| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Giorgia Varallo, Christian Franceschini, Giada Rapelli, Corrado Zenesini, Valentina Baldini, Flavia Baccari, Elena Antelmi, Fabio Pizza, Luca Vignatelli, Francesco Biscarini, Francesca Ingravallo, Giuseppe Plazz. Navigating narcolepsy: exploring coping strategies and their association with quality of life in patients with narcolepsy type 1. Scientific reports. vol 14. issue 1. 2024-05-24. PMID:38783152. |
narcolepsy type 1 (nt1) is a chronic neurological disorder characterized by symptoms such as excessive daytime sleepiness, sudden sleep episodes, disrupted nocturnal sleep, cataplexy, sleep paralysis, and hypnagogic hallucinations, which significantly impact the overall well-being and quality of life of individuals. |
2024-05-24 |
2024-05-27 |
human |
| Erafat D Rehim, Martina Vendram. Cataplexy Mistaken for Seizures in a Patient With Undiagnosed Narcolepsy Type I. Cureus. vol 16. issue 4. 2024-05-06. PMID:38707044. |
cataplexy mistaken for seizures in a patient with undiagnosed narcolepsy type i. narcolepsy type 1 is a sleep disorder, with cataplexy as its cardinal feature, characterized by sudden decrease or loss of muscle tone triggered by strong emotions. |
2024-05-06 |
2024-05-08 |
Not clear |
| Vinay Mandagere, Dane Raymen. Atypical isolated cataplexy: two case reports and a mini-review. Neurocase. 2024-04-27. PMID:38678310. |
cataplexy is one of the essential diagnostic features of narcolepsy type 1 (nt1). |
2024-04-27 |
2024-04-30 |
Not clear |
| Xianhui Zhong, Yuqing Yuan, Qingqing Zhan, Tiantian Yin, Chengxin Ku, Yuxin Liu, Fen Wang, Yongmin Ding, Liying Deng, Wei Wu, Liang Xi. Cell-based versus enzyme-linked immunosorbent assay for detection of anti-Tribbles homolog 2 autoantibodies in Chinese patients with narcolepsy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2024-02-06. PMID:38318919. |
the levels of anti-tribbles homolog 2 (trib2) autoantibodies are elevated in the sera of some patients with narcolepsy with cataplexy. |
2024-02-06 |
2024-02-09 |
mouse |
| Wejdan Hakami, Farah Thabet, Amal Alhashem, Abdulaziz Alghamdi, Saad Alshahwan, Fowzan S Alkuraya, Brahim Tabark. Bi-allelic variants in HCRT cause autosomal recessive narcolepsy. Neurogenetics. 2024-01-19. PMID:38240911. |
pathogenic variants in hcrt cause autosomal recessive narcolepsy with cataplexy. |
2024-01-19 |
2024-01-21 |
Not clear |
| Wejdan Hakami, Farah Thabet, Amal Alhashem, Abdulaziz Alghamdi, Saad Alshahwan, Fowzan S Alkuraya, Brahim Tabark. Bi-allelic variants in HCRT cause autosomal recessive narcolepsy. Neurogenetics. 2024-01-19. PMID:38240911. |
genetic testing of the hcrt gene should be conducted in specific subgroups of narcolepsy, particularly those with early onset, familial cases, and a predominantly cataplexy phenotype. |
2024-01-19 |
2024-01-21 |
Not clear |
| Dandan Sheng, Peihong Li, Zheng Xiao, Xinru Li, Jing Liu, Bo Xiao, Weiping Liu, Luo Zho. Identification of bidirectional causal links between gut microbiota and narcolepsy type 1 using Mendelian randomization. Sleep. 2024-01-04. PMID:38174762. |
narcolepsy type 1 (nt1), characterized by cataplexy and orexin deficiency, is a rare and frequently debilitating neurological disorder. |
2024-01-04 |
2024-01-06 |
Not clear |
| Parya Valizadeh, Sara Momtazmanesh, Giuseppe Plazzi, Nima Rezae. Connecting the dots: An updated review of the role of autoimmunity in narcolepsy and emerging immunotherapeutic approaches. Sleep medicine. vol 113. 2023-12-21. PMID:38128432. |
narcolepsy type 1 (nt1) is a chronic disorder characterized by pathological daytime sleepiness and cataplexy due to the disappearance of orexin immunoreactive neurons in the hypothalamus. |
2023-12-21 |
2023-12-24 |
Not clear |
| Elena S Wenz, Mink S Schinkelshoek, Ulf Kallweit, Rolf Fronczek, Rana Rezaei, Ramin Khatami, Gert Jan Lammers, Claudio L A Bassett. Narcolepsy type 1 and Sydenham chorea - Report of 3 cases and review of the literature. Sleep medicine. vol 112. 2023-11-05. PMID:37925849. |
narcolepsy type 1 (nt1) is an immune-mediated disorder characterized by excessive daytime sleepiness, cataplexy, low levels of hypocretin-1 in the cerebrospinal fluid, and a strong association with the hla dqb1*06:02 allele. |
2023-11-05 |
2023-11-08 |
Not clear |
| Marco Menchetti, Francesco Biscarini, Giombattista Sallemi, Elena Antelmi, Christian Franceschini, Stefano Vandi, Giulia Neccia, Valentina Baldini, Giuseppe Plazzi, Fabio Pizz. Phenomenology and psychiatric correlates of pseudocataplexy. Sleep. 2023-09-08. PMID:37682005. |
