| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minjing Ke, Cheong-Meng Chong, Qi Zhu, Ke Zhang, Cui-Zan Cai, Jia-Hong Lu, Dajiang Qin, Huanxing S. Comprehensive Perspectives on Experimental Models for Parkinson's Disease. Aging and disease. vol 12. issue 1. 2021-02-06. PMID:33532138. |
parkinson's disease (pd) ranks second among the most common neurodegenerative diseases, characterized by progressive and selective loss of dopaminergic neurons. |
2021-02-06 |
2023-08-13 |
Not clear |
| Kecheng Lei, Yijue Shen, Yijing He, Liwen Zhang, Jingxing Zhang, Weifang Tong, Yichun Xu, Lingjing Ji. Baicalin Represses C/EBP Oxidative medicine and cellular longevity. vol 2020. 2021-01-27. PMID:32566108. |
baicalin represses c/ebp parkinson's disease (pd) is a neurodegenerative disease characterized by the gradual loss of dopaminergic (da) neurons in the substantia nigra (sn) and the formation of intracellular lewy bodies (lb) in the brain, which aggregates |
2021-01-27 |
2023-08-13 |
Not clear |
| Mohammad Najim Uddin, Mohammad Injamul Hoq, Israt Jahan, Shafayet Ahmed Siddiqui, Chayan Dhar Clinton, Mohammed Ibrahim, Mohammad Safiqul Islam, Md Jakari. The mechanistic role of thymoquinone in Parkinson's disease: focus on neuroprotection in pre-clinical studies. Current molecular pharmacology. 2021-01-06. PMID:33402092. |
parkinson's disease (pd) is a long-term neurodegenerative disease with movement difficulties, and the common feature of neurodegeneration in pd patients is caused by dopaminergic neural damage in the substantia nigra pars compacta. |
2021-01-06 |
2023-08-13 |
Not clear |
| Qi-Wen Han, Yu-He Yuan, Nai-Hong Che. The therapeutic role of cannabinoid receptors and its agonists or antagonists in Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31442553. |
parkinson's disease (pd) is a neurodegenerative disease and its characteristic is the progressive degeneration of dopaminergic neurons within the substantia nigra (sn) of the midbrain. |
2021-01-04 |
2023-08-13 |
Not clear |
| Shelby L Johnson, Jaclyn Iannucci, Navindra P Seeram, Paula Gramma. Inhibiting thrombin improves motor function and decreases oxidative stress in the LRRK2 transgenic Drosophila melanogaster model of Parkinson's disease. Biochemical and biophysical research communications. vol 527. issue 2. 2021-01-04. PMID:32423817. |
parkinson's disease (pd) is a complex neurodegenerative disease characterized by the presence of tremors, loss of dopaminergic neurons and accumulation of α-synuclein. |
2021-01-04 |
2023-08-13 |
drosophila_melanogaster |
| Nikita Katila, Sunil Bhurtel, Pil-Hoon Park, Jin Tae Hong, Dong-Young Cho. Activation of AMPK/aPKCζ/CREB pathway by metformin is associated with upregulation of GDNF and dopamine. Biochemical pharmacology. vol 180. 2020-12-31. PMID:32800853. |
parkinson's disease (pd) is the second most common neurodegenerative disease, which is characterized by the progressive loss of dopaminergic neurons in the substantia nigra, leading to a decrease in striatal dopamine. |
2020-12-31 |
2023-08-13 |
mouse |
| Claudio Giuliano, Francesca Siani, Liudmila Mus, Cristina Ghezzi, Silvia Cerri, Barbara Pacchetti, Chiara Bigogno, Fabio Blandin. Neuroprotective effects of lignan 7-hydroxymatairesinol (HMR/lignan) in a rodent model of Parkinson's disease. Nutrition (Burbank, Los Angeles County, Calif.). vol 69. 2020-12-23. PMID:31586482. |
parkinson's disease (pd) is a neurodegenerative disease characterized by loss of dopaminergic neurons in the substantia nigra pars compacta (snc). |
2020-12-23 |
2023-08-13 |
rat |
| Irving Parra, Isabel Martínez, Gabriel Ramírez-García, Yousef Tizabi, Liliana Mendiet. Differential Effects of LPS and 6-OHDA on Microglia's Morphology in Rats: Implications for Inflammatory Model of Parkinson's Disease. Neurotoxicity research. vol 37. issue 1. 2020-12-21. PMID:31478124. |
parkinson's disease (pd) is an idiopathic and progressive neurodegenerative disease characterized by the loss of ~ 80% of dopaminergic neurons in substantia nigra pars compacta (snpc). |
2020-12-21 |
2023-08-13 |
rat |
| Ji Wang, Fushun Wang, Dongmei Mai, Shaogang Q. Molecular Mechanisms of Glutamate Toxicity in Parkinson's Disease. Frontiers in neuroscience. vol 14. 2020-12-17. PMID:33324150. |
parkinson's disease (pd) is a common neurodegenerative disease, the pathological features of which include the presence of lewy bodies and the neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta. |
2020-12-17 |
2023-08-13 |
Not clear |
| Chao-Qun Lin, Lu-Kui Che. Cerebral dopamine neurotrophic factor promotes the proliferation and differentiation of neural stem cells in hypoxic environments. Neural regeneration research. vol 15. issue 11. 2020-12-11. PMID:32394962. |
previous research found that cerebral dopamine neurotrophic factor (cdnf) has a protective effect on brain dopaminergic neurons, and cdnf is regarded as a promising therapeutic agent for neurodegenerative diseases. |
