| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Sergeant, A Wattez, A Delacourt. Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: tau pathologies with exclusively "exon 10" isoforms. Journal of neurochemistry. vol 72. issue 3. 1999-03-18. PMID:10037497. |
together, tau isoforms with exon 10 clearly differentiate three groups of neurodegenerative diseases: ad, pid, and psp/cbd. |
1999-03-18 |
2023-08-12 |
Not clear |
| K K Burkhart, D C Beard, R A Lehman, M L Billingsle. Alterations in tau phosphorylation in rat and human neocortical brain slices following hypoxia and glucose deprivation. Experimental neurology. vol 154. issue 2. 1999-02-04. PMID:9878182. |
highly phosphorylated tau does not bind microtubules and is the main component of the paired helical filaments seen in alzheimer's and related neurodegenerative diseases. |
1999-02-04 |
2023-08-12 |
human |
| M Hong, V Zhukareva, V Vogelsberg-Ragaglia, Z Wszolek, L Reed, B I Miller, D H Geschwind, T D Bird, D McKeel, A Goate, J C Morris, K C Wilhelmsen, G D Schellenberg, J Q Trojanowski, V M Le. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science (New York, N.Y.). vol 282. issue 5395. 1998-12-28. PMID:9836646. |
tau proteins aggregate as cytoplasmic inclusions in a number of neurodegenerative diseases, including alzheimer's disease and hereditary frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17). |
1998-12-28 |
2023-08-12 |
Not clear |
| M G Spillantini, M Goeder. Tau protein pathology in neurodegenerative diseases. Trends in neurosciences. vol 21. issue 10. 1998-12-18. PMID:9786340. |
tau protein pathology in neurodegenerative diseases. |
1998-12-18 |
2023-08-12 |
Not clear |
| M Goedert, R Jakes, R A Crowther, M Hasegawa, M J Smith, M G Spillantin. Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases. Biochemical Society transactions. vol 26. issue 3. 1998-12-11. PMID:9765897. |
intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases. |
1998-12-11 |
2023-08-12 |
Not clear |
| K Okuizumi, H Takano, K Seki, Y Onishi, Y Horikawa, S Tsuj. Genetic polymorphism of the tau gene and neurodegenerative diseases with tau pathology among Japanese. Annals of neurology. vol 44. issue 4. 1998-11-06. PMID:9778275. |
genetic polymorphism of the tau gene and neurodegenerative diseases with tau pathology among japanese. |
1998-11-06 |
2023-08-12 |
Not clear |
| N Sasaki, R Fukatsu, K Tsuzuki, Y Hayashi, T Yoshida, N Fujii, T Koike, I Wakayama, R Yanagihara, R Garruto, N Amano, Z Makit. Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases. The American journal of pathology. vol 153. issue 4. 1998-10-28. PMID:9777946. |
in this study, we examined the immunohistochemical localization of ages, amyloid beta protein (a beta), apolipoprotein e (apoe), and tau protein in senile plaques, neurofibrillary tangles (nfts), and cerebral amyloid angiopathy (caa) in alzheimer's disease and other neurodegenerative diseases (progressive supranuclear palsy, pick's disease, and guamanian amyotrophic lateral sclerosis/parkinsonism-dementia complex). |
1998-10-28 |
2023-08-12 |
Not clear |
| J W Terryberry, G Thor, J B Pete. Autoantibodies in neurodegenerative diseases: antigen-specific frequencies and intrathecal analysis. Neurobiology of aging. vol 19. issue 3. 1998-09-16. PMID:9661995. |
the frequency of autoantibodies (aabs) was surveyed in several neurodegenerative diseases, other neurological diseases, and controls using antigen-specific eias for neurofilament heavy subunit, tubulin, glial fibrillary acidic protein, s100 protein, tau, beta-amyloid peptide, myelin basic protein, and heparan sulfate proteoglycan. |
1998-09-16 |
2023-08-12 |
Not clear |
| M G Spillantini, J R Murrell, M Goedert, M R Farlow, A Klug, B Ghett. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 13. 1998-08-06. PMID:9636220. |
familial multiple system tauopathy with presenile dementia (mstd) is a neurodegenerative disease with an abundant filamentous tau protein pathology. |
1998-08-06 |
2023-08-12 |
Not clear |
| K Ikeda, H Akiyama, T Arai, T Nishimur. Glial tau pathology in neurodegenerative diseases: their nature and comparison with neuronal tangles. Neurobiology of aging. vol 19. issue 1 Suppl. 1998-06-12. PMID:9562475. |
glial tau pathology in neurodegenerative diseases: their nature and comparison with neuronal tangles. |
1998-06-12 |
2023-08-12 |
Not clear |
| K Ikeda, H Akiyama, T Arai, T Nishimur. Glial tau pathology in neurodegenerative diseases: their nature and comparison with neuronal tangles. Neurobiology of aging. vol 19. issue 1 Suppl. 1998-06-12. PMID:9562475. |
