| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Mei Xia, Yu Duan, Yue-Ping Wang, Rui-Xue Han, Yin-Feng Dong, Si-Yuan Jiang, Yu Zheng, Chen Qiao, Lei Cao, Xiao Lu, Ming L. Vagus nerve stimulation as a promising neuroprotection for ischemic stroke via α7nAchR-dependent inactivation of microglial NLRP3 inflammasome. Acta pharmacologica Sinica. 2024-03-20. PMID:38504011. |
previous studies have shown that vagus nerve stimulation (vns) exerts neuroprotection in ischemic stroke by inhibiting neuroinflammation and apoptosis. |
2024-03-20 |
2024-03-23 |
mouse |
| Chan-Juan Liu, Peng San. Progress of researches on mechanisms of acupuncture underlying improvement of cerebral ischemia-reperfusion injury by regulating calcium overload. Zhen ci yan jiu = Acupuncture research. vol 49. issue 3. 2024-03-19. PMID:38500328. |
ischemic stroke is currently the most common type of stroke, and the key pathological link is cerebral ischemia-reperfusion injury (ciri), while the key factor leading to apoptosis and necrosis of ischemic nerve cells is calcium overload. |
2024-03-19 |
2024-03-21 |
Not clear |
| Tianshu Liu, Yan Wang, Mengfan Zhang, Jin Zhang, Naijin Kang, Linlin Zheng, Zhiying Din. The Optimization Design of Macrophage Membrane Camouflaging Liposomes for Alleviating Ischemic Stroke Injury through Intranasal Delivery. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474179. |
network pharmacology experiments predicted that mm-lip-rg3/pns could regulate multiple signaling pathways and treat ischemic stroke by reducing apoptosis and inflammatory responses. |
2024-03-13 |
2024-03-15 |
rat |
| Lina Wang, Zhenzhen Qu, Qian Sun, Zhuofeng Mao, Peipei Si, Weiping Wan. 4-Hydroxysesamin, a Modified Natural Compound, Attenuates Neuronal Apoptosis After Ischemic Stroke via Inhibiting MAPK Pathway. Neuropsychiatric disease and treatment. vol 20. 2024-03-12. PMID:38469210. |
4-hydroxysesamin, a modified natural compound, attenuates neuronal apoptosis after ischemic stroke via inhibiting mapk pathway. |
2024-03-12 |
2024-03-14 |
Not clear |
| Yunling Yu, Xinglan Liao, Xinyu Xie, Qihua Li, Xuehong Chen, Ruizhen Li. The role of neuroglial cells communication in ischemic stroke. Brain research bulletin. 2024-02-29. PMID:38423190. |
apoptosis of oligodendrocytes due to ischemic hypoxia leads to white matter injury, causing long-term cognitive dysfunction, and promoting oligodendrogenesis is a crucial direction for achieving functional recovery in ischemic stroke. |
2024-02-29 |
2024-03-03 |
Not clear |
| b' P Josi\\xc4\\x87 Dominovi\\xc4\\x87, M Dobrivojevi\\xc4\\x87 Radmilovi\\xc4\\x87, S Srako\\xc4\\x8di\\xc4\\x87, I Mi\\xc5\\xa1eri\\xc4\\x87, S \\xc5\\xa0koki\\xc4\\x87, S Gajovi\\xc4\\x8. Validation and application of caged Z-DEVD-aminoluciferin bioluminescence for assessment of apoptosis of wild type and TLR2-deficient mice after ischemic stroke. Journal of photochemistry and photobiology. B, Biology. vol 253. 2024-02-25. PMID:38402658.' |
validation and application of caged z-devd-aminoluciferin bioluminescence for assessment of apoptosis of wild type and tlr2-deficient mice after ischemic stroke. |
2024-02-25 |
2024-02-28 |
mouse |
| b' P Josi\\xc4\\x87 Dominovi\\xc4\\x87, M Dobrivojevi\\xc4\\x87 Radmilovi\\xc4\\x87, S Srako\\xc4\\x8di\\xc4\\x87, I Mi\\xc5\\xa1eri\\xc4\\x87, S \\xc5\\xa0koki\\xc4\\x87, S Gajovi\\xc4\\x8. Validation and application of caged Z-DEVD-aminoluciferin bioluminescence for assessment of apoptosis of wild type and TLR2-deficient mice after ischemic stroke. Journal of photochemistry and photobiology. B, Biology. vol 253. 2024-02-25. PMID:38402658.' |
