| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Wang, Xuelian He, Huyan Meng, Yi Li, Phillip Dmitriev, Feng Tian, Jessica C Page, Q Richard Lu, Zhigang H. Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and Microglia. Neuron. vol 108. issue 5. 2021-01-27. PMID:33108748. |
in this study, we found that, in injured optic nerves, oligodendrocyte precursor cells (opcs) undergo transient proliferation but fail to differentiate into mature myelination-competent oligodendrocytes, reminiscent of what is observed in human progressive multiple sclerosis. |
2021-01-27 |
2023-08-13 |
human |
| Lu Wang, Hanyu Yang, Caixia Zang, Yi Dong, Junmei Shang, Jiajing Chen, Yue Wang, Hui Liu, Zihong Zhang, Heng Xu, Xiuqi Bao, Dan Zhan. CXCR2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis. Neurobiology of disease. vol 134. 2021-01-13. PMID:31678404. |
cxcr2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis. |
2021-01-13 |
2023-08-13 |
mouse |
| Nassim Abi Chahine, Paul L. Stem Cells Therapy for Multiple Sclerosis. Advances in experimental medicine and biology. vol 1266. 2021-01-08. PMID:33105497. |
multiple sclerosis (ms) is the most frequent demyelinating disease of the central nervous system (cns) associated with inflammatory plaques of white matter demyelination, oligodendrocyte destruction, reactive gliosis and axonal degeneration. |
2021-01-08 |
2023-08-13 |
Not clear |
| Monica R Langley, Erin M Triplet, Isobel A Scarisbric. Dietary influence on central nervous system myelin production, injury, and regeneration. Biochimica et biophysica acta. Molecular basis of disease. vol 1866. issue 7. 2021-01-05. PMID:32224154. |
oligodendrocyte loss and myelin destruction, as occurs in multiple sclerosis (ms), leaves axons vulnerable to degeneration and permanent neurological deficits ensue. |
2021-01-05 |
2023-08-13 |
Not clear |
| Alireza Lotfi, Mitra Soleimani, Nazem Ghasem. Astaxanthin Reduces Demyelination and Oligodendrocytes Death in A Rat Model of Multiple Sclerosis. Cell journal. vol 22. issue 4. 2021-01-01. PMID:32347051. |
in this study, we aimed to evaluate the protective potential of ast in inhibiting demyelination and oligodendrocyte death in a rat model of multiple sclerosis (ms). |
2021-01-01 |
2023-08-13 |
rat |
| Mohamed B Hassan, Caroline Stern, Eoin P Flanagan, Sean J Pittock, Amy Kunchok, Robert C Foster, Jiraporn Jitprapaikulsan, David O Hodge, M Tariq Bhatti, John J Che. Population-Based Incidence of Optic Neuritis in the Era of Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Antibodies. American journal of ophthalmology. vol 220. 2020-12-22. PMID:32707199. |
to re-evaluate the population-based incidence of optic neuritis in the era of aquaporin-4-immunoglobulin g (aqp4-igg) and myelin oligodendrocyte glycoprotein (mog)-igg, which are biomarkers of optic neuritis that is distinct from multiple sclerosis (ms). |
2020-12-22 |
2023-08-13 |
Not clear |
| Yoshiki Takai, Tatsuro Misu, Kimihiko Kaneko, Norio Chihara, Koichi Narikawa, Satoko Tsuchida, Hiroya Nishida, Takashi Komori, Morinobu Seki, Teppei Komatsu, Kiyotaka Nakamagoe, Toshimasa Ikeda, Mari Yoshida, Toshiyuki Takahashi, Hirohiko Ono, Shuhei Nishiyama, Hiroshi Kuroda, Ichiro Nakashima, Hiroyoshi Suzuki, Monika Bradl, Hans Lassmann, Kazuo Fujihara, Masashi Aok. Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study. Brain : a journal of neurology. vol 143. issue 5. 2020-12-14. PMID:32412053. |
conformation-sensitive antibodies against myelin oligodendrocyte glycoprotein (mog) are detectable in patients with optic neuritis, myelitis, opticomyelitis, acute or multiphasic disseminated encephalomyelitis (adem/mdem) and brainstem/cerebral cortical encephalitis, but are rarely detected in patients with prototypic multiple sclerosis. |
2020-12-14 |
2023-08-13 |
Not clear |
| Young Nam Kwon, Boram Kim, Sohyun Ahn, Jaeyoung Seo, Sang Beom Kim, Sung Sang Yoon, Jung-Joon Sung, Youn Soo Choi, Sung-Min Ki. Serum level of IL-1β in patients with inflammatory demyelinating disease: Marked upregulation in the early acute phase of MOG antibody associated disease (MOGAD). Journal of neuroimmunology. vol 348. 2020-12-14. PMID:32919144. |
to evaluate the serum cytokine profiles in patients with myelin oligodendrocyte glycoproteins antibody associated disease (mogad), compared to those in neuromyelitis optica spectrum disorder with aquaporin-4 immunoglobulin g (apq4-igg+ nmosd), multiple sclerosis (ms), and other inflammatory demyelinating diseases (idds). |
2020-12-14 |
2023-08-13 |
Not clear |
| Malou Janssen, Arlette L Bruijstens, Jamie van Langelaar, YuYi Wong, Annet F Wierenga-Wolf, Marie-José Melief, Liza Rijvers, E Daniëlle van Pelt, Joost Smolders, Beatrijs H Wokke, Marvin M van Luij. Naive B cells in neuromyelitis optica spectrum disorders: impact of steroid use and relapses. Brain communications. vol 2. issue 2. 2020-12-12. PMID:33305266. |
under complete treatment-naive circumstances, we found that naive mature/transitional b-cell ratios were reduced in the blood of 10 patients with aquaporin-4 immunoglobulin g-positive disease (neuromyelitis optica spectrum disorders) as compared to 11 both age- and gender-matched healthy controls, eight patients with myelin oligodendrocyte glycoprotein-immunoglobulin g-associated disorders and 10 patients with multiple sclerosis. |