tau pathology in neurodegenerative diseases takes heterogenous forms. |
1998-06-12 |
2023-08-12 |
Not clear |
| J Kuret, G S Johnson, D Cha, E R Christenson, A J DeMaggio, M F Hoekstr. Casein kinase 1 is tightly associated with paired-helical filaments isolated from Alzheimer's disease brain. Journal of neurochemistry. vol 69. issue 6. 1997-12-12. PMID:9375684. |
because of its tight association with phfs and its phosphate-directed substrate selectivity, casein kinase 1 is positioned to participate in the pathological hyperphosphorylation of tau protein that is observed in neurodegenerative diseases such as alzheimer's disease. |
1997-12-12 |
2023-08-12 |
Not clear |
| H Arai, Y Morikawa, M Higuchi, T Matsui, C M Clark, M Miura, N Machida, V M Lee, J Q Trojanowski, H Sasak. Cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology. Biochemical and biophysical research communications. vol 236. issue 2. 1997-08-28. PMID:9240421. |
cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology. |
1997-08-28 |
2023-08-12 |
Not clear |
| H Arai, Y Morikawa, M Higuchi, T Matsui, C M Clark, M Miura, N Machida, V M Lee, J Q Trojanowski, H Sasak. Cerebrospinal fluid tau levels in neurodegenerative diseases with distinct tau-related pathology. Biochemical and biophysical research communications. vol 236. issue 2. 1997-08-28. PMID:9240421. |
our study suggests that tau may accumulate in the csf of patients with certain neurodegenerative diseases other than ad and that measurement of csf-tau may not distinguish ad from dlb. |
1997-08-28 |
2023-08-12 |
Not clear |
| T Nishimura, K Ikeda, H Akiyama, T Arai, H Kondo, M Okochi, Y Furiya, H Mori, T Oda, M Kato, E Isek. Glial tau-positive structures lack the sequence encoded by exon 3 of the tau protein gene. Neuroscience letters. vol 224. issue 3. 1997-07-18. PMID:9131663. |
we have investigated immunohistochemically the expression of exon 3-derived fragment (e-3) of tau protein in brains of patients with alzheimer's disease (ad) and other neurodegenerative diseases in which the abnormal accumulation of tau protein takes place. |
1997-07-18 |
2023-08-12 |
Not clear |
| M G Spillantini, M Goedert, R A Crowther, J R Murrell, M R Farlow, B Ghett. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 8. 1997-05-22. PMID:9108114. |
neurofibrillary lesions made of hyperphosphorylated microtubule-associated protein tau constitute not only one of the defining neuropathological features of alzheimer disease but also are present in a number of other neurodegenerative diseases with dementia. |
1997-05-22 |
2023-08-12 |
Not clear |
| C Conrad, A Andreadis, J Q Trojanowski, D W Dickson, D Kang, X Chen, W Wiederholt, L Hansen, E Masliah, L J Thal, R Katzman, Y Xia, T Saito. Genetic evidence for the involvement of tau in progressive supranuclear palsy. Annals of neurology. vol 41. issue 2. 1997-03-12. PMID:9029080. |
a dinucleotide repeat polymorphism in a tau intron was identified and used in a case-control study to analyze the genetic association of tau with several neurodegenerative diseases with tau pathology. |
1997-03-12 |
2023-08-12 |
human |
| M B Feany, D W Dickso. Neurodegenerative disorders with extensive tau pathology: a comparative study and review. Annals of neurology. vol 40. issue 2. 1996-10-16. PMID:8773594. |
recent biochemical and molecular biological studies have identified the microtubule-binding protein tau as the predominant component of these and related inclusions, and have provided powerful new reagents for the study of neurodegenerative diseases. |
1996-10-16 |
2023-08-12 |
Not clear |
| C Gervasi, B G Szar. The Xenopus laevis homologue to the neuronal cyclin-dependent kinase (cdk5) is expressed in embryos by gastrulation. Brain research. Molecular brain research. vol 33. issue 2. 1996-10-09. PMID:8750877. |
phosphorylation of the neuronal cytoskeletal proteins nf-h, nf-m and tau is important for normal axonal development, and is involved in axonal injury and neurodegenerative diseases. |
1996-10-09 |
2023-08-12 |
rat |
| M B Feany, D W Dickso. Widespread cytoskeletal pathology characterizes corticobasal degeneration. The American journal of pathology. vol 146. issue 6. 1995-07-13. PMID:7778678. |
the further definition of cbd pathology refines the diagnosis and pathophysiological understanding of this unique disease and has important implications for other neurodegenerative diseases, like alzheimer's disease, characterized by abnormal tau deposition. |
1995-07-13 |
2023-08-12 |
Not clear |