the aim of this research article was to assess the caged z-devd-aminoluciferin substrate for in vivo monitoring of apoptosis after ischemic stroke in tlr2-deficient mice and their tlr2-expressing counterparts. |
2024-02-25 |
2024-02-28 |
mouse |
| b' P Josi\\xc4\\x87 Dominovi\\xc4\\x87, M Dobrivojevi\\xc4\\x87 Radmilovi\\xc4\\x87, S Srako\\xc4\\x8di\\xc4\\x87, I Mi\\xc5\\xa1eri\\xc4\\x87, S \\xc5\\xa0koki\\xc4\\x87, S Gajovi\\xc4\\x8. Validation and application of caged Z-DEVD-aminoluciferin bioluminescence for assessment of apoptosis of wild type and TLR2-deficient mice after ischemic stroke. Journal of photochemistry and photobiology. B, Biology. vol 253. 2024-02-25. PMID:38402658.' |
by utilizing bioluminescence of z-devd-aminoluciferin after ischemic stroke it was shown that tlr2-deficient mice had lower post-stroke apoptosis than tlr2-expressing wild type mice. |
2024-02-25 |
2024-02-28 |
mouse |
| Kunho Chung, Irfan Ullah, Yujong Yi, Eunhwa Kang, Gyeongju Yun, Seoyoun Heo, Minkyung Kim, Seong-Eun Chung, Seongjun Park, Jaeyeoung Lim, Minhyung Lee, Taiyoun Rhim, Sang-Kyung Le. Intranasal Delivery of Anti-Apoptotic siRNA Complexed with Fas-Signaling Blocking Peptides Attenuates Cellular Apoptosis in Brain Ischemia. Pharmaceutics. vol 16. issue 2. 2024-02-24. PMID:38399343. |
the fas-mediating extrinsic apoptosis pathway and the cytochrome c-mediating intrinsic apoptosis pathway are two major molecular mechanisms contributing to neuronal injury in ischemic stroke. |
2024-02-24 |
2024-02-26 |
rat |
| Jina Jiang, Tingting Qi, Li Li, Yunzhi Pan, Lijuan Huang, Lijuan Zhu, Dongyang Zhang, Xiaoqing Ma, Yinghui Qi. MRPS9-Mediated Regulation of the PI3K/Akt/mTOR Pathway Inhibits Neuron Apoptosis and Protects Ischemic Stroke. Journal of molecular neuroscience : MN. vol 74. issue 1. 2024-02-21. PMID:38381220. |
mrps9-mediated regulation of the pi3k/akt/mtor pathway inhibits neuron apoptosis and protects ischemic stroke. |
2024-02-21 |
2024-02-23 |
mouse |
| Jina Jiang, Tingting Qi, Li Li, Yunzhi Pan, Lijuan Huang, Lijuan Zhu, Dongyang Zhang, Xiaoqing Ma, Yinghui Qi. MRPS9-Mediated Regulation of the PI3K/Akt/mTOR Pathway Inhibits Neuron Apoptosis and Protects Ischemic Stroke. Journal of molecular neuroscience : MN. vol 74. issue 1. 2024-02-21. PMID:38381220. |
neuronal apoptosis is crucial in the pathophysiology of ischemic stroke (is), albeit its underly24ing mechanism remaining elusive. |
2024-02-21 |
2024-02-23 |
mouse |
| b' Murat \\xc3\\x87ak\\xc4\\xb1r, Hikmet Sa\\xc3\\xa7mac\\xc4\\xb. The relationship of salusins with Parkinson\'s Disease, Alzheimer\'s Disease, and acute ischemic stroke: A preliminary study. Neuroscience letters. 2024-02-13. PMID:38350537.' |
neuroinflammation, oxidative stress, and apoptosis play important roles in the pathophysiology of alzheimer's disease (ad), parkinson's disease (pd), and acute ischemic stroke (ais). |
2024-02-13 |
2024-02-16 |
Not clear |
| Lu Tang, Yue Yin, Hening Liu, Mengliang Zhu, Yuqi Cao, Jingwen Feng, Cong Fu, Zixuan Li, Weijie Shu, Jifan Gao, Xing-Jie Liang, Wei Wan. Blood-Brain Barrier-Penetrating and Lesion-Targeting Nanoplatforms Inspired by the Pathophysiological Features for Synergistic Ischemic Stroke Therapy. Advanced materials (Deerfield Beach, Fla.). 2024-02-12. PMID:38346008. |
as a result, pp@pcl exerted desirable therapeutic efficacy in injured pc12 neuronal cells and rat model of ischemic stroke, which significantly attenuated neuronal apoptosis, reduced infarct volume, and recovered neurological functions, bringing new insights into exploiting promising treatment strategies for cerebral ischemic stroke management. |