2020-12-12 |
2023-08-13 |
Not clear |
| Maria Serena Paladini, Davide Marangon, Andrea C Rossetti, Alice Guidi, Giusy T Coppolino, Camilla Negri, Vittoria Spero, Maria Pia Abbracchio, Davide Lecca, Raffaella Molten. Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. Cellular and molecular neurobiology. 2020-12-01. PMID:33259004. |
prenatal stress impairs spinal cord oligodendrocyte maturation via bdnf signaling in the experimental autoimmune encephalomyelitis model of multiple sclerosis. |
2020-12-01 |
2023-08-13 |
mouse |
| Shuangshuang Zheng, Jingwei Zha. [Mechanisms underlying remyelination with special focus on demyelination models of multiple sclerosis]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences. vol 49. issue 4. 2020-10-20. PMID:32985167. |
failure to remyelinate and rewrap the demyelinated axons has been revealed as the major hurdle for treatment of multiple sclerosis (ms), and the bottleneck is the inability of oligodendrocyte progenitor cell (opc) to differentiate into mature oligodendrocyte. |
2020-10-20 |
2023-08-13 |
Not clear |
| Harald Hegen, Markus Reind. Recent developments in MOG-IgG associated neurological disorders. Therapeutic advances in neurological disorders. vol 13. 2020-10-09. PMID:33029200. |
in the past few years, acquired demyelinating syndromes of the central nervous system associated with antibodies against myelin oligodendrocyte glycoprotein (mog) have evolved into a new inflammatory disease entity distinct from neuromyelitis optica spectrum disorders or multiple sclerosis. |
2020-10-09 |
2023-08-13 |
Not clear |
| Bert A 't Hart, Robert Weisser. Myelin oligodendrocyte glycoprotein has a dual role in T cell autoimmunity against central nervous system myelin. Multiple sclerosis journal - experimental, translational and clinical. vol 2. 2020-10-01. PMID:28607715. |
myelin oligodendrocyte glycoprotein (mog) is a candidate primary target of the autoimmune attack on the central nervous system (cns) in multiple sclerosis (ms). |
2020-10-01 |
2023-08-13 |
Not clear |
| Deepali Mathur, Angela L Riffo-Campos, Josefa Castillo, Jeffery D Haines, Oscar G Vidaurre, Fan Zhang, Francisco Coret-Ferrer, Patrizia Casaccia, Bonaventura Casanova, Gerardo Lopez-Roda. Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28775680. |
bioenergetic failure in rat oligodendrocyte progenitor cells treated with cerebrospinal fluid derived from multiple sclerosis patients. |
2020-10-01 |
2023-08-13 |
rat |
| Laura Thomas, Laura Andrea Pasquin. Galectin-3-Mediated Glial Crosstalk Drives Oligodendrocyte Differentiation and (Re)myelination. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30258354. |
the present review summarizes gal-3 functions in the extracellular and intracellular space, its regulation and its internalization and secretion, with a focus on the current knowledge of gal-3 role in central nervous system (cns) health and disease, particularly oligodendrocyte (olg) differentiation, myelination and remyelination in experimental models of multiple sclerosis (ms). |
2020-10-01 |
2023-08-13 |
Not clear |
| Maria P Gontika, Maria C Anagnostoul. Anti-Myelin Oligodendrocyte Glycoprotein and Human Leukocyte Antigens as Markers in Pediatric and Adolescent Multiple Sclerosis: on Diagnosis, Clinical Phenotypes, and Therapeutic Responses. Multiple sclerosis international. vol 2018. 2020-10-01. PMID:30595920. |
anti-myelin oligodendrocyte glycoprotein and human leukocyte antigens as markers in pediatric and adolescent multiple sclerosis: on diagnosis, clinical phenotypes, and therapeutic responses. |
2020-10-01 |
2023-08-13 |
human |
| Sinead Healy, Jill McMahon, Una FitzGeral. UPR Induction Prevents Iron Accumulation and Oligodendrocyte Loss in Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30618588. |
upr induction prevents iron accumulation and oligodendrocyte loss in the accumulation of iron within the brain occurs in many chronic disorders including alzheimer's and parkinson's disease and multiple sclerosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Robert P Lisak, Joyce A Benjamin. Melanocortins, Melanocortin Receptors and Multiple Sclerosis. Brain sciences. vol 7. issue 8. 2020-09-30. PMID:28805746. |
we have focused on the expression and function of melanocortin receptors in oligodendroglia (ol), the myelin producing cells of the cns, with the goal of identifying new therapeutic approaches to decrease cns damage in multiple sclerosis as well as to promote repair. |
2020-09-30 |
2023-08-13 |
Not clear |
| Adriana Octaviana Dulame. The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies. Neural regeneration research. vol 12. issue 12. 2020-09-30. PMID:29323026. |
the contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies. |
2020-09-30 |
2023-08-13 |
Not clear |
| Adriana Octaviana Dulame. The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination therapeutic strategies. Neural regeneration research. vol 12. issue 12. 2020-09-30. PMID:29323026. |
in multiple sclerosis (ms), there is an imbalance between demyelination and remyelination processes, the last one performed by oligodendrocyte progenitor cells (opcs) and ols, resulting into a permanent demyelination, axonal damage and neuronal loss. |
2020-09-30 |
2023-08-13 |
Not clear |