| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huihui Li, Yan Guo, Junlin Teng, Mingxiao Ding, Albert Cheung Hoi Yu, Jianguo Che. 14-3-3gamma affects dynamics and integrity of glial filaments by binding to phosphorylated GFAP. Journal of cell science. vol 119. issue Pt 21. 2007-01-16. PMID:17032734. |
recent findings indicated a protective role of gfap in ischemic brain, injured spinal cord, and in neurodegenerative disease. |
2007-01-16 |
2023-08-12 |
Not clear |
| Huihui Li, Yan Guo, Junlin Teng, Mingxiao Ding, Albert Cheung Hoi Yu, Jianguo Che. 14-3-3gamma affects dynamics and integrity of glial filaments by binding to phosphorylated GFAP. Journal of cell science. vol 119. issue Pt 21. 2007-01-16. PMID:17032734. |
this data demonstrates that 14-3-3gamma contributes to the regulation of dynamics of gfap filaments, which may contribute to the stability of the cytoskeleton and the mechanisms of central nervous system neurodegenerative disease. |
2007-01-16 |
2023-08-12 |
Not clear |
| Irina Rozovsky, Min Wei, Todd E Morgan, Caleb E Finc. Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708446. |
in contrast during normal aging without neurodegenerative diseases, astrocytes display increasing activation, with progressive increases of glial fibrillary acidic protein (gfap) beginning before midlife. |
2005-05-09 |
2023-08-12 |
Not clear |
| Raymonde Porchet, Alphonse Probst, Constantin Bouras, Eduarda Dráberová, Pavel Dráber, Beat M Riedere. Analysis of glial acidic fibrillary protein in the human entorhinal cortex during aging and in Alzheimer's disease. Proteomics. vol 3. issue 8. 2004-05-17. PMID:12923773. |
gfap may be used as an additional but not exclusive diagnostic tool in the evaluation of neurodegenerative diseases because its levels change with age and respond to senile plaque and tangle formation. |
2004-05-17 |
2023-08-12 |
human |
| Anders Lade Nielsen, Ida E Holm, Marianne Johansen, Bjarne Bonven, Poul Jørgensen, Arne Lund Jørgense. A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins. The Journal of biological chemistry. vol 277. issue 33. 2002-09-20. PMID:12058025. |
accordingly, gfap epsilon should be taken into consideration when studying neurodegenerative diseases. |
2002-09-20 |
2023-08-12 |
human |
| I Hozumi, T Inuzuka, S Tsuj. Brain injury and growth inhibitory factor (GIF)--a minireview. Neurochemical research. vol 23. issue 3. 1998-03-26. PMID:9482244. |
in neurodegenerative diseases in humans, gif expression levels are reduced whereas gfap expression levels are markedly induced in reactive astrocytes. |
1998-03-26 |
2023-08-12 |
rat |
| K Renkawek, C E Voorter, G J Bosman, F P van Workum, W W de Jon. Expression of alpha B-crystallin in Alzheimer's disease. Acta neuropathologica. vol 87. issue 2. 1994-06-01. PMID:8171966. |
under pathological conditions, the expression of alpha b-crystallin increases in proliferating astrocytes, which suggests that this protein, in addition to glial fibrillary acidic protein (gfap), can be a marker for gliosis in neurodegenerative diseases. |
1994-06-01 |
2023-08-12 |
Not clear |