| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Sun, Carlos Blanco-Centurion, Bingyu Zou, Emmaline Bendell, Priyattam J Shiromani, Meng Li. Amygdala GABA Neurons Project To vlPAG And mPFC. IBRO reports. vol 6. 2020-09-30. PMID:31193158. |
based on these projections we suggest that amygdala gaba neurons may be involved in triggering emotionally-induced cataplexy in the sleep disorder, narcolepsy. |
2020-09-30 |
2023-08-13 |
mouse |
| Eric Murillo-Rodríguez, Diana Millán-Aldaco, Marcela Palomero-Rivero, Daniela Morales-Lara, Raphael Mechoulam, René Drucker-Colí. Cannabidiol Partially Blocks the Excessive Sleepiness in Hypocretindeficient Rats: Preliminary Data. CNS & neurological disorders drug targets. vol 18. issue 9. 2020-09-24. PMID:31642794. |
excessive daytime sleepiness and cataplexy are among the symptoms of narcolepsy, a sleep disorder caused by the loss of hypocretin/orexin (hcrt/ox) neurons placed into the hypothalamus (lh). |
2020-09-24 |
2023-08-13 |
rat |
| Fernando Cascio Barros Lima, Elias Borges do Nascimento Junior, Silmar Silva Teixeira, Fernando Morgadinho Coelho, Giuliano da Paz Oliveir. Thinking outside the box: cataplexy without narcolepsy. Sleep medicine. vol 61. 2020-07-28. PMID:31427075. |
thinking outside the box: cataplexy without narcolepsy. |
2020-07-28 |
2023-08-13 |
Not clear |
| Kristian Bolin, Per-Åke Niska, Laura Pirhonen, Pontus Wasling, Anne-Marie Landtblo. The cost utility of pitolisant as narcolepsy treatment. Acta neurologica Scandinavica. vol 141. issue 4. 2020-07-20. PMID:31838740. |
pitolisant is the first inverse agonist of the histamine h3 receptor to be prescribed for the treatment of narcolepsy with and without cataplexy. |
2020-07-20 |
2023-08-13 |
Not clear |
| Mihoko Shimada, Taku Miyagawa, Akari Takeshima, Akiyoshi Kakita, Hiromi Toyoda, Kazuhiro Niizato, Kenichi Oshima, Katsushi Tokunaga, Makoto Hond. Epigenome-wide association study of narcolepsy-affected lateral hypothalamic brains, and overlapping DNA methylation profiles between narcolepsy and multiple sclerosis. Sleep. vol 43. issue 1. 2020-07-13. PMID:31556946. |
narcolepsy with cataplexy is a sleep disorder caused by a deficiency in hypocretin neurons in the lateral hypothalamus (lh). |
2020-07-13 |
2023-08-13 |
Not clear |
| Natasha Morales Drissi, Marcel Warntjes, Alexander Wessén, Attila Szakacs, Niklas Darin, Tove Hallböök, Anne-Marie Landtblom, Helena Gauffin, Maria Engströ. Structural anomaly in the reticular formation in narcolepsy type 1, suggesting lower levels of neuromelanin. NeuroImage. Clinical. vol 23. 2020-06-29. PMID:31174102. |
the aim of this study was to investigate structural changes in the brain stem of adolescents with narcolepsy, a disorder characterized by excessive daytime sleepiness, fragmented night-time sleep, and cataplexy. |
2020-06-29 |
2023-08-13 |
Not clear |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
anterior hippocampus volume loss in narcolepsy with cataplexy. |
2020-05-20 |
2023-08-13 |
human |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
narcolepsy with cataplexy is a lifelong disease resulting from the loss of hypocretin neurons in the hypothalamus; structural changes are not, however, limited only to the hypothalamus. |
2020-05-20 |
2023-08-13 |
human |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
we previously revealed an overall hippocampal volume loss in narcolepsy with cataplexy. |
2020-05-20 |
2023-08-13 |
human |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
the aim of this study is to describe the volume reduction of the anterior and posterior parts of the hippocampus in patients with narcolepsy with cataplexy in comparison with a control group. |
2020-05-20 |
2023-08-13 |
human |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
manual magnetic resonance imaging hippocampal volumetry was performed in 48 patients with narcolepsy with cataplexy and in 37 controls using the manual delineation technique in the scanview program. |
2020-05-20 |
2023-08-13 |
human |
| b' Martina K\\xc5\\x99e\\xc4\\x8dkov\\xc3\\xa1, David Kemlink, Karel \\xc5\\xa0onka, Jan Kr\\xc3\\xa1sensk\\xc3\\xbd, Jitka Bu\\xc5\\xa1kov\\xc3\\xa1, Manuela Van\\xc4\\x9b\\xc4\\x8dkov\\xc3\\xa1, Veronika N\\xc4\\x9bmcov\\xc3\\xa. Anterior hippocampus volume loss in narcolepsy with cataplexy. Journal of sleep research. vol 28. issue 4. 2020-05-20. PMID:30421546.' |
