| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yadan Zhao, Zichen Zhang, Siru Qin, Wen Fan, Wei Li, Jingyi Liu, Songtao Wang, Zhifang Xu, Meidan Zha. Acupuncture for Parkinson's Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit. Neural plasticity. vol 2021. 2021-07-29. PMID:34221005. |
parkinson's disease (pd) is a chronic and progressive neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra. |
2021-07-29 |
2023-08-13 |
Not clear |
| Zihua Liu, Qiang Ye, Fang Wang, Yanan Guo, Rong Cui, Jianlin Wang, Degui Wan. Overexpression of thioredoxin reductase 1 can reduce DNA damage, mitochondrial autophagy and endoplasmic reticulum stress in Parkinson's disease. Experimental brain research. vol 239. issue 2. 2021-07-28. PMID:33230666. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (sn). |
2021-07-28 |
2023-08-13 |
mouse |
| Hexin Yan, Hui Zhao, Yunxiao Kang, Xiaoming Ji, Tianyun Zhang, Yu Wang, Rui Cui, Guoliang Zhang, Geming Sh. Parecoxib alleviates the motor behavioral decline of aged rats by ameliorating mitochondrial dysfunction in the substantia nigra via COX-2/PGE2 pathway inhibition. Neuropharmacology. vol 194. 2021-07-28. PMID:34089729. |
cyclooxygenase 2 (cox-2), the rate-limiting enzyme in the prostaglandin e2 (pge2) synthesis pathway, is implicated in aging and age-related neurodegenerative diseases; moreover, inhibition of cox-2 expression has been shown to be neuroprotective for nigrostriatal dopaminergic neurons. |
2021-07-28 |
2023-08-13 |
rat |
| Giulia Gaggi, Andrea Di Credico, Pascal Izzicupo, Giovanni Iannetti, Angela Di Baldassarre, Barbara Ghinass. Chemical and Biological Molecules Involved in Differentiation, Maturation, and Survival of Dopaminergic Neurons in Health and Parkinson's Disease: Physiological Aspects and Clinical Implications. Biomedicines. vol 9. issue 7. 2021-07-27. PMID:34209807. |
parkinson's disease (pd) is one of the most common neurodegenerative disease characterized by a specific and progressive loss of dopaminergic (da) neurons and dopamine, causing motor dysfunctions and impaired movements. |
2021-07-27 |
2023-08-13 |
human |
| Mangala Kumari, Premdass Ramdas, Ammu Kutty Radhakrishnan, Methil Kannan Kutty, Nagaraja Haleagrahar. Tocotrienols Ameliorate Neurodegeneration and Motor Deficits in the 6-OHDA-Induced Rat Model of Parkinsonism: Behavioural and Immunohistochemistry Analysis. Nutrients. vol 13. issue 5. 2021-07-26. PMID:34068460. |
parkinson's disease (pd) is a debilitating neurodegenerative disease, which progresses over time, causing pathological depigmentation of the substantia nigra (sn) in the midbrain due to loss of dopaminergic neurons. |
2021-07-26 |
2023-08-13 |
rat |
| Debapriya Garabadu, Nidhi Agrawa. Naringin Exhibits Neuroprotection Against Rotenone-Induced Neurotoxicity in Experimental Rodents. Neuromolecular medicine. vol 22. issue 2. 2021-07-19. PMID:31916219. |
parkinson's disease (pd) is a neurodegenerative disease that is accompanied with the loss of dopaminergic neurons in the substantia nigra pars compacta which subsequently leads to a reduction in the dopamine level in the striatum. |
2021-07-19 |
2023-08-13 |
rat |
| Viktoria C Ruf, Song Shi, Felix Schmidt, Daniel Weckbecker, Georg S Nübling, Uwe Ködel, Brit Mollenhauer, Armin Gies. Potential sources of interference with the highly sensitive detection and quantification of alpha-synuclein seeds by qRT-QuIC. FEBS open bio. vol 10. issue 5. 2021-07-09. PMID:32190992. |
parkinson's disease (pd) is a progressive neurodegenerative disease which is histologically characterized by loss of dopaminergic neurons in the substantia nigra and deposition of aggregated alpha-synuclein (asyn) in the brain. |
2021-07-09 |
2023-08-13 |
Not clear |
| Zhuangzhuang Xiao, Tong Lei, Yanyan Liu, Yanjie Yang, Wangyu Bi, Hongwu D. The potential therapy with dental tissue-derived mesenchymal stem cells in Parkinson's disease. Stem cell research & therapy. vol 12. issue 1. 2021-07-05. PMID:33407864. |
parkinson's disease (pd), the second most common neurodegenerative disease worldwide, is caused by the loss of dopaminergic (daergic) neurons in the substantia nigra resulting in a series of motor or non-motor disorders. |
2021-07-05 |
2023-08-13 |
human |
| Fatih Soke, Bilge Kocer, Isil Fidan, Pembe Keskinoglu, Arzu Guclu-Gundu. Effects of task-oriented training combined with aerobic training on serum BDNF, GDNF, IGF-1, VEGF, TNF-α, and IL-1β levels in people with Parkinson's disease: A randomized controlled study. Experimental gerontology. vol 150. 2021-07-02. PMID:33965556. |
parkinson's disease (pd) is a chronic neurodegenerative disease characterized by the death of dopaminergic neurons in the substantia nigra pars compacta. |
2021-07-02 |
2023-08-13 |
Not clear |
| Khadga Raj, G D Gupta, Shamsher Sing. l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson's disease. Drug and chemical toxicology. 2021-07-02. PMID:34210222. |