2020-12-11 |
2023-08-13 |
rat |
| N V Katolikova, A B Malashicheva, R R Gainetdino. [Cell Replacement Therapy in Parkinson's Disease-History of Development and Prospects for Use in Clinical Practice]. Molekuliarnaia biologiia. vol 54. issue 6. 2020-12-09. PMID:33276357. |
parkinson's disease is a widespread neurodegenerative disease, which is characterized by the death of dopaminergic neurons in the substantia nigra of the midbrain. |
2020-12-09 |
2023-08-13 |
Not clear |
| Kyle Farmer, Khaled S Abd-Elrahman, Alexa Derksen, Elyn M Rowe, Ashley M Thompson, Christopher A Rudyk, Natalie A Prowse, Zachary Dwyer, Samantha C Bureau, Teresa Fortin, Stephen S G Ferguson, Shawn Hayle. mGluR5 Allosteric Modulation Promotes Neurorecovery in a 6-OHDA-Toxicant Model of Parkinson's Disease. Molecular neurobiology. vol 57. issue 3. 2020-12-04. PMID:31754998. |
parkinson's disease is a neurodegenerative disease characterized by a loss of dopaminergic substantia nigra neurons and depletion of dopamine. |
2020-12-04 |
2023-08-13 |
mouse |
| Rasool Haddadi, Zahra Shahidi, Shahla Eyvari-Brooshghala. Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 79. 2020-11-30. PMID:32920285. |
parkinson's disease is a progressive neurodegenerative disease characterized by the dramatic death of dopaminergic neuronal cells, especially in the snc and caused alpha-synuclein accumulation in the neurons. |
2020-11-30 |
2023-08-13 |
Not clear |
| Yan Yang, Fancong Kong, Qingqing Ding, Ying Cai, Yanlei Hao, Beisha Tan. Bruceine D elevates Nrf2 activation to restrain Parkinson's disease in mice through suppressing oxidative stress and inflammatory response. Biochemical and biophysical research communications. vol 526. issue 4. 2020-11-25. PMID:32321640. |
parkinson's disease (pd) is neurodegenerative disease, featured by a loss of dopaminergic neurons in the substantia nigra pars compacta (snpc), characteristic motor symptoms and cognitive impairment. |
2020-11-25 |
2023-08-13 |
mouse |
| Hikmat Hadoush, Tamara Lababneh, Saleem A Banihani, Muhammed Al-Jarrah, Mohammed Jamou. Melatonin and dopamine serum level associations with motor, cognitive, and sleep dysfunctions in patients with Parkinson's disease: A cross-sectional research study. NeuroRehabilitation. vol 46. issue 4. 2020-11-20. PMID:32538881. |
parkinson's disease (pd) is a multisystem-progressive neurodegenerative disease characterized by dopaminergic neurons, however, the role of the non-dopaminergic system (such as melatonin hormone) in the pathogenesis of pd is now emerging. |
2020-11-20 |
2023-08-13 |
Not clear |
| Yu-Ling Liu, Chia-Chi Hsu, Hui-Ju Huang, Chih-Jung Chang, Shu-Hui Sun, Anya Maan-Yuh Li. Gallic Acid Attenuated LPS-Induced Neuroinflammation: Protein Aggregation and Necroptosis. Molecular neurobiology. vol 57. issue 1. 2020-11-19. PMID:31832973. |
furthermore, ga prevented lps-induced programmed cell deaths of nigrostriatal dopaminergic neurons of the rat brain, suggesting that ga may be neuroprotective by attenuating neuroinflammation in cns neurodegenerative diseases. |
2020-11-19 |
2023-08-13 |
rat |
| Xinyao Liu, Weidong L. Profiling Non-motor Symptoms in Monogenic Parkinson's Disease. Frontiers in aging neuroscience. vol 12. 2020-11-17. PMID:33192488. |
parkinson's disease (pd) is the second most common neurodegenerative disease in the elder population, pathologically characterized by the progressive loss of dopaminergic neurons in the substantia nigra. |
2020-11-17 |
2023-08-13 |
Not clear |
| Jeffrey Kim, Marcel M Daad. Non-cell autonomous mechanism of Parkinson's disease pathology caused by G2019S LRRK2 mutation in Ashkenazi Jewish patient: Single cell analysis. Brain research. vol 1722. 2020-10-21. PMID:31330122. |
parkinson's disease (pd) is the second most prevalent neurodegenerative disease, characterized by the loss of the midbrain dopaminergic neurons, which leads to impaired motor and cognitive functions. |
2020-10-21 |
2023-08-13 |
Not clear |
| Takuya Uehara, Chi-Jing Choong, Masayuki Nakamori, Hideki Hayakawa, Kumiko Nishiyama, Yuuya Kasahara, Kousuke Baba, Tetsuya Nagata, Takanori Yokota, Hiroshi Tsuda, Satoshi Obika, Hideki Mochizuk. Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease. Scientific reports. vol 9. issue 1. 2020-10-14. PMID:31110191. |
parkinson's disease (pd) is a neurodegenerative disease caused by the loss of dopaminergic neurons in the substantia nigra. |
2020-10-14 |
2023-08-13 |
mouse |
| Jingya Zhao, Hongli Li, Na Chan. LncRNA HOTAIR promotes MPP+-induced neuronal injury in Parkinson's disease by regulating the miR-874-5p/ATG10 axis. EXCLI journal. vol 19. 2020-10-06. PMID:33013268. |
parkinson's disease (pd) is a neurodegenerative disease caused by the loss of dopaminergic neurons. |
2020-10-06 |
2023-08-13 |
Not clear |