pseudocataplexy is a rare functional neurological disorder that mimics cataplexy, pathognomonic for narcolepsy type 1 (nt1). |
2023-09-08 |
2023-10-07 |
Not clear |
| L Barateau, F Pizza, S Chenini, L Peter-Derex, Y Dauvillier. Narcolepsies, update in 2023. Revue neurologique. 2023-08-27. PMID:37634997. |
narcolepsy type 1 (nt1) and type 2 (nt2), also known as narcolepsy with and without cataplexy, are sleep disorders that benefited from major scientific advances over the last two decades. |
2023-08-27 |
2023-09-07 |
Not clear |
| Yoshimasa Koyam. The role of orexinergic system in the regulation of cataplexy. Peptides. 2023-08-20. PMID:37598758. |
cataplexy is the most striking symptom of narcolepsy, characterized by abrupt muscle paralysis induced by emotional stimuli, and has been considered pathological activation of rem sleep atonia system. |
2023-08-20 |
2023-09-07 |
Not clear |
| Brandon A Toth, Katie S Chang, Christian R Burges. Striatal dopamine regulates sleep states and narcolepsy-cataplexy. bioRxiv : the preprint server for biology. 2023-07-03. PMID:37397994. |
patients with the sleep disorder narcolepsy suffer from excessive daytime sleepiness, disrupted nighttime sleep, and cataplexy - the abrupt loss of postural muscle tone (atonia) during wakefulness, often triggered by strong emotion. |
2023-07-03 |
2023-08-14 |
Not clear |
| Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. |
2023-06-02 |
2023-08-14 |
human |
| Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
patients with type 1 narcolepsy often also present with cataplexy, the sudden paralysis of voluntary muscles which is triggered by strong emotions (e.g., laughter in humans, social play in dogs, and chocolate in rodents). |
2023-06-02 |
2023-08-14 |
human |
| Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
the amygdala is a crucial emotion-processing center of the brain; however, little is known about the role of the amygdala in sleep/wake and narcolepsy with cataplexy. |
2023-06-02 |
2023-08-14 |
human |
| Haniyyah Sardar, Andrea N Goldstein-Piekarski, William J Giardin. Amygdala neurocircuitry at the interface between emotional regulation and narcolepsy with cataplexy. Frontiers in neuroscience. vol 17. 2023-06-02. PMID:37266541. |
we propose that detailed examinations of amygdala neurocircuitry controlling transitions between emotional arousal states may substantially advance progress in understanding the etiology of narcolepsy with cataplexy, leading to enhanced treatment opportunities. |
2023-06-02 |
2023-08-14 |
human |
| Louise Piilgaard, Laura Rose, Jessica L Justinussen, Camille Gylling Hviid, René Lemcke, Petrine Wellendorph, Birgitte Rahbek Kornu. Non-invasive detection of narcolepsy type I phenotypical features and disease progression by continuous home-cage monitoring of activity in two mouse models: the HCRT-KO and DTA model. Sleep. 2023-05-20. PMID:37210587. |
narcolepsy type 1 (nt1) is a neurological disorder caused by disruption of hypocretin (hcrt; or orexin) neurotransmission leading to fragmented sleep/wake states, excessive daytime sleepiness (eds), and cataplexy (abrupt muscle atonia during wakefulness). |
2023-05-20 |
2023-08-14 |
mouse |
| Ikram Ayoub, Yves Dauvilliers, Lucie Barateau, Thaïs Vermeulen, Emmanuelle Mouton-Barbosa, Marlène Marcellin, Anne Gonzalez-de-Peredo, Catharina C Gross, Abdelhadi Saoudi, Roland Libla. Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system. Frontiers in immunology. vol 14. 2023-05-01. PMID:37122721. |
narcolepsy type 1 (nt1) is a rare, chronic and disabling neurological disease causing excessive daytime sleepiness and cataplexy. |
2023-05-01 |
2023-08-14 |
Not clear |
| Ali Seifinejad, Mergim Ramosaj, Ling Shan, Sha Li, Marie-Laure Possovre, Corinne Pfister, Rolf Fronczek, Lee A Garrett-Sinha, David Frieser, Makoto Honda, Yoan Arribat, Dogan Grepper, Francesca Amati, Marie Picot, Andrea Agnoletto, Christian Iseli, Nicolas Chartrel, Roland Liblau, Gert J Lammers, Anne Vassalli, Mehdi Taft. Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 19. 2023-05-01. PMID:37126681. |
narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic neuropeptide hypocretin/orexin (hcrt), unanimously believed to result from autoimmune destruction of hypocretin-producing neurons. |
2023-05-01 |
2023-08-14 |
mouse |