there was a significant absolute loss of the total volume of the anterior hippocampus (sum of left and right) in patients with narcolepsy with cataplexy as compared with the controls (10.5%, p = .03 ancova after correcting for total brain volume and multiple testing). |
2020-05-20 |
2023-08-13 |
human |
| Célia Lacaux, Charlotte Izabelle, Giulio Santantonio, Laure De Villèle, Johanna Frain, Todd Lubart, Fabio Pizza, Giuseppe Plazzi, Isabelle Arnulf, Delphine Oudiett. Increased creative thinking in narcolepsy. Brain : a journal of neurology. vol 142. issue 7. 2020-05-18. PMID:31143939. |
narcolepsy is characterized by falling asleep directly into rapid eye movement sleep, states of dissociated wakefulness and rapid eye movement sleep (cataplexy, hypnagogic hallucinations, sleep paralysis, rapid eye movement sleep behaviour disorder and lucid dreaming) and a high dream recall frequency. |
2020-05-18 |
2023-08-13 |
human |
| Célia Lacaux, Charlotte Izabelle, Giulio Santantonio, Laure De Villèle, Johanna Frain, Todd Lubart, Fabio Pizza, Giuseppe Plazzi, Isabelle Arnulf, Delphine Oudiett. Increased creative thinking in narcolepsy. Brain : a journal of neurology. vol 142. issue 7. 2020-05-18. PMID:31143939. |
most symptoms of narcolepsy (including sleepiness, hypnagogic hallucinations, sleep paralysis, lucid dreaming, and rapid eye movement sleep behaviour disorder, but not cataplexy) were associated with higher scores on the test of creative profile. |
2020-05-18 |
2023-08-13 |
human |
| Florence B Pomares, Soufiane Boucetta, Francis Lachapelle, Jason Steffener, Jacques Montplaisir, Jungho Cha, Hosung Kim, Thien Thanh Dang-V. Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia. Sleep. vol 42. issue 11. 2020-05-13. PMID:31328786. |
idiopathic hypersomnia (ih) is characterized by excessive daytime sleepiness but, in contrast to narcolepsy, does not involve cataplexy, sleep-onset rem periods, or any consistent hypocretin-1 deficiency. |
2020-05-13 |
2023-08-13 |
human |
| Hilde T Juvodden, Dag Alnæs, Martina J Lund, Espen Dietrichs, Per M Thorsby, Lars T Westlye, Stine Knudse. Hypocretin-deficient narcolepsy patients have abnormal brain activation during humor processing. Sleep. vol 42. issue 7. 2020-03-23. PMID:30923809. |
to assess brain activation patterns in response to fun-rated and neutral-rated movies we performed functional magnetic resonance imaging (fmri) during a humor-paradigm in narcolepsy type 1 (nt1) patients with cataplexy (muscle atonia triggered by emotions) and controls. |
2020-03-23 |
2023-08-13 |
Not clear |
| Ali Seifinejad, Sha Li, Cyril Mikhail, Anne Vassalli, Sylvain Pradervand, Yoan Arribat, Hassan Pezeshgi Modarres, Bridget Allen, Rosalind M John, Francesca Amati, Mehdi Taft. Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 34. 2020-03-23. PMID:31375626. |
loss of hcrt (ligands or receptors) causes the sleep disorder narcolepsy with cataplexy in humans and in animal models. |
2020-03-23 |
2023-08-13 |
mouse |
| Stefano Vandi, Fabio Pizza, Elena Antelmi, Giulia Neccia, Martina Iloti, Alice Mazzoni, Patrizia Avoni, Giuseppe Plazz. A standardized test to document cataplexy. Sleep medicine. vol 53. 2020-03-09. PMID:29276000. |
cataplexy is the pathognomonic symptom of narcolepsy type 1 (nt1). |
2020-03-09 |
2023-08-13 |
Not clear |
| Bei Huang, Zhenying Qian, Zongwen Wang, Jihui Zhang, Kun Chen, Tao Xu, Jijun Wang, David F Cechetto, Zhongxin Zhao, Huijuan W. Fluctuation of primary motor cortex excitability during cataplexy in narcolepsy. Annals of clinical and translational neurology. vol 6. issue 2. 2020-02-18. PMID:30847354. |
fluctuation of primary motor cortex excitability during cataplexy in narcolepsy. |
2020-02-18 |
2023-08-13 |
Not clear |
| Bei Huang, Zhenying Qian, Zongwen Wang, Jihui Zhang, Kun Chen, Tao Xu, Jijun Wang, David F Cechetto, Zhongxin Zhao, Huijuan W. Fluctuation of primary motor cortex excitability during cataplexy in narcolepsy. Annals of clinical and translational neurology. vol 6. issue 2. 2020-02-18. PMID:30847354. |
cataplexy is a complicated and dynamic process in narcolepsy type 1 (nt1) patients. |
2020-02-18 |
2023-08-13 |
Not clear |