parkinson's disease (pd) is the second most prevalent progressive neurodegenerative disease, characterized by loss of dopaminergic neurons in substantia nigra, with deficiency of dopamine in the striatum. |
2021-07-02 |
2023-08-13 |
rat |
| Yuki Kitamura, Mayuko Sakanashi, Azuki Ozawa, Yuri Saeki, Ayano Nakamura, Yuiho Hara, Ken-Ichi Saeki, Sakae Arimoto-Kobayash. Protective effect of Actinidia arguta in MPTP-induced Parkinson's disease model mice. Biochemical and biophysical research communications. vol 555. 2021-06-30. PMID:33819745. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra. |
2021-06-30 |
2023-08-13 |
mouse |
| Emily E Noble, Christine A Olson, Elizabeth Davis, Linda Tsan, Yen-Wei Chen, Ruth Schade, Clarissa Liu, Andrea Suarez, Roshonda B Jones, Claire de La Serre, Xia Yang, Elaine Y Hsiao, Scott E Kanosk. Gut microbial taxa elevated by dietary sugar disrupt memory function. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33790226. |
hippocampus transcriptome analyses revealed that early life sugar consumption altered gene expression in intracellular kinase and synaptic neurotransmitter signaling pathways, whereas parabacteroides microbial enrichment altered gene expression in pathways associated with metabolic function, neurodegenerative disease, and dopaminergic signaling. |
2021-06-28 |
2023-08-13 |
rat |
| Qiankun Lv, Zhen Zhong, Binbin Hu, Si Yan, Yufang Yan, Junjun Zhang, Ting Shi, Lijuan Jiang, Wen Li, Wei Huan. MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease. Journal of neurochemistry. vol 157. issue 3. 2021-06-21. PMID:33448372. |
parkinson disease (pd) is a neurodegenerative disease characterized by selective loss of dopaminergic (da) neurons in the midbrain. |
2021-06-21 |
2023-08-13 |
mouse |
| Marie-Amandine Bonte, Fatima El Idrissi, Bernard Gressier, David Devos, Karim Belarb. Protein network exploration prioritizes targets for modulating neuroinflammation in Parkinson's disease. International immunopharmacology. vol 95. 2021-06-15. PMID:33756233. |
parkinson's disease is a progressive neurodegenerative disease associated with a loss of dopaminergic neurons in the substantia nigra of the brain. |
2021-06-15 |
2023-08-13 |
Not clear |
| T Celeste Napier, Alana Kirby, Amanda L Person. The role of dopamine pharmacotherapy and addiction-like behaviors in Parkinson's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 102. 2021-06-07. PMID:32272129. |
pd is a progressive neurodegenerative disease that involves a gradual loss of dopaminergic neurons largely within nigrostriatal projections. |
2021-06-07 |
2023-08-13 |
rat |
| Ashish Singh, Pratibha Tripathi, Arun Kumar Yadawa, Sarika Sing. Promising Polyphenols in Parkinson's Disease Therapeutics. Neurochemical research. vol 45. issue 8. 2021-06-03. PMID:32462543. |
parkinson's disease (pd) is a slow progressive, second most common neurodegenerative disease characterized by the loss of dopaminergic neurons from the nigrostriatal pathway. |
2021-06-03 |
2023-08-13 |
Not clear |
| Liesbeth Reneman, Marieke van der Pluijm, Anouk Schrantee, Elsmarieke van de Giesse. Imaging of the dopamine system with focus on pharmacological MRI and neuromelanin imaging. European journal of radiology. vol 140. 2021-06-02. PMID:34004428. |
both techniques are still primarily used in clinical research, but there is promise for clinical application, in particular for nm-mri in dopaminergic neurodegenerative diseases like parkinson's disease. |
2021-06-02 |
2023-08-13 |
Not clear |
| Mahalaxmi Iyer, Mohana Devi Subramaniam, Dhivya Venkatesan, Ssang-Goo Cho, Matias Ryding, Morten Meyer, Balachandar Vellingir. Role of RhoA-ROCK signaling in Parkinson's disease. European journal of pharmacology. vol 894. 2021-05-28. PMID:33345850. |
parkinson's disease (pd) is a complex and widespread neurodegenerative disease characterized by depletion of midbrain dopaminergic (da) neurons. |
2021-05-28 |
2023-08-13 |
Not clear |
| Hyongjun Jeon, Chang-Hwan Bae, Yukyoung Lee, Hee-Young Kim, Seungtae Ki. Korean red ginseng suppresses 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced inflammation in the substantia nigra and colon. Brain, behavior, and immunity. vol 94. 2021-05-28. PMID:33662500. |
parkinson's disease (pd) is a neurodegenerative disease involving dopaminergic neuronal death in the substantia nigra (sn); recent studies have shown that interactions between gut and brain play a critical role in the pathogenesis of pd. |
2021-05-28 |
2023-08-13 |
mouse |
| Fernanda Leite, Laura Ribeir. Dopaminergic Pathways in Obesity-Associated Inflammation. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 15. issue 1. 2021-05-27. PMID:31317376. |
while the role of dopaminergic pathways in immune-mediated diseases has been intensively investigated in neurodegenerative diseases, dopaminergic immunomodulation in obesity-associated inflammation is largely unknown. |
2021-05-27 |
2023-08-13 |
human |