatory effects of cannabidiol in early stages of neuroinflammation induced by high-fat diet in cerebral cortex of rats. Toxicology and applied pharmacology. 2024-02-09. PMID:38336253. our results strongly suggest the ability of cbd to reduce the formation of lipid inflammation precursors in rat cerebral cortex, as a primary event in the development of neurodegenerative diseases. 2024-02-09 2024-02-12 rat
Sara Costa-Pinto, Joana Gonçalves-Ribeiro, Joana Tedim-Moreira, Renato Socodato, João B Relvas, Ana M Sebastião, Sandra H Va. Communication defects with astroglia contribute to early impairments in the motor cortex plasticity of SOD1 Neurobiology of disease. 2024-02-09. PMID:38336279. communication defects with astroglia contribute to early impairments in the motor cortex plasticity of sod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease, involving the selective degeneration of cortical upper synapses in the primary motor cortex (m1). 2024-02-09 2024-02-12 Not clear
Patrizia Ratano, Germana Cocozza, Cecilia Pinchera, Ludovica Maria Busdraghi, Iva Cantando, Katiuscia Martinello, Mariarosaria Scioli, Maria Rosito, Paola Bezzi, Sergio Fucile, Heike Wulff, Cristina Limatola, Giuseppina D'Alessandr. Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3. Frontiers in molecular neuroscience. vol 16. 2024-01-31. PMID:38292023. amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with no effective therapy, causing progressive loss of motor neurons in the spinal cord, brainstem, and motor cortex. 2024-01-31 2024-02-02 mouse
Jian Lu, An-Xu He, Zhuo-Ying Jin, Meng Zhang, Zhong-Xin Li, Fan Zhou, Lin Ma, Hong-Ming Jin, Jia-Ying Wang, Xu She. Desloratadine alleviates ALS-like pathology in hSOD1 Acta pharmacologica Sinica. 2024-01-29. PMID:38286832. desloratadine alleviates als-like pathology in hsod1 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease with progressive loss of motor neurons in the spinal cord, cerebral cortex and brain stem. 2024-01-29 2024-02-01 Not clear
Samuel Lundt, Nannan Zhang, Luis Polo-Parada, Xinglong Wang, Shinghua Din. Dietary NMN supplementation enhances motor and NMJ function in ALS. Experimental neurology. 2024-01-24. PMID:38266764. amyotrophic lateral sclerosis (als) is an adult-onset neurodegenerative disease that causes the degeneration of motor neurons in the motor cortex and spinal cord. 2024-01-24 2024-01-27 Not clear
Mala R Ananth, John D Gardus, Chuan Huang, Nikhil Palekar, Mark Slifstein, Laszlo Zaborszky, Ramin V Parsey, David A Talmage, Christine DeLorenzo, Lorna W Rol. Loss of septal cholinergic input to lateral entorhinal cortex is an early indicator of cognitive impairment. Research square. 2024-01-23. PMID:38260541. we focus on the cholinergic innervation of the entorhinal cortex (ec), a region that is recognized to be susceptible early in aging and neurodegenerative disease. 2024-01-23 2024-01-25 mouse
Rachel Waller, Joanna J Bury, Charlie Appleby-Mallinder, Matthew Wyles, George Loxley, Aditi Babel, Saleh Shekari, Mbombe Kazoka, Helen Wollff, Ammar Al-Chalabi, Paul R Heath, Pamela J Shaw, Janine Kirb. Establishing mRNA and microRNA interactions driving disease heterogeneity in amyotrophic lateral sclerosis patient survival. Brain communications. vol 6. issue 1. 2024-01-01. PMID:38162899. amyotrophic lateral sclerosis is a fatal neurodegenerative disease, associated with the degeneration of both upper and lower motor neurons of the motor cortex, brainstem and spinal cord. 2024-01-01 2024-01-05 Not clear
Justin L Bollinger, Matthew J Horchar, Eric S Wohle. Repeated activation of pyramidal neurons in the prefrontal cortex alters microglial phenotype in male mice. The Journal of pharmacology and experimental therapeutics. 2023-12-21. PMID:38129124. aberrant neuronal activity in the cortex alters microglia phenotype and function in several contexts, including chronic psychological stress and neurodegenerative disease. 2023-12-21 2023-12-24 mouse
