| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Willem M Otte, Pascal Bielefeld, Rick M Dijkhuizen, Kees P J Brau. Focal neocortical epilepsy affects hippocampal volume, shape, and structural integrity: a longitudinal MRI and immunohistochemistry study in a rat model. Epilepsia. vol 53. issue 7. 2012-09-14. PMID:22691119. |
our goal was to longitudinally characterize the development of bilateral hippocampal pathology in an experimental neocortical focal epilepsy model. |
2012-09-14 |
2023-08-12 |
rat |
| Julio Lachos, Michela Zattoni, Heinz-Gregor Wieser, Jean-Marc Fritschy, Thomas Langmann, Gerd Schmitz, Mariella Errede, Daniela Virgintino, Yasuhiro Yonekawa, Karl Fre. Characterization of the gene expression profile of human hippocampus in mesial temporal lobe epilepsy with hippocampal sclerosis. Epilepsy research and treatment. vol 2011. 2012-08-31. PMID:22937234. |
one of the main putative causes of therapy refractory epilepsy in mesial temporal lobe epilepsy (mtle) with hippocampal sclerosis is the overexpression of multidrug transporters (mdts) at the blood-brain barrier (bbb). |
2012-08-31 |
2023-08-12 |
human |
| Clarissa Fantin Cavarsan, Renata Della Torre Avanzi, Claudio Marcos Queiroz, Gilberto Fernando Xavier, Luiz Eugênio Mello, Luciene Covola. m1 Acetylcholine Receptor Expression is Decreased in Hippocampal CA1 region of Aged Epileptic Animals. Aging and disease. vol 2. issue 4. 2012-08-23. PMID:22396882. |
in the present study, we investigated the possible additive effects of epilepsy and aging on the expression of m1 muscarinic acetylcholine receptors (achr) in the rat hippocampus. |
2012-08-23 |
2023-08-12 |
rat |
| Wen-Ting Wang, Dan Han, Zu-Yu Zou, Jun Zen. [Epileptiform activity of the anterior dorsal hippocampal network induced by acute tetanization of the right posterior dorsal hippocampus of the rat]. Sheng li xue bao : [Acta physiologica Sinica]. vol 55. issue 3. 2012-08-20. PMID:12817304. |
acute tetanization (60 hz, 2 s, 0.4 - 0.6 ma) of the right posterior dorsal hippocampus (atpdh) was used to induce hippocampal epilepsy. |
2012-08-20 |
2023-08-12 |
rat |
| Guang Zhe Huang, Catherine S Woolle. Estradiol acutely suppresses inhibition in the hippocampus through a sex-specific endocannabinoid and mGluR-dependent mechanism. Neuron. vol 74. issue 5. 2012-08-17. PMID:22681685. |
the steroid 17β-estradiol (e2) is well known to influence hippocampal functions such as memory, affective behaviors, and epilepsy. |
2012-08-17 |
2023-08-12 |
Not clear |
| Ingmar Blümcke, Roland Coras, Hajime Miyata, Cigdem Ozkar. Defining clinico-neuropathological subtypes of mesial temporal lobe epilepsy with hippocampal sclerosis. Brain pathology (Zurich, Switzerland). vol 22. issue 3. 2012-08-13. PMID:22497612. |
hippocampal sclerosis (hs) is the most frequent cause of drug-resistant focal epilepsies (ie, mesial temporal lobe epilepsy with hippocampal sclerosis; mtle-hs), and presents a broad spectrum of electroclinical, structural and molecular pathology patterns. |
2012-08-13 |
2023-08-12 |
Not clear |
| Cary H Leung, Michele A Kliem, Brenten L Heeke, Scott W J McPhee, Thais Federici, Brooke R Snyder, Nicholas M Bouli. Assessment of hippocampal adeno-associated viral vector gene delivery via frameless stereotaxis in a nonhuman primate. Stereotactic and functional neurosurgery. vol 89. issue 5. 2012-08-09. PMID:21849811. |
expression of the neuropeptide galanin in hippocampal neurons reduces seizures in the kainic acid rodent model of epilepsy. |
2012-08-09 |
2023-08-12 |
human |
| A Voulgari-Kokota, R Fairless, M Karamita, V Kyrargyri, V Tseveleki, M Evangelidou, B Delorme, P Charbord, R Diem, L Prober. Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function. Experimental neurology. vol 236. issue 1. 2012-08-07. PMID:22561409. |
the adoptive transfer of egfp(+)msc in a mouse kainic acid epilepsy model also provided neuroprotection against glutamate excitotoxicity in vivo, as shown by reduced neuron damage and glial cell activation in the hippocampus. |
2012-08-07 |
2023-08-12 |
mouse |
| Fadi Ghareeb, Hugues Duffa. Intractable epilepsy in paralimbic Word Health Organization Grade II gliomas: should the hippocampus be resected when not invaded by the tumor? Journal of neurosurgery. vol 116. issue 6. 2012-08-06. PMID:22404676. |
intractable epilepsy in paralimbic word health organization grade ii gliomas: should the hippocampus be resected when not invaded by the tumor? |
2012-08-06 |
2023-08-12 |
Not clear |
