| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aifen Liu, Jingyan Hu, Tzu-Shao Yeh, Chengniu Wang, Jilong Tang, Xiaohong Huang, Bin Chen, Liexiang Huangfu, Weili Yu, Lei Zhan. Neuroprotective Strategies for Stroke by Natural Products: Advances and Perspectives. Current neuropharmacology. 2023-07-17. PMID:37458258. |
then we propose the comprehensive neuroprotective mechanism of nps in cerebral ischemic stroke, which involves complex cascade processes of oxidative stress, mitochondrial damage, apoptosis or ferroptosis-related cell death, inflammatory response, and disruption of the blood- brain barrier (bbb). |
2023-07-17 |
2023-08-14 |
Not clear |
| Xia Liu, Qinlian Ye, Zhengzheng Huang, Xiuping Li, Liping Zhang, Xuan Liu, Yun-Cheng Wu, Ulf Brockmeier, Dirk M Hermann, Ya-Chao Wang, Lijie Re. BAG3 Overexpression Attenuates Ischemic Stroke Injury by Activating Autophagy and Inhibiting Apoptosis. Stroke. 2023-06-28. PMID:37377010. |
bag3 overexpression attenuates ischemic stroke injury by activating autophagy and inhibiting apoptosis. |
2023-06-28 |
2023-08-14 |
mouse |
| Gui-Ling Wang, Shu-Ying Xu, He-Qun Lv, Chao Zhang, Yong-Jun Pen. Electroacupuncture Inhibits Ferroptosis Induced by Cerebral Ischemia-reperfusion. Current neurovascular research. 2023-06-26. PMID:37357521. |
studies have shown that ea can relieve brain damage after ischemic stroke by inhibiting programmed cell death (pcd), such as apoptosis, necroptosis, and autophagy. |
2023-06-26 |
2023-08-14 |
Not clear |
| Yuxin Zhang, Huijuan Lou, Jing Lu, Xiaolei Tang, Tingting Pang, Siyuan Lei, Deyu Cong, Yufeng Wang, Liwei Su. Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy. Scientific reports. vol 13. issue 1. 2023-06-21. PMID:37344501. |
in conclusion, the present study showed that scalp acupuncture of vertex middle line and anterior oblique line of vertex temple may alleviate cerebral ischemic stroke by inhibiting er stress-accelerated apoptosis. |
2023-06-21 |
2023-08-14 |
rat |
| Pin Zhao, Jiapo Zhang, JianKe Kuai, Liya Li, Xuying Li, Namin Feng, Hailiang Du, Chen Li, Qiang Wang, Bin Den. TAT-PEP Alleviated Cognitive Impairment by Alleviating Neuronal Mitochondria Damage and Apoptosis After Cerebral Ischemic Reperfusion Injury. Molecular neurobiology. 2023-06-19. PMID:37335462. |
this study also suggests that tat-pep may be a potent neuroprotectant with therapeutic potential for stroke by reducing neuronal oxidative stress, mitochondrial damage, degeneration and apoptosis in ischemic stroke. |
2023-06-19 |
2023-08-14 |
Not clear |
| Donghai Li, Tianpeng He, Yue Zhang, Junru Liu, Haiyu Zhao, Dongliang Wang, Quanchao Wang, Yuan Yuan, Shengxiang Zhan. Melatonin regulates microglial polarization and protects against ischemic stroke-induced brain injury in mice. Experimental neurology. 2023-06-10. PMID:37301531. |
our results demonstrated that melatonin treatment reduced the infarct volume, prevented neuronal loss and apoptosis, and improved neurological deficits after ischemic stroke. |
2023-06-10 |
2023-08-14 |
mouse |
| Mengru Zhang, Jianjun Wang, Jinfang Li, Fanxin Kong, Songjun Li. miR-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating HDAC9. Translational neuroscience. vol 14. issue 1. 2023-05-30. PMID:37250142. |
mir-101-3p improves neuronal morphology and attenuates neuronal apoptosis in ischemic stroke in young mice by downregulating hdac9. |
2023-05-30 |
2023-08-14 |
mouse |
| Qian Suo, Lidong Deng, Tingting Chen, Shengju Wu, Lin Qi, Ze Liu, Tingting He, Heng-Li Tian, Wanlu Li, Yaohui Tang, Guo-Yuan Yang, Zhijun Zhan. Optogenetic Activation of Astrocytes Reduces Blood-Brain Barrier Disruption via IL-10 In Stroke. Aging and disease. 2023-05-17. PMID:37196130. |
we found for the first time that interleukin-10 derived from optogenetic-activated astrocytes protected blood-brain barrier integrity by decreasing the activity of matrix metallopeptidase 2 and attenuated neuronal apoptosis, which provided a novel therapeutic approach and target in the acute stage of ischemic stroke. |
2023-05-17 |
2023-08-14 |
rat |
| Kongwei Guo, Yanxing Shang, Zhao Wang, Yu Li, Jinliang Chen, Baofeng Zhu, Dongmei Zhang, Jianrong Che. BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion. International immunopharmacology. vol 119. 2023-05-12. PMID:37172425. |
brg1 is a key factor in the process of apoptosis and oxidative damage; however, its role in the pathophysiology of ischemic stroke is unclear. |
2023-05-12 |
2023-08-14 |
mouse |
| Ni-Na Song, Ying Zhao, Chuang Sun, Jun Zhang, Guang-Jun Lin, Xiao-Wei Yin, Chun-Ye M. DUSP10 alleviates ischemic stroke-induced neuronal damage by restricting p38/JNK pathway. Behavioural brain research. 2023-05-10. PMID:37164190. |