2024-02-12 |
2024-02-15 |
rat |
| Rehnuma Islam, Jan-Eric Ahlfors, Ricky Siu, Humna Noman, Roya Akbary, Cindi M Morshea. Inhibition of Apoptosis in a Model of Ischemic Stroke Leads to Enhanced Cell Survival, Endogenous Neural Precursor Cell Activation and Improved Functional Outcomes. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339065. |
inhibition of apoptosis in a model of ischemic stroke leads to enhanced cell survival, endogenous neural precursor cell activation and improved functional outcomes. |
2024-02-10 |
2024-02-12 |
mouse |
| Linyu Wu, Zixuan Tan, Lei Su, Fang Dong, Guangyu Xu, Feng Zhan. Transcutaneous electrical acupoint stimulation alleviates cerebral ischemic injury through the TLR4/MyD88/NF-κ B pathway. Frontiers in cellular neuroscience. vol 17. 2024-01-26. PMID:38273974. |
this study was to explore whether transcutaneous electrical acupoint stimulation (teas) treatment could mediate inflammation, apoptosis, and pyroptosis of neuronal cells and microglia activation through the tlr4/myd88/nf-κb pathway in the early stage of ischemic stroke. |
2024-01-26 |
2024-01-28 |
Not clear |
| Xiaosong He, Xin Wang, Hui Wang, Tao Wang, Fuhan Yang, Yuchen Chen, Zifei Pei, Yuting Bai, Wen Li, Zheng Wu, Gong Che. NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke. Aging and disease. 2024-01-25. PMID:38270116. |
following the changes of signaling pathways in endothelial cells, neurod1 effectively protected bbb integrity, attenuated neuroinflammation, inhibited neuron apoptosis and rescued motor deficits after ischemic stroke. |
2024-01-25 |
2024-01-27 |
mouse |
| Guangchen Xu, Ge Liu, Ziyu Wang, Yunman Li, Weirong Fan. Circular RNAs: Promising Treatment Targets and Biomarkers of Ischemic Stroke. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203348. |
this review provides a summary of 31 circrnas involved in the pathophysiological processes of apoptosis, autophagy, inflammation, oxidative stress, and angiogenesis following ischemic stroke. |
2024-01-11 |
2024-01-13 |
Not clear |
| Sungeun Chung, Yujong Yi, Irfan Ullah, Kunho Chung, Seongjun Park, Jaeyeoung Lim, Chaeyeon Kim, Seon-Hong Pyun, Minkyung Kim, Dokyoung Kim, Minhyung Lee, Taiyoun Rhim, Sang-Kyung Le. Systemic Treatment with Fas-Blocking Peptide Attenuates Apoptosis in Brain Ischemia. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203830. |
apoptosis plays a crucial role in neuronal injury, with substantial evidence implicating fas-mediated cell death as a key factor in ischemic strokes. |
2024-01-11 |
2024-01-13 |
mouse |
| Bin Sun, Jing Luo, Zhen Li, Dongfeng Chen, Qizhang Wang, Wenwen S. Muscone alleviates neuronal injury via increasing stress granules formation and reducing apoptosis in acute ischemic stroke. Experimental neurology. 2024-01-07. PMID:38185313. |
muscone alleviates neuronal injury via increasing stress granules formation and reducing apoptosis in acute ischemic stroke. |
2024-01-07 |
2024-01-10 |
rat |
| Yuqian Zhang, Shenghan Gao, Shengnan Xia, Haiyan Yang, Xinyu Bao, Qingxiu Zhang, Yun X. Linarin ameliorates ischemia-reperfusion injury by the inhibition of endoplasmic reticulum stress targeting AKR1B1. Brain research bulletin. 2024-01-05. PMID:38181967. |
neuroinflammation and neuronal apoptosis mediated by endoplasmic reticulum stress are some of the important pathological mechanisms in ischemic stroke. |
2024-01-05 |
2024-01-08 |
Not clear |