Shani Blumenreich, Doreen Padan Ben-Yashar, Tali Shalit, Meital Kupervaser, Ivan Milenkovic, Tammar Joseph, Anthony H Futerma. Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1. Journal of neurochemistry. 2023-12-10. PMID:38071490. one protein, transglutaminase 1 (tgm1), which is elevated in a number of neurodegenerative diseases, was absent from the control group but was found at high levels in cbe-injected mice, and located in the extracellular matrix (ecm) in layer v of the cortex and intracellularly in purkinje cells in the cerebellum. 2023-12-10 2023-12-17 mouse
Haiyang Ma, Jia Huo, Cheng Xin, Jing Yang, Qi Liu, Hui Dong, Rui Li, Yaling Li. RABGGTB plays a critical role in ALS pathogenesis. Brain research bulletin. 2023-12-02. PMID:38042502. amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease with unknown causes, which mainly affects motor neurons in the anterior horn of the spinal cord, brain stem, and cerebral cortex, also known as motor neuron disease. 2023-12-02 2023-12-10 Not clear
Lijun Zhou, Wenzhi Chen, Shishi Jiang, Renshi X. In Vitro Models of Amyotrophic Lateral Sclerosis. Cellular and molecular neurobiology. 2023-10-23. PMID:37870685. amyotrophic lateral sclerosis (als) is one of the commonest neurodegenerative diseases of adult-onset, which is characterized by the progressive death of motor neurons in the cerebral cortex, brain stem and spinal cord. 2023-10-23 2023-11-08 Not clear
Hilary Piercy, Charlotte Nuttin. The experiences of parents of children diagnosed with cerebral adrenoleukodystrophy. Child: care, health and development. 2023-10-18. PMID:37850425. adrenoleukodystrophy (ald) is a rare x-linked neurodegenerative disease, affecting the brain, spinal cord and adrenal cortex. 2023-10-18 2023-11-08 Not clear
Rashmi Gamage, Ilaria Rossetti, Garry Niedermayer, Gerald Münch, Yossi Buskila, Erika Gyenges. Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum. Journal of neuroinflammation. vol 20. issue 1. 2023-10-14. PMID:37833764. the basal forebrain cholinergic neurons (bfcn) provide the primary source of cholinergic innervation of the human cerebral cortex and may be differentially vulnerable in various neurodegenerative diseases. 2023-10-14 2023-10-15 mouse
Serenella Anzilotti, Valeria Valente, Paola Brancaccio, Cristina Franco, Antonella Casamassa, Giovanna Lombardi, Alessandra Palazzi, Andrea Conte, Simona Paladino, Lorella Maria Teresa Canzoniero, Lucio Annunziato, Giovanna Maria Pierantoni, Giuseppe Pignatar. Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 167. 2023-09-20. PMID:37729728. amyotrophic lateral sclerosis (als) is a progressive and often fatal neurodegenerative disease characterized by the loss of motor neurons (mns) in spinal cord, motor cortex and brainstem. 2023-09-20 2023-10-07 mouse
Megan F Duffy, Jinhui Ding, Rebekah G Langston, Syed I Shah, Mike A Nalls, Sonja W Scholz, D Thad Whitaker, Pavan K Auluck, Stefano Marenco, J Raphael Gibbs, Mark R Cookso. Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease. bioRxiv : the preprint server for biology. 2023-08-14. PMID:37577533. we sampled 155,192 nuclei from two cortical regions (entorhinal cortex and middle temporal gyrus) and two subcortical regions (putamen and subventricular zone) relevant to neurodegenerative diseases or the proliferative niche. 2023-08-14 2023-08-16 human
Laura López-Pingarrón, Henrique Almeida, Marisol Soria-Aznar, Marcos C Reyes-Gonzales, María Pilar Terrón, Joaquín J Garcí. Role of Oxidative Stress on the Etiology and Pathophysiology of Amyotrophic Lateral Sclerosis (ALS) and Its Relation with the Enteric Nervous System. Current issues in molecular biology. vol 45. issue 4. 2023-05-16. PMID:37185741. amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease affecting motor neurons in the spinal cord, cerebral cortex, and medulla oblongata. 2023-05-16 2023-08-14 Not clear
Jibo Wang, Haowen Qiao, Zhenyan Wang, Wen Zhao, Tao Chen, Bin Li, Lili Zhu, Sihan Chen, Longjun Gu, Ying Wu, Zhentao Zhang, Linlin Bi, Pu Che. Rationally Design and Acoustically Assemble Human Cerebral Cortex-like Microtissues from hiPSC-derived Neural Progenitors and Neurons. Advanced materials (Deerfield Beach, Fla.). 2023-05-12. PMID:37170683. overall, we provided a high-fidelity human-relevant in vitro histotypic models for cerebral cortex, and these models will facilitate wide applications in probing the mechanisms of neurodegenerative diseases and screening the candidates of neuroprotective agents. 2023-05-12 2023-08-14 human