neuronal apoptosis is considered one of the hallmarks of ischemic stroke. |
2023-05-10 |
2023-08-14 |
mouse |
| Yang You, Jianpei Xu, Yipu Liu, Haichun Li, Laozhi Xie, Chuchu Ma, Yinzhe Sun, Shiqiang Tong, Kaifan Liang, Songlei Zhou, Fenfen Ma, Qingxiang Song, Wenze Xiao, Kaikai Fu, Chengxiang Dai, Suke Li, Jigang Lei, Qiyong Mei, Xiaoling Gao, Jun Che. Tailored Apoptotic Vesicle Delivery Platform for Inflammatory Regulation and Tissue Repair to Ameliorate Ischemic Stroke. ACS nano. 2023-04-26. PMID:37099675. |
this work presents a platform architecture that integrates apoptosis induction, drug loading, and functionalized proteome regulation, followed by targeting modification, enabling the creation of an apoptotic vesicle delivery system to treat ischemic stroke. |
2023-04-26 |
2023-08-14 |
Not clear |
| Shenghua Lin, Xin Liu, Aonan Sun, Huiliang Liang, Zhen Li, Suyan Ye, Honglin Ma, Wei Fan, Chuanlin Shen, Meng Jin, Qiuxia H. Qilong capsule alleviates ponatinib-induced ischemic stroke in a zebrafish model by regulating coagulation, inflammation and apoptosis. Journal of ethnopharmacology. 2023-04-22. PMID:37086871. |
qilong capsule alleviates ponatinib-induced ischemic stroke in a zebrafish model by regulating coagulation, inflammation and apoptosis. |
2023-04-22 |
2023-08-14 |
zebrafish |
| Fang-Fang Zhang, Liang Zhang, Lin Zhao, Yu Lu, Xin Dong, Yan-Qi Liu, Yu Li, Shuang Guo, Si-Yuan Zheng, Ying Xiao, Yu-Zhu Jian. The circular RNA Neural regeneration research. vol 18. issue 10. 2023-04-14. PMID:37056143. |
taken together, these findings demonstrate the mechanism by which circrap1b inhibits neuronal apoptosis in acute ischemic stroke. |
2023-04-14 |
2023-08-14 |
mouse |
| Lisha Chang, Wan Zhang, Songxin Shi, Yanbo Peng, Dali Wang, Li Zhang, Jiang Zhan. Retraction Note: microRNA-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting KLF5-mediated activation of the JNK signaling pathway. Molecular medicine (Cambridge, Mass.). vol 29. issue 1. 2023-04-13. PMID:37055736. |
retraction note: microrna-195 attenuates neuronal apoptosis in rats with ischemic stroke through inhibiting klf5-mediated activation of the jnk signaling pathway. |
2023-04-13 |
2023-08-14 |
rat |
| Shakiba Azami, Fatemeh Forouzanfa. Potential role of Nigella Sativa and its Constituent (Thymoquinone) in Ischemic Stroke. Current molecular medicine. 2023-04-11. PMID:37038292. |
ischemic stroke is a complex pathological process involving a series of mechanisms such as ros accumulation, ca2 + overload, inflammation, and apoptosis. |
2023-04-11 |
2023-08-14 |
Not clear |
| Jian Liu, Jingyi Sun, Yanan Song, Mengyue Wang, Peng Zhao, Wendi Wang, Mingfeng Yang, Ying Wang, Yuqiang Song, Baoliang Su. Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery. ACS chemical neuroscience. 2023-04-10. PMID:37038049. |
pbzyme inhibited the activation of macrophages and the release of inflammatory factors in the brain, promoted the polarization of microglia to m2, inhibited neuronal apoptosis, and promoted the recovery of neurological function after ischemic stroke. |
2023-04-10 |
2023-08-14 |
Not clear |
| Xiuping Chen, Yi Zhang, Qian Ding, Yanru He, Hui L. Role of IL-17A in different stages of ischemic stroke. International immunopharmacology. vol 117. 2023-04-04. PMID:37012860. |
in the acute phase of ischemic stroke, il-17a mediates neuronal injury through neutrophil chemotaxis to the site of injury, the induction of neuronal apoptosis, and activation of the calpain-trpc-6 (transient receptor potential channel-6) pathway. |
2023-04-04 |
2023-08-14 |
Not clear |
| Zhongqing Liu, Zhaojun Wang, Zhanchi Zhu, Jing Hong, Leisha Cui, Ying Hao, Guosheng Cheng, Rui Ta. Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery. Advanced healthcare materials. 2023-03-31. PMID:37001492. |
many neurons undergo apoptosis after ischemic stroke. |
2023-03-31 |
2023-08-14 |
rat |
| Jianzhuang Li, Yanmei Qiu, Chunlin Zhang, Hailing Wang, Rentang Bi, Yanhao Wei, Yanan Li, Bo H. The role of protein glycosylation in the occurrence and outcome of acute ischemic stroke. Pharmacological research. 2023-03-12. PMID:36907285. |
following ischemic stroke, the level of brain protein glycosylation becomes dynamically regulated, which significantly affects stroke outcome through influencing inflammatory response, excitotoxicity, neuronal apoptosis, and blood-brain barrier disruption. |
2023-03-12 |
2023-08-14 |
Not clear |
| Yan Huang, Xing Zhang, Ling Chen, Bo Xu Ren, Feng Ru Tan. Frontiers in bioscience (Landmark edition). vol 28. issue 2. 2023-03-03. PMID:36866558. |
ischemic stroke and cranial radiotherapy may induce brain inflammatory response, oxidative stress, apoptosis and neuronal loss, and impairment of neurogenesis. |
2023-03-03 |
2023-08-14 |
Not clear |