| Fadi Ghareeb, Hugues Duffa. Intractable epilepsy in paralimbic Word Health Organization Grade II gliomas: should the hippocampus be resected when not invaded by the tumor? Journal of neurosurgery. vol 116. issue 6. 2012-08-06. PMID:22404676. |
however, no studies have examined the impact of hippocampal resection on chronic epilepsy when the hippocampus is not invaded by grade ii gliomas. |
2012-08-06 |
2023-08-12 |
Not clear |
| Fadi Ghareeb, Hugues Duffa. Intractable epilepsy in paralimbic Word Health Organization Grade II gliomas: should the hippocampus be resected when not invaded by the tumor? Journal of neurosurgery. vol 116. issue 6. 2012-08-06. PMID:22404676. |
here, the authors compared the epileptological outcomes and return to work in 2 groups of patients who underwent surgery with or without hippocampectomy for paralimbic grade ii gliomas eliciting intractable epilepsy despite no tumoral involvement of the hippocampus. |
2012-08-06 |
2023-08-12 |
Not clear |
| Robert Kuba, Milan Brázdil, Ivan Rekto. Postictal psychosis and its electrophysiological correlates in invasive EEG: a case report study and literature review. Epilepsy & behavior : E&B. vol 23. issue 4. 2012-07-30. PMID:22436442. |
both patients had mesial temporal epilepsy associated with hippocampal sclerosis. |
2012-07-30 |
2023-08-12 |
Not clear |
| Judith Rohde, Timo Kirschstein, Wiebke Wilkars, Lorenz Müller, Tursonjan Tokay, Katrin Porath, Roland A Bender, Rüdiger Köhlin. Upregulation of presynaptic mGluR2, but not mGluR3 in the epileptic medial perforant path. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22202905. |
these results demonstrate that chronic epilepsy not only causes downregulation of mglurs in the hippocampus, but may also lead to enhanced expression of these receptors - at least in the medial perforant path. |
2012-07-27 |
2023-08-12 |
rat |
| Xinjian Zhu, Xiao Han, Julie A Blendy, Brenda E Porte. Decreased CREB levels suppress epilepsy. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21867753. |
following se, brain derived neurotrophic factor (bdnf) and inducible camp early repressor (icer) mrnas are differentially up-regulated in the hippocampus and cortex of the creb(α∆) mutants compared to wild-type mice, which may be contributing to differences in the severity of epilepsy. |
2012-07-23 |
2023-08-12 |
mouse |
| Casper R Gøtzsche, Litsa Nikitidou, Andreas T Sørensen, Mikkel V Olesen, Gunnar Sørensen, Søren H O Christiansen, Mikael Ängehagen, David P D Woldbye, Merab Kokai. Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21884793. |
we recently demonstrated that recombinant adeno-associated viral vector-induced hippocampal overexpression of neuropeptide y receptor, y2, exerts a seizure-suppressant effect in kindling and kainate-induced models of epilepsy in rats. |
2012-07-23 |
2023-08-12 |
rat |
| Paul S Buckmaste. Mossy cell dendritic structure quantified and compared with other hippocampal neurons labeled in rats in vivo. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612804. |
mossy cells are likely to contribute to normal hippocampal function and to the pathogenesis of neurologic disorders that involve the hippocampus, including epilepsy. |
2012-07-16 |
2023-08-12 |
rat |
| Patricia Szo. Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612810. |
epilepsy is not considered a neurodegenerative disorder, but the hippocampus is severely affected in temporal lobe epilepsy. |
2012-07-16 |
2023-08-12 |
Not clear |
| Alexander A Sosunov, Xiaoping Wu, Robert A McGovern, David G Coughlin, Charles B Mikell, Robert R Goodman, Guy M McKhan. The mTOR pathway is activated in glial cells in mesial temporal sclerosis. Epilepsia. vol 53 Suppl 1. 2012-07-16. PMID:22612812. |
different from human sclerotic epileptic hippocampus, astrogliosis in the chronic rat pilocarpine model of epilepsy was not characterized by glial cells with mtor activation. |
2012-07-16 |
2023-08-12 |
human |
| Darrin J Lee, Mike S Hsu, Marcus M Seldin, Janetta L Arellano, Devin K Binde. Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis. Experimental neurology. vol 235. issue 1. 2012-06-29. PMID:22361023. |
previous studies have demonstrated increased seizure duration and slowed potassium kinetics in aqp4(-/-) mice, and redistribution of aqp4 in hippocampal specimens from patients with chronic epilepsy. |
2012-06-29 |
2023-08-12 |
mouse |
| Jose F Tellez-Zenteno, Samuel Wieb. Hippocampal stimulation in the treatment of epilepsy. Neurosurgery clinics of North America. vol 22. issue 4. 2012-06-25. PMID:21939845. |
hippocampal stimulation in the treatment of epilepsy. |
2012-06-25 |
2023-08-12 